List of substrates found:


Substrate: CPI-17 (Inhibitor of PPP1CA)
Seq-ID: Q96A00 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
MINT-16604   KC1A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoprotein phosphatase inhibitor activity,
protein binding		 cytoplasm regulation of phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 38 GGLQKRHARVTVKYDRRELQR PKD1 15003508
LTP
1.00
 MOD_PKA_2
 - PP1_inhibitor
0.51
 - medium

Substrate: HDAC7A (Enzyme: Deacetylase)
Seq-ID: Q8WUI4 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-3296507   1433Z_HUMAN
MINT-3975829   1433S_HUMAN
MINT-6177417   KPCD2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C binding,
transcription repressor binding,
histone deacetylase activity		 histone deacetylase complex,
cytoplasm		 negative regulation of interleukin-2 production,
chromatin modification,
transcription,
positive regulation of cell migration involved in sprouting angiogenesis,
negative regulation of osteoblast differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 15623513
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18617643
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18509061
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium

Substrate: HSP27 (heat shock 27 kD protein (HSP 27) (from PhosphoBase))
Seq-ID: P04792 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14024   IF4G1_HUMAN
MINT-16434   CRYAA_HUMAN
MINT-16469   CRBB2_HUMAN
MINT-17168   CRYAB_HUMAN
MINT-65132   P53_HUMAN
MINT-65135   CA103_HUMAN
MINT-3305331   1433Z_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding spindle,
cell surface,
nucleus		 response to unfolded protein,
anti-apoptosis,
cellular component movement,
response to heat,
regulation of translational initiation,
cell death,
response to virus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 82 AYSRALSRQLSSGVSEIRHTA PKD1 15728188
LTP
0.30
 - -
0.42
 - medium

Substrate: PKC mu (Serine/threonine kinase)
Seq-ID: Q15139 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C activity,
metal ion binding,
ATP binding,
protein binding		 cytosol,
integral to plasma membrane		 protein amino acid phosphorylation,
signal transduction,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 205 NCSGVRRRRLSNVSLTGVSTI PKD1 10867018
LTP
1.00
 YWHAQ 14-3-3 -
0.31
 - medium
S 910 TEMKALGERVSIL         PKD1 10473617
LTP
0.00
 - -
0.28
 - medium
S 910 TEMKALGERVSIL         PKD1 14607845
LTP
0.00
 - -
0.28
 - medium
S 910 TEMKALGERVSIL         PKD1 16563698
LTP
0.00
 - -
0.28
 - medium

Substrate: PKC mu (Serine/threonine kinase)
Seq-ID: Q62101 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C activity,
metal ion binding,
ATP binding		 cytoplasm,
membrane		 protein amino acid phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 203 NCSGVRRRRLSNVSLTGLGTV PKD1 10867018
LTP
1.00
 - -
0.29
 - medium
S 744 FGFARIIGEKSFRRSVVGTPA PKD1 10867018
LTP
1.00
 - S_TKc
0.08
 - medium
S 744 FGFARIIGEKSFRRSVVGTPA PKD1 2407104
LTP
1.00
 - S_TKc
0.08
 - medium
S 748 RIIGEKSFRRSVVGTPAYLAP PKD1 10867018
LTP
1.00
 - S_TKc
0.12
 - medium
S 748 RIIGEKSFRRSVVGTPAYLAP PKD1 12407104
LTP
1.00
 - S_TKc
0.12
 - medium
S 916 REMKALSERVSIL         PKD1 10867018
LTP
0.00
 - -
0.24
 - medium
S 916 REMKALSERVSIL         PKD1 10473617
LTP
0.00
 - -
0.24
 - medium

Substrate: RIN1 (Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation)
Seq-ID: Q13671 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-13962   1433B_HUMAN
MINT-17571   1433Z_HUMAN
MINT-59456   ABL1_MOUSE
MINT-59459   ABL2_HUMAN
MINT-59464   RASH_HUMAN
MINT-59466   ABL1_HUMAN
MINT-74713   ERBB2_HUMAN
MINT-74714   ERBB3_HUMAN
MINT-7972262   DLG4_RAT
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
GTPase activator activity,
protein binding		 plasma membrane,
cytoplasm,
cytoskeleton		 signal transduction,
endocytosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 351 GRRRPLLRSMSAAFCSLLAPE PKD1 11784866
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.38
 - low

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