List of substrates found:


Substrate: Alpha-NAC (Unclassified)
Seq-ID: Q13765 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 159 AVSNIQENTQTPTVQEESEEE GSK-3_beta 15005626
LTP
0.77
MOD_GSK3_1
- -
0.79
- medium

Substrate: Amyloid beta A4 protein (Cell surface receptor)
Seq-ID: P05067 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 743 HGVVEVDAAVTPEERHLSKMQ GSK-3_beta 8764598
LTP
1.00
- APP_amyloid
0.47
--

Substrate: Ataxin 3 (DNA repair protein)
Seq-ID: P54252 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 256 EADLRRAIQLSMQGSSRNISQ GSK-3_beta 17434145
LTP
1.00
MOD_GSK3_1
- UIM
0.63
- medium

Substrate: Axin1 (Adapter molecule)
Seq-ID: O35625 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 480 LDEHVQRVMRTPGCQSPGPGH GSK-3_beta 10581160
LTP
1.00
- Axin_b-cat_bind
0.84
- medium
S 485 QRVMRTPGCQSPGPGHRSPDS GSK-3_beta 10581160
LTP
1.00
- Axin_b-cat_bind
0.91
- medium

Substrate: c-myc (Myc proto-oncogene protein (c-myc))
Seq-ID: P01106 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 58 DIWKKFELLPTPPLSPSRRSG GSK-3_beta 14563837
LTP
1.00
MOD_GSK3_1
- Myc_N
0.38
- low

Substrate: C/EBP beta (Transcription factor)
Seq-ID: P28033 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 179 TPSGSSGSLSTSSSSSPPGTP GSK-3_beta 15985551
LTP
0.29
MOD_GSK3_1
- -
0.88
- medium
S 184 SGSLSTSSSSSPPGTPSPADA GSK-3_beta 15985552
LTP
0.18
MOD_GSK3_1
- -
0.87
- medium

Substrate: CCND3 (protein binding)
Seq-ID: P30281 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 283 SSSQGPSQTSTPTDVTAIHL  GSK-3_beta 15326477
LTP
0.98
MOD_GSK3_1
- Cyclin_C
0.74
- medium
T 283 SSSQGPSQTSTPTDVTAIHL  GSK-3_beta 15252116
LTP
0.98
MOD_GSK3_1
- Cyclin_C
0.74
- medium

Substrate: CD227 (CD antigen)
Seq-ID: P15941 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
extracellular region,
cytoplasm,
integral to plasma membrane,
nucleus,
apical plasma membrane
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 1227 RYVPPSSTDRSPYEKVSAGNG GSK-3_beta 9819408
LTP
0.24
MOD_GSK3_1
- -
0.55
- low

Substrate: Cryptochrome-2 (Transcription regulatory protein)
Seq-ID: Q9R194 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 553 ISNTGPRALSSGPASPKRKLE GSK-3_beta 15980066
LTP
0.10
MOD_GSK3_1
- -
0.74
- low
S 557 GPRALSSGPASPKRKLEAAEE GSK-3_beta 15980066
LTP
0.33
MOD_GSK3_1
- -
0.79
- low

Substrate: Cyclin D1 (Cyclin D1)
Seq-ID: P25322 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 286 EVEEEAGLACTPTDVRDVDI  GSK-3_beta 15075324
LTP
1.00
- Cyclin_C
0.44
- medium
T 286 EVEEEAGLACTPTDVRDVDI  GSK-3_beta 11124803
LTP
1.00
- Cyclin_C
0.44
- medium

Substrate: Cyclin E1 (Cell cycle control protein)
Seq-ID: P24864 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 395 RASPLPSGLLTPPQSGKKQSS GSK-3_beta 14536078
LTP
1.00
MOD_GSK3_1
- -
0.77
--

Substrate: DRP-2 (Cytoskeletal associated protein)
Seq-ID: Q16555 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 509 YDGPVCEVSVTPKTVTPASSA GSK-3_beta 15466863
LTP
0.56
- -
0.52
- medium
T 514 CEVSVTPKTVTPASSAKTSPA GSK-3_beta 15466863
LTP
0.67
MOD_GSK3_1
- -
0.65
- medium
T 514 CEVSVTPKTVTPASSAKTSPA GSK-3_beta 15652488
LTP
0.67
MOD_GSK3_1
- -
0.65
- medium
S 518 VTPKTVTPASSAKTSPAKQQA GSK-3_beta 15466863
LTP
0.72
MOD_GSK3_1
- -
0.78
- medium

Substrate: DRP-3 (Dihydropyrimidinase related protein-3)
Seq-ID: ENSP00000343690 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
Molecular FunctionCellular ComponentBiological Process
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 623 YDGPVFDLTTTPKGGTPAGSA GSK-3_beta 15466863
LTP
0.68
- -
0.65
- medium
T 628 FDLTTTPKGGTPAGSARGSPT GSK-3_beta 15466863
LTP
0.75
MOD_GSK3_1
- -
0.81
- medium
S 632 TTPKGGTPAGSARGSPTRPNP GSK-3_beta 15466863
LTP
0.74
MOD_GSK3_1
- -
0.92
- medium

Substrate: Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )
Seq-ID: P03372 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 102 NGLGGFPPLNSVSPSPLMLLH GSK-3_beta 16076840
LTP
0.85
MOD_GSK3_1
- Oest_recep
0.46
--
S 104 LGGFPPLNSVSPSPLMLLHPP GSK-3_beta 10949034
LTP
0.61
MOD_GSK3_1
- Oest_recep
0.48
--
S 104 LGGFPPLNSVSPSPLMLLHPP GSK-3_beta 16076840
LTP
0.61
MOD_GSK3_1
- Oest_recep
0.48
--
S 106 GFPPLNSVSPSPLMLLHPPPQ GSK-3_beta 16076840
LTP
0.96
MOD_GSK3_1
- Oest_recep
0.52
--
S 118 LMLLHPPPQLSPFLQPHGQQV GSK-3_beta 16076840
LTP
1.00
MOD_ProDKin_1
- Oest_recep
0.50
--

Substrate: glycogen synthase (Glycogen [starch] synthase, muscle)
Seq-ID: P13807 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
glycogen (starch) synthase activity,
protein binding
glycogen biosynthetic process
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 641 AQGYRYPRPASVPPSPSLSRH GSK-3_beta 6772446
LTP
1.00
MOD_GSK3_1
- Glycogen_syn
0.72
- medium
S 645 RYPRPASVPPSPSLSRHSSPH GSK-3_beta 6772446
LTP
1.00
MOD_GSK3_1
- Glycogen_syn
0.82
- medium
S 649 PASVPPSPSLSRHSSPHQSED GSK-3_beta 6772446
LTP
1.00
MOD_GSK3_1
- Glycogen_syn
0.90
- medium

Substrate: hnRPD (Ribonucleoprotein)
Seq-ID: Q14103 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 83 NEEDEGHSNSSPRHSEAATAQ GSK-3_beta 12819195
LTP
- MOD_GSK3_1
- -
0.92
--

Substrate: IPP2 (protein phosphatase inhibitor 2 (IPP-2) (from PhosphoBase))
Seq-ID: P41236 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 73 YGLMKIDEPSTPYHSMMGDDE GSK-3_beta 12761178
LTP
1.00
MOD_GSK3_1
- IPP-2
0.70
- high

Substrate: MCL1 (protein binding, protein channel activity)
Seq-ID: Q07820 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 159 ESGNNTSTDGSLPSTPPPAEE GSK-3_beta 16543145
LTP
1.00
MOD_GSK3_1
- -
0.96
- low

Substrate: Mdm2 (Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2. -) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2))
Seq-ID: P23804 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 254 SVEFEVESLDSEDYSLSDEGH GSK-3_beta 16055726
LTP
1.00
MOD_GSK3_1
- -
0.58
- medium

Substrate: Microphthalmia-associated transcription factor (Transcription factor)
Seq-ID: O75030-2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription activator activity nucleus melanocyte differentiation,
transcription
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 399 LEMQARAHGLSLIPSTGLCSP GSK-3_beta 10587587
LTP
0.20
MOD_GSK3_1
- -
0.40
- medium

Substrate: MKI67IP (protein binding, RNA binding)
Seq-ID: Q9BYG3 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 230 TLDTPEKTVDSQGPTPVCTPT GSK-3_beta 16244663
LTP
1.00
MOD_GSK3_1
- -
0.68
- medium
T 234 PEKTVDSQGPTPVCTPTFLER GSK-3_beta 16244663
LTP
1.00
MOD_GSK3_1
MKI67 FHA -
0.65
- medium

Substrate: Notch2 (Cell surface receptor)
Seq-ID: O35516 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 2066 IVRLLDEYNVTPSPPGTVLTS GSK-3_beta 12794074
LTP
0.00
MOD_GSK3_1
- -
0.47
- medium
S 2068 RLLDEYNVTPSPPGTVLTSAL GSK-3_beta 12794074
LTP
1.00
MOD_GSK3_1
- -
0.49
- medium
T 2072 EYNVTPSPPGTVLTSALSPVL GSK-3_beta 12794074
LTP
0.08
MOD_GSK3_1
- -
0.52
- medium
S 2091 VLCGPNRSFLSLKHTPMGKKA GSK-3_beta 12794074
LTP
0.25
MOD_GSK3_1
- -
0.55
- medium

Substrate: Nuclear factor NF-kappa-B p105 subunit (Nuclear factor NF-kappa-B p105 subunit)
Seq-ID: P19838 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 903 SPVKTTSQAHSLPLSPASTRQ GSK-3_beta 12871932
LTP
- MOD_GSK3_1
- -
0.66
--
S 907 TTSQAHSLPLSPASTRQQIDE GSK-3_beta 12871932
LTP
- MOD_GSK3_1
- -
0.62
--

Substrate: p21 (Cyclin-dependent kinase inhibitor 1 (p21))
Seq-ID: P38936 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 57 ERWNFDFVTETPLEGDFAWER GSK-3_beta 11779850
LTP
1.00
MOD_ProDKin_1
- CDI
0.36
- medium
S 114 GTAEEDHVDLSLSCTLVPRSG GSK-3_beta 17283049
LTP
0.04
MOD_GSK3_1
- -
0.49
- medium

Substrate: p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID: Q04206 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 468 TDPAVFTDLASVDNSEFQQLL GSK-3_beta 15465828
LTP
0.91
MOD_GSK3_1
- -
0.53
--

Substrate: Presenilin 1 (Presenilin 1 (PS-1) (S182 protein))
Seq-ID: P49768 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 353 QRDSHLGPHRSTPESRAAVQE GSK-3_beta 11104755
LTP
0.15
MOD_GSK3_1
- PSN
0.59
- medium
S 357 HLGPHRSTPESRAAVQELSSS GSK-3_beta 11104755
LTP
0.93
MOD_GSK3_1
- PSN
0.48
- medium

Substrate: PTEN (Lipid phosphatase)
Seq-ID: P60484 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 362 EEPSNPEASSSTSVTPDVSDN GSK-3_beta 16107342
LTP
0.79
MOD_GSK3_1
- -
0.87
--
T 366 NPEASSSTSVTPDVSDNEPDH GSK-3_beta 16107342
LTP
0.79
MOD_GSK3_1
- -
0.83
--

Substrate: Rap1GAP (GTPase activating protein)
Seq-ID: P47736 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 525 SPPAGQKTPDSGHVSQEPKSE GSK-3_beta 14660640
LTP
0.89
MOD_GSK3_1
- -
0.95
- low

Substrate: SNAI1 (Transcription regulatory protein)
Seq-ID: O95863 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 104 EDSGKGSQPPSPPSPAPSSFS GSK-3_beta 15647282
LTP
0.41
MOD_GSK3_1
- -
0.89
- low
S 107 GKGSQPPSPPSPAPSSFSSTS GSK-3_beta 15647282
LTP
0.58
MOD_GSK3_1
- -
0.82
- low

Substrate: tau (Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau))
Seq-ID: P10636 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 548 REPKKVAVVRTPPKSPSSAKS GSK-3_beta 9565682
LTP
1.00
MOD_GSK3_1
- -
0.89
- medium
S 552 KVAVVRTPPKSPSSAKSRLQT GSK-3_beta 9565682
LTP
1.00
MOD_GSK3_1
- -
0.87
- medium
S 575 VPMPDLKNVKSKIGSTENLKH GSK-3_beta 12714590
LTP
1.00
MOD_GSK3_1
- Tubulin-binding
0.81
- medium
S 579 DLKNVKSKIGSTENLKHQPGG GSK-3_beta 12714590
LTP
1.00
MOD_GSK3_1
- Tubulin-binding
0.83
- medium
S 713 TDHGAEIVYKSPVVSGDTSPR GSK-3_beta 9565682
LTP
1.00
MOD_GSK3_1
- -
0.57
- medium
S 721 YKSPVVSGDTSPRHLSNVSST GSK-3_beta 9565682
LTP
1.00
MOD_GSK3_1
- -
0.61
- medium

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