List of substrates found:

PDGF-R alpha  ZAP70  CBL E3 ubiquitin protein ligase  P130Cas  Paxillin  Gab1  SOCS3  Epo-R  CAS-L  Insulin R  Crk-like protein  Disabled homolog 1  STAT 5  p62DOK 


Substrate: PDGF-R alpha (Receptor tyrosine kinase)
Seq-ID: P16234 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 762 SKYSDIQRSLYDRPASYKKKS PDGFR_alpha 9546424
LTP
1.00
CRKL SH2;
CRK SH2
TyrKc
0.29
- medium
Y 762 SKYSDIQRSLYDRPASYKKKS - 18083107
HTP
1.00
CRKL SH2;
CRK SH2
TyrKc
0.29
- medium

Substrate: ZAP70 (Cytoplasmic tyrosine kinase)
Seq-ID: P43403 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 292 RRIDTLNSDGYTPEPARITSP Lck 8756661
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP ZAP70 8756661
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP Lck 7961936
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP ZAP70 7961936
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 15144186
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 15592455
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 16094384
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 15659558
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP - 17192257
HTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 11828374
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 7798261
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL - 12522270
HTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL - 15592455
HTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL - 16094384
HTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 10037717
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 319 PMDTSVYESPYSDPEELKDKK - 10202147
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 10318843
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 12522270
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15592455
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 16094384
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 10037717
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15268851
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15292262
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%

Substrate: CBL E3 ubiquitin protein ligase (Adaptor molecule)
Seq-ID: P22681 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 337 ALIDGFREGFYLFPDGRNQNP - 10608804
LTP
1.00
CRKL SH2;
CRK SH2;
PIK3R2 SH2
Cbl_N3
0.18
1YVH 9.61%
Y 674 IKPSSSANAIYSLAARPLPVP - 12522270
HTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 674 IKPSSSANAIYSLAARPLPVP - 15144186
HTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 674 IKPSSSANAIYSLAARPLPVP - 15592455
HTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 674 IKPSSSANAIYSLAARPLPVP - 15922744
LTP
0.25
CRKL SH2;
PLCG1 SH2
-
0.55
--
Y 700 EQCEGEEDTEYMTPSSRPLRP Fyn 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP SYK 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP Yes 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 9102067
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 12522270
HTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP INSR 11997497
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 10829062
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 700 EQCEGEEDTEYMTPSSRPLRP - 15922744
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 731 DCDQQIDSCTYEAMYNIQSQA Fyn 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA SYK 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA Yes 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA - 10934191
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA Fyn 9890970
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA - 12604776
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 731 DCDQQIDSCTYEAMYNIQSQA - 15922744
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 774 PEESENEDDGYDVPKPPVPAV Fyn 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV SYK 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV Yes 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 12522270
HTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 12604776
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 10829062
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--
Y 774 PEESENEDDGYDVPKPPVPAV - 15922744
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--

Substrate: P130Cas (Adaptor molecule. Contain 15 YxxP motifs. )
Seq-ID: P56945 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 128 PTPSKAQQGLYQVPGPSPQFQ FGFR1 12601080
LTP
- CRKL SH2;
CRK SH2
-
0.76
- medium
Y 128 PTPSKAQQGLYQVPGPSPQFQ - 18083107
HTP
- CRKL SH2;
CRK SH2
-
0.76
- medium
Y 128 PTPSKAQQGLYQVPGPSPQFQ - 16212419
HTP
- CRKL SH2;
CRK SH2
-
0.76
- medium
Y 165 HPFPSPATDLYQVPPGPGGPA - 15817476
LTP
1.00
CRKL SH2;
CRK SH2
-
0.85
- medium
Y 234 YEAAQPEQDEYDIPRHLLAPG - 18083107
HTP
1.00
CRKL SH2;
CRK SH2
-
0.71
- medium
Y 234 YEAAQPEQDEYDIPRHLLAPG - 16212419
HTP
1.00
CRKL SH2;
CRK SH2
-
0.71
- medium
Y 249 HLLAPGPQDIYDVPPVRGLLP FGFR1 12601080
LTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.56
- medium
Y 249 HLLAPGPQDIYDVPPVRGLLP - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.56
- medium
Y 249 HLLAPGPQDIYDVPPVRGLLP - 16212419
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.56
- medium
Y 306 GLPPSNHHAVYDVPPSVSKDV FGFR1 12601080
LTP
0.94
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 327 PDGPLLREETYDVPPAFAKAK FGFR1 12601080
LTP
1.00
CRKL SH2;
CRK SH2
-
0.61
- medium
Y 387 GLRRPGPGTLYDVPRERVLPP - 15316024
LTP
0.02
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 387 GLRRPGPGTLYDVPRERVLPP - 18083107
HTP
0.02
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 387 GLRRPGPGTLYDVPRERVLPP - 16212419
HTP
0.02
CRKL SH2;
CRK SH2
-
0.73
- medium
Y 410 ADGGVVDSGVYAVPPPAEREA FGFR1 12601080
LTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2
-
0.72
- medium

Substrate: Paxillin (Cytoskeletal protein; component of focal adhesion.)
Seq-ID: P49023 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 31 RPVFLSEETPYSYPTGNHTYQ FAK 7537852
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 11774284
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 10823820
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 15107421
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 16254239
HTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ - 15817476
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ Brk 15572663
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 31 RPVFLSEETPYSYPTGNHTYQ FAK 12408869
LTP
1.00
CRKL SH2;
CRK SH2
-
0.57
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE FAK 7537852
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 11774284
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE FAK 7615549
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 15592455
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 15107421
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 16254239
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 16094384
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 15817476
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE Brk 15572663
LTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 18083107
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low
Y 118 CSRVGEEEHVYSFPNKQKSAE - 18669648
HTP
0.93
CRKL SH2;
CRK SH2;
Csk SH2
Paxillin
0.73
- low

Substrate: Gab1 (Multisubstrate docking protein downstream in the signaling pathways of different RTK.)
Seq-ID: Q13480 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 242 MNGFFQQQMIYDSPPSRAPSA INSR 10978177
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2
-
0.65
- low
Y 259 APSASVDSSLYNLPRSYSHDV - 12522270
HTP
0.15
CRKL SH2;
CRK SH2
-
0.59
- low
Y 307 ETQMRHVSISYDIPPTPGNTY Met 10734310
LTP
0.12
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2
-
0.70
- low
Y 307 ETQMRHVSISYDIPPTPGNTY EGFR 10734310
LTP
0.12
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2
-
0.70
- low
Y 317 YDIPPTPGNTYQIPRTFPEGT - 16497976
HTP
0.24
CRKL SH2;
CRK SH2;
PLCG1 SH2;
RASA_group SH2
-
0.74
- low
Y 373 PRTASDTDSSYCIPTAGMSPS INSR 10978177
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS EGFR 9890893
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS - 10753869
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS Met 10734310
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 406 LRKDASSQDCYDIPRAFPSDR EGFR 9890893
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR - 10753869
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR Met 10734310
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR - 18083107
HTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low

Substrate: SOCS3 (protein kinase inhibitor activity)
Seq-ID: O14543 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 221 PGPIREFLDQYDAPL       - 12783885
LTP
0.99
CRKL SH2;
NCK SH2;
RASA_group SH2
SOCS_box
0.43
--
Y 221 PGPIREFLDQYDAPL       Lck 15173187
LTP
0.99
CRKL SH2;
NCK SH2;
RASA_group SH2
SOCS_box
0.43
--

Substrate: Epo-R (Receptor for erythropoietin, a major activator of erythropoiesis)
Seq-ID: P19235 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
erythropoietin receptor activity extracellular region,
integral to plasma membrane
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 456 PPTPPHLKYLYLVVSDSGIST - 10579919
LTP
1.00
CISH SH2;
CRKL SH2;
INPP5D SH2;
PLCG2 SH2;
SOCS3 SH2;
STAT5 SH2
-
0.36
- low
Y 456 PPTPPHLKYLYLVVSDSGIST - 11443118
LTP
1.00
CISH SH2;
CRKL SH2;
INPP5D SH2;
PLCG2 SH2;
SOCS3 SH2;
STAT5 SH2
-
0.36
- low
Y 456 PPTPPHLKYLYLVVSDSGIST - 12027890
LTP
1.00
CISH SH2;
CRKL SH2;
INPP5D SH2;
PLCG2 SH2;
SOCS3 SH2;
STAT5 SH2
-
0.36
- low

Substrate: CAS-L (Docking protein)
Seq-ID: Q14511 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 166 TPVRTGHGYVYEYPSRYQKDV - 12522270
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2;
NCK SH2
-
0.43
- medium
Y 317 GQSVGSQNDAYDVPRGVQFLE - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2;
NCK SH2
-
0.70
- medium
Y 345 KANPQERDGVYDVPLHNPPDA - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
CRK SH2;
NCK SH2
-
0.86
- medium

Substrate: Insulin R (Receptor tyrosine kinase)
Seq-ID: P06213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 999 GPLYASSNPEYLSASDVFPCS INSR 8662806
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 1658004
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS - 8393870
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 10340378
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--

Substrate: Crk-like protein (Crk-like protein)
Seq-ID: P46109 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 207 SYGIPEPAHAYAQPQTTTPLP Abl 9710592
LTP
0.62
CRKL SH2 -
0.67
- low

Substrate: Disabled homolog 1 (Adapter molecule functioning in neural development)
Seq-ID: O75553 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 220 IRDPETEENIYQVPTSQKKEG - 15316068
LTP
0.93
CRKL SH2 -
0.70
- low
Y 232 VPTSQKKEGVYDVPKSQPVSN - 15316068
LTP
1.00
CRKL SH2 -
0.56
- low

Substrate: STAT 5 (Transcription factor)
Seq-ID: P42229 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 694 TPVLAKAVDGYVKPQIKQVVP Lyn 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP SRC 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP JAK2 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP - 17081983
HTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium
Y 694 TPVLAKAVDGYVKPQIKQVVP - 18083107
HTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium

Substrate: p62DOK (Docking protein, common target of PTKs)
Seq-ID: Q99704 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 146 SALEMLENSLYSPTWEGSQFW - 11042170
LTP
1.00
CRKL SH2 -
0.21
--
Y 203 QILEPLLSWPYTLLRRYGRDK - 12087092
LTP
1.00
CRKL SH2;
INPP5D SH2
PTBI
0.17
2V76 5.24%
Y 296 QELLDSPPALYAEPLDSLRIA - 12087092
LTP
0.05
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 296 QELLDSPPALYAEPLDSLRIA - 10688886
LTP
0.05
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.66
--
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.66
--
Y 315 IAPCPSQDSLYSDPLDSTSAQ - 18083107
HTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.66
--
Y 337 GEGVQRKKPLYWDLYEHAQQQ - 16497976
HTP
1.00
CRKL SH2;
PTPN11 SH2
-
0.48
--
Y 341 QRKKPLYWDLYEHAQQQLLKA - 12087092
LTP
0.23
CRKL SH2 -
0.41
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP INSR 11551902
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 15592455
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 362 KLTDPKEDPIYDEPEGLAPVP - 16094384
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
NCK SH2;
RASA_group SH2
-
0.82
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 15592455
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 377 GLAPVPPQGLYDLPREPKDAW - 16094384
HTP
1.00
ABL1 SH2;
CRKL SH2;
INPP5D SH2;
RASA_group SH2
-
0.62
--
Y 398 WCQARVKEEGYELPYNPATDD - 12087092
LTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD INSR 11551902
LTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD - 10688886
LTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD - 15592455
HTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 398 WCQARVKEEGYELPYNPATDD - 16094384
HTP
0.17
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.48
--
Y 402 RVKEEGYELPYNPATDDYAVP - 15592455
HTP
1.00
CRKL SH2 -
0.64
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 12087092
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 10688886
LTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 15592455
HTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 409 ELPYNPATDDYAVPPPRSTKP - 16094384
HTP
1.00
ABL1 SH2;
CRKL SH2;
RASA_group SH2
-
0.72
--
Y 449 SGIKSHNSALYSQVQKSGASG - 12087092
LTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 10852966
LTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 12522270
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 15592455
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 16094384
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 15659558
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--
Y 449 SGIKSHNSALYSQVQKSGASG - 18083107
HTP
0.00
CRKL SH2;
SH2D1A SH2
-
0.59
--


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