a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1))
Seq-ID:	P31938 [Mus musculus]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-16657   BRAF_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein serine/threonine kinase activity, MAP kinase kinase activity, ATP binding, protein tyrosine kinase activity, receptor signaling protein tyrosine phosphatase activity placenta blood vessel development, positive regulation of cell differentiation, cell motility, keratinocyte differentiation, labyrinthine layer development, activation of MAPK activity
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	292	DAAETPPRPRTPGRPLSSYGM	MAP3K1	8019005	LTP	0.12		-	S_TKc	0.78	-	-

Substrate:	MAP2K7 (MAP kinase kinase activity, protein binding)
Seq-ID:	O14733 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	[show] MINT-3391558   M3K1_HUMAN MINT-3391607   M3K5_HUMAN MINT-3391633   M3K7_HUMAN MINT-6629296   JIP1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, protein serine/threonine kinase activity, protein kinase binding, MAP kinase kinase activity, ATP binding, protein tyrosine kinase activity cytoplasm, nucleus protein amino acid phosphorylation, stress-activated MAPK cascade
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	271	DFGISGRLVDSKAKTRSAGCA	MAP3K1	9312068	LTP	1.00		-	S_TKc	0.19	-	-
T	275	SGRLVDSKAKTRSAGCAAYMA	MAP3K1	9312068	LTP	1.00		-	S_TKc	0.24	-	-

Substrate:	Mitogen-activated protein kinase kinase kinase 1 (Ser/Thr protein kinase family. MAP kinase family)
Seq-ID:	P53349 [Mus musculus]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	MINT-5209635   GRAP1_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, ATP binding, JUN kinase kinase activity, zinc ion binding camera-type eye development, regulation of cell migration, activation of JUN kinase activity, apoptotic mitochondrial changes, positive regulation of actin filament polymerization, transforming growth factor beta receptor signaling pathway, wound healing
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	1381	GAAARLASKGTGAGEFQGQLL	MAP3K1	9065412	LTP	1.00		-	S_TKc	0.26	-	medium
T	1381	GAAARLASKGTGAGEFQGQLL	MAP3K1	9078260	LTP	1.00		-	S_TKc	0.26	-	medium
T	1393	AGEFQGQLLGTIAFMAPEVLR	MAP3K1	9065412	LTP	1.00		-	S_TKc	0.14	-	medium