Substrate: TTK (Dual specificity protein kinase)
Seq-ID: P33981 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50598   TBB5_HUMAN
MINT-50599   TACC2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
identical protein binding,
ATP binding,
protein tyrosine kinase activity		 spindle positive regulation of cell proliferation,
protein amino acid phosphorylation,
positive regulation of pathway-restricted SMAD protein phosphorylation,
mitotic spindle organization,
mitotic cell cycle spindle assembly checkpoint
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 17 IKNKFKNEDLTDELSLNKISA - 18669648
HTP
0.76
 - -
0.40
 - medium
S 265 FGRVPVNLLNSPDCDVKTDDS - 18669648
HTP
0.85
 - -
0.44
 - medium
S 305 VPGSKPSGNDSCELRNLKSVQ - 18669648
HTP
0.93
 - -
0.58
 - medium
S 439 FDPKSICKTPSSNTLDDYMSC - 18669648
HTP
0.00
 - -
0.34
 - medium
S 805 YVLGQLVGLNSPNSILKAAKT - 18669648
HTP
0.81
 - -
0.24
 - medium
S 808 GQLVGLNSPNSILKAAKTLYE - 18669648
HTP
0.62
 - -
0.26
 - medium
S 821 KAAKTLYEHYSGGESHNSSSS - 18680479
LTP
1.00
 - -
0.53
 - medium

Substrate: TTK (Dual specificity protein kinase)
Seq-ID: P33981-1 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
identical protein binding,
ATP binding,
protein tyrosine kinase activity		 spindle positive regulation of cell proliferation,
protein amino acid phosphorylation,
positive regulation of pathway-restricted SMAD protein phosphorylation,
mitotic spindle organization,
mitotic cell cycle spindle assembly checkpoint
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 468 TLDDYMSCFRTPVVKNDFPPA CDK2 17804818
LTP
 - - -
0.31
 --
T 676 GIANQMQPDTTSVVKDSQVGT TTK 19120698
LTP
 - - S_TKc
0.43
 --
T 676 GIANQMQPDTTSVVKDSQVGT TTK 18680479
LTP
 - - S_TKc
0.43
 --
T 676 GIANQMQPDTTSVVKDSQVGT TTK 18083840
LTP
 - - S_TKc
0.43
 --
T 676 GIANQMQPDTTSVVKDSQVGT TTK 18545697
LTP
 - - S_TKc
0.43
 --
T 686 TSVVKDSQVGTVNYMPPEAIK TTK 19120698
LTP
 - - S_TKc
0.39
 3CEK 43.84%
T 686 TSVVKDSQVGTVNYMPPEAIK - 18680479
LTP
 - - S_TKc
0.39
 3CEK 43.84%

Substrate: TTK (Dual specificity protein kinase)
Seq-ID: P42282 [Drosophila melanogaster]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
specific transcriptional repressor activity,
chromatin binding,
zinc ion binding,
protein binding		 polytene chromosome,
nucleus		 transcription,
locomotion involved in locomotory behavior,
brain morphogenesis,
peripheral nervous system development,
regulation of cell shape,
startle response,
dorsal appendage formation,
negative regulation of transcription, DNA-dependent,
compound eye corneal lens morphogenesis,
compound eye cone cell differentiation,
R1/R6 development,
cell fate determination,
dendrite morphogenesis,
R7 cell development,
inter-male aggressive behavior
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 203 KRKRGRPRKLSGSSNGTGNDY - 18327897
HTP
0.22
 - AT_hook
0.87
 - medium
S 203 KRKRGRPRKLSGSSNGTGNDY - 18327897
HTP
0.22
 - AT_hook
0.87
 - medium
S 205 KRGRPRKLSGSSNGTGNDYDD - 18327897
HTP
0.22
 - AT_hook
0.86
 - medium
S 205 KRGRPRKLSGSSNGTGNDYDD - 18327897
HTP
0.22
 - AT_hook
0.86
 - medium
S 206 RGRPRKLSGSSNGTGNDYDDF - 18327897
HTP
0.13
 - -
0.85
 - medium
S 206 RGRPRKLSGSSNGTGNDYDDF - 18327897
HTP
0.13
 - -
0.85
 - medium
T 209 PRKLSGSSNGTGNDYDDFDRE - 18327897
HTP
0.13
 - -
0.83
 - medium
T 209 PRKLSGSSNGTGNDYDDFDRE - 18327897
HTP
0.13
 - -
0.83
 - medium
S 682 FTPPKDIGAFSPLKYLISAAA - 18327897
HTP
0.21
 - -
0.28
 - medium
S 682 FTPPKDIGAFSPLKYLISAAA - 18327897
HTP
0.21
 - -
0.28
 - medium

Substrate: TTK (Dual specificity protein kinase)
Seq-ID: Q98T92 [Xenopus laevis]
Download:fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
ATP binding		 protein amino acid phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 844 RILGQLIGLNSPNSISRAAKN MAPK3 16950116
LTP
0.97
 MOD_ProDKin_1
 - -
0.35
 - low

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