Substrate: eIF-4E (eukaryotic translation initation factor 4E (eIF-4E) (from PhosphoBase))
Seq-ID: P06730 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-13665   MKNK1_HUMAN
MINT-17286   IF4G1_HUMAN
MINT-19025   4EBP2_HUMAN
MINT-19057   4EBP1_HUMAN
MINT-1956046   4ET_HUMAN
MINT-6741139   G3BP1_HUMAN
MINT-7718723   SUMO1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
translation initiation factor activity,
RNA cap binding,
protein binding		 eukaryotic translation initiation factor 4F complex,
mRNA cap binding complex,
cytosol		 positive regulation of mitotic cell cycle,
G1/S transition of mitotic cell cycle,
interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 53 WALWFFKNDKSKTWQANLRLI - 3112145
LTP
0.88
 - IF4E
0.10
 1IPB 83.61%
S 209 SHADTATKSGSTTKNRFVV   - 7782323
LTP
0.97
 - IF4E
0.45
 1IPB 50.82%
S 209 SHADTATKSGSTTKNRFVV   Mnk1 11463832
LTP
0.97
 - IF4E
0.45
 1IPB 50.82%
S 209 SHADTATKSGSTTKNRFVV   Mnk2 11463832
LTP
0.97
 - IF4E
0.45
 1IPB 50.82%
S 209 SHADTATKSGSTTKNRFVV   - 11723111
LTP
0.97
 - IF4E
0.45
 1IPB 50.82%

Substrate: eIF-4E (eukaryotic translation initation factor 4E (eIF-4E) (from PhosphoBase))
Seq-ID: P07260 [Saccharomyces cerevisiae]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-2340619   CAF20_YEAST
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphatidylinositol-3-phosphate binding,
translation initiation factor activity,
RNA binding,
protein binding		 ribosome,
eukaryotic translation initiation factor 4F complex,
stress granule,
nucleus		 regulation of cell cycle,
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 2          MSVEEVSKKFEE CK2_group 7592868
LTP
0.67
 - -
0.28
 --
S 15 EVSKKFEENVSVDDTTATPKT CK2_group 7592868
LTP
0.18
 - IF4E
0.53
 --

Substrate: eIF-4E (eukaryotic translation initation factor 4E (eIF-4E) (from PhosphoBase))
Seq-ID: P63073 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-1899476   EIF3B_MOUSE
MINT-1954700   IF4G1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
translation initiation factor activity,
RNA binding,
protein binding		 mRNA cap binding complex,
cytoplasm
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 209 SHADTATKSGSTTKNRFVV   Mnk1 9878069
LTP
0.96
 - IF4E
0.45
 1IPB 50.82%
S 209 SHADTATKSGSTTKNRFVV   PKC_alpha 8662663
LTP
0.96
 - IF4E
0.45
 1IPB 50.82%

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