Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

Substrate:

ARHGDIA (protein binding, Rho GDP-dissociation inhibitor activity)

Seq-ID:

P52565 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-18849   RADI_HUMAN
MINT-63856   PLAK_HUMAN
MINT-63857   FEN1_HUMAN
MINT-63858   CDN1B_HUMAN
MINT-63860   NED4L_HUMAN
MINT-4298452   RAC1_HUMAN
MINT-4298468   SET_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
identical protein binding, GTPase activator activity, Rho GDP-dissociation inhibitor activity	cytosol, cytoskeleton	negative regulation of axonogenesis, anti-apoptosis, cellular component movement, Rho protein signal transduction, positive regulation of axonogenesis, negative regulation of cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	101	TGDLESFKKQSFVLKEGVEYR	PAK1	15225553	LTP	0.57		-	Rho_GDI	0.22	1KMT	40.98%
S	174	EAPKGMLARGSYSIKSRFTDD	PAK1	15225553	LTP	0.58		-	Rho_GDI	0.35	1KMT	58.20%

Substrate:

B-Raf (B-Raf proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P15056 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50344   1433B_HUMAN
MINT-50372   1433T_HUMAN
MINT-2833162   KPCA_HUMAN
MINT-2833238   KPCE_HUMAN
MINT-2833314   KS6A2_HUMAN
MINT-3295552   1433Z_HUMAN
MINT-3374124   M3K1_HUMAN
MINT-3975375   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, ATP binding	cytoplasm, nucleus	protein amino acid phosphorylation, organ morphogenesis, anti-apoptosis, small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	446	NRMKTLGRRDSSDDWEIPDGQ	PAK1	15710605	LTP	1.00		-	-	0.65	-	-

Substrate:

BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))

Seq-ID:

Q92934 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14699   B2CL1_HUMAN
MINT-66103   1433S_HUMAN
MINT-7034091   B2L11_HUMAN
MINT-7717137   NAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding	cytosol, mitochondrial outer membrane	induction of apoptosis by extracellular signals, activation of pro-apoptotic gene products

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	99	EPSPFRGRSRSAPPNLWAAQR	PAK1	10611223	LTP	1.00	MOD_PKB_1	-	Bcl-2_BAD	0.76	-	medium

Substrate:

CPI-17 (Inhibitor of PPP1CA)

Seq-ID:

Q91VC7 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity	cytoplasm	regulation of phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	38	SGLQKRHARVTVKYDRRELQR	PAK1	12359219	LTP	1.00		-	PP1_inhibitor	0.51	-	low

Substrate:

Dynein light chain 1, cytoplasmic (Motor activity)

Seq-ID:

P63168 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3088965 DC1I1_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein C-terminus binding, protein domain specific binding, microtubule motor activity	membrane fraction, mitochondrion, cytosol, cytoplasmic dynein complex, nucleus, microtubule	transcription, apoptosis, regulation of transcription, transport, microtubule-based movement

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	88	LGQVAILLFKSG	PAK1	15504720	LTP	0.00		-	Dynein_light	0.02	1CMI	32.79%

Substrate:

Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )

Seq-ID:

P03372 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13786   BRCA1_HUMAN
MINT-50646   STA5A_HUMAN
MINT-50709   M3K1_HUMAN
MINT-5222241   NCOA1_HUMAN
MINT-6169667   EGFR_HUMAN
MINT-6614126   SMCA4_HUMAN
MINT-6614301   CHD3_HUMAN
MINT-6614361   MTA1_HUMAN
MINT-6614421   MTA2_HUMAN
MINT-6761899   PTN1_HUMAN
MINT-6761906   PTN6_HUMAN
MINT-7013584   PA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
beta-catenin binding, nitric-oxide synthase regulator activity, estrogen response element binding, steroid binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, estrogen receptor activity	chromatin remodeling complex	response to estradiol stimulus, transcription, DNA-dependent, regulation of transcription, DNA-dependent, positive regulation of retinoic acid receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	305	PLMIKRSKKNSLALSLTADQM	PAK1	12374744	LTP	0.93		-	-	0.31	2QA8	64.75%

Substrate:

Filamin A (Anchor protein)

Seq-ID:

P21333 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13995   PSN2_HUMAN
MINT-17726   PSN1_HUMAN
MINT-48088   IKKB_HUMAN
MINT-48207   NEMO_HUMAN
MINT-48331   M3K1_HUMAN
MINT-48481   M3K3_HUMAN
MINT-49211   TAB2_HUMAN
MINT-49436   TNR1B_HUMAN
MINT-51375   ITB1_HUMAN
MINT-51381   ITB4_HUMAN
MINT-61733   SMAD3_HUMAN
MINT-72661   HS90B_HUMAN
MINT-2984809   ZO1_HUMAN
MINT-3318808   1433Z_HUMAN
MINT-4653380   CCNB2_HUMAN
MINT-5226955   ITB7_HUMAN
MINT-7244866   ABL1_HUMAN
MINT-7246834   FYN_HUMAN
MINT-7251370   P85A_HUMAN
MINT-7252714   PLCG1_HUMAN
MINT-7253290   GRB2_HUMAN
MINT-7254876   CRK_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, GTP-Ral binding, glycoprotein binding, Rac GTPase binding, transcription factor binding, signal transducer activity, actin filament binding, Fc-gamma receptor I complex binding	plasma membrane, extracellular region, cytosol, nucleus, actin cytoskeleton, cell cortex	protein stabilization, negative regulation of transcription factor activity, cytoplasmic sequestering of protein, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein localization at cell surface, inhibition of adenylate cyclase activity by dopamine receptor signaling pathway, negative regulation of protein catabolic process, actin cytoskeleton reorganization, receptor clustering, positive regulation of transcription factor import into nucleus, actin crosslink formation, establishment of protein localization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2152	ESITRRRRAPSVANVGSHCDL	PAK1	12198493	LTP	0.88		-	IG_FLMN	0.48	2J3S	66.39%

Substrate:

Forkhead box protein L2 (Transcription regulatory protein)

Seq-ID:

P58012 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, ubiquitin conjugating enzyme binding, sequence-specific DNA binding transcription factor activity, caspase regulator activity	nucleus	extraocular skeletal muscle development, transcription, menstruation, negative regulation of transcription, positive regulation of caspase activity, DNA fragmentation involved in apoptotic nuclear change, ovarian follicle development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	263	ASYGPYTRVQSMALPPGVVNS	PAK1	12560069	LTP	0.26		-	-	0.40	-	medium

Substrate:

Gz-alpha (G protein)

Seq-ID:

P19086 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, receptor signaling protein activity	plasma membrane, nuclear envelope, endoplasmic reticulum

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	SSEEKEAARRSRRIDRHLRSE	PAK1	10531372	LTP	1.00		-	G_alpha	0.65	-	medium

Substrate:

Gz-alpha (G protein)

Seq-ID:

ENSP00000248996 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTP binding, signal transducer activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	SSEEKEAARRSRRIDRHLRSE	PAK1	10531372	LTP	-		-	G_alpha	0.65	-	medium

Substrate:

LIM domain kinase 1 (Serine/threonine kinase)

Seq-ID:

P53667 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-2833254   MK14_HUMAN
MINT-2833388   MAPK2_HUMAN
MINT-6173989   COF1_HUMAN
MINT-7228333   KAPCA_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, heat shock protein binding, zinc ion binding	cytoplasm, growth cone	protein amino acid phosphorylation, actin cytoskeleton organization, positive regulation of actin filament bundle assembly, Rho protein signal transduction, negative regulation of ubiquitin-protein ligase activity, positive regulation of axon extension

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	508	LKKPDRKKRYTVVGNPYWMAP	PAK1	10559936	LTP	1.00		-	STYKc	0.29	-	medium

Substrate:

MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1))

Seq-ID:

Q02750 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16002   KSR1_MOUSE
MINT-3391583   M3K1_HUMAN
MINT-4300484   MK01_HUMAN
MINT-7014370   RAF1_HUMAN
MINT-7014390   MK03_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, MAP kinase kinase activity, ATP binding, protein tyrosine kinase activity	cytosol	senescence, negative regulation of cell proliferation, cell cycle arrest, chemotaxis, Ras protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	298	PRPRTPGRPLSSYGMDSRPPM	PAK1	12876277	LTP	0.74	-	S_TKc	0.69	-	-
S	298	PRPRTPGRPLSSYGMDSRPPM	PAK1	9351825	LTP	0.74	-	S_TKc	0.69	-	-
S	298	PRPRTPGRPLSSYGMDSRPPM	PAK1	16129686	LTP	0.74	-	S_TKc	0.69	-	-
S	298	PRPRTPGRPLSSYGMDSRPPM	PAK1	14993270	LTP	0.74	-	S_TKc	0.69	-	-

Substrate:

Mitogen-activated protein kinase kinase kinase 1 (Ser/Thr protein kinase family. MAP kinase family)

Seq-ID:

Q62925 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-5209624 GRAP1_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
magnesium ion binding, JUN kinase kinase kinase activity, sphingolipid binding, identical protein binding, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase binding, JUN kinase binding, ATP binding, zinc ion binding, MAP/ERK kinase kinase activity, ubiquitin-protein ligase activity	membrane fraction, cytoplasm, membrane	response to osmotic stress, positive regulation of gene-specific transcription from RNA polymerase II promoter, positive regulation of viral transcription, negative regulation of actin filament bundle assembly, positive regulation of apoptosis, protein oligomerization, peptidyl-serine phosphorylation, protein amino acid autophosphorylation, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, activation of JNKK activity, protein polyubiquitination

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	67	WRRQQLRKVRSVELDQLPEQP	PAK1	12228228	LTP	0.95		-	-	0.78	-	low

Substrate:

PGM1 (phosphoglucomutase activity)

Seq-ID:

P36871 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
magnesium ion binding, phosphoglucomutase activity	cytosol	glucose metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	467	KQFSANDKVYTVEKADNFEYS	PAK1	15378030	LTP	0.27		-	PGM_PMM_IV	0.26	-	medium

Substrate:

Phosphoglycerate mutase 1 (Phosphoglycerate mutase)

Seq-ID:

P18669 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3318976 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding, bisphosphoglycerate mutase activity, 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity, phosphoglycerate mutase activity	cytosol	regulation of pentose-phosphate shunt, respiratory burst, regulation of glycolysis, glycolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	23	ESAWNLENRFSGWYDADLSPA	PAK1	12189148	LTP	0.21		-	PGAM	0.22	1YFK	9.84%
S	118	GEAQVKIWRRSYDVPPPPMEP	PAK1	12189148	LTP	1.00		-	PGAM	0.50	1YFK	20.49%

Substrate:

Protein phosphatase 1, regulatory subunit 12A (Myosin phosphatase target subunit 1)

Seq-ID:

Q10728 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase activity, protein binding	cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	697	SRQARQSRRSTQGVTLTDLQE	PAK1	12359219	LTP	1.00		-	-	0.78	-	medium

Substrate:

Raf1 (RAF proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P04049 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19324   KPYM_HUMAN
MINT-24923   RAP1A_HUMAN
MINT-45800   1433Z_HUMAN
MINT-51053   K1C19_HUMAN
MINT-51055   K1C18_HUMAN
MINT-51056   K2C8_HUMAN
MINT-56513   CNKR1_HUMAN
MINT-3389399   PAK1_HUMAN
MINT-3389607   PEBP1_HUMAN
MINT-3975386   1433S_HUMAN
MINT-6946517   RASH_HUMAN
MINT-7014370   MP2K1_HUMAN
MINT-7014449   AKT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, metal ion binding, receptor signaling protein activity, ATP binding, protein binding	plasma membrane, cytosol, mitochondrial outer membrane	protein amino acid phosphorylation, negative regulation of cell proliferation, apoptosis, Ras protein signal transduction, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	338	NKIRPRGQRDSSYYWEIEASE	PAK1	11733498	LTP	0.96	-	-	0.43	-	medium
S	338	NKIRPRGQRDSSYYWEIEASE	PAK1	10801448	LTP	0.96	-	-	0.43	-	medium
S	339	KIRPRGQRDSSYYWEIEASEV	PAK1	15849194	LTP	0.93	-	-	0.41	-	medium

Substrate:

Rho/Rac guanine nucleotide exchange factor 2 (Stimulates guanine nucleotide exchange of Rac and Rho)

Seq-ID:

ENSP00000357298 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rac guanyl-nucleotide exchange factor activity, Rac GTPase binding, microtubule binding, zinc ion binding	spindle, cytosol, ruffle membrane, Golgi apparatus, microtubule, tight junction	induction of apoptosis by extracellular signals, cell division, cell morphogenesis, apoptosis, actin filament organization, intracellular protein transport, negative regulation of microtubule depolymerization, mitosis, regulation of cell proliferation, positive regulation of NF-kappaB transcription factor activity, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	887	ARRPVDPRRRSLPAGDALYLS	PAK1	14970201	LTP	0.09		-	-	0.64	-	medium

Substrate:

Rho/Rac guanine nucleotide exchange factor 2 (Stimulates guanine nucleotide exchange of Rac and Rho)

Seq-ID:

Q92974 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3295597 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rac guanyl-nucleotide exchange factor activity, Rac GTPase binding, microtubule binding, zinc ion binding	spindle, cytosol, ruffle membrane, Golgi apparatus, microtubule, tight junction	induction of apoptosis by extracellular signals, cell division, cell morphogenesis, apoptosis, actin filament organization, intracellular protein transport, negative regulation of microtubule depolymerization, mitosis, regulation of cell proliferation, positive regulation of NF-kappaB transcription factor activity, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	885	ARRPVDPRRRSSPQAMPCT	PAK1	14970201	LTP	0.00		-	-	0.83	-	low

Substrate:

SNAI1 (Transcription regulatory protein)

Seq-ID:

O95863 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7384899   EGR1_HUMAN
MINT-7718917   P53_HUMAN
MINT-7718939   MDM2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
zinc ion binding, protein binding	cytoplasm, nucleus	mesoderm formation, epithelial to mesenchymal transition, positive regulation of epithelial to mesenchymal transition

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	246	YQCQACARTFSRMSLLHKHQE	PAK1	15833848	LTP	1.00		-	ZnF_C2H2	0.11	-	low

Substrate:

STAT 5 (Transcription factor)

Seq-ID:

P42230 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-2576447   LEPR_MOUSE
MINT-6763108   PTN1_MOUSE
MINT-7722213   AGAP2_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding transcription factor activity, signal transducer activity, protein binding, calcium ion binding	cytoplasm, nucleus	valine metabolic process, positive regulation of mast cell proliferation, oxaloacetate metabolic process, creatinine metabolic process, isoleucine metabolic process, cytokine-mediated signaling pathway, positive regulation of mitotic cell cycle, positive regulation of B cell differentiation, lipid storage, taurine metabolic process, allantoin metabolic process, fatty acid metabolic process, Peyer`s patch development, positive regulation of interleukin-2 biosynthetic process, development of secondary male sexual characteristics, citrate metabolic process, lactation, female pregnancy, JAK-STAT cascade involved in growth hormone signaling pathway, T cell homeostasis, peptidyl-tyrosine phosphorylation, 2-oxoglutarate metabolic process, development of secondary female sexual characteristics, negative regulation of erythrocyte differentiation, luteinization, positive regulation of transcription from RNA polymerase II promoter, regulation of cell adhesion, succinate metabolic process, T cell differentiation in the thymus, creatine metabolic process, natural killer cell differentiation, positive regulation of mast cell differentiation, positive regulation of activated T cell proliferation, transcription, prostate gland epithelium morphogenesis, positive regulation of natural killer cell differentiation, regulation of steroid metabolic process, epithelial cell differentiation involved in prostate gland development, positive regulation of survival gene product expression, positive regulation of gamma-delta T cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, regulation of epithelial cell differentiation, positive regulation of inflammatory response, negative regulation of mast cell apoptosis, positive regulation of multicellular organism growth

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	779	RPMDSLDARLSPPAGLFTSAR	PAK1	12732616	LTP	0.76		-	-	0.50	-	-

Substrate:

Stathmin (stathmin (phosphoprotein p19) (oncoprotein 18) (Op18) (from PhosphoBase))

Seq-ID:

P16949 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-2860477 UBQL4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
signal transducer activity, tubulin binding	cytoplasm, microtubule	intracellular signaling pathway, nervous system development, mitotic spindle organization, cell differentiation, microtubule depolymerization, response to virus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	IQVKELEKRASGQAFELILSP	PAK1	7925472	LTP	1.00		-	Stathmin	0.46	-	medium