Substrate: p21-Rac1 (GTPase)
Seq-ID: P63000 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-19610   NONO_MOUSE
MINT-19641   RBM39_MOUSE
MINT-19851   EVI5_MOUSE
MINT-51615   FHOD1_HUMAN
MINT-2490678   KPCA_HUMAN
MINT-4298452   GDIR1_HUMAN
MINT-4298550   SET_HUMAN
MINT-4507979   FRK_HUMAN
MINT-6504419   RTKN_HUMAN
MINT-6743318   VAV_HUMAN
MINT-7145306   ARHG7_HUMAN
MINT-7217644   PAK1_HUMAN
MINT-7219402   SPN90_HUMAN
MINT-7229970   PLCG1_HUMAN
MINT-7230086   PAK2_HUMAN
MINT-7288697   FLNB_HUMAN
MINT-7305963   DOCK1_HUMAN
MINT-7305987   DOCK2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
thioesterase binding,
GTPase activity,
GTP binding,
GTP-dependent protein binding		 plasma membrane,
cytosol,
melanosome		 localization within membrane,
induction of apoptosis by extracellular signals,
negative regulation of receptor-mediated endocytosis,
positive regulation of lamellipodium assembly,
apoptosis,
cellular component movement,
actin filament polymerization,
anatomical structure morphogenesis,
inflammatory response,
regulation of hydrogen peroxide metabolic process,
cell-matrix adhesion,
positive regulation of Rho protein signal transduction,
regulation of respiratory burst,
lamellipodium assembly,
small GTPase mediated signal transduction,
ruffle organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 71 QEDYDRLRPLSYPQTDVFLIC PKB_group 10617634
LTP
1.00
 MOD_PKB_1
 - RHO
0.11
 1MH1 6.56%
S 71 QEDYDRLRPLSYPQTDVFLIC - 18669648
HTP
1.00
 MOD_PKB_1
 - RHO
0.11
 1MH1 6.56%
T 167 CSALTQRGLKTVFDEAIRAVL - 18669648
HTP
0.22
 - RHO
0.10
 1MH1 45.21%

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