Substrate: VEGFR-1 (Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity.)
Seq-ID: P17948 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-6177086   LDLR_HUMAN
MINT-6539646   CBL_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
vascular endothelial growth factor receptor activity,
ATP binding,
growth factor binding		 cytoplasm,
integral to plasma membrane,
extracellular space		 positive regulation of vascular endothelial growth factor receptor signaling pathway,
female pregnancy,
peptidyl-tyrosine phosphorylation,
cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 794 KRSSSEIKTDYLSIIMDPDEV - 11741094
LTP
0.97
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2		 -
0.30
 - low
Y 794 KRSSSEIKTDYLSIIMDPDEV - 9398617
LTP
0.97
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2		 -
0.30
 - low
Y 1048 ICDFGLARDIYKNPDYVRKGD - 18083107
HTP
1.00
 - TyrKc
0.18
 - low
Y 1053 LARDIYKNPDYVRKGDTRLPL - 18083107
HTP
1.00
 - TyrKc
0.24
 - low
Y 1169 QANVQQDGKDYIPINAILTGN - 11513746
LTP
1.00
 PIK3R1 SH2;
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2		 -
0.30
 - low
Y 1169 QANVQQDGKDYIPINAILTGN - 9299537
LTP
1.00
 PIK3R1 SH2;
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2		 -
0.30
 - low
Y 1213 FNSGSSDDVRYVNAFKFMSLE FLT1 11513746
LTP
1.00
 GRB2 SH2;
NCK SH2;
PIK3R1 SH2;
PTPN11 SH2		 -
0.20
 - low
Y 1213 FNSGSSDDVRYVNAFKFMSLE FLT1 9722576
LTP
1.00
 GRB2 SH2;
NCK SH2;
PIK3R1 SH2;
PTPN11 SH2		 -
0.20
 - low
Y 1213 FNSGSSDDVRYVNAFKFMSLE - 9600074
LTP
1.00
 GRB2 SH2;
NCK SH2;
PIK3R1 SH2;
PTPN11 SH2		 -
0.20
 - low
Y 1242 LPNATSMFDDYQGDSSTLLAS FLT1 11513746
LTP
0.05
 - -
0.35
 - low
Y 1327 KIACCSPPPDYNSVVLYSTPP FLT1 11513746
LTP
0.46
 - -
0.29
 - low
Y 1333 PPPDYNSVVLYSTPPI      FLT1 11513746
LTP
0.46
 CRK SH2;
NCK SH2;
PLCG_group SH2		 -
0.37
 - low
Y 1333 PPPDYNSVVLYSTPPI      FLT1 9722576
LTP
0.46
 CRK SH2;
NCK SH2;
PLCG_group SH2		 -
0.37
 - low
Y 1333 PPPDYNSVVLYSTPPI      - 9600074
LTP
0.46
 CRK SH2;
NCK SH2;
PLCG_group SH2		 -
0.37
 - low

Substrate: VEGFR-1 (Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity.)
Seq-ID: P35969 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-6177157   LDLR_HUMAN
MINT-6177187   PLCG1_MOUSE
MINT-6177216   CBL_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
vascular endothelial growth factor receptor activity,
identical protein binding,
ATP binding		 integral to plasma membrane patterning of blood vessels,
cell migration,
sprouting angiogenesis,
peptidyl-tyrosine phosphorylation,
cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 1263 PLLKRFTWTETKPKASMKIDL - 17203969
HTP
0.05
 - -
0.28
 - medium

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