Substrate: p62DOK (Docking protein, common target of PTKs)
Seq-ID: P97465 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-45941   ITB7_HUMAN
MINT-45944   ITB2_HUMAN
MINT-61568   ITB3_HUMAN
MINT-6765422   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin receptor binding,
transmembrane receptor protein tyrosine kinase signaling protein activity		 cytoplasm MAPKKK cascade,
Ras protein signal transduction,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 146 SALEMLENSLYSPTWEGSQFW - 11042170
LTP
1.00
 - -
0.19
 - low
S 269 GQAQDILRTDSHDGETEGKTV - 19144319
HTP
1.00
 - -
0.79
 - low
Y 295 QDPLGSPPALYAEPLDSLRIP - 15592455
HTP
0.04
 - -
0.64
 - low
Y 314 IPPGPSQDSVYSDPLGSTPAG - 15592455
HTP
1.00
 - -
0.84
 - low
Y 336 GEGVHSKKPLYWDLYGHVQQQ - 15592455
HTP
1.00
 - -
0.46
 - low
Y 340 HSKKPLYWDLYGHVQQQLLKT - 15592455
HTP
0.22
 - -
0.41
 - low
Y 361 KLTDSKEDPIYDEPEGLAPAP - 15592455
HTP
1.00
 - -
0.85
 - low
Y 361 KLTDSKEDPIYDEPEGLAPAP Abl 15148308
LTP
1.00
 - -
0.85
 - low
Y 376 GLAPAPPRGLYDLPQEPRDAW - 15592455
HTP
1.00
 - -
0.68
 - low
Y 376 GLAPAPPRGLYDLPQEPRDAW - 19144319
HTP
1.00
 - -
0.68
 - low
Y 397 WCQARLKEEGYELPYNPATDD - 15592455
HTP
0.16
 - -
0.49
 - low
Y 401 RLKEEGYELPYNPATDDYAVP - 15592455
HTP
1.00
 - -
0.65
 - low
Y 408 ELPYNPATDDYAVPPPRSPKP - 15592455
HTP
1.00
 - -
0.81
 - low
Y 450 SKGFSSDTALYSQVQKSGTSG - 15592455
HTP
0.96
 - -
0.60
 - low

Substrate: p62DOK (Docking protein, common target of PTKs)
Seq-ID: Q99704 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-74512   ERBB2_HUMAN
MINT-7974670   DLG4_RAT
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin receptor binding cytosol,
perinuclear region of cytoplasm		 transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 146 SALEMLENSLYSPTWEGSQFW - 11042170
LTP
1.00
 CRKL SH2 -
0.21
 --
Y 203 QILEPLLSWPYTLLRRYGRDK - 12087092
LTP
1.00
 CRKL SH2;
INPP5D SH2		 PTBI
0.17
 2V76 5.24%
S 269 GQGHDVLRADSHEGEVAEGKL - 16094384
LTP
1.00
 - -
0.70
 --
S 269 GQGHDVLRADSHEGEVAEGKL - 18088087
HTP
1.00
 - -
0.70
 --
S 269 GQGHDVLRADSHEGEVAEGKL - 18669648
HTP
1.00
 - -
0.70
 --
S 281 EGEVAEGKLPSPPGPQELLDS - 18669648
HTP
0.14
 - -
0.83
 --
S 291 SPPGPQELLDSPPALYAEPLD - 18669648
HTP
0.04
 - -
0.69
 --
Y 296 QELLDSPPALYAEPLDSLRIA - 12087092
LTP
0.05
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 296 QELLDSPPALYAEPLDSLRIA - 10688886
LTP
0.05
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 12087092
LTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.66
 --
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 10688886
LTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.66
 --
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 18083107
HTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.66
 --
Y 337 GEGVQRKKPLYWDLYEHAQQQ - 16497976
HTP
1.00
 CRKL SH2;
PTPN11 SH2		 -
0.48
 --
Y 341 QRKKPLYWDLYEHAQQQLLKA - 12087092
LTP
0.23
 CRKL SH2 -
0.41
 --
Y 362 KLTDPKEDPIYDEPEGLAPVP - 12087092
LTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2		 -
0.82
 --
Y 362 KLTDPKEDPIYDEPEGLAPVP INSR 11551902
LTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2		 -
0.82
 --
Y 362 KLTDPKEDPIYDEPEGLAPVP - 10688886
LTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2		 -
0.82
 --
Y 362 KLTDPKEDPIYDEPEGLAPVP - 15592455
HTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2		 -
0.82
 --
Y 362 KLTDPKEDPIYDEPEGLAPVP - 16094384
HTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2		 -
0.82
 --
Y 377 GLAPVPPQGLYDLPREPKDAW - 12087092
LTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2		 -
0.62
 --
Y 377 GLAPVPPQGLYDLPREPKDAW - 10688886
LTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2		 -
0.62
 --
Y 377 GLAPVPPQGLYDLPREPKDAW - 15592455
HTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2		 -
0.62
 --
Y 377 GLAPVPPQGLYDLPREPKDAW - 16094384
HTP
1.00
 ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2		 -
0.62
 --
Y 398 WCQARVKEEGYELPYNPATDD - 12087092
LTP
0.17
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 398 WCQARVKEEGYELPYNPATDD INSR 11551902
LTP
0.17
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 398 WCQARVKEEGYELPYNPATDD - 10688886
LTP
0.17
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 398 WCQARVKEEGYELPYNPATDD - 15592455
HTP
0.17
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 398 WCQARVKEEGYELPYNPATDD - 16094384
HTP
0.17
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.48
 --
Y 402 RVKEEGYELPYNPATDDYAVP - 15592455
HTP
1.00
 CRKL SH2 -
0.64
 --
Y 409 ELPYNPATDDYAVPPPRSTKP - 12087092
LTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.72
 --
Y 409 ELPYNPATDDYAVPPPRSTKP - 10688886
LTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.72
 --
Y 409 ELPYNPATDDYAVPPPRSTKP - 15592455
HTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.72
 --
Y 409 ELPYNPATDDYAVPPPRSTKP - 16094384
HTP
1.00
 ABL1 SH2;
CRKL SH2;
RASA_group SH2		 -
0.72
 --
S 439 AFPEPGTATGSGIKSHNSALY - 15574499
LTP
0.90
 - -
0.69
 --
S 446 ATGSGIKSHNSALYSQVQKSG - 15574499
LTP
0.80
 - -
0.63
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 12087092
LTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 10852966
LTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 12522270
HTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 15592455
HTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 16094384
HTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 15659558
HTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
Y 449 SGIKSHNSALYSQVQKSGASG - 18083107
HTP
0.00
 CRKL SH2;
SH2D1A SH2		 -
0.59
 --
S 450 GIKSHNSALYSQVQKSGASGS - 15574499
LTP
1.00
 - -
0.58
 --

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