Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

Substrate:

Anaphase promoting complex subunit 1 (Cell cycle control protein)

Seq-ID:

Q9H1A4 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytosol, anaphase-promoting complex, nucleoplasm	cell division, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, mitosis, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	291	VVLKFSEQGGTPQNVATSSSL	PLK1	14657031	LTP	0.09		-	-	0.55	-	medium
S	355	SNMAALSRAHSPALGVHSFSG	PLK1	14657031	LTP	1.00		-	-	0.38	-	medium
S	377	QRFNISSHNQSPKRHSISHSP	PLK1	14657031	LTP	0.21	MOD_CDK_SPxK_1	-	-	0.67	-	medium
T	520	FIPGLPAPSLTMSNTMPRPST	PLK1	14657031	HTP	0.12		-	-	0.55	-	medium
T	530	TMSNTMPRPSTPLDGVSTPKP	PLK1	14657031	LTP	0.14		-	-	0.70	-	medium
S	686	AWTRNFDFEGSLSPVIAPKKA	PLK1	14657031	HTP	1.00	MOD_PLK	-	-	0.21	-	medium
S	688	TRNFDFEGSLSPVIAPKKARP	PLK1	14657031	LTP	0.27	MOD_PLK	-	-	0.27	-	medium

Substrate:

Anaphase promoting complex subunit 4 (Cell cycle control protein)

Seq-ID:

Q9UJX5 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ubiquitin-protein ligase activity	cytosol, anaphase-promoting complex, nucleoplasm	cell division, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, G2/M transition of mitotic cell cycle, mitotic anaphase

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	779	VKIKEEVLSESEAENQQAGAA	PLK1	14657031	HTP	0.29		-	-	0.59	-	medium

Substrate:

Anaphase promoting complex subunit 7 (Cell cycle control protein)

Seq-ID:

Q9UJX3 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytosol, anaphase-promoting complex, nucleoplasm	cell division, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, mitosis, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	17	VRDMAAAGLHSNVRLLSSLLL	PLK1	14657031	HTP	1.00	-	-	0.24	-	low
S	23	AGLHSNVRLLSSLLLTMSNNN	PLK1	14657031	HTP	0.30	-	-	0.31	-	low
S	30	RLLSSLLLTMSNNNPELFSPP	PLK1	14657031	HTP	1.00	-	-	0.37	-	low

Substrate:

APC8 (Cell cycle control protein)

Seq-ID:

Q9UJX2 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-66993 RBPMS_HUMAN
MINT-67439 T22D4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
binding, ubiquitin-protein ligase activity	cytosol, anaphase-promoting complex, nucleoplasm	cell division, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, G1 phase of mitotic cell cycle, protein K11-linked ubiquitination, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, mitotic metaphase/anaphase transition, regulation of exit from mitosis, mitotic metaphase plate congression, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, regulation of mitotic metaphase/anaphase transition

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	556	QILQLRNQGETPTTEVPAPFF	PLK1	14657031	LTP	0.00		-	-	0.39	-	medium

Substrate:

BRCA2 (Breast cancer type 2 susceptibility protein)

Seq-ID:

P51587 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-2791507   RD23A_HUMAN
MINT-4980796   RAD51_HUMAN
MINT-7243738   ABL1_HUMAN
MINT-7247350   FYN_HUMAN
MINT-7262197   PALB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription activator activity, protease binding, gamma-tubulin binding	centrosome, nucleoplasm, BRCA2-MAGE-D1 complex, stored secretory granule	regulation of S phase of mitotic cell cycle, response to estrogen stimulus, cell cycle cytokinesis, negative regulation of mammary gland epithelial cell proliferation, centrosome duplication, response to genistein, regulation of transcription, DNA-dependent, nucleotide-excision repair

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	193	SLGAEVDPDMSWSSSLATPPT	PLK1	12815053	LTP	1.00	MOD_PLK	-	-	0.56	-	medium

Substrate:

BUB1B (serine/threonine-protein kinase)

Seq-ID:

O60566 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7299818   CDC20_HUMAN
MINT-7299965   HDAC4_HUMAN
MINT-7299978   HDAC5_HUMAN
MINT-7300283   KAT2B_HUMAN
MINT-7300323   BUB3_HUMAN
MINT-7302173   HDAC1_HUMAN
MINT-7302197   HDAC2_HUMAN
MINT-7302235   HDAC3_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein binding	outer kinetochore of condensed chromosome, cytosol, anaphase-promoting complex, microtubule organizing center, spindle midzone	protein amino acid phosphorylation, cell division, apoptosis, phosphoinositide-mediated signaling, protein localization to kinetochore, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, mitosis, spindle organization, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell proliferation, mitotic cell cycle checkpoint

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	676	IKKLSPIIEDSREATHSSGFS	PLK1	17785528	LTP	1.00		-	-	0.46	-	medium

Substrate:

cdc25c (M-phase inducer phosphatase 3)

Seq-ID:

P30307 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16690 PLK1_HUMAN
MINT-3294433 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein tyrosine phosphatase activity, WW domain binding	cytosol, nucleoplasm	regulation of cyclin-dependent protein kinase activity, cell division, traversing start control point of mitotic cell cycle, protein amino acid dephosphorylation, regulation of mitosis, mitosis, interspecies interaction between organisms, DNA replication, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	198	EEISDELMEFSLKDQEAKVSR	PLK1	11897663	LTP	0.14	MOD_PLK	-	M-inducer_phosp	0.49	-	low

Substrate:

Cell division cycle protein 27 homolog (Cell cycle control protein)

Seq-ID:

P30260 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7244026   ABL1_HUMAN
MINT-7246846   FYN_HUMAN
MINT-7250398   NCK1_HUMAN
MINT-7251346   P85A_HUMAN
MINT-7974880   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	centrosome, spindle microtubule, cytosol, anaphase-promoting complex, nucleoplasm	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, mitotic metaphase/anaphase transition, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	209	ETVLTETPQDTIELNRLNLES	PLK1	14657031	HTP	0.08		-	-	0.59	-	medium
T	430	QPNINDSLEITKLDSSIISEG	PLK1	14657031	HTP	0.70		-	-	0.40	-	medium
S	434	NDSLEITKLDSSIISEGKIST	PLK1	14657031	HTP	0.28	MOD_PLK	-	-	0.35	-	medium
T	446	IISEGKISTITPQIQAFNLQK	PLK1	14657031	HTP	0.07		-	-	0.33	-	medium

Substrate:

CHK2 (Serine/threonine-protein kinase Chk2)

Seq-ID:

O96017 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13742   P53_HUMAN
MINT-15591   MPIP1_HUMAN
MINT-49652   NBN_HUMAN
MINT-58599   MDM2_HUMAN
MINT-62311   IMA2_HUMAN
MINT-4793727   RB_HUMAN
MINT-6806274   STRAP_HUMAN
MINT-7294980   XRCC1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, metal ion binding, ATP binding, protein binding	PML body	protein amino acid phosphorylation, senescence, cell cycle, DNA damage checkpoint, DNA damage response, signal transduction resulting in induction of apoptosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	26	SACSQPHGSVTQSQGSSSQSQ	PLK1	12493754	LTP	0.82	MOD_PIKK_1	-	-	0.79	-	-
T	68	GTLSSLETVSTQELYSIPEDQ	PLK1	12493754	LTP	0.08	MOD_PIKK_1	MDC1 FHA; PLK1 PBD	-	0.61	-	-

Substrate:

Cyclin B1 (Cell cycle control protein)

Seq-ID:

P14635 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-50660 CDN1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytosol, spindle pole, microtubule organizing center, outer kinetochore of condensed nuclear chromosome, nucleoplasm	cell division, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of mitotic cell cycle, mitotic prometaphase, positive regulation of attachment of spindle microtubules to kinetochore, mitotic cell cycle spindle checkpoint, mitotic metaphase plate congression, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, G2/M transition of mitotic cell cycle, mitotic spindle stabilization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	126	SPEPILVDTASPSPMETSGCA	PLK1	11242082	LTP	0.94	MOD_ProDKin_1	-	-	0.69	-	medium
S	126	SPEPILVDTASPSPMETSGCA	PLK1	12447691	LTP	0.94	MOD_ProDKin_1	-	-	0.69	-	medium
S	128	EPILVDTASPSPMETSGCAPA	PLK1	11242082	LTP	0.16	MOD_ProDKin_1	-	-	0.69	-	medium
S	128	EPILVDTASPSPMETSGCAPA	PLK1	12447691	LTP	0.16	MOD_ProDKin_1	-	-	0.69	-	medium
S	133	DTASPSPMETSGCAPAEEDLC	PLK1	11242082	LTP	1.00		-	-	0.67	-	medium
S	147	PAEEDLCQAFSDVILAVNDVD	PLK1	11242082	LTP	0.97		-	-	0.30	-	medium

Substrate:

HSF 1 (Transcription factor)

Seq-ID:

P38532 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity	cytoplasm, protein complex, pronucleus	protein amino acid phosphorylation, transcription, negative regulation of cell proliferation, negative regulation of tumor necrosis factor production, response to heat, embryonic process involved in female pregnancy, embryonic placenta development, positive regulation of multicellular organism growth, spermatogenesis, regulation of transcription, DNA-dependent, response to lipopolysaccharide

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	415	VDTSALLDLFSPSVTMPDMSL	PLK1	15661742	LTP	0.99		-	Vert_HS_TF	0.46	-	low

Substrate:

Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)

Seq-ID:

P35568 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19010   INSR_HUMAN
MINT-68735   P85A_HUMAN
MINT-74551   EGFR_HUMAN
MINT-74553   ERBB2_HUMAN
MINT-3975430   1433S_HUMAN
MINT-6628637   LT_SV40
MINT-6793745   PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoinositide 3-kinase binding, protein kinase C binding, insulin-like growth factor receptor binding, insulin receptor binding, transmembrane receptor protein tyrosine kinase docking protein activity, SH2 domain binding	microsome, caveola, cytosol, insulin receptor complex, nucleus	negative regulation of insulin receptor signaling pathway, glucose homeostasis, positive regulation of insulin receptor signaling pathway, positive regulation of fatty acid beta-oxidation, phosphoinositide 3-kinase cascade, negative regulation of insulin secretion, positive regulation of glycogen biosynthetic process, insulin receptor signaling pathway, positive regulation of glucose import, positive regulation of phosphoinositide 3-kinase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	24	RKVGYLRKPKSMHKRFFVLRA	PLK1	15849359	LTP	1.00		-	PH	0.26	1QQG	44.26%

Substrate:

KIAA0980 (calcium ion binding)

Seq-ID:

Q9Y2I6 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-64276   EZH2_HUMAN
MINT-64682   LRSM1_HUMAN
MINT-66256   ELOA1_HUMAN
MINT-66346   MD1L1_HUMAN
MINT-66601   SF17A_HUMAN
MINT-66630   UT14A_HUMAN
MINT-66821   GPKOW_HUMAN
MINT-66893   ZC3H1_HUMAN
MINT-66925   K1267_HUMAN
MINT-67232   ZFHX3_HUMAN
MINT-67724   MYST2_HUMAN
MINT-67741   RGS2_HUMAN
MINT-67778   CC130_HUMAN
MINT-67835   APEX2_HUMAN
MINT-67954   MCM10_HUMAN
MINT-68109   RCOR3_HUMAN
MINT-68225   MBIP1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding	cytosol, microtubule organizing center, microtubule

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	87	NAGVRPSDEDSSSLESAASSA	PLK1	12852856	LTP	0.96	-	-	0.70	-	low
S	88	AGVRPSDEDSSSLESAASSAI	PLK1	12852856	LTP	1.00	-	-	0.71	-	low
T	161	SPKSDEEAESTKEAQNELFEA	PLK1	12852856	LTP	0.00	-	-	0.76	-	low
S	686	KADLEELHEKSQEVIWGLQEQ	PLK1	12852856	LTP	0.14	-	COIL	0.46	-	low

Substrate:

Kinesin-like protein KIF23 (ATPase)

Seq-ID:

ENSMUSP00000034815 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
microtubule motor activity, ATP binding	microtubule	microtubule-based movement

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	904	ELPTGSRKRRSSTLAPAQPDG	PLK1	15199097	LTP	0.96		-	-	0.87	-	medium
S	905	LPTGSRKRRSSTLAPAQPDGT	PLK1	15199097	LTP	0.14		-	-	0.87	-	medium

Substrate:

Myt1 kinase (Kinase MYT1)

Seq-ID:

Q99640 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein binding	Golgi membrane, membrane fraction, nucleoplasm, endoplasmic reticulum membrane	protein amino acid phosphorylation, regulation of cyclin-dependent protein kinase activity, regulation of mitosis, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	426	SPPCSLLLDSSLSSNWDDDSL	PLK1	12738781	LTP	0.16	MOD_PLK	-	-	0.34	-	medium
T	495	PRNLLSLFEDTLDPT	PLK1	12738781	LTP	0.15	MOD_PLK	-	-	0.46	-	medium

Substrate:

NPM (nucleophosmin (nucleolar phosphoprotein B23) (from PhosphoBase))

Seq-ID:

P06748 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48882   M3K14_HUMAN
MINT-74886   P53_HUMAN
MINT-75016   PTBP1_HUMAN
MINT-75017   SFRS1_HUMAN
MINT-3089429   E2AK2_HUMAN
MINT-3296152   1433Z_HUMAN
MINT-4544864   AP2A_HUMAN
MINT-4544899   HDAC1_HUMAN
MINT-4544944   HDAC2_HUMAN
MINT-6541788   SENP3_HUMAN
MINT-7041169   HABP4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Tat protein binding, histone binding, ribosomal small subunit binding, protein heterodimerization activity, ribosomal large subunit binding, protein homodimerization activity, unfolded protein binding, transcription coactivator activity, NF-kappaB binding	spindle pole centrosome	response to stress, negative regulation of cell proliferation, negative regulation of centrosome duplication, nucleosome assembly, anti-apoptosis, cell aging, signal transduction, protein oligomerization, intracellular protein transport, centrosome cycle, interspecies interaction between organisms, positive regulation of NF-kappaB transcription factor activity, ribosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	4	MEDSMDMDMSPLRP	PLK1	15190079	LTP	1.00	MOD_PLK	-	-	0.63	-	-

Substrate:

Nuclear migration protein nudC (Nuclear distribution gene C (A.nidulans) homolog)

Seq-ID:

Q9Y266 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-48453 M3K3_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	nucleus, microtubule	cell division, mitosis, multicellular organismal development, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	274	INTKKINPENSKLSDLDSETR	PLK1	12852857	LTP	1.00		-	-	0.62	-	medium
S	326	FMDQHPEMDFSKAKFN	PLK1	12852857	LTP	0.99		-	-	0.49	-	medium

Substrate:

PIN1 (protein binding)

Seq-ID:

Q13526 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15316   TOP2A_HUMAN
MINT-15821   CSK21_HUMAN
MINT-19990   P53_HUMAN
MINT-63063   SOCS3_HUMAN
MINT-63769   LEPR_HUMAN
MINT-64243   MTFR1_HUMAN
MINT-64894   CHSS2_HUMAN
MINT-65416   DDX24_HUMAN
MINT-66285   T22D4_HUMAN
MINT-66396   RAI1_HUMAN
MINT-67692   HNRPC_HUMAN
MINT-67798   RBPMS_HUMAN
MINT-67901   RBBP8_HUMAN
MINT-2861778   UBQL4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoserine binding, phosphothreonine binding, peptidyl-prolyl cis-trans isomerase activity	nucleus	protein folding, negative regulation of transforming growth factor beta receptor signaling pathway, cell cycle, regulation of pathway-restricted SMAD protein phosphorylation, regulation of mitosis, positive regulation of ubiquitin-protein ligase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	65	VRCSHLLVKHSQSRRPSSWRQ	PLK1	16118204	LTP	0.07		-	Rotamase	0.48	1PIN	43.44%

Substrate:

Translationally controlled tumor protein (TCTP family)

Seq-ID:

P13693 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-2634433 AT1A1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, protein binding	extracellular space, multivesicular body	anti-apoptosis, cellular calcium ion homeostasis, calcium ion transport, response to virus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	46	VSRTEGNIDDSLIGGNASAEG	PLK1	12167714	LTP	0.81	MOD_PLK	-	TCTP	0.55	-	-
S	64	AEGPEGEGTESTVITGVDIVM	PLK1	12167714	LTP	0.34	MOD_PLK	-	TCTP	0.50	-	-

Substrate:

WEE 1 tyrosine kinase (Dual specificity kinase)

Seq-ID:

P30291 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50988   1433B_HUMAN
MINT-3295375   1433Z_HUMAN
MINT-3975741   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
magnesium ion binding, protein serine/threonine kinase activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, protein binding	nucleoplasm	protein amino acid phosphorylation, cell division, mitosis

Conservation:

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Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	53	EGSGHSTGEDSAFQEPDSPLP	PLK1	15070733	LTP	0.36	MOD_PLK	PLK1 PBD	-	0.96	-	medium
S	53	EGSGHSTGEDSAFQEPDSPLP	PLK1	16085715	LTP	0.36	MOD_PLK	PLK1 PBD	-	0.96	-	medium