List of substrates found:


Substrate: Band 3 anion transport protein (Anion exchange protein 1)
Seq-ID: P02730 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 8    MEELQDDYEDMMEENLEQ Lyn 10942405
LTP
0.00
Lyn SH2 -
0.80
--
Y 21 MMEENLEQEEYEDPDIPESQM Lyn 10942405
LTP
0.79
Lyn SH2 -
0.89
--
Y 359 SSPAKPDSSFYKGLDLNGGPD Lyn 10942405
LTP
0.11
PTPN11 SH2 -
0.45
--
Y 904 TFDEEEGRDEYDEVAMPV    Lyn 10942405
LTP
1.00
- -
0.37
--

Substrate: BTK (Bruton's tyrosine kinase)
Seq-ID: Q06187 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 551 GLSRYVLDDEYTSSVGSKFPV Lyn 8630736
LTP
1.00
- TyrKc
0.10
1K2P 8.73%

Substrate: Casein kinase II, alpha chain (casein kinase II, alpha chain (CKII) (EC 2.7.1.37) (from PhosphoBase))
Seq-ID: P68400 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 255 IAKVLGTEDLYDYIDKYNIEL Lyn 12628006
LTP
0.49
- S_TKc
0.09
3H30 17.90%

Substrate: CD150 (T cell antigen receptor)
Seq-ID: Q13291 [Homo sapiens]
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 327 SVQETNSITVYASVTLPES   Lyn 15315965
LTP
1.00
FGR SH2;
INPP5D SH2;
PTPN11 SH2;
SH2D1A SH2;
SH2D1B SH2
-
0.38
- low

Substrate: CD19 (Antigen of human B-lymphocytes)
Seq-ID: P15391 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 500 REATSLGSQSYEDMRGILYAA Lyn 10933394
LTP
1.00
PIK3R1 SH2 -
0.73
- medium
Y 531 GPNHEEDADSYENMDNPDGPD Lyn 10933394
LTP
1.00
PIK3R1 SH2 -
0.97
- medium

Substrate: CD32 (CD antigen. Binds to the Fc region of immunoglobulins gamma.)
Seq-ID: P12318 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
IgG binding
plasma membrane,
integral to membrane
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 281 KRQLEETNNDYETADGGYMTL Lyn 8756631
LTP
1.00
- -
0.57
- low
Y 288 NNDYETADGGYMTLNPRAPTD Lyn 8756631
LTP
0.46
LIG_TYR_ITAM
- -
0.66
- low
Y 304 RAPTDDDKNIYLTLPPNDHVN Lyn 8756631
LTP
0.08
LIG_TYR_ITAM
- -
0.66
- low

Substrate: CD79A (B cell antigen receptor)
Seq-ID: P11912 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 188 AGDEYEDENLYEGLNLDDCSM Lyn 9531288
LTP
1.00
LIG_TYR_ITAM
BLK SH2;
SHC1 SH2;
SYK SH2
ITAM
0.35
- low

Substrate: CD79B (B cell antigen receptor)
Seq-ID: P40259 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 196 SKAGMEEDHTYEGLDIDQTAT Lyn 9531288
LTP
- LIG_TYR_ITAM
BLK SH2 ITAM
0.48
- medium
Y 207 EGLDIDQTATYEDIVTLRTGE Lyn 9531288
LTP
- LIG_TYR_ITAM
BLK SH2 ITAM
0.23
- medium

Substrate: Epo-R (Receptor for erythropoietin, a major activator of erythropoiesis)
Seq-ID: P19235 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
erythropoietin receptor activity extracellular region,
integral to plasma membrane
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 368 PVGSEHAQDTYLVLDKWLLPR Lyn 10579919
LTP
1.00
CISH SH2;
INPP5D SH2;
PLCG2 SH2;
STAT5 SH2;
SYK SH2
-
0.32
- low

Substrate: FCGR2B (protein binding)
Seq-ID: P31994 [Homo sapiens]
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 292 DKVGAENTITYSLLMHPDALE Lyn 8756631
LTP
1.00
INPP5D SH2;
Lyn SH2;
PIK3R1 SH2;
PTPN11 SH2;
PTPN6 SH2;
SHC1 SH2
-
0.42
- low

Substrate: FCGR2C (transmembrane receptor activity)
Seq-ID: P31995 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 310 RAPTDDDKNIYLTLPPNDHVN Lyn 8756631
LTP
0.83
LIG_TYR_ITAM
- -
0.67
- medium

Substrate: LckBP1 (Hematopoietic cell-specific LYN substrate 1)
Seq-ID: P14317 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 222 FNEMEAPTTAYKKTTPIEAAS Lyn 10066823
LTP
1.00
- HS1_rep
0.68
- medium
Y 378 PEPEPEPENDYEDVEEMDRHE Lyn 9104825
LTP
0.18
Lyn SH2 -
0.98
- medium
Y 397 HEQEDEPEGDYEEVLEPEDSS Lyn 9104825
LTP
0.80
Lyn SH2 -
0.95
- medium

Substrate: Leupaxin (may assemble and regulate leukocyte signalling complexes 2)
Seq-ID: Q99N69 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
zinc ion binding cytoplasm
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 72 YATNIQEPNVYSEVQEPKESV Lyn 17640867
LTP
0.14
- -
0.60
- medium

Substrate: Microtubule associated protein 2 (Cytoskeletal protein)
Seq-ID: P11137 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 67 AFGEHGSQGTYSNTKENGING Lyn 15536091
LTP
1.00
GRB2 SH2 -
0.85
- medium

Substrate: NIPP1 (RNA binding protein)
Seq-ID: Q12972 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 264 MQNFAFSGGLYGGLPPTHSEA Lyn 11104670
LTP
1.00
- -
0.56
- medium
Y 335 EAVNEPKKKKYAKEAWPGKKP Lyn 11104670
LTP
1.00
- -
0.70
- medium

Substrate: NMT1 (Unclassified)
Seq-ID: P30419 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 117 KTMEEASKRSYQFWDTQPVPK Lyn 11594778
LTP
0.89
- -
0.54
--
Y 180 KELYTLLNENYVEDDDNMFRF Lyn 11594778
LTP
1.00
- NMT
0.13
1RXT 25.33%

Substrate: PAG1
Seq-ID: Q3U1F9 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 386 RRPSEEPEPDYEAIQTLNRED Lyn 16920712
LTP
1.00
- -
0.88
- low
Y 414 NGHHVPKESDYESIGDLQQCR Lyn 16920712
LTP
1.00
- -
0.71
- low

Substrate: PKC delta (Protein kinase C, delta)
Seq-ID: P28867 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 52 KTLVQKKPTMYPEWKTTFDAH Lyn 7575560
LTP
0.95
- C2
0.32
- low
Y 155 RGAIKQAKIHYIKNHEFIATF Lyn 7575560
LTP
0.37
- -
0.11
- low
Y 565 FESIRVDTPHYPRWITKESKD Lyn 7575560
LTP
1.00
- S_TKc
0.26
- low

Substrate: PLC gamma 2 (Involved in transmembrane signaling)
Seq-ID: P16885 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 743 YPVTPELLERYNMERDINSLY Lyn 12181444
LTP
0.05
- -
0.27
- medium

Substrate: Protein disulfide-isomerase A3 precursor (Protein disulfide isomerase family)
Seq-ID: P11598 [Rattus norvegicus]
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 445 DATANDVPSPYEVKGFPTIYF Lyn 8631326
LTP
0.32
- Thioredoxin
0.36
- low
Y 454 PYEVKGFPTIYFSPANKKLTP Lyn 8631326
LTP
0.98
- Thioredoxin
0.31
- low
Y 467 PANKKLTPKKYEGGRELNDFI Lyn 8631326
LTP
1.00
- Thioredoxin
0.41
- low

Substrate: RGS16 (Regulator of G-protein signaling 16)
Seq-ID: O15492 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 177 SYPRFLKSPAYRDLAAQASAA Lyn 12588871
LTP
1.00
Src SH2 RGS
0.29
2BT2 0.87%

Substrate: STAT 5 (Transcription factor)
Seq-ID: P42229 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 694 TPVLAKAVDGYVKPQIKQVVP Lyn 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium

Substrate: SYK (Spleen tyrosine kinase )
Seq-ID: P48025 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 130 EDLKENLIREYVKQTWNLQGQ Lyn 9820500
LTP
1.00
- -
0.28
--
Y 317 RPESTVSFNPYEPTGGPWGPD Lyn 9820500
LTP
1.00
CBL SH2 -
0.69
--
Y 342 REALPMDTEVYESPYADPEEI Lyn 9820500
LTP
1.00
PLCG_group SH2;
VAV1 SH2
-
0.58
--
Y 346 PMDTEVYESPYADPEEIRPKE Lyn 9820500
LTP
1.00
PLCG_group SH2 -
0.54
--

Substrate: Tyrosine-protein kinase Lyn (Tyr protein kinase family)
Seq-ID: P07948 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 397 GLARVIEDNEYTAREGAKFPI Lyn 8530369
LTP
0.86
- TyrKc
0.16
- medium

Substrate: Tyrosine-protein kinase Lyn (Tyr protein kinase family)
Seq-ID: P25911 [Mus musculus]
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 397 GLARVIEDNEYTAREGAKFPI Lyn 10415030
LTP
0.88
- TyrKc
0.16
--

Substrate: Vanilloid receptor like channel 2 (Membrane transport protein)
Seq-ID: Q9EPK8 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 253 HIAIERRCKHYVELLVAQGAD Lyn 12538589
LTP
0.17
- ANK
0.13
- low

Substrate: Vanilloid receptor like channel 2 (Membrane transport protein)
Seq-ID: Q9HBA0 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 253 HIAIERRCKHYVELLVAQGAD Lyn 12538589
LTP
0.17
- ANK
0.12
- low

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