List of substrates found:


Substrate: ATRIP (Required for checkpoint signaling after DNA damage)
Seq-ID: Q8WXE1 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 68 DDLEELDTLASQALSQCPAAA ATR 15451423
LTP
1.00
MOD_PIKK_1
- -
0.62
- medium
S 72 ELDTLASQALSQCPAAARDVS ATR 15451423
LTP
0.12
MOD_PIKK_1
- -
0.64
- medium

Substrate: BRCA1 (Breast cancer type 1 susceptibility protein)
Seq-ID: P38398 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 1423 ELEAVLEQHGSQPSNSYPSII ATR 11278964
LTP
1.00
MOD_PIKK_1
- COIL
0.74
--
S 1423 ELEAVLEQHGSQPSNSYPSII ATR 11114888
LTP
1.00
MOD_PIKK_1
- COIL
0.74
--
S 1457 QSTSEKAVLTSQKSSEYPISQ ATR 11278964
LTP
1.00
MOD_PIKK_1
- -
0.74
--
S 1524 SGSLQNRNYPSQEELIKVVDV ATR 11278964
LTP
1.00
MOD_PIKK_1
- -
0.62
--

Substrate: CHK1 (Serine/threonine-protein kinase Chk1)
Seq-ID: O14757 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 317 SSEENVKYSSSQPEPRTGLSL ATR 11390642
LTP
0.96
MOD_PIKK_1
- -
0.56
--
S 345 IDKLVQGISFSQPTCPDHMLL ATR 11390642
LTP
1.00
MOD_PIKK_1
SFN 14-3-3;
YWHAZ 14-3-3
-
0.30
--
S 345 IDKLVQGISFSQPTCPDHMLL ATR 10859164
LTP
1.00
MOD_PIKK_1
SFN 14-3-3;
YWHAZ 14-3-3
-
0.30
--
S 345 IDKLVQGISFSQPTCPDHMLL ATR 15533933
LTP
1.00
MOD_PIKK_1
SFN 14-3-3;
YWHAZ 14-3-3
-
0.30
--

Substrate: CREB (cAMP response element binding protein (CREB).)
Seq-ID: P16220 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 121 SQESVDSVTDSQKRREILSRR ATR 15073328
LTP
1.00
MOD_PIKK_1
- pKID
0.73
- low
S 121 SQESVDSVTDSQKRREILSRR ATR 16293623
LTP
1.00
MOD_PIKK_1
- pKID
0.73
- low

Substrate: E2F-1 (Transcription factor)
Seq-ID: Q01094 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 31 GAGALRLLDSSQIVIISAAQD ATR 11459832
LTP
0.14
MOD_PIKK_1
- -
0.33
- medium

Substrate: Mdm2 (Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2. -) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2))
Seq-ID: Q00987 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 407 PSTSSSIIYSSQEDVKEFERE ATR 14654783
LTP
1.00
MOD_PIKK_1
- -
0.53
- medium

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