List of substrates found:


Substrate: MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1))
Seq-ID: Q02750 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 23 PAPDGSAVNGTSSAETNLEAL MAP2K_group 7873542
LTP
0.17
- COIL
0.69
--
S 24 APDGSAVNGTSSAETNLEALQ MAP2K_group 7873542
LTP
0.44
- COIL
0.65
--
S 25 PDGSAVNGTSSAETNLEALQK MAP2K_group 7873542
LTP
0.02
- COIL
0.63
--
S 218 DFGVSGQLIDSMANSFVGTRS MAP2K_group 7873542
LTP
1.00
- S_TKc
0.20
3EQC 29.51%
S 298 PRPRTPGRPLSSYGMDSRPPM MAP2K_group 7873542
LTP
0.74
- S_TKc
0.69
--

Substrate: Mitogen-activated protein kinase 1 (S/T/Y kinase)
Seq-ID: P28482 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 185 DPDHDHTGFLTEYVATRWYRA MAP2K_group 11971971
LTP
1.00
- S_TKc
0.15
2GPH 73.97%

Substrate: Mitogen-activated protein kinase 10 (Mitogen activated protein kinase 10)
Seq-ID: P53779 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
JUN kinase activity,
MAP kinase kinase activity,
ATP binding,
protein binding
nucleoplasm
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 221 ARTAGTSFMMTPYVVTRYYRA MAP2K_group 15911620
LTP
1.00
- S_TKc
0.08
2O0U 45.21%

Substrate: Mitogen-activated protein kinase 14 (Mitogen-activated protein kinase 14)
Seq-ID: Q16539 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 180 GLARHTDDEMTGYVATRWYRA MAP2K_group 7750576
LTP
1.00
- S_TKc
0.18
2GFS 55.48%
Y 182 ARHTDDEMTGYVATRWYRAPE MAP2K_group 15735649
LTP
1.00
- S_TKc
0.19
2GFS 62.88%

Substrate: Mitogen-activated protein kinase 3 (S/T/Y kinase)
Seq-ID: P27361 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 202 DPEHDHTGFLTEYVATRWYRA MAP2K_group 11971971
LTP
1.00
- S_TKc
0.15
2ZOQ 26.71%
Y 204 EHDHTGFLTEYVATRWYRAPE MAP2K_group 11971971
LTP
1.00
- S_TKc
0.13
2ZOQ 48.47%

Substrate: Mitogen-activated protein kinase 9 (Mitogen-activated protein kinase 9)
Seq-ID: P45984 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 404 NDISSMSTEQTLASDTDSSLD MAP2K_group 11062067
LTP
1.00
- -
0.72
- low
S 407 SSMSTEQTLASDTDSSLDAST MAP2K_group 11062067
LTP
0.83
- -
0.77
- low

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