List of substrates found:


Substrate: Alpha-synuclein (Chaperone)
Seq-ID: P37840 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 125 DMPVDPDNEAYEMPSEEGYQD SYK 11744621
LTP
0.26
- Synuclein
0.82
--
Y 133 EAYEMPSEEGYQDYEPEA    SYK 11744621
LTP
0.12
- -
0.80
--
Y 136 EMPSEEGYQDYEPEA       SYK 11744621
LTP
0.20
- -
0.81
--

Substrate: Band 3 anion transport protein (Anion exchange protein 1)
Seq-ID: P02730 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 8    MEELQDDYEDMMEENLEQ SYK 10942405
LTP
0.00
Lyn SH2 -
0.80
--
Y 21 MMEENLEQEEYEDPDIPESQM SYK 10942405
LTP
0.79
Lyn SH2 -
0.89
--
Y 359 SSPAKPDSSFYKGLDLNGGPD SYK 10942405
LTP
0.11
PTPN11 SH2 -
0.45
--
Y 904 TFDEEEGRDEYDEVAMPV    SYK 10942405
LTP
1.00
- -
0.37
--

Substrate: BLNK (Adapter molecule)
Seq-ID: Q8WV28 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 72 EQWSDDFDSDYENPDEHSDSE SYK 12456653
LTP
1.00
- -
0.81
- low
Y 84 NPDEHSDSEMYVMPAEENADD SYK 12456653
LTP
1.00
- -
0.86
- low
Y 96 MPAEENADDSYEPPPVEQETR SYK 12456653
LTP
1.00
- -
0.91
- low
Y 178 PKGLLEDEADYVVPVEDNDEN SYK 9697839
LTP
1.00
- -
0.80
- low

Substrate: CBL E3 ubiquitin protein ligase (Adaptor molecule)
Seq-ID: P22681 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 700 EQCEGEEDTEYMTPSSRPLRP SYK 9525940
LTP
0.63
CRKL SH2;
CRK SH2;
PIK3R2 SH2;
PLCG1 SH2;
VAV_group SH2
-
0.85
--
Y 731 DCDQQIDSCTYEAMYNIQSQA SYK 9525940
LTP
0.29
CRKL SH2;
CRK SH2;
Lyn SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2
-
0.47
--
Y 774 PEESENEDDGYDVPKPPVPAV SYK 9525940
LTP
0.28
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.89
--

Substrate: CD32 (CD antigen. Binds to the Fc region of immunoglobulins gamma.)
Seq-ID: P12318 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
IgG binding
plasma membrane,
integral to membrane
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 281 KRQLEETNNDYETADGGYMTL SYK 8756631
LTP
1.00
- -
0.57
- low
Y 288 NNDYETADGGYMTLNPRAPTD SYK 8756631
LTP
0.46
LIG_TYR_ITAM
- -
0.66
- low
Y 304 RAPTDDDKNIYLTLPPNDHVN SYK 8756631
LTP
0.08
LIG_TYR_ITAM
- -
0.66
- low

Substrate: Dual specificity phosphatase 3 (Dual specificity phosphatase)
Seq-ID: P51452 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 138 YSRSPTLVIAYLMMRQKMDVK SYK 12447358
LTP
1.00
- DSPc
0.17
1VHR 3.93%

Substrate: FCGR2C (transmembrane receptor activity)
Seq-ID: P31995 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 287 KRQPEETNNDYETADGGYMTL SYK 8756631
LTP
0.47
- -
0.71
- medium

Substrate: Integrin beta 3 (Platelet membrane glycoprotein IIIa)
Seq-ID: P05106 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 785 EATSTFTNITYRGT        SYK 8631894
LTP
0.98
PTPN11 SH2;
SHC1 PTB;
SYK SH2
Integrin_b_cyt
0.26
--

Substrate: LckBP1 (Hematopoietic cell-specific LYN substrate 1)
Seq-ID: P14317 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 378 PEPEPEPENDYEDVEEMDRHE SYK 9104825
LTP
0.18
Lyn SH2 -
0.98
- medium
Y 397 HEQEDEPEGDYEEVLEPEDSS SYK 9104825
LTP
0.80
Lyn SH2 -
0.95
- medium

Substrate: MAP4K1 (Hematopoietic progenitor kinase)
Seq-ID: Q92918 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 381 KQLSESSDDDYDDVDIPTPAE SYK 11514608
LTP
0.04
BLNK SH2 -
0.91
- medium

Substrate: PKC alpha (Serine/threonine kinase)
Seq-ID: P17252 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 658 IDQSDFEGFSYVNPQFVHPIL SYK 12881490
LTP
0.55
- S_TK_X
0.23
--

Substrate: PKC alpha (Serine/threonine kinase)
Seq-ID: P20444 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 658 IDQSDFEGFSYVNPQFVHPIL SYK 12881490
LTP
0.55
- S_TK_X
0.24
- medium

Substrate: PLC gamma 1 (Major substrate for eparin binding growth factor)
Seq-ID: P19174 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 771 LEKIGTAEPDYGALYEGRNPG SYK 8657103
LTP
0.12
- -
0.36
- medium
Y 783 ALYEGRNPGFYVEANPMPTFK SYK 8657103
LTP
1.00
- -
0.28
- medium

Substrate: PYK2 (Focal adhesion kinase 2)
Seq-ID: Q14289 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 402 SESCSIESDIYAEIPDETLRR SYK 8816475
LTP
1.00
Fyn SH2;
MATK SH2;
Src SH2
-
0.37
--

Substrate: SH3 domain-binding protein 2 (Adaptor molecule)
Seq-ID: ENSMUSP00000098874 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 218 LSSYPMDNEDYEHEDEDDSYL SYK 12709437
LTP
1.00
- -
0.72
- medium
Y 227 DYEHEDEDDSYLEPDSPGPMK SYK 12709437
LTP
1.00
- -
0.85
- medium
Y 490 DTGEEDSDEDYEKVPLPNSVF SYK 12709437
LTP
1.00
- -
0.70
- medium

Substrate: Shc ( Adaptor molecule)
Seq-ID: P29353 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 349 EEEEEPPDHQYYNDFPGKEPP SYK 9710204
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 350 EEEEPPDHQYYNDFPGKEPPL SYK 9710204
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 427 PGRELFDDPSYVNVQNLDKAR SYK 9710204
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--

Substrate: SLP-76 (Adaptor molecule; involved in T cell AG receptor mediate signaling)
Seq-ID: Q13094 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 113 GGWSSFEEDDYESPNDDQDGE SYK 15388330
LTP
0.99
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.92
- medium
Y 128 DDQDGEDDGDYESPNEEEEAP SYK 15388330
LTP
0.30
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.98
- medium

Substrate: SYK (Spleen tyrosine kinase )
Seq-ID: P43405 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 348 REALPMDTEVYESPYADPEEI SYK 8657103
LTP
0.93
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.59
--
Y 352 PMDTEVYESPYADPEEIRPKE SYK 8657103
LTP
1.00
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.53
--
Y 525 LSKALRADENYYKAQTHGKWP SYK 8657103
LTP
1.00
CBL PTB;
Lck SH2
TyrKc
0.19
1XBA 41.92%
Y 526 SKALRADENYYKAQTHGKWPV SYK 8657103
LTP
1.00
CBL PTB;
Lck SH2
TyrKc
0.17
1XBA 30.57%

Substrate: SYK (Spleen tyrosine kinase )
Seq-ID: P48025 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 130 EDLKENLIREYVKQTWNLQGQ SYK 9820500
LTP
1.00
- -
0.28
--
Y 342 REALPMDTEVYESPYADPEEI SYK 8657103
LTP
1.00
PLCG_group SH2;
VAV1 SH2
-
0.58
--
Y 346 PMDTEVYESPYADPEEIRPKE SYK 8657103
LTP
1.00
PLCG_group SH2 -
0.54
--
Y 358 DPEEIRPKEVYLDRSLLTLED SYK 8657103
LTP
0.16
- -
0.44
1XBA 68.12%
Y 519 LSKALRADENYYKAQTHGKWP SYK 8657103
LTP
1.00
- TyrKc
0.19
1XBA 41.92%
Y 520 SKALRADENYYKAQTHGKWPV SYK 8657103
LTP
1.00
- TyrKc
0.17
1XBA 30.57%

Substrate: TUBA1A (Structural protein)
Seq-ID: P68369 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 432 REDMAALEKDYEEVGVDSVEG SYK 8566014
LTP
0.97
Fyn SH2 -
0.47
1SA0 0.44%

Substrate: TYRO protein tyrosine kinase-binding protein precursor (Cell surface receptor)
Seq-ID: O43914 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 91 KQRITETESPYQELQGQRSDV SYK 9490415
LTP
1.00
- -
0.52
- low
Y 102 QELQGQRSDVYSDLNTQRPYY SYK 9490415
LTP
1.00
- -
0.41
- low

Valid HTML 4.01 Transitional