a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

Tpo-R  INF-alpha REC  EGFR  G-CSF-R  BMX  GH-R  IL-6R (gp130)  Leptin receptor  STAT 3  ErbB2  c-met  FAK 

Substrate:	Tpo-R (Thrombopoietin R mlp belongs to the hematopoietic R superfamily)
Seq-ID:	P40238 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cytokine receptor activity integral to plasma membrane cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	631	IANHSYLPLSYWQQP	-	9122198	LTP	0.68		STAT3 SH2	-	0.23	-	medium

Substrate:	INF-alpha REC (Interferon receptor)
Seq-ID:	P17181 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-73134   TYK2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process type I interferon receptor activity integral to plasma membrane blood coagulation, JAK-STAT cascade, response to virus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	466	AAKVFLRCINYVFFPSLKPSS	Tyk2	8605876	LTP	1.00		STAT1 SH2; STAT2 SH2; STAT3 SH2; TYK2 SH2	-	0.03	-	low
Y	466	AAKVFLRCINYVFFPSLKPSS	Tyk2	8700538	LTP	1.00		STAT1 SH2; STAT2 SH2; STAT3 SH2; TYK2 SH2	-	0.03	-	low

Substrate:	EGFR (Receptor for EGF and other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor,)
Seq-ID:	P00533 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-16802   GRB10_HUMAN MINT-50935   1433Z_HUMAN MINT-51101   ANXA1_HUMAN MINT-51490   ARBK1_HUMAN MINT-60973   CBL_HUMAN MINT-61486   CRKL_HUMAN MINT-61487   CSK_HUMAN MINT-61490   STA5B_HUMAN MINT-61540   GRB2_HUMAN MINT-68514   PDC6I_HUMAN MINT-74427   ABL1_HUMAN MINT-74438   ABL2_HUMAN MINT-74460   ANS1A_HUMAN MINT-74469   APBB1_HUMAN MINT-74479   DP13A_HUMAN MINT-74487   BMX_HUMAN MINT-74497   CRK_HUMAN MINT-74535   FES_HUMAN MINT-74551   IRS1_HUMAN MINT-74555   IRS4_HUMAN MINT-74562   JAK2_HUMAN MINT-74566   SH2B3_HUMAN MINT-74572   JIP1_HUMAN MINT-74587   NCK1_HUMAN MINT-74593   NUMB_HUMAN MINT-74594   NUMBL_HUMAN MINT-74606   P85A_HUMAN MINT-74630   P85B_HUMAN MINT-74659   P55G_HUMAN MINT-74678   PLCG1_HUMAN MINT-74685   PLCG2_HUMAN MINT-74687   PTK6_HUMAN MINT-74689   PTN11_HUMAN MINT-74711   RASA1_HUMAN MINT-74717   SH2B1_HUMAN MINT-74720   SH22A_HUMAN MINT-74732   SHC1_HUMAN MINT-74746   SLAP1_HUMAN MINT-74763   KSYK_HUMAN MINT-74790   TLN1_HUMAN MINT-74807   ZAP70_HUMAN MINT-1788719   ERBB2_HUMAN MINT-6169667   ESR1_HUMAN MINT-6170031   SOS1_MOUSE MINT-6170198   SH3G2_HUMAN MINT-6170268   SH3K1_HUMAN MINT-6793358   PTN1_HUMAN MINT-7980526   TM1L1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process epidermal growth factor receptor activity, protein heterodimerization activity, identical protein binding, receptor signaling protein tyrosine kinase activity, double-stranded DNA binding, ATP binding, protein phosphatase binding, actin filament binding, MAP/ERK kinase kinase activity Shc-EGFR complex, endosome, basolateral plasma membrane, integral to membrane, extracellular space, nucleus activation of phospholipase C activity, protein insertion into membrane, response to UV-A, positive regulation of nitric oxide biosynthetic process, positive regulation of cell migration, positive regulation of cyclin-dependent protein kinase activity involved in G1/S, positive regulation of catenin protein nuclear translocation, regulation of nitric-oxide synthase activity, positive regulation of protein kinase B signaling cascade, ossification, positive regulation of epithelial cell proliferation, activation of phospholipase A2 activity by calcium-mediated signaling, cell-cell adhesion, regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphorylation, positive regulation of MAP kinase activity, cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1092	IDDTFLPVPEYINQSVPKRPA	EGFR	8845374	LTP	0.05		GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG1 SH2; PTPN6 SH2; RASA_group SH2; STAT3 SH2	-	0.57	-	-
Y	1092	IDDTFLPVPEYINQSVPKRPA	-	15302935	HTP	0.05		GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG1 SH2; PTPN6 SH2; RASA_group SH2; STAT3 SH2	-	0.57	-	-
Y	1092	IDDTFLPVPEYINQSVPKRPA	-	17081983	HTP	0.05		GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG1 SH2; PTPN6 SH2; RASA_group SH2; STAT3 SH2	-	0.57	-	-
Y	1092	IDDTFLPVPEYINQSVPKRPA	-	18083107	HTP	0.05		GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG1 SH2; PTPN6 SH2; RASA_group SH2; STAT3 SH2	-	0.57	-	-
Y	1110	RPAGSVQNPVYHNQPLNPAPS	EGFR	8845374	LTP	1.00		GRB2 SH2; PLCG1 SH2; RASA_group SH2; SHC1 PTB; Src SH2; STAT3 SH2	-	0.80	-	-
Y	1110	RPAGSVQNPVYHNQPLNPAPS	-	15302935	HTP	1.00		GRB2 SH2; PLCG1 SH2; RASA_group SH2; SHC1 PTB; Src SH2; STAT3 SH2	-	0.80	-	-

Substrate:	G-CSF-R (Granulocyte colony stimulating factor receptor)
Seq-ID:	P40223 [Mus musculus]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cytokine receptor activity integral to membrane neutrophil chemotaxis, cell adhesion
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	728	NGSLPALVQAYVLQGDPREIS	-	8608222	LTP	1.00		PTPN11 SH2; STAT3 SH2	-	0.41	-	medium
Y	728	NGSLPALVQAYVLQGDPREIS	-	10329697	LTP	1.00		PTPN11 SH2; STAT3 SH2	-	0.41	-	medium
Y	768	ESPTSPGVMQYIRSDSTQPLL	-	8608222	LTP	1.00		STAT3 SH2	-	0.64	-	medium

Substrate:	G-CSF-R (Granulocyte colony stimulating factor receptor)
Seq-ID:	Q99062 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cytokine receptor activity extracellular region, integral to plasma membrane cell adhesion, defense response
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	727	TCGLPTLVQTYVLQGDPRAVS	-	12133942	LTP	1.00		STAT3 SH2	-	0.36	-	medium

Substrate:	BMX (Tyrosine kinase)
Seq-ID:	P51813 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-68564   GAB1_HUMAN MINT-68565   P53_HUMAN MINT-74487   EGFR_HUMAN MINT-74488   ERBB2_HUMAN MINT-7254948   CRK_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process metal ion binding, non-membrane spanning protein tyrosine kinase activity, ATP binding, signal transducer activity, protein binding cytosol protein amino acid phosphorylation, mesoderm development
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	224	AQYDSNSKKIYGSQPNFNMQY	BTK	12573241	LTP	-		STAT3 SH2	-	0.44	-	medium
Y	224	AQYDSNSKKIYGSQPNFNMQY	TEC	12573241	LTP	-		STAT3 SH2	-	0.44	-	medium

Substrate:	GH-R (Growth hormon receptor)
Seq-ID:	P10912 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-6797534   DUS7_HUMAN MINT-6797749   PTN2_HUMAN MINT-6797775   PTN9_HUMAN MINT-6797788   PTPRB_HUMAN MINT-6797829   PTN1_HUMAN MINT-6797890   PTN3_HUMAN MINT-7250542   NCK1_HUMAN MINT-7252318   P85A_HUMAN MINT-7252594   PLCG1_HUMAN MINT-7254526   CRK_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein homodimerization activity, protein kinase binding, peptide hormone binding, growth factor binding, proline-rich region binding growth hormone receptor complex, integral to plasma membrane, cell surface, extracellular space valine metabolic process, activation of JAK2 kinase activity, oxaloacetate metabolic process, creatinine metabolic process, isoleucine metabolic process, positive regulation of tyrosine phosphorylation of Stat3 protein, taurine metabolic process, positive regulation of tyrosine phosphorylation of Stat5 protein, response to estradiol stimulus, insulin-like growth factor receptor signaling pathway, allantoin metabolic process, fatty acid metabolic process, positive regulation of multicellular organism growth, response to cycloheximide, citrate metabolic process, activation of MAPK activity, multicellular organismal metabolic process, 2-oxoglutarate metabolic process, succinate metabolic process, growth hormone receptor signaling pathway, endocytosis, creatine metabolic process, receptor internalization
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	487	NPSSLSNIDFYAQVSDITPAG	JAK2	9121492	LTP	1.00		CISH SH2; GRB10 SH2; SOCS2 SH2; STAT3 SH2; STAT5 SH2	-	0.42	-	low
Y	534	CQENFLMDNAYFCEADAKKCI	-	9121492	LTP	0.93		GRB10 SH2; STAT3 SH2; STAT5 SH2	-	0.16	-	low
Y	534	CQENFLMDNAYFCEADAKKCI	-	8647880	LTP	0.93		GRB10 SH2; STAT3 SH2; STAT5 SH2	-	0.16	-	low
Y	566	IQPSLNQEDIYITTESLTTAA	-	9121492	LTP	1.00		GRB10 SH2; STAT3 SH2; STAT5 SH2	-	0.47	-	low
Y	566	IQPSLNQEDIYITTESLTTAA	-	8647880	LTP	1.00		GRB10 SH2; STAT3 SH2; STAT5 SH2	-	0.47	-	low
Y	627	PDKEFLSSCGYVSTDQLNKIM	-	9121492	LTP	1.00		STAT3 SH2; STAT5 SH2	-	0.29	-	low
Y	627	PDKEFLSSCGYVSTDQLNKIM	-	8647880	LTP	1.00		STAT3 SH2; STAT5 SH2	-	0.29	-	low

Substrate:	IL-6R (gp130) (gp130 is shared by members of the IL-6 family)
Seq-ID:	P40189 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process ciliary neurotrophic factor receptor activity, protein homodimerization activity, interleukin-27 receptor activity, ciliary neurotrophic factor receptor binding extracellular region, oncostatin-M receptor complex, interleukin-6 receptor complex, extracellular space, ciliary neurotrophic factor receptor complex positive regulation vascular endothelial growth factor production, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of anti-apoptosis, leukemia inhibitory factor signaling pathway, response to cytokine stimulus, negative regulation of interleukin-6-mediated signaling pathway, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of adaptive immune response, ciliary neurotrophic factor-mediated signaling pathway, positive regulation of T cell proliferation, positive regulation of osteoblast differentiation, interleukin-27-mediated signaling pathway, positive regulation of acute inflammatory response, positive regulation of cardiac muscle hypertrophy
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	767	VQYSTVVHSGYRHQVPSVQVF	-	8612579	LTP	1.00		STAT3 SH2	-	0.45	-	medium
Y	767	VQYSTVVHSGYRHQVPSVQVF	-	10661409	LTP	1.00		STAT3 SH2	-	0.45	-	medium
Y	814	GGDGILPRQQYFKQNCSQHES	-	8612579	LTP	1.00		STAT3 SH2	-	0.61	-	medium
Y	814	GGDGILPRQQYFKQNCSQHES	-	10661409	LTP	1.00		STAT3 SH2	-	0.61	-	medium
Y	905	AATDEGMPKSYLPQTVRQGGY	-	8612579	LTP	1.00		STAT1 SH2; STAT3 SH2	-	0.70	-	medium
Y	905	AATDEGMPKSYLPQTVRQGGY	-	10661409	LTP	1.00		STAT1 SH2; STAT3 SH2	-	0.70	-	medium
Y	915	YLPQTVRQGGYMPQ	-	8612579	LTP	1.00		STAT1 SH2; STAT3 SH2	-	0.64	-	medium
Y	915	YLPQTVRQGGYMPQ	-	10661409	LTP	1.00		STAT1 SH2; STAT3 SH2	-	0.64	-	medium

Substrate:	Leptin receptor (Receptor for the obesity factor Leptin; it belongs to the cytokine receptor family)
Seq-ID:	P48356 [Mus musculus]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-2576222   SOCS3_MOUSE MINT-2576447   STA5A_MOUSE MINT-2576732   PLCG1_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cytokine receptor activity integral to plasma membrane cholesterol metabolic process, negative regulation of hydrolase activity
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1138	LGTSGENFVPYMPQFQTCSTH	-	10799542	LTP	0.97		STAT3 SH2	-	0.29	-	-

Substrate:	Leptin receptor (Receptor for the obesity factor Leptin; it belongs to the cytokine receptor family)
Seq-ID:	P48357 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-63769   PIN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cytokine receptor activity plasma membrane, integral to membrane energy reserve metabolic process
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1141	GTSSKKTFASYMPQFQTCSTQ	-	14625304	LTP	1.00		STAT3 SH2	-	0.29	-	medium

Substrate:	STAT 3 (Transcription factor)
Seq-ID:	P40763 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-74756   ERBB2_HUMAN MINT-6764613   PTN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein dimerization activity, calcium ion binding, hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity, protein kinase binding, transcription activator activity, transcription factor binding, sequence-specific DNA binding transcription factor activity plasma membrane, cytoplasm, nucleus interleukin-6-mediated signaling pathway, eating behavior, glucose homeostasis, cellular component movement, response to estradiol stimulus, temperature homeostasis, interspecies interaction between organisms, JAK-STAT cascade involved in growth hormone signaling pathway, sexual reproduction, eye photoreceptor cell differentiation, negative regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	705	PEADPGSAAPYLKTKFICVTP	-	9083098	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	11429593	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	JAK2	9582023	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	15592455	HTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	12244095	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	14551213	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	ALK	11850821	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	9305919	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	18083107	HTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%

Substrate:	ErbB2 (Receptor tyrosine kinase)
Seq-ID:	P04626 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-61505   P85B_HUMAN MINT-74429   ABL1_HUMAN MINT-74444   ABL2_HUMAN MINT-74462   ANS1A_HUMAN MINT-74470   APBB1_HUMAN MINT-74486   BLNK_HUMAN MINT-74488   BMX_HUMAN MINT-74498   CRK_HUMAN MINT-74502   CRKL_HUMAN MINT-74508   DAB1_HUMAN MINT-74512   DOK1_HUMAN MINT-74521   SPT6H_HUMAN MINT-74533   FER_HUMAN MINT-74538   FGR_HUMAN MINT-74540   GRAP2_HUMAN MINT-74542   GRB2_HUMAN MINT-74544   GRB7_HUMAN MINT-74553   IRS1_HUMAN MINT-74556   IRS4_HUMAN MINT-74558   ITK_HUMAN MINT-74561   JAK1_HUMAN MINT-74567   SH2B3_HUMAN MINT-74575   JIP1_HUMAN MINT-74582   MATK_HUMAN MINT-74590   NCK2_HUMAN MINT-74610   P85A_HUMAN MINT-74664   P55G_HUMAN MINT-74680   PLCG1_HUMAN MINT-74686   PLCG2_HUMAN MINT-74691   PTN11_HUMAN MINT-74712   RASA1_HUMAN MINT-74713   RIN1_HUMAN MINT-74722   SH22A_HUMAN MINT-74723   SH23A_HUMAN MINT-74724   3BP2_HUMAN MINT-74737   SHC1_HUMAN MINT-74747   SLAP1_HUMAN MINT-74755   STAT1_HUMAN MINT-74756   STAT3_HUMAN MINT-74769   KSYK_HUMAN MINT-74777   TEC_HUMAN MINT-74781   TENC1_HUMAN MINT-74786   TENS3_HUMAN MINT-74793   TLN1_HUMAN MINT-74794   TXK_HUMAN MINT-74802   VAV2_HUMAN MINT-1788719   EGFR_HUMAN MINT-1901925   LAP2_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process epidermal growth factor receptor activity, ErbB-3 class receptor binding, protein heterodimerization activity, DNA binding, protein C-terminus binding, identical protein binding, receptor signaling protein tyrosine kinase activity, ATP binding, protein phosphatase binding receptor complex, integral to membrane, nucleus, perinuclear region of cytoplasm regulation of angiogenesis, transcription, regulation of transcription, phosphoinositide 3-kinase cascade, phosphoinositide-mediated signaling, heart development, positive regulation of cell adhesion, protein amino acid autophosphorylation, positive regulation of epithelial cell proliferation, wound healing, positive regulation of MAP kinase activity, cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1139	APLTCSPQPEYVNQPDVRPQP	ErbB2	11500516	LTP	1.00		GRB2 SH2; GRB7 SH2; Src SH2; STAT3 SH2	-	0.85	-	low
Y	1222	AFSPAFDNLYYWDQDPPERGA	ErbB2	11500516	LTP	1.00		SHC_group SH2; STAT3 SH2	-	0.68	-	low

Substrate:	c-met (Receptor tyrosine kinase for hepatocyte growth factor.)
Seq-ID:	P08581 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-18299   RANB9_HUMAN MINT-58374   GAB1_MOUSE MINT-58404   GAB1_HUMAN MINT-6539587   CBL_HUMAN MINT-6787689   PTN1_HUMAN MINT-6798640   PTN11_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process hepatocyte growth factor receptor activity, ATP binding, protein binding integral to plasma membrane, basal plasma membrane protein amino acid phosphorylation, multicellular organismal development, cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1313	LQPEYCPDPLYEVMLKCWHPK	-	7708691	LTP	0.97		PIK3R1 SH2; STAT3 SH2	TyrKc	0.10	3F66	15.28%
Y	1313	LQPEYCPDPLYEVMLKCWHPK	-	10069803	LTP	0.97		PIK3R1 SH2; STAT3 SH2	TyrKc	0.10	3F66	15.28%

Substrate:	FAK (Focal adhesion kinase)
Seq-ID:	Q05397 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-17602   LYN_HUMAN MINT-74938   BCAR1_HUMAN MINT-3381308   SRC_HUMAN MINT-6794892   PTN1_HUMAN MINT-7294020   P53_HUMAN MINT-7385708   SRC_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process non-membrane spanning protein tyrosine kinase activity, ATP binding, SH2 domain binding, signal transducer activity focal adhesion, cytosol, cytoskeleton signal complex assembly, integrin-mediated signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	397	HAVSVSETDDYAEIIDEEDTY	FAK	7509446	LTP	1.00		Fyn SH2; GRB2 SH2; GRB7 SH2; NCK SH2; PIK3R1 SH2; Src SH2; STAT3 SH2	-	0.49	-	-
Y	397	HAVSVSETDDYAEIIDEEDTY	-	17192257	HTP	1.00		Fyn SH2; GRB2 SH2; GRB7 SH2; NCK SH2; PIK3R1 SH2; Src SH2; STAT3 SH2	-	0.49	-	-
Y	397	HAVSVSETDDYAEIIDEEDTY	-	18083107	HTP	1.00		Fyn SH2; GRB2 SH2; GRB7 SH2; NCK SH2; PIK3R1 SH2; Src SH2; STAT3 SH2	-	0.49	-	-
Y	925	ANLDRSNDKVYENVTGLVKAV	-	12370821	LTP	1.00		GRB2 SH2; STAT3 SH2	Focal_AT	0.45	1K04	39.30%
Y	925	ANLDRSNDKVYENVTGLVKAV	-	7997267	LTP	1.00		GRB2 SH2; STAT3 SH2	Focal_AT	0.45	1K04	39.30%