Phospho.ELM Currently 19650 Instances in Phospho.ELM database.

List of substrates found:

CD79B  Leupaxin  Microtubule associated protein 2  Band 3 anion transport protein  CD79A  CD32  STAT 5  FCGR2C  PKC delta  SYK  BTK  FCGR2B  Vanilloid receptor like channel 2  LckBP1  PAG1  Epo-R  PLC gamma 2  Tyrosine-protein kinase Lyn  RGS16  NMT1  Casein kinase II, alpha chain  NIPP1  Protein disulfide-isomerase A3 precursor  CD150  CD19 

Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
B cell antigen receptor
Homo sapiens
Y196
SKAGMEEDHTYEGLDIDQTAT
Fyn;
Lyn
9531288
LTP
-
-
-
     
Y207
EGLDIDQTATYEDIVTLRTGE
Fyn;
Lyn
9531288
LTP
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
may assemble and regulate leukocyte signalling complexes 2
Mus musculus
Y72
YATNIQEPNVYSEVQEPKESV
Lyn
17640867
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cytoskeletal protein
Homo sapiens
Y67
AFGEHGSQGTYSNTKENGING
Fyn;
Lyn
15536091
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Anion exchange protein 1
Homo sapiens
Y8
MEELQDDYEDMMEENLEQ
Lyn;
Syk
10942405
LTP
-
-
-
-
     
Y21
MMEENLEQEEYEDPDIPESQM
Lyn;
Syk
10942405
LTP
-
-
-
-
     
Y359
SSPAKPDSSFYKGLDLNGGPD
Lyn;
Syk
10942405
LTP
-
-
-
-
     
Y904
TFDEEEGRDEYDEVAMPV
Lyn;
Syk
10942405
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
B cell antigen receptor
Homo sapiens
Y188
AGDEYEDENLYEGLNLDDCSM
Lyn
9531288
LTP
-
ITAM
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
CD antigen. Binds to the Fc region of immunoglobulins gamma.
Homo sapiens
Y281
KRQLEETNNDYETADGGYMTL
Fyn;
Lyn;
Syk;
BLK
8756631
LTP
-
-
-
-
     
Y288
NNDYETADGGYMTLNPRAPTD
Fyn;
Lyn;
Syk;
BLK
8756631
LTP
-
-
-
     
Y304
RAPTDDDKNIYLTLPPNDHVN
Fyn;
Lyn;
Syk;
BLK
8756631
LTP
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Transcription factor
Homo sapiens
Y694
TPVLAKAVDGYVKPQIKQVVP
Lyn;
Src;
JAK2
11641791
17081983
HTP/LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
transmembrane receptor activity
Homo sapiens
Y310
RAPTDDDKNIYLTLPPNDHVN
Lyn
8756631
LTP
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Protein kinase C, delta
Mus musculus
Y52
KTLVQKKPTMYPEWKTTFDAH
Lyn
7575560
15774464
LTP
-
-
-
-
     
Y155
RGAIKQAKIHYIKNHEFIATF
Lyn
10945993
7575560
15774464
LTP
-
-
-
-
     
Y565
FESIRVDTPHYPRWITKESKD
Lyn
7575560
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Spleen tyrosine kinase
Mus musculus
Y130
EDLKENLIREYVKQTWNLQGQ
Lyn;
Syk
9820500
LTP
-
-
-
1a81
     
Y317
RPESTVSFNPYEPTGGPWGPD
Lyn;
Syk
9857068
9820500
LTP
CBL SH2
-
-
-
     
Y342
REALPMDTEVYESPYADPEEI
Lyn;
Syk
8657103
9820500
LTP
PLCG_group SH2;
VAV1 SH2
-
-
-
     
Y346
PMDTEVYESPYADPEEIRPKE
Lyn;
Syk
8657103
9820500
LTP
PLCG_group SH2
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Bruton's tyrosine kinase
Homo sapiens
Y551
GLSRYVLDDEYTSSVGSKFPV
Lyn;
BTK
8630736
LTP
-
TyrKc
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
protein binding
Homo sapiens
-
Y292
DKVGAENTITYSLLMHPDALE
Lyn;
BLK
8756631
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Membrane transport protein
Homo sapiens
Y253
HIAIERRCKHYVELLVAQGAD
Lyn
12538589
LTP
-
Ank
-
-
             
Membrane transport protein
Mus musculus
Y253
HIAIERRCKHYVELLVAQGAD
Lyn
12538589
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Hematopoietic cell-specific LYN substrate 1
Homo sapiens
Y222
FNEMEAPTTAYKKTTPIEAAS
Lyn;
Fgr
10066823
LTP
-
-
-
-
     
Y378
PEPEPEPENDYEDVEEMDRHE
Lyn;
Syk
8578591
9104825
LTP
-
-
-
2hk5
     
Y397
HEQEDEPEGDYEEVLEPEDSS
Lyn;
Syk;
Fgr
8578591
9183008
9104825
LTP
-
-
-
2hk5
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Mus musculus
Y386
RRPSEEPEPDYEAIQTLNRED
Lyn
16920712
LTP
-
-
-
-
     
Y414
NGHHVPKESDYESIGDLQQCR
Lyn
16920712
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Receptor for erythropoietin, a major activator of erythropoiesis
Homo sapiens
Y368
PVGSEHAQDTYLVLDKWLLPR
Lyn;
JAK2
10579919
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Involved in transmembrane signaling
Homo sapiens
Y743
YPVTPELLERYNMERDINSLY
Fyn;
Lck;
Lyn
12181444
LTP
-
-
-
-
     
Y753
YNMERDINSLYDVSRMYVDPS
Fyn;
Lck;
Lyn;
Src;
BTK
11507089
11606584
12181444
15144186
HTP/LTP
-
-
-
-
     
Y759
INSLYDVSRMYVDPSEINPSM
Fyn;
Lck;
Lyn;
Src;
BTK
11507089
11606584
12181444
14656219
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Tyr protein kinase family
Mus musculus
-
Y397
GLARVIEDNEYTAREGAKFPI
Lyn
10415030
LTP
-
-
-
-
             
Tyr protein kinase family
Homo sapiens
Y397
GLARVIEDNEYTAREGAKFPI
Lyn
8530369
17081983
18088087
HTP/LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Regulator of G-protein signaling 16
Homo sapiens
Y177
SYPRFLKSPAYRDLAAQASAA
Lyn;
Src;
Src_group
11602604
12588871
LTP
-
RGS
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Unclassified
Homo sapiens
Y117
KTMEEASKRSYQFWDTQPVPK
Lyn
11594778
LTP
-
-
-
-
     
Y180
KELYTLLNENYVEDDDNMFRF
Fyn;
Lyn
11594778
LTP
-
NMT
-
1rxt
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
casein kinase II, alpha chain (CKII) (EC 2.7.1.37) (from PhosphoBase)
Homo sapiens
Y255
IAKVLGTEDLYDYIDKYNIEL
Lyn;
Fgr
12628006
LTP
-
S_TKc
-
1jwh
1na7
1pjk
1ymi
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
RNA binding protein
Homo sapiens
Y264
MQNFAFSGGLYGGLPPTHSEA
Lyn
11104670
LTP
-
-
-
-
     
Y335
EAVNEPKKKKYAKEAWPGKKP
Lyn
11104670
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Protein disulfide isomerase family
Rattus norvegicus
-
Y445
DATANDVPSPYEVKGFPTIYF
Lyn
8631326
LTP
-
-
-
-
     
Y454
PYEVKGFPTIYFSPANKKLTP
Lyn
8631326
LTP
-
-
-
-
     
Y467
PANKKLTPKKYEGGRELNDFI
Lyn
8631326
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
T cell antigen receptor
Homo sapiens
Y327
SVQETNSITVYASVTLPES
Fyn;
Lyn
11806999
15315965
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Antigen of human B-lymphocytes
Homo sapiens
Y500
REATSLGSQSYEDMRGILYAA
Lyn
9190913
10933394
LTP
PIK3R1 SH2
-
-
-
     
Y531
GPNHEEDADSYENMDNPDGPD
Lyn
9190913
10933394
LTP
PIK3R1 SH2
-
-
-