List of substrates found:

PDGF-R alpha  ZAP70  CBL E3 ubiquitin protein ligase  P130Cas  Paxillin  Gab1  SOCS3  Epo-R  CAS-L  Insulin R  Crk-like protein  Disabled homolog 1  STAT 5  p62DOK 


Substrate: PDGF-R alpha (Receptor tyrosine kinase)
Seq-ID: P16234 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 762 SKYSDIQRSLYDRPASYKKKS PDGFR_alpha 9546424
LTP
1.00
CRKL SH2;
CRK SH2
TyrKc
0.29
- medium
Y 762 SKYSDIQRSLYDRPASYKKKS - 18083107
HTP
1.00
CRKL SH2;
CRK SH2
TyrKc
0.29
- medium

Substrate: ZAP70 (Cytoplasmic tyrosine kinase)
Seq-ID: P43403 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 292 RRIDTLNSDGYTPEPARITSP Lck 8756661
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP ZAP70 8756661
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP Lck 7961936
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP ZAP70 7961936
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 15144186
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 15592455
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 16094384
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 15659558
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 17192257
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 11828374
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 7798261
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL - 12522270
HTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL - 15592455
HTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL - 16094384
HTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 10037717
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 319 PMDTSVYESPYSDPEELKDKK - 10202147
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 10318843
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 12522270
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15592455
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 16094384
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 10037717
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15268851
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15292262
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%

Substrate: CBL E3 ubiquitin protein ligase (Adaptor molecule)
Seq-ID: P22681 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 337 ALIDGFREGFYLFPDGRNQNP - 10608804
LTP
1.00
CRKL SH2;
CRK SH2;
PIK3R2 SH2
Cbl_N3
0.18
1YVH 9.61%
Y 674 IKPSSSANAIYSLAARPLPVP - 12522270
HTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 674 IKPSSSANAIYSLAARPLPVP - 15144186
HTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 674 IKPSSSANAIYSLAARPLPVP - 15592455
HTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 674 IKPSSSANAIYSLAARPLPVP - 15922744
LTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 700 EQCEGEEDTEYMTPSSRPLRP Fyn 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP SYK 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP Yes 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 9102067
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 12522270
HTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP INSR 11997497
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 10829062
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 15922744
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 731 DCDQQIDSCTYEAMYNIQSQA Fyn 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA SYK 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA Yes 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA - 10934191
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA Fyn 9890970
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA - 12604776
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA - 15922744
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 774 PEESENEDDGYDVPKPPVPAV Fyn 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV SYK 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV Yes 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 12522270
HTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 12604776
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 10829062
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 15922744
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--

Substrate: P130Cas (Adaptor molecule. Contain 15 YxxP motifs. )
Seq-ID: P56945 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 128 PTPSKAQQGLYQVPGPSPQFQ FGFR1 12601080
LTP
- CRKL SH2;
CRK SH2
-
0.76
- medium
Y 128 PTPSKAQQGLYQVPGPSPQFQ - 18083107
HTP
- CRKL SH2;
CRK SH2
-
0.76
- medium
Y 128 PTPSKAQQGLYQVPGPSPQFQ - 16212419
HTP
- CRKL SH2;
CRK SH2
-
0.76
- medium
Y 165 HPFPSPATDLYQVPPGPGGPA - 15817476
LTP
1.00
CRKL SH2;
CRK SH2
-
0.85
- medium
Y 234 YEAAQPEQDEYDIPRHLLAPG - 18083107
HTP
1.00
CRKL SH2;
CRK SH2
-
0.71
- medium
Y 234 YEAAQPEQDEYDIPRHLLAPG - 16212419
HTP
1.00
CRKL SH2;
CRK SH2
-
0.71
- medium
Y 249 HLLAPGPQDIYDVPPVRGLLP FGFR1 12601080
LTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.56
- medium
Y 249 HLLAPGPQDIYDVPPVRGLLP - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.56
- medium
Y 249 HLLAPGPQDIYDVPPVRGLLP - 16212419
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.56
- medium
Y 306 GLPPSNHHAVYDVPPSVSKDV FGFR1 12601080
LTP
0.94
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 327 PDGPLLREETYDVPPAFAKAK FGFR1 12601080
LTP
1.00
CRKL SH2;
CRK SH2
-
0.61
- medium
Y 387 GLRRPGPGTLYDVPRERVLPP - 15316024
LTP
0.02
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 387 GLRRPGPGTLYDVPRERVLPP - 18083107
HTP
0.02
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 387 GLRRPGPGTLYDVPRERVLPP - 16212419
HTP
0.02
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 410 ADGGVVDSGVYAVPPPAEREA FGFR1 12601080
LTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.72
- medium

Substrate: Paxillin (Cytoskeletal protein; component of focal adhesion.)
Seq-ID: P49023 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 31 RPVFLSEETPYSYPTGNHTYQ FAK 7537852
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 11774284
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 10823820
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 15107421
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 16254239
HTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 15817476
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ Brk 15572663
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ FAK 12408869
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE FAK 7537852
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 11774284
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE FAK 7615549
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 15592455
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 15107421
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 16254239
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 16094384
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 15817476
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE Brk 15572663
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 18083107
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 18669648
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low

Substrate: Gab1 (Multisubstrate docking protein downstream in the signaling pathways of different RTK.)
Seq-ID: Q13480 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 242 MNGFFQQQMIYDSPPSRAPSA INSR 10978177
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2
-
0.65
- low
Y 259 APSASVDSSLYNLPRSYSHDV - 12522270
HTP
0.15
CRKL SH2;
CRK SH2
-
0.59
- low
Y 307 ETQMRHVSISYDIPPTPGNTY Met 10734310
LTP
0.12
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2
-
0.70
- low
Y 307 ETQMRHVSISYDIPPTPGNTY EGFR 10734310
LTP
0.12
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2
-
0.70
- low
Y 317 YDIPPTPGNTYQIPRTFPEGT - 16497976
HTP
0.24
CRKL SH2;
CRK SH2;
PLCG1 SH2;
RASA_group SH2
-
0.74
- low
Y 373 PRTASDTDSSYCIPTAGMSPS INSR 10978177
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS EGFR 9890893
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS - 10753869
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS Met 10734310
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 406 LRKDASSQDCYDIPRAFPSDR EGFR 9890893
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR - 10753869
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR Met 10734310
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR - 18083107
HTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low

Substrate: SOCS3 (protein kinase inhibitor activity)
Seq-ID: O14543 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 221 PGPIREFLDQYDAPL       - 12783885
LTP
0.99
CRKL SH2;
NCK SH2;
RASA_group SH2
SOCS_box
0.43
--
Y 221 PGPIREFLDQYDAPL       Lck 15173187
LTP
0.99
CRKL SH2;
NCK SH2;
RASA_group SH2
SOCS_box
0.43
--

Substrate: Epo-R (Receptor for erythropoietin, a major activator of erythropoiesis)
Seq-ID: P19235 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
erythropoietin receptor activity extracellular region,
integral to plasma membrane
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 456 PPTPPHLKYLYLVVSDSGIST - 10579919
LTP
1.00
CISH SH2;
CRKL SH2;
INPP5D SH2;
PLCG2 SH2;
SOCS3 SH2;
STAT5 SH2
-
0.36
- low
Y 456 PPTPPHLKYLYLVVSDSGIST - 11443118
LTP
1.00
CISH SH2;
CRKL SH2;
INPP5D SH2;
PLCG2 SH2;
SOCS3 SH2;
STAT5 SH2
-
0.36
- low
Y 456 PPTPPHLKYLYLVVSDSGIST - 12027890
LTP
1.00
CISH SH2;
CRKL SH2;
INPP5D SH2;
PLCG2 SH2;
SOCS3 SH2;
STAT5 SH2
-
0.36
- low

Substrate: CAS-L (Docking protein)
Seq-ID: Q14511 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 166 TPVRTGHGYVYEYPSRYQKDV - 12522270
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2;
NCK SH2
-
0.43
- medium
Y 317 GQSVGSQNDAYDVPRGVQFLE - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2;
NCK SH2
-
0.70
- medium
Y 345 KANPQERDGVYDVPLHNPPDA - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2;
NCK SH2
-
0.86
- medium

Substrate: Insulin R (Receptor tyrosine kinase)
Seq-ID: P06213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 999 GPLYASSNPEYLSASDVFPCS INSR 8662806
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 1658004
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS - 8393870
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 10340378
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--

Substrate: Crk-like protein (Crk-like protein)
Seq-ID: P46109 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 207 SYGIPEPAHAYAQPQTTTPLP Abl 9710592
LTP
0.62
CRKL SH2 -
0.67
- low

Substrate: Disabled homolog 1 (Adapter molecule functioning in neural development)
Seq-ID: O75553 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 220 IRDPETEENIYQVPTSQKKEG - 15316068
LTP
0.93
CRKL SH2 -
0.70
- low
Y 232 VPTSQKKEGVYDVPKSQPVSN - 15316068
LTP
1.00
CRKL SH2 -
0.56
- low

Substrate: STAT 5 (Transcription factor)
Seq-ID: P42229 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 694 TPVLAKAVDGYVKPQIKQVVP Lyn 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP SRC 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP JAK2 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP - 17081983
HTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP - 18083107
HTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium

Substrate: p62DOK (Docking protein, common target of PTKs)
Seq-ID: Q99704 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 146 SALEMLENSLYSPTWEGSQFW - 11042170
LTP
1.00
CRKL SH2 -
0.21
--
Y 203 QILEPLLSWPYTLLRRYGRDK - 12087092
LTP
1.00
CRKL SH2;
INPP5D SH2
PTBI
0.17
2V76 5.24%
Y 296 QELLDSPPALYAEPLDSLRIA - 12087092
LTP
0.05
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 296 QELLDSPPALYAEPLDSLRIA - 10688886
LTP
0.05
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.66
--
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.66
--
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.66
--
Y 337 GEGVQRKKPLYWDLYEHAQQQ - 16497976
HTP
1.00
CRKL SH2;
PTPN11 SH2
-
0.48
--
Y 341 QRKKPLYWDLYEHAQQQLLKA - 12087092
LTP
0.23
CRKL SH2 -
0.41
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP INSR 11551902
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 15592455
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 16094384
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 15592455
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 16094384
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 398 WCQARVKEEGYELPYNPATDD - 12087092
LTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD INSR 11551902
LTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD - 10688886
LTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD - 15592455
HTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD - 16094384
HTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 402 RVKEEGYELPYNPATDDYAVP - 15592455
HTP
1.00
CRKL SH2 -
0.64
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 15592455
HTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 16094384
HTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 449 SGIKSHNSALYSQVQKSGASG - 12087092
LTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 10852966
LTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 12522270
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 15592455
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 16094384
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 15659558
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 18083107
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--


Valid HTML 4.01 Transitional