a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	TRKA (Required for high affinity binding to nerve growth factor , neurotrophin-3 and neurotrophin-4/5r.)
Seq-ID:	P04629 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-6793941   PTN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transmembrane receptor protein tyrosine kinase activity, neurotrophin receptor activity, ATP binding endosome, integral to plasma membrane activation of adenylate cyclase activity, Ras protein signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	757	ERPRACPPEVYAIMRGCWQRE	-	16319926	LTP	1.00		PIK3R1 SH2; SH2D1A SH2	TyrKc	0.24	-	medium

Substrate:	CD150 (T cell antigen receptor)
Seq-ID:	Q13291 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process antigen binding, transmembrane receptor activity integral to membrane positive regulation of cell proliferation, lymphocyte activation, interspecies interaction between organisms
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	281	TTVEKKSLTIYAQVQKPGPLQ	Fyn	11806999	LTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.39	-	low
Y	281	TTVEKKSLTIYAQVQKPGPLQ	-	18083107	HTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.39	-	low
Y	307	FPAQDPCTTIYVAATEPVPES	Fyn	11806999	LTP	1.00		INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.40	-	low
Y	307	FPAQDPCTTIYVAATEPVPES	Lck	11806999	LTP	1.00		INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.40	-	low
Y	327	SVQETNSITVYASVTLPES	Fyn	11806999	LTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.38	-	low
Y	327	SVQETNSITVYASVTLPES	Lyn	15315965	LTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.38	-	low

Substrate:	p62DOK (Docking protein, common target of PTKs)
Seq-ID:	Q99704 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-74512   ERBB2_HUMAN MINT-7974670   DLG4_RAT
GO-Terms:	[show] Molecular Function Cellular Component Biological Process insulin receptor binding cytosol, perinuclear region of cytoplasm transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	449	SGIKSHNSALYSQVQKSGASG	-	12087092	LTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-
Y	449	SGIKSHNSALYSQVQKSGASG	-	10852966	LTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-
Y	449	SGIKSHNSALYSQVQKSGASG	-	12522270	HTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-
Y	449	SGIKSHNSALYSQVQKSGASG	-	15592455	HTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-
Y	449	SGIKSHNSALYSQVQKSGASG	-	16094384	HTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-
Y	449	SGIKSHNSALYSQVQKSGASG	-	15659558	HTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-
Y	449	SGIKSHNSALYSQVQKSGASG	-	18083107	HTP	0.00		CRKL SH2; SH2D1A SH2	-	0.59	-	-