Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

VEGFR-1 VEGFR-2 ZAP70 SH3 domain-binding protein 2 c-met SYK LAT TRKB

Substrate: VEGFR-1 (Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity.)

Seq-ID: P17948 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-6177086   LDLR_HUMAN
MINT-6539646   CBL_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

vascular endothelial growth factor receptor activity,
ATP binding,
growth factor binding cytoplasm,
integral to plasma membrane,
extracellular space positive regulation of vascular endothelial growth factor receptor signaling pathway,
female pregnancy,
peptidyl-tyrosine phosphorylation,
cell differentiation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 794 KRSSSEIKTDYLSIIMDPDEV - 11741094
LTP

0.97
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2 -
0.30
- low

Y 794 KRSSSEIKTDYLSIIMDPDEV - 9398617
LTP

0.97
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2 -
0.30
- low

Y 1169 QANVQQDGKDYIPINAILTGN - 11513746
LTP

1.00
PIK3R1 SH2;
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2 -
0.30
- low

Y 1169 QANVQQDGKDYIPINAILTGN - 9299537
LTP

1.00
PIK3R1 SH2;
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2 -
0.30
- low

Y 1333 PPPDYNSVVLYSTPPI      FLT1 11513746
LTP

0.46
CRK SH2;
NCK SH2;
PLCG_group SH2 -
0.37
- low

Y 1333 PPPDYNSVVLYSTPPI      FLT1 9722576
LTP

0.46
CRK SH2;
NCK SH2;
PLCG_group SH2 -
0.37
- low

Y 1333 PPPDYNSVVLYSTPPI      - 9600074
LTP

0.46
CRK SH2;
NCK SH2;
PLCG_group SH2 -
0.37
- low

Substrate: VEGFR-2 (Receptor tyrosine kinase)

Seq-ID: P35968 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-49634   CADH5_HUMAN
MINT-49637   SHC1_HUMAN
MINT-2834292   NRP1_HUMAN
MINT-3381238   GRB2_HUMAN
MINT-3381278   NCK1_HUMAN
MINT-3381335   FYN_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

Hsp90 protein binding,
vascular endothelial growth factor receptor activity,
receptor signaling protein tyrosine kinase activity,
ATP binding,
growth factor binding,
integrin binding integral to plasma membrane positive regulation of positive chemotaxis,
protein amino acid phosphorylation,
positive regulation of endothelial cell proliferation,
angiogenesis,
regulation of cell shape,
interspecies interaction between organisms,
positive regulation of endothelial cell migration,
positive regulation of focal adhesion assembly

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 801 RANGGELKTGYLSIVMDPDEL - 11741094
LTP

1.00
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2 -
0.23
- -

Y 1175 QANAQQDGKDYIVLPISETLS KDR 10579917
LTP

1.00
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2 -
0.41
- -

Y 1175 QANAQQDGKDYIVLPISETLS KDR 11387210
LTP

1.00
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2 -
0.41
- -

Y 1175 QANAQQDGKDYIVLPISETLS - 10749680
LTP

1.00
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2 -
0.41
- -

Y 1175 QANAQQDGKDYIVLPISETLS - 14532277
LTP

1.00
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2 -
0.41
- -

Substrate: ZAP70 (Cytoplasmic tyrosine kinase)

Seq-ID: P43403 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-59476   LCK_HUMAN
MINT-60980   SHC1_HUMAN
MINT-74806   ERBB3_HUMAN
MINT-74807   EGFR_HUMAN
MINT-3374106   HS90A_HUMAN
MINT-3382488   LAT_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

non-membrane spanning protein tyrosine kinase activity,
ATP binding cytosol,
T cell receptor complex positive thymic T cell selection,
immune response,
intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 11828374
LTP

1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2 -
0.69
2OZO 6.42%

Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 7798261
LTP

1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2 -
0.69
2OZO 6.42%

Y 315 PRPMPMDTSVYESPYSDPEEL - 12522270
HTP

1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2 -
0.69
2OZO 6.42%

Y 315 PRPMPMDTSVYESPYSDPEEL - 15592455
HTP

1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2 -
0.69
2OZO 6.42%

Y 315 PRPMPMDTSVYESPYSDPEEL - 16094384
HTP

1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2 -
0.69
2OZO 6.42%

Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 10037717
LTP

1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2 -
0.69
2OZO 6.42%

Y 319 PMDTSVYESPYSDPEELKDKK - 10202147
LTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 10318843
LTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 12522270
HTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 15592455
HTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 16094384
HTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 10037717
LTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 15268851
LTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Y 319 PMDTSVYESPYSDPEELKDKK - 15292262
LTP

1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2 -
0.52
2OZO 1.83%

Substrate: SH3 domain-binding protein 2 (Adaptor molecule)

Seq-ID: P78314 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-17097   1433T_HUMAN
MINT-74724   ERBB2_HUMAN
MINT-4549720   VAV_HUMAN
MINT-4563345   DBNL_HUMAN
MINT-4563367   SH3K1_HUMAN
MINT-7301276   VAV2_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

SH3 domain binding,
SH3/SH2 adaptor activity

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 183 DYEHDDEDDSYLEPDSPEPGR - 11390470
LTP

1.00
PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV2 SH2;
VAV_group SH2 -
0.89
- medium

Substrate: c-met (Receptor tyrosine kinase for hepatocyte growth factor.)

Seq-ID: P08581 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-18299   RANB9_HUMAN
MINT-58374   GAB1_MOUSE
MINT-58404   GAB1_HUMAN
MINT-6539587   CBL_HUMAN
MINT-6787689   PTN1_HUMAN
MINT-6798640   PTN11_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

hepatocyte growth factor receptor activity,
ATP binding,
protein binding integral to plasma membrane,
basal plasma membrane protein amino acid phosphorylation,
multicellular organismal development,
cell proliferation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 1349 AIFSTFIGEHYVHVNATYVNV Met 12475979
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1349 AIFSTFIGEHYVHVNATYVNV - 9444958
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1349 AIFSTFIGEHYVHVNATYVNV - 9252406
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1349 AIFSTFIGEHYVHVNATYVNV - 7513258
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7731718
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7687741
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1349 AIFSTFIGEHYVHVNATYVNV - 9826708
LTP

1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.03
3F66 100.00%

Y 1356 GEHYVHVNATYVNVKCVAPYP - 12475979
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP - 9444958
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP - 9252406
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP - 7513258
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7731718
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP - 8662889
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7961992
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7687741
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Y 1356 GEHYVHVNATYVNVKCVAPYP - 9826708
LTP

1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2 -
0.06
1R0P 15.72%

Substrate: SYK (Spleen tyrosine kinase )

Seq-ID: P48025 [Mus musculus]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
MINT-56734   P85A_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

receptor signaling protein tyrosine kinase activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding B cell receptor complex,
cytoplasm positive regulation of peptidyl-tyrosine phosphorylation,
positive regulation of interleukin-3 biosynthetic process,
B cell receptor signaling pathway,
serotonin secretion,
positive regulation of alpha-beta T cell proliferation,
positive regulation of calcium-mediated signaling,
positive regulation of B cell differentiation,
activation of JUN kinase activity,
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process,
beta selection,
positive regulation of gamma-delta T cell differentiation,
positive regulation of mast cell degranulation,
leukotriene biosynthetic process,
protein amino acid autophosphorylation,
enzyme linked receptor protein signaling pathway,
peptidyl-tyrosine phosphorylation,
positive regulation of alpha-beta T cell differentiation,
G-protein coupled receptor protein signaling pathway

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 342 REALPMDTEVYESPYADPEEI SYK 8657103
LTP

1.00
PLCG_group SH2;
VAV1 SH2 -
0.58
- -

Y 342 REALPMDTEVYESPYADPEEI Lyn 9820500
LTP

1.00
PLCG_group SH2;
VAV1 SH2 -
0.58
- -

Y 346 PMDTEVYESPYADPEEIRPKE SYK 8657103
LTP

1.00
PLCG_group SH2 -
0.54
- -

Y 346 PMDTEVYESPYADPEEIRPKE Lyn 9820500
LTP

1.00
PLCG_group SH2 -
0.54
- -

Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)

Seq-ID: O54957 [Mus musculus]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

SH3/SH2 adaptor activity,
receptor signaling protein activity integral to plasma membrane,
immunological synapse calcium-mediated signaling,
integrin-mediated signaling pathway,
gene expression,
cellular defense response,
inflammatory response,
mast cell degranulation,
regulation of T cell activation,
Ras protein signal transduction,
transmembrane receptor protein tyrosine kinase signaling pathway

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 136 DEDEDDYPNGYLVVLPDSSPA - 10811803
LTP

0.00
PLCG_group SH2 -
0.77
- low

Y 136 DEDEDDYPNGYLVVLPDSSPA ZAP70 11368773
LTP

0.00
PLCG_group SH2 -
0.77
- low

Y 136 DEDEDDYPNGYLVVLPDSSPA ZAP70 11457888
LTP

0.00
PLCG_group SH2 -
0.77
- low

Substrate: TRKB (Receptor for brain-derived neurothrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5.)

Seq-ID: P15209 [Mus musculus]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

transmembrane receptor protein tyrosine kinase activity,
ATP binding cytosol,
integral to plasma membrane,
terminal button regulation of metabolic process,
feeding behavior,
vasculogenesis,
glutamate secretion,
mechanoreceptor differentiation,
retinal rod cell development

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 816 LQNLAKASPVYLDILG      TRKB 8106527
LTP

1.00
PLCG_group SH2 -
0.07
- medium

Y 816 LQNLAKASPVYLDILG      TRKB 9582017
LTP

1.00
PLCG_group SH2 -
0.07
- medium

Y 816 LQNLAKASPVYLDILG      TRKB 10533983
LTP

1.00
PLCG_group SH2 -
0.07
- medium

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	794	KRSSSEIKTDYLSIIMDPDEV	-	11741094	LTP	0.97	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2	-	0.30	-	low
Y	794	KRSSSEIKTDYLSIIMDPDEV	-	9398617	LTP	0.97	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2	-	0.30	-	low
Y	1169	QANVQQDGKDYIPINAILTGN	-	11513746	LTP	1.00	PIK3R1 SH2; PLCG1 SH2; PLCG2 SH2; PLCG_group SH2	-	0.30	-	low
Y	1169	QANVQQDGKDYIPINAILTGN	-	9299537	LTP	1.00	PIK3R1 SH2; PLCG1 SH2; PLCG2 SH2; PLCG_group SH2	-	0.30	-	low
Y	1333	PPPDYNSVVLYSTPPI	FLT1	11513746	LTP	0.46	CRK SH2; NCK SH2; PLCG_group SH2	-	0.37	-	low
Y	1333	PPPDYNSVVLYSTPPI	FLT1	9722576	LTP	0.46	CRK SH2; NCK SH2; PLCG_group SH2	-	0.37	-	low
Y	1333	PPPDYNSVVLYSTPPI	-	9600074	LTP	0.46	CRK SH2; NCK SH2; PLCG_group SH2	-	0.37	-	low

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	801	RANGGELKTGYLSIVMDPDEL	-	11741094	LTP	1.00	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2	-	0.23	-	-
Y	1175	QANAQQDGKDYIVLPISETLS	KDR	10579917	LTP	1.00	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2; SHB SH2; SHC2 SH2	-	0.41	-	-
Y	1175	QANAQQDGKDYIVLPISETLS	KDR	11387210	LTP	1.00	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2; SHB SH2; SHC2 SH2	-	0.41	-	-
Y	1175	QANAQQDGKDYIVLPISETLS	-	10749680	LTP	1.00	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2; SHB SH2; SHC2 SH2	-	0.41	-	-
Y	1175	QANAQQDGKDYIVLPISETLS	-	14532277	LTP	1.00	PLCG1 SH2; PLCG2 SH2; PLCG_group SH2; SHB SH2; SHC2 SH2	-	0.41	-	-

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	315	PRPMPMDTSVYESPYSDPEEL	ZAP70	11828374	LTP	1.00	CRKL SH2; CRK SH2; PLCG1 SH2; PLCG_group SH2; VAV1 SH2; VAV_group SH2	-	0.69	2OZO	6.42%
Y	315	PRPMPMDTSVYESPYSDPEEL	ZAP70	7798261	LTP	1.00	CRKL SH2; CRK SH2; PLCG1 SH2; PLCG_group SH2; VAV1 SH2; VAV_group SH2	-	0.69	2OZO	6.42%
Y	315	PRPMPMDTSVYESPYSDPEEL	-	12522270	HTP	1.00	CRKL SH2; CRK SH2; PLCG1 SH2; PLCG_group SH2; VAV1 SH2; VAV_group SH2	-	0.69	2OZO	6.42%
Y	315	PRPMPMDTSVYESPYSDPEEL	-	15592455	HTP	1.00	CRKL SH2; CRK SH2; PLCG1 SH2; PLCG_group SH2; VAV1 SH2; VAV_group SH2	-	0.69	2OZO	6.42%
Y	315	PRPMPMDTSVYESPYSDPEEL	-	16094384	HTP	1.00	CRKL SH2; CRK SH2; PLCG1 SH2; PLCG_group SH2; VAV1 SH2; VAV_group SH2	-	0.69	2OZO	6.42%
Y	315	PRPMPMDTSVYESPYSDPEEL	ZAP70	10037717	LTP	1.00	CRKL SH2; CRK SH2; PLCG1 SH2; PLCG_group SH2; VAV1 SH2; VAV_group SH2	-	0.69	2OZO	6.42%
Y	319	PMDTSVYESPYSDPEELKDKK	-	10202147	LTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	10318843	LTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	12522270	HTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	15592455	HTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	16094384	HTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	10037717	LTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	15268851	LTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%
Y	319	PMDTSVYESPYSDPEELKDKK	-	15292262	LTP	1.00	CRKL SH2; CRK SH2; Lck SH2; PLCG1 SH2; PLCG_group SH2	-	0.52	2OZO	1.83%

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1349	AIFSTFIGEHYVHVNATYVNV	Met	12475979	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1349	AIFSTFIGEHYVHVNATYVNV	-	9444958	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1349	AIFSTFIGEHYVHVNATYVNV	-	9252406	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1349	AIFSTFIGEHYVHVNATYVNV	-	7513258	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1349	AIFSTFIGEHYVHVNATYVNV	Met	7731718	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1349	AIFSTFIGEHYVHVNATYVNV	Met	7687741	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1349	AIFSTFIGEHYVHVNATYVNV	-	9826708	LTP	1.00	GRB2 SH2; Lck SH2; PIK3R1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.03	3F66	100.00%
Y	1356	GEHYVHVNATYVNVKCVAPYP	-	12475979	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	-	9444958	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	-	9252406	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	-	7513258	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	Met	7731718	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	-	8662889	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	Met	7961992	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	Met	7687741	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%
Y	1356	GEHYVHVNATYVNVKCVAPYP	-	9826708	LTP	1.00	GRB2 SH2; INPP5D SH2; INPPL1 SH2; PIK3R1 SH2; PLCG1 SH2; PLCG_group SH2; SHC_group SH2; Src SH2	-	0.06	1R0P	15.72%

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	342	REALPMDTEVYESPYADPEEI	SYK	8657103	LTP	1.00	PLCG_group SH2; VAV1 SH2	-	0.58	-	-
Y	342	REALPMDTEVYESPYADPEEI	Lyn	9820500	LTP	1.00	PLCG_group SH2; VAV1 SH2	-	0.58	-	-
Y	346	PMDTEVYESPYADPEEIRPKE	SYK	8657103	LTP	1.00	PLCG_group SH2	-	0.54	-	-
Y	346	PMDTEVYESPYADPEEIRPKE	Lyn	9820500	LTP	1.00	PLCG_group SH2	-	0.54	-	-

Res.	Pos.	Sequence	Kinase	PMID	Src	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	136	DEDEDDYPNGYLVVLPDSSPA	-	10811803	LTP	PLCG_group SH2	-	0.77	-	low
Y	136	DEDEDDYPNGYLVVLPDSSPA	ZAP70	11368773	LTP	PLCG_group SH2	-	0.77	-	low
Y	136	DEDEDDYPNGYLVVLPDSSPA	ZAP70	11457888	LTP	PLCG_group SH2	-	0.77	-	low

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	816	LQNLAKASPVYLDILG	TRKB	8106527	LTP	1.00	PLCG_group SH2	-	0.07	-	medium
Y	816	LQNLAKASPVYLDILG	TRKB	9582017	LTP	1.00	PLCG_group SH2	-	0.07	-	medium
Y	816	LQNLAKASPVYLDILG	TRKB	10533983	LTP	1.00	PLCG_group SH2	-	0.07	-	medium