Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

14-3-3 tau
14-3-3 zeta/delta
Alpha-S1 casein precursor
Alpha-S2 casein precursor
APC
Beta casein precursor
Beta-catenin
BID
Casein kinase I, epsilon
CDK5
Galectin-3
glycogen synthase
IPP2
NFAT4
p53
Presenilin 2
Synaptic vesicular amine transporter

Substrate:

14-3-3 tau (14-3-3 protein tau (14-3-3 protein theta) (HS1 protein) (from PhosphoBase))

Seq-ID:

P27348 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14051   TSC2_HUMAN
MINT-16257   PK3CB_HUMAN
MINT-16333   PDPK1_HUMAN
MINT-17097   3BP2_HUMAN
MINT-17889   CDN1B_HUMAN
MINT-18935   YAP1_HUMAN
MINT-48421   M3K3_HUMAN
MINT-50360   KLC2_HUMAN
MINT-50361   PI4KB_HUMAN
MINT-50362   MEP50_HUMAN
MINT-50363   HSP71_HUMAN
MINT-50365   K1C9_HUMAN
MINT-50370   KINH_HUMAN
MINT-50371   UBP8_HUMAN
MINT-50372   BRAF_HUMAN
MINT-50373   HSP7C_HUMAN
MINT-50375   IF4A3_HUMAN
MINT-51000   LARP1_HUMAN
MINT-51002   RAI14_HUMAN
MINT-51003   MPRIP_HUMAN
MINT-51004   Q8IXP7_HUMAN
MINT-62137   SMAD9_HUMAN
MINT-2868973   UBQL4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein domain specific binding, protein N-terminus binding	cytoplasm	negative regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	232	RDNLTLWTSDSAGEECDAAEG	CK1_group	16045749	LTP	0.09	-	14_3_3	0.42	-	-
S	232	RDNLTLWTSDSAGEECDAAEG	CK1_group	9360956	LTP	0.09	-	14_3_3	0.42	-	-
S	232	RDNLTLWTSDSAGEECDAAEG	CK1_group	9360956	LTP	0.09	-	14_3_3	0.42	-	-

Substrate:

14-3-3 zeta/delta (14-3-3 protein zeta/delta (Protein kinase C inhibitor protein-1) (KCIP-1) (Factor activating exoenzyme S) (FAS))

Seq-ID:

P29361 [Ovis aries]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein domain specific binding	melanosome

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	232	RDNLTLWTSDTQGDEAEAGEG	CK1_group	9360956	LTP	0.10		-	14_3_3	0.61	-	-

Substrate:

Alpha-S1 casein precursor (alpha-S1 casein (from PhosphoBase))

Seq-ID:

P02662 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
antioxidant activity, transporter activity	extracellular region

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	56	VFGKEKVNELSKDIGSESTED	CK1_group	6814825	LTP	0.03		-	-	0.56	-	medium

Substrate:

Alpha-S2 casein precursor (alpha-S2 casein (from PhosphoBase))

Seq-ID:

P02663 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transporter activity	extracellular region	defense response to bacterium

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	24	LAKNTMEHVSSSEESIISQET	CK1_group	6814825	LTP	1.00		-	-	0.43	-	medium
S	25	AKNTMEHVSSSEESIISQETY	CK1_group	6814825	LTP	1.00	MOD_CK1_1	-	-	0.45	-	medium
S	28	TMEHVSSSEESIISQETYKQE	CK1_group	6814825	LTP	0.97	MOD_CK1_1	-	-	0.49	-	medium
S	31	HVSSSEESIISQETYKQEKNM	CK1_group	6814825	LTP	0.00	MOD_CK1_1	-	-	0.47	-	medium
S	146	PTLNREQLSTSEENSKKTVDM	CK1_group	6814825	LTP	1.00	MOD_CK2_1	-	Casein	0.66	-	medium
S	150	REQLSTSEENSKKTVDMESTE	CK1_group	6814825	LTP	0.05	MOD_CK1_1	-	Casein	0.61	-	medium

Substrate:

APC (Adhesion molecule)

Seq-ID:

P25054 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1780719   DLG4_MOUSE
MINT-3296068   1433Z_HUMAN
MINT-3975353   1433S_HUMAN
MINT-4508229   CTNB1_HUMAN
MINT-6732416   SCRIB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
microtubule plus-end binding, protein kinase regulator activity, protein kinase binding, beta-catenin binding, gamma-catenin binding	centrosome, Axin-APC-beta-catenin-GSK3B complex, beta-catenin destruction complex, cytosol, lateral plasma membrane, kinetochore, adherens junction, nucleus, tight junction	negative regulation of cyclin-dependent protein kinase activity, positive regulation of protein catabolic process, protein complex assembly, positive regulation of cell migration, positive regulation of pseudopodium assembly, cell cycle arrest, cytokinesis after mitosis, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of apoptosis, canonical Wnt receptor signaling pathway, negative regulation of microtubule depolymerization, regulation of attachment of spindle microtubules to kinetochore, response to DNA damage stimulus, cell adhesion, tight junction assembly, mitotic cell cycle spindle assembly checkpoint

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1279	ICFSRCSSLSSLSSAEDEIGC	CK1_group	11487578	LTP	1.00	MOD_CK1_1	-	APC_crr	0.37	-	medium
S	1392	LMFSRCTSVSSLDSFESRSIA	CK1_group	11487578	LTP	1.00	MOD_CK1_1	-	APC_crr	0.48	-	medium

Substrate:

Beta casein precursor (beta casein (from PhosphoBase))

Seq-ID:

P02666 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
antioxidant activity, transporter activity, metalloendopeptidase inhibitor activity	extracellular region	regulation of blood pressure

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	33	VPGEIVESLSSSEESITRINK	CK1_group	6814825	LTP	1.00	MOD_CK1_1	-	COIL	0.44	-	low
S	34	PGEIVESLSSSEESITRINKK	CK1_group	6814825	LTP	1.00	MOD_CK1_1	-	COIL	0.43	-	low
S	37	IVESLSSSEESITRINKKIEK	CK1_group	6814825	LTP	1.00	MOD_CK1_1	-	COIL	0.43	-	low

Substrate:

Beta-catenin (Adhesion molecule)

Seq-ID:

P35222 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-46005   CADH1_HUMAN
MINT-46006   CTNA1_HUMAN
MINT-49803   ANDR_HUMAN
MINT-49805   NCOA2_HUMAN
MINT-1779698   TF7L2_HUMAN
MINT-1792780   LAP2_HUMAN
MINT-1792796   PKP4_HUMAN
MINT-2839028   LAP2B_HUMAN
MINT-2839079   EMD_HUMAN
MINT-4085223   CADH5_HUMAN
MINT-4085261   PARD3_HUMAN
MINT-4085491   CADH2_HUMAN
MINT-4508051   GSK3B_HUMAN
MINT-4508065   ITF2_HUMAN
MINT-4508192   AXN1_HUMAN
MINT-4508216   ABL1_HUMAN
MINT-4508229   APC_HUMAN
MINT-6823807   HDAC1_HUMAN
MINT-7023862   NFKB1_HUMAN
MINT-7952417   TNIK_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
R-SMAD binding, cadherin binding, androgen receptor binding, alpha-catenin binding, kinase binding, protein phosphatase binding, transcription coactivator activity, promoter binding, signal transducer activity, estrogen receptor binding, I-SMAD binding, protein C-terminus binding	Axin-APC-beta-catenin-GSK3B complex, catenin complex, transcription factor complex, perinuclear region of cytoplasm, cell cortex, protein-DNA complex, beta-catenin-TCF7L2 complex, centrosome, cell-substrate adherens junction, lateral plasma membrane	positive regulation of gene-specific transcription from RNA polymerase II promoter, patterning of blood vessels, protein localization at cell surface, positive regulation of heparan sulfate proteoglycan biosynthetic process, negative regulation of cell proliferation, cellular response to indole-3-methanol, response to drug, positive regulation of anti-apoptosis, positive regulation of apoptosis, canonical Wnt receptor signaling pathway, regulation of calcium ion import, androgen receptor signaling pathway, adherens junction assembly, regulation of fibroblast proliferation, epithelial to mesenchymal transition, regulation of smooth muscle cell proliferation, cell-cell adhesion, cellular response to growth factor stimulus, positive regulation of epithelial to mesenchymal transition, regulation of angiogenesis, endothelial tube morphogenesis, negative regulation of apoptosis, transcription, regulation of centriole-centriole cohesion, regulation of centromeric sister chromatid cohesion, response to estradiol stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	45	IHSGATTTAPSLSGKGNPEEE	CK1_group	12000790	LTP	0.80		-	-	0.88	-	-

Substrate:

BID (Ligand)

Seq-ID:

P55957 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-24750 1433B_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
death receptor binding	membrane fraction, cytosol, mitochondrial outer membrane	release of cytochrome c from mitochondria, induction of apoptosis via death domain receptors, neuron apoptosis, activation of pro-apoptotic gene products

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	59	PQWEGYDELQTDGNRSSHSRL	CK1_group	11583622	LTP	1.00		-	BID	0.56	-	-
S	64	YDELQTDGNRSSHSRLGRIEA	CK1_group	11583622	LTP	0.19	MOD_CK1_1	-	BID	0.58	-	-

Substrate:

Casein kinase I, epsilon (Casein kinase I, epsilon isoform)

Seq-ID:

P49674 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-67492   DVL2_HUMAN
MINT-1892205   OCLN_HUMAN
MINT-7264275   1433F_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein binding	cytosol, nucleus	protein amino acid phosphorylation, DNA repair, signal transduction, positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	323	REERMGQLRGSATRALPPGPP	CK1_group	10542239	LTP	0.08		-	-	0.83	-	medium
T	325	ERMGQLRGSATRALPPGPPTG	CK1_group	10542239	LTP	0.09		-	-	0.83	-	medium
T	334	ATRALPPGPPTGATANRLRSA	CK1_group	10542239	LTP	0.00		-	-	0.79	-	medium
T	337	ALPPGPPTGATANRLRSAAEP	CK1_group	10542239	LTP	0.05		-	-	0.79	-	medium
S	368	PAGNTSPRAISRVDRERKVSM	CK1_group	10542239	LTP	0.42		-	-	0.73	-	medium
S	405	GRQEVSRIPASQTSVPFDHLG	CK1_group	10542239	LTP	0.18	MOD_CK1_1	-	-	0.78	-	medium
T	407	QEVSRIPASQTSVPFDHLGK	CK1_group	10542239	LTP	0.00	MOD_CK1_1	-	-	0.77	-	medium
S	408	EVSRIPASQTSVPFDHLGK	CK1_group	10542239	LTP	0.07	MOD_CK1_1	-	-	0.77	-	medium

Substrate:

CDK5 (Cell division protein kinase 5)

Seq-ID:

Q00535 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-3974182 TAU_HUMAN
MINT-3974239 TAU_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ErbB-3 class receptor binding, tau-protein kinase activity, acetylcholine receptor activator activity, ErbB-2 class receptor binding, cyclin-dependent protein kinase activity, ATP binding	neuronal cell body, dendrite, neuromuscular junction, cytosol, lamellipodium, axon, growth cone, membrane	cell division, positive regulation of neuron apoptosis, cell proliferation, embryo development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	159	RAFGIPVRCYSAEVVTLWYRP	CK1_group	10500146	LTP	0.93		-	S_TKc	0.03	1UNG	50.00%

Substrate:

Galectin-3 (galectin-3 (galactose-specific lectin 3) (mac-2 antigen) (from PhosphoBase))

Seq-ID:

P38486 [Canis familiaris]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
IgE binding, sugar binding	nucleus	cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	MADSFSLNDALSGSGN	CK1_group	8253806	LTP	0.89		-	-	0.83	-	low
S	12	ADSFSLNDALSGSGNPNPQGW	CK1_group	8253806	LTP	0.38		-	-	0.89	-	low

Substrate:

glycogen synthase (Glycogen [starch] synthase, muscle)

Seq-ID:

P13834 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
glycogen (starch) synthase activity, protein binding		glycogen biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	MPLSRTLSVSSLPGLEDW	CK1_group	2117608	LTP	0.29	MOD_CK1_1	-	-	0.32	-	low
S	11	MPLSRTLSVSSLPGLEDWEDE	CK1_group	2498326	LTP	0.26	MOD_CK1_1	-	-	0.31	-	low
S	11	MPLSRTLSVSSLPGLEDWEDE	CK1_group	2117608	LTP	0.26	MOD_CK1_1	-	-	0.31	-	low

Substrate:

IPP2 (protein phosphatase inhibitor 2 (IPP-2) (from PhosphoBase))

Seq-ID:

P11845 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity		regulation of phosphoprotein phosphatase activity, regulation of signal transduction, glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	87	SMIGDDDDAYSDTETTEAMTP	CK1_group	2117608	LTP	1.00		-	IPP-2	0.81	-	medium
S	175	LHDDEEDEEMSETADGESMNT	CK1_group	1319929	LTP	0.54		-	-	0.96	-	medium

Substrate:

NFAT4 (Nuclear factor of activated T-cells, GO:0005737ic 3 (T cell transcription factor NFAT4) (NF-ATc3) (NF-AT4))

Seq-ID:

Q12968 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytoplasm, nucleus	transcription from RNA polymerase II promoter, inflammatory response

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	204	SELNEAAARFTLGSPLTSPGG	CK1_group	9630228	LTP	1.00		-	-	0.70	-	low
S	207	NEAAARFTLGSPLTSPGGSPG	CK1_group	9630228	LTP	1.00	MOD_CK1_1	-	-	0.70	-	low
T	210	AARFTLGSPLTSPGGSPGGCP	CK1_group	9630228	LTP	0.91	MOD_CK1_1	-	-	0.71	-	low
S	211	ARFTLGSPLTSPGGSPGGCPG	CK1_group	9630228	LTP	1.00	MOD_CK1_1	-	-	0.71	-	low
S	215	LGSPLTSPGGSPGGCPGEETW	CK1_group	9630228	LTP	1.00		-	-	0.77	-	low

Substrate:

p53 (Cellular tumor antigen p53)

Seq-ID:

P04637 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13742   CHK2_HUMAN
MINT-15878   UBP7_HUMAN
MINT-16161   BRCA1_HUMAN
MINT-16977   PARP1_HUMAN
MINT-19990   PIN1_HUMAN
MINT-24859   ASPP2_HUMAN
MINT-45889   CEBPZ_HUMAN
MINT-49767   ATM_HUMAN
MINT-50577   SAE1_HUMAN
MINT-56524   SP1_HUMAN
MINT-58470   MED1_HUMAN
MINT-58672   HNRL1_HUMAN
MINT-60094   HIPK2_HUMAN
MINT-61312   MK08_HUMAN
MINT-61317   WWOX_HUMAN
MINT-62206   PP1A_HUMAN
MINT-63290   ARI2_HUMAN
MINT-63365   KITH_HUMAN
MINT-63497   ZNF24_HUMAN
MINT-63537   IF2B_HUMAN
MINT-63547   RAB4A_HUMAN
MINT-63559   SAT1_HUMAN
MINT-64119   STX5_HUMAN
MINT-64188   MD2BP_HUMAN
MINT-64748   K0087_HUMAN
MINT-65132   HSPB1_HUMAN
MINT-65272   MPH6_HUMAN
MINT-68565   BMX_HUMAN
MINT-74886   NPM_HUMAN
MINT-74925   1433Z_HUMAN
MINT-1795431   NMT1_HUMAN
MINT-1891378   CDN1A_HUMAN
MINT-1958329   CHK1_HUMAN
MINT-2634790   RGRF1_HUMAN
MINT-2858243   DVL2_HUMAN
MINT-2866927   SCAM1_HUMAN
MINT-3390028   KC1D_RAT
MINT-3979604   P53_MOUSE
MINT-4049689   NR4A1_HUMAN
MINT-4052116   SYVN1_HUMAN
MINT-4052873   GRP78_HUMAN
MINT-4302642   HS71L_HUMAN
MINT-4303978   XPO1_HUMAN
MINT-4329805   TOPRS_HUMAN
MINT-4793180   EGR1_HUMAN
MINT-4793253   GSK3B_HUMAN
MINT-4793489   PML_HUMAN
MINT-5114724   ZN363_HUMAN
MINT-5207405   HDAC8_HUMAN
MINT-6540866   PSME3_HUMAN
MINT-6540889   MDM2_HUMAN
MINT-6628692   LT_SV40
MINT-6665320   CBP_HUMAN
MINT-6701342   MAP1B_HUMAN
MINT-7013631   PA1_HUMAN
MINT-7013916   RYBP_HUMAN
MINT-7103733   ANDR_HUMAN
MINT-7144912   TOE1_HUMAN
MINT-7222784   FRAP_HUMAN
MINT-7263630   EP300_HUMAN
MINT-7266250   PLK1_HUMAN
MINT-7294020   FAK1_HUMAN
MINT-7295816   IKKB_HUMAN
MINT-7557644   GRP75_HUMAN
MINT-7711943   1433S_HUMAN
MINT-7717378   PHB_HUMAN
MINT-7718917   SNAI1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription activator activity, protease binding, DNA strand annealing activity, chromatin binding, copper ion binding, ATP binding, transcription factor binding, chaperone binding, zinc ion binding, histone acetyltransferase binding, promoter binding, sequence-specific DNA binding transcription factor activity, protein N-terminus binding, protein heterodimerization activity, protein phosphatase 2A binding, protein kinase binding, ubiquitin protein ligase binding	nucleolus, nuclear matrix, insoluble fraction, protein complex, endoplasmic reticulum, PML body, mitochondrion	positive regulation of gene-specific transcription from RNA polymerase II promoter, senescence, mitotic cell cycle G1/S DNA damage checkpoint, cell cycle arrest, regulation of mitochondrial membrane permeability, response to gamma radiation, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, response to tumor cell, ER overload response, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, interspecies interaction between organisms, Ras protein signal transduction, nucleotide-excision repair, protein tetramerization, cellular response to glucose starvation, negative regulation of helicase activity, negative regulation of cell growth, base-excision repair, activation of caspase activity by cytochrome c, cell aging

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	18	PSVEPPLSQETFSDLWKLLPE	CK1_group	10606744	LTP	1.00	MOD_CK1_1	-	P53_TAD	0.64	-	-

Substrate:

p53 (Cellular tumor antigen p53)

Seq-ID:

P10361 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
RNA polymerase II transcription factor activity, ubiquitin protein ligase binding, DNA strand annealing activity, copper ion binding, ATP binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, transcription repressor activity, sequence-specific DNA binding, protein C-terminus binding	cytosol, transcription factor complex, nucleolus, soluble fraction, endoplasmic reticulum, mitochondrion, chromatin	positive regulation of gene-specific transcription from RNA polymerase II promoter, response to amino acid stimulus, response to oxidative stress, response to drug, response to vitamin B3, cell cycle, positive regulation of apoptosis, negative regulation of smooth muscle cell proliferation, response to cytokine stimulus, response to X-ray, response to tumor cell, regulation of intracellular pH, response to caffeine, nucleotide-excision repair, response to retinoic acid, wound healing, multicellular organismal development, response to hyperoxia, positive regulation of leukocyte migration, response to metal ion, response to UV, transcription, negative regulation of cell growth, positive regulation of cell cycle, activation of caspase activity by cytochrome c, cell aging

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	MEDSQSDMSIELPLSQ	CK1_group	7862459	LTP	0.18	MOD_CK1_1	-	P53_TAD	0.73	-	medium
S	9	MEDSQSDMSIELPLSQETF	CK1_group	7862459	LTP	0.75	MOD_CK1_1	-	P53_TAD	0.65	-	medium

Substrate:

Presenilin 2 (Integral membrane protein)

Seq-ID:

P49810 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13995   FLNA_HUMAN
MINT-14380   FLNB_HUMAN
MINT-14946   B2CL1_HUMAN
MINT-16271   FHL2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	centrosome, Golgi membrane, nuclear inner membrane, integral to plasma membrane, kinetochore, endoplasmic reticulum membrane	induction of apoptosis by extracellular signals, membrane protein ectodomain proteolysis, apoptosis, Notch receptor processing, membrane protein intracellular domain proteolysis, positive regulation of catalytic activity, Notch signaling pathway, amyloid precursor protein catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	7	MLTFMASDSEEEVCDER	CK1_group	8972483	LTP	0.11	MOD_CK2_1	-	-	0.52	-	medium
S	9	MLTFMASDSEEEVCDERTS	CK1_group	8972483	LTP	0.94	MOD_CK2_1	-	-	0.53	-	medium
S	19	SEEEVCDERTSLMSAESPTPR	CK1_group	8972483	LTP	0.25	MOD_CK1_1	-	-	0.72	-	medium

Substrate:

Synaptic vesicular amine transporter (Membrane transport protein)

Seq-ID:

Q05940 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
monoamine transmembrane transporter activity	membrane fraction, integral to plasma membrane, cytoplasmic vesicle membrane	neurotransmitter transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	511	QSYPIGEDEESESD	CK1_group	9045708	LTP	0.11		-	-	0.68	-	medium
S	513	YPIGEDEESESD	CK1_group	9045708	LTP	0.00		-	-	0.50	-	medium