Substrate: Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))
Seq-ID: P04177 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
amino acid binding,
tyrosine 3-monooxygenase activity,
ferrous iron binding,
ferric iron binding,
dopamine binding		 mitochondrion,
cytosol,
synaptic vesicle,
terminal button		 neurotransmitter biosynthetic process,
oxidation reduction,
response to hypoxia,
response to steroid hormone stimulus,
protein homotetramerization,
dopamine biosynthetic process from tyrosine
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 8    MPTPSAPSPQPKGFRRAV CDK_group 2570779
LTP
0.36
 - -
0.86
 - medium
S 19 PQPKGFRRAVSEQDAKQAEAV CaM-KII_group 1672315
LTP
1.00
 - -
0.72
 - medium
S 31 QDAKQAEAVTSPRFIGRRQSL - 1672315
LTP
0.84
 - -
0.55
 - medium
S 40 TSPRFIGRRQSLIEDARKERE PKA_group 2874140
LTP
1.00
 MOD_PKA_1
 - -
0.52
 - medium
S 40 TSPRFIGRRQSLIEDARKERE PKC_group 2874140
LTP
1.00
 MOD_PKA_1
 - -
0.52
 - medium
S 40 TSPRFIGRRQSLIEDARKERE CaM-KII_group 2874140
LTP
1.00
 MOD_PKA_1
 - -
0.52
 - medium
S 153 AALLSSVRRVSDDVRSAREDK PKA_group 2874140
LTP
0.42
 MOD_PKA_1
 - -
0.31
 - medium

Substrate: Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))
Seq-ID: P07101 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
tyrosine 3-monooxygenase activity,
protein binding		 smooth endoplasmic reticulum,
perikaryon,
internal side of plasma membrane,
cytosol,
melanosome membrane,
nucleus		 synaptic transmission, dopaminergic,
embryonic camera-type eye morphogenesis,
neurotransmitter biosynthetic process,
oxidation reduction,
response to hypoxia,
heart morphogenesis,
learning,
eye photoreceptor cell development,
regulation of heart contraction,
visual perception,
norepinephrine biosynthetic process,
dopamine biosynthetic process from tyrosine,
locomotory behavior,
memory,
epinephrine biosynthetic process,
pigmentation,
response to ethanol
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 19 PQAKGFRRAVSELDAKQAEAI - 11359875
LTP
1.00
 - -
0.58
 - low
S 19 PQAKGFRRAVSELDAKQAEAI MAPKAPK2 7901013
LTP
1.00
 - -
0.58
 - low
S 19 PQAKGFRRAVSELDAKQAEAI CaM-KII_group 1680128
LTP
1.00
 - -
0.58
 - low
S 19 PQAKGFRRAVSELDAKQAEAI CaM-KII_alpha 1680128
LTP
1.00
 - -
0.58
 - low
S 40 MVRGQGAPGPSLTGSPWPGTA - 11359875
LTP
 - - -
0.78
 - low
S 40 MVRGQGAPGPSLTGSPWPGTA MAPKAPK2 7901013
LTP
 - - -
0.78
 - low
S 71 RSPRFIGRRQSLIEDARKERE PKA_group 1680128
LTP
1.00
 MOD_PKA_1
 - -
0.61
 - low
S 71 RSPRFIGRRQSLIEDARKERE CaM-KII_alpha 1680128
LTP
1.00
 MOD_PKA_1
 - -
0.61
 - low

Substrate: Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))
Seq-ID: P17289 [Bos taurus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
iron ion binding,
tyrosine 3-monooxygenase activity		 neurotransmitter biosynthetic process,
oxidation reduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 19 PQAKGFRRAVSELDAKQAEAI CaM-KII_group 2568951
LTP
1.00
 - -
0.51
 - medium
S 40 MSPRFVGRRQSLIQDARKERE CaM-KII_group 2568951
LTP
1.00
 - COIL
0.52
 - medium

Substrate: Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))
Seq-ID: P24529 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
tyrosine 3-monooxygenase activity perikaryon,
nucleus		 synaptic transmission, dopaminergic,
eating behavior,
embryonic camera-type eye morphogenesis,
neurotransmitter biosynthetic process,
oxidation reduction,
learning,
eye photoreceptor cell development,
regulation of heart contraction,
visual perception,
heart development,
dopamine biosynthetic process from tyrosine,
locomotory behavior,
memory,
mating behavior
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 19 PQPKGFRRAVSEQDTKQAEAV - 16412098
LTP
1.00
 - -
0.74
 - medium
S 31 QDTKQAEAVTSPRFIGRRQSL CDK5 15447670
LTP
0.84
 - -
0.58
 - medium
S 31 QDTKQAEAVTSPRFIGRRQSL CDK5 15471880
LTP
0.84
 - -
0.58
 - medium
S 31 QDTKQAEAVTSPRFIGRRQSL - 16412098
LTP
0.84
 - -
0.58
 - medium
S 40 TSPRFIGRRQSLIEDARKERE - 16412098
LTP
1.00
 - -
0.52
 - medium
S 40 TSPRFIGRRQSLIEDARKERE - 15305880
LTP
1.00
 - -
0.52
 - medium

Valid HTML 4.01 Transitional