Substrate: TRKA (Required for high affinity binding to nerve growth factor , neurotrophin-3 and neurotrophin-4/5r.)
Seq-ID: P04629 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
MINT-6793941   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transmembrane receptor protein tyrosine kinase activity,
neurotrophin receptor activity,
ATP binding		 endosome,
integral to plasma membrane		 activation of adenylate cyclase activity,
Ras protein signal transduction,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 496 LQGHIIENPQYFSDACVHHIK TRKA 11159935
LTP
1.00
 FRS2 PTB;
GRB2 SH2;
PLCG1 SH2;
SHC1 PTB;
SHC1 SH2		 -
0.16
 - medium
Y 496 LQGHIIENPQYFSDACVHHIK TRKA 8155326
LTP
1.00
 FRS2 PTB;
GRB2 SH2;
PLCG1 SH2;
SHC1 PTB;
SHC1 SH2		 -
0.16
 - medium
Y 676 IGDFGMSRDIYSTDYYRVGGR TRKA 11159935
LTP
1.00
 - TyrKc
0.11
 - medium
Y 680 GMSRDIYSTDYYRVGGRTMLP TRKA 11159935
LTP
1.00
 - TyrKc
0.12
 - medium
Y 681 MSRDIYSTDYYRVGGRTMLPI TRKA 11159935
LTP
1.00
 - TyrKc
0.11
 - medium
Y 757 ERPRACPPEVYAIMRGCWQRE - 16319926
LTP
1.00
 PIK3R1 SH2;
SH2D1A SH2		 TyrKc
0.24
 - medium
Y 791 LQALAQAPPVYLDVLG      TRKA 11159935
LTP
1.00
 MATK SH2;
PLCG1 SH2;
SHC1 SH2		 -
0.11
 - medium
Y 791 LQALAQAPPVYLDVLG      TRKA 8155326
LTP
1.00
 MATK SH2;
PLCG1 SH2;
SHC1 SH2		 -
0.11
 - medium

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