Substrate: EGFR (Receptor for EGF and other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor,)
Seq-ID: P00533 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1172 SHQISLDNPDYQQDFFPKEAK EGFR 8845374
LTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1172 SHQISLDNPDYQQDFFPKEAK - 15302935
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1172 SHQISLDNPDYQQDFFPKEAK - 17081983
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1172 SHQISLDNPDYQQDFFPKEAK - 18083107
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--

Substrate: ALK (Receptor tyrosine kinase)
Seq-ID: Q9UM73 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1096 STIMTDYNPNYCFAGKTSSIS - 15592455
HTP
1.00
SHC3 PTB -
0.20
- medium
Y 1096 STIMTDYNPNYCFAGKTSSIS - 18083107
HTP
1.00
SHC3 PTB -
0.20
- medium
Y 1507 NKPTSLWNPTYGSWFTEKPTK - 15592455
HTP
0.21
SHC3 PTB -
0.62
- medium
Y 1507 NKPTSLWNPTYGSWFTEKPTK - 9819383
LTP
0.21
SHC3 PTB -
0.62
- medium
Y 1507 NKPTSLWNPTYGSWFTEKPTK - 11110708
LTP
0.21
SHC3 PTB -
0.62
- medium
Y 1507 NKPTSLWNPTYGSWFTEKPTK - 18083107
HTP
0.21
SHC3 PTB -
0.62
- medium

Substrate: RET (Probable receptor with tyrosine-protein kinase activity; important for development.)
Seq-ID: P07949 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1062 LPSTWIENKLYGMSDPNWPGE - 11470823
LTP
0.19
FRS2 PTB;
IRS1 PTB;
PIK3R1 SH2;
SHC1 PTB;
SHC1 SH2;
SHC3 PTB;
SHC3 SH2
-
0.43
--
Y 1062 LPSTWIENKLYGMSDPNWPGE RET 14711813
LTP
0.19
FRS2 PTB;
IRS1 PTB;
PIK3R1 SH2;
SHC1 PTB;
SHC1 SH2;
SHC3 PTB;
SHC3 SH2
-
0.43
--
Y 1062 LPSTWIENKLYGMSDPNWPGE RET 14981541
LTP
0.19
FRS2 PTB;
IRS1 PTB;
PIK3R1 SH2;
SHC1 PTB;
SHC1 SH2;
SHC3 PTB;
SHC3 SH2
-
0.43
--


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