List of substrates found:

PYK2  Insulin receptor substrate 1  TRKA  c-kit  ErbB2 


Substrate: PYK2 (Focal adhesion kinase 2)
Seq-ID: Q14289 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 402 SESCSIESDIYAEIPDETLRR SYK 8816475
LTP
1.00
Fyn SH2;
MATK SH2;
Src SH2
-
0.37
--
Y 402 SESCSIESDIYAEIPDETLRR - 9560226
LTP
1.00
Fyn SH2;
MATK SH2;
Src SH2
-
0.37
--
Y 402 SESCSIESDIYAEIPDETLRR PYK2 15105428
LTP
1.00
Fyn SH2;
MATK SH2;
Src SH2
-
0.37
--

Substrate: Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)
Seq-ID: P35568 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 662 RHPQRVDPNGYMMMSPSGGCS - 15592455
HTP
1.00
Fyn SH2;
MATK SH2;
PIK3R1 SH2;
PTPN11 SH2
-
0.77
--

Substrate: TRKA (Required for high affinity binding to nerve growth factor , neurotrophin-3 and neurotrophin-4/5r.)
Seq-ID: P04629 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 791 LQALAQAPPVYLDVLG      TRKA 11159935
LTP
1.00
MATK SH2;
PLCG1 SH2;
SHC1 SH2
-
0.11
- medium
Y 791 LQALAQAPPVYLDVLG      TRKA 8155326
LTP
1.00
MATK SH2;
PLCG1 SH2;
SHC1 SH2
-
0.11
- medium

Substrate: c-kit (Receptor tyrosine kinase)
Seq-ID: P10721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 568 KVVEEINGNNYVYIDPTQLPY Kit 9799234
LTP
1.00
Fyn SH2;
MATK SH2;
PTPN11 SH2;
PTPN6 SH2;
SHC1 SH2
-
0.13
--
Y 570 VEEINGNNYVYIDPTQLPYDH Kit 9799234
LTP
1.00
Fyn SH2;
MATK SH2;
PTPN6 SH2;
SHC1 SH2
-
0.13
--
Y 721 ESSCSDSTNEYMDMKPGVSYV - N.N.
LTP
1.00
MATK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2
TyrKc
0.36
--
Y 721 ESSCSDSTNEYMDMKPGVSYV - 9038210
LTP
1.00
MATK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2
TyrKc
0.36
--

Substrate: ErbB2 (Receptor tyrosine kinase)
Seq-ID: P04626 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1248 KGTPTAENPEYLGLDVPV    ErbB2 11500516
LTP
1.00
MATK SH2 -
0.69
- low
Y 1248 KGTPTAENPEYLGLDVPV    - 17081983
HTP
1.00
MATK SH2 -
0.69
- low


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