List of substrates found:

Vav  CD3 epsilon  TUBA1A  Insulin receptor substrate 1  CSFR-1  EPHA4  EPHA8  EPHB2  EPHB3  CD3 zeta  c-kit  FAK  ZAP70  CBL E3 ubiquitin protein ligase  P130Cas  FYN  PYK2  PDGF-R beta  CD95 antigen  Grb10  Dystroglycan  Src 


Substrate: Vav (Adaptor molecule. GDP/GTP exchange factor in Rho/Rac molecule)
Seq-ID: P15498 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-17467   CRK_HUMAN
MINT-2837376   PLCG1_BOVIN
MINT-4549720   3BP2_HUMAN
MINT-6743318   RAC1_HUMAN
MINT-6743347   RHOA_HUMAN
MINT-6743356   CDC42_HUMAN
MINT-7226634   ITB2_HUMAN
MINT-7226674   ABL1_HUMAN
MINT-7300569   KHDR1_MOUSE
MINT-7300587   KHDR1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
metal ion binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 plasma membrane,
cytosol		 induction of apoptosis by extracellular signals,
apoptosis,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 174 ENEEAEGDEIYEDLMRSEPVS - 898671
LTP
1.00
 Fyn SH2;
PTPN6 SH2		 -
0.54
 - medium
Y 174 ENEEAEGDEIYEDLMRSEPVS - 10669745
LTP
1.00
 Fyn SH2;
PTPN6 SH2		 -
0.54
 - medium

Substrate: CD3 epsilon (T cell surface glycoprotein)
Seq-ID: P07766 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-7213943   NCK2_HUMAN
MINT-7214058   EPS8_HUMAN
MINT-7214076   ES8L2_HUMAN
MINT-7214253   ES8L1_HUMAN
MINT-7234008   NCK1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
T cell receptor binding,
protein heterodimerization activity,
protein kinase binding,
receptor signaling complex scaffold activity,
transmembrane receptor activity,
receptor signaling protein activity		 external side of plasma membrane,
integral to plasma membrane		 signal complex assembly,
G-protein coupled receptor protein signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 188 ERPPPVPNPDYEPIRKGQRDL - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.67
 - medium
Y 188 ERPPPVPNPDYEPIRKGQRDL - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.67
 - medium
Y 188 ERPPPVPNPDYEPIRKGQRDL - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.67
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 12522270
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15144186
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 18083107
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium

Substrate: TUBA1A (Structural protein)
Seq-ID: P68369 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
GTPase activity,
GTP binding,
structural molecule activity		 microtubule protein polymerization,
microtubule-based movement
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 432 REDMAALEKDYEEVGVDSVEG SYK 8566014
LTP
0.97
 Fyn SH2 -
0.47
 1SA0 0.44%

Substrate: Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)
Seq-ID: P35568 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19010   INSR_HUMAN
MINT-68735   P85A_HUMAN
MINT-74551   EGFR_HUMAN
MINT-74553   ERBB2_HUMAN
MINT-3975430   1433S_HUMAN
MINT-6628637   LT_SV40
MINT-6793745   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoinositide 3-kinase binding,
protein kinase C binding,
insulin-like growth factor receptor binding,
insulin receptor binding,
transmembrane receptor protein tyrosine kinase docking protein activity,
SH2 domain binding		 microsome,
caveola,
cytosol,
insulin receptor complex,
nucleus		 negative regulation of insulin receptor signaling pathway,
glucose homeostasis,
positive regulation of insulin receptor signaling pathway,
positive regulation of fatty acid beta-oxidation,
phosphoinositide 3-kinase cascade,
negative regulation of insulin secretion,
positive regulation of glycogen biosynthetic process,
insulin receptor signaling pathway,
positive regulation of glucose import,
positive regulation of phosphoinositide 3-kinase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 662 RHPQRVDPNGYMMMSPSGGCS - 15592455
HTP
1.00
 Fyn SH2;
MATK SH2;
PIK3R1 SH2;
PTPN11 SH2		 -
0.77
 --

Substrate: CSFR-1 (Macrophage colony stimulating factor I receptor)
Seq-ID: P07333 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
macrophage colony-stimulating factor receptor activity,
protein homodimerization activity,
ATP binding,
cytokine binding		 receptor complex,
integral to plasma membrane		 protein amino acid phosphorylation,
transmembrane receptor protein tyrosine kinase signaling pathway,
multicellular organismal development,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 561 KIIESYEGNSYTFIDPTQLPY CSF1R 15297464
LTP
1.00
 Fyn SH2;
Src SH2;
YES1 SH2		 -
0.14
 - low
Y 809 LARDIMNDSNYIVKGNARLPV CSF1R N.N.
LTP
1.00
 Fyn SH2;
Src SH2;
YES1 SH2		 TyrKc
0.15
 - low
Y 809 LARDIMNDSNYIVKGNARLPV CSF1R 15297464
LTP
1.00
 Fyn SH2;
Src SH2;
YES1 SH2		 TyrKc
0.15
 - low
Y 809 LARDIMNDSNYIVKGNARLPV - 7579387
LTP
1.00
 Fyn SH2;
Src SH2;
YES1 SH2		 TyrKc
0.15
 - low

Substrate: EPHA4 (Receptor for member of the ephrinA family)
Seq-ID: P54764 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ephrin receptor activity,
ATP binding,
protein binding		 integral to plasma membrane protein amino acid phosphorylation,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 602 GVRTYVDPFTYEDPNQAVREF EphA4 8622893
LTP
1.00
 Fyn SH2 -
0.31
 --

Substrate: EPHA8 (Receptor for member of the ephrinA family)
Seq-ID: P29322 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ephrin receptor activity,
ATP binding,
protein binding		 integral to plasma membrane protein amino acid phosphorylation,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 616 EPQFYAEPHTYEEPGRAGRSF EphA8 10498895
LTP
1.00
 Fyn SH2 -
0.51
 - medium

Substrate: EPHB2 (Receptor for member of the ephrinB family)
Seq-ID: P54763 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-3388251   EPHA4_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transmembrane-ephrin receptor activity,
axon guidance receptor activity,
ATP binding,
receptor binding		 neuronal cell body,
integral to plasma membrane,
synapse		 negative regulation of axonogenesis,
retinal ganglion cell axon guidance,
positive regulation of long-term neuronal synaptic plasticity,
ephrin receptor signaling pathway,
learning,
camera-type eye morphogenesis,
central nervous system projection neuron axonogenesis,
peptidyl-tyrosine phosphorylation,
optic nerve morphogenesis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 610 GMKIYIDPFTYEDPNEAVREF EphB2 8622893
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%
Y 610 GMKIYIDPFTYEDPNEAVREF EphB2 10572014
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%
Y 610 GMKIYIDPFTYEDPNEAVREF - 9233798
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%
Y 610 GMKIYIDPFTYEDPNEAVREF EphB2 9632142
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%

Substrate: EPHB3 (Receptor for member of the ephrinB family)
Seq-ID: P54753 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-58214   AFAD_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ephrin receptor activity,
ATP binding,
protein binding		 integral to plasma membrane protein amino acid phosphorylation,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 614 GMKVYIDPFTYEDPNEAVREF EphB3 9674711
LTP
1.00
 CRK SH2;
Fyn SH2;
RASA_group SH2		 -
0.26
 - low

Substrate: CD3 zeta (T-cell surface glycoprotein CD3 zeta chain precursor (from PhosphoBase))
Seq-ID: P20963 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-60782   LCK_HUMAN
MINT-7301967   NCK1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
transmembrane receptor activity		 cytoplasm,
integral to membrane		 interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 72 PAYQQGQNQLYNELNLGRREE - 15144186
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.44
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 12522270
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 83 NELNLGRREEYDVLDKRRGRD - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.47
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE Fyn 8578591
LTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 12522270
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15144186
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15592455
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 16094384
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15659558
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 18083107
HTP
1.00
 LIG_TYR_ITAM
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.63
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 12522270
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 153 QGLSTATKDTYDALHMQALPP - 16094384
HTP
0.90
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium
Y 153 QGLSTATKDTYDALHMQALPP - 15659558
HTP
0.90
 Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.65
 - medium

Substrate: c-kit (Receptor tyrosine kinase)
Seq-ID: P10721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor signaling protein tyrosine kinase activity,
ATP binding,
protein binding		 integral to membrane,
extracellular space		 male gonad development,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 568 KVVEEINGNNYVYIDPTQLPY Kit 9799234
LTP
1.00
 Fyn SH2;
MATK SH2;
PTPN11 SH2;
PTPN6 SH2;
SHC1 SH2		 -
0.13
 --
Y 570 VEEINGNNYVYIDPTQLPYDH Kit 9799234
LTP
1.00
 Fyn SH2;
MATK SH2;
PTPN6 SH2;
SHC1 SH2		 -
0.13
 --

Substrate: FAK (Focal adhesion kinase)
Seq-ID: Q05397 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-17602   LYN_HUMAN
MINT-74938   BCAR1_HUMAN
MINT-3381308   SRC_HUMAN
MINT-6794892   PTN1_HUMAN
MINT-7294020   P53_HUMAN
MINT-7385708   SRC_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
SH2 domain binding,
signal transducer activity		 focal adhesion,
cytosol,
cytoskeleton		 signal complex assembly,
integrin-mediated signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 397 HAVSVSETDDYAEIIDEEDTY FAK 7509446
LTP
1.00
 Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2		 -
0.49
 --
Y 397 HAVSVSETDDYAEIIDEEDTY - 17192257
HTP
1.00
 Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2		 -
0.49
 --
Y 397 HAVSVSETDDYAEIIDEEDTY - 18083107
HTP
1.00
 Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2		 -
0.49
 --

Substrate: ZAP70 (Cytoplasmic tyrosine kinase)
Seq-ID: P43403 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-59476   LCK_HUMAN
MINT-60980   SHC1_HUMAN
MINT-74806   ERBB3_HUMAN
MINT-74807   EGFR_HUMAN
MINT-3374106   HS90A_HUMAN
MINT-3382488   LAT_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
non-membrane spanning protein tyrosine kinase activity,
ATP binding		 cytosol,
T cell receptor complex		 positive thymic T cell selection,
immune response,
intracellular protein kinase cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 492 LSKALGADDSYYTARSAGKWP Lck 8756661
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 8756661
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP Lck 7961936
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 7961936
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP Lck 7642520
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 7642520
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP - 12522270
HTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP - 15592455
HTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP Lck 11270871
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 11270871
LTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP - 16094384
HTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP - 15659558
HTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP - 17192257
HTP
1.00
 Fyn SH2 TyrKc
0.14
 1U59 13.10%
Y 493 SKALGADDSYYTARSAGKWPL Lck 8756661
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 8756661
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL Lck 7961936
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 7961936
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL Lck 7642520
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 7642520
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL - 12522270
HTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL - 15144186
HTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL - 15592455
HTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL Lck 11270871
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 11270871
LTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL - 16094384
HTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL - 15659558
HTP
1.00
 Fyn SH2 TyrKc
0.13
 1U59 68.12%

Substrate: CBL E3 ubiquitin protein ligase (Adaptor molecule)
Seq-ID: P22681 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15516   LCK_HUMAN
MINT-15716   CRK_HUMAN
MINT-16022   CD2AP_HUMAN
MINT-16347   LYN_HUMAN
MINT-16846   LCP2_HUMAN
MINT-17062   FCGR1_HUMAN
MINT-17932   NCK1_HUMAN
MINT-50666   FYN_HUMAN
MINT-50717   ABL1_HUMAN
MINT-50722   CRKL_HUMAN
MINT-58331   ITCH_HUMAN
MINT-60970   RET_HUMAN
MINT-60973   EGFR_HUMAN
MINT-60978   SHC1_HUMAN
MINT-68500   P85A_HUMAN
MINT-2837344   PLCG1_BOVIN
MINT-4299918   ASAP1_HUMAN
MINT-6169713   SPY1_HUMAN
MINT-6170244   SH3G2_HUMAN
MINT-6538940   SPY4_HUMAN
MINT-6538977   KSYK_HUMAN
MINT-6539587   MET_HUMAN
MINT-6539601   SPY2_HUMAN
MINT-6539646   VGFR1_HUMAN
MINT-6539679   RON_HUMAN
MINT-6539730   SRC_HUMAN
MINT-7040249   GRB2_HUMAN
MINT-7046364   ITSN1_HUMAN
MINT-7103623   MK08_HUMAN
MINT-7211864   ARHG7_HUMAN
MINT-7214822   FYN_MOUSE
MINT-7218352   SH3K1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
calcium ion binding,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
signal transducer activity,
ubiquitin-protein ligase activity		 cytosol,
nucleus		 epidermal growth factor receptor signaling pathway,
positive regulation of receptor-mediated endocytosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 552 LPPPPPPDRPYSVGAESRPQR - 15951569
HTP
0.04
 Fyn SH2;
GRB2 SH2		 -
0.94
 --

Substrate: P130Cas (Adaptor molecule. Contain 15 YxxP motifs. )
Seq-ID: P56945 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-74936   PTN12_HUMAN
MINT-74938   FAK1_HUMAN
MINT-3974941   1433S_HUMAN
MINT-6174734   ACTB_HUMAN
MINT-6763936   CRK_HUMAN
MINT-6793484   PTN1_HUMAN
MINT-7104353   CDC42_HUMAN
MINT-7104422   SRC_HUMAN
MINT-7104436   ACK1_HUMAN
MINT-7247002   FYN_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
protein kinase binding,
protein phosphatase binding,
signal transducer activity		 focal adhesion,
membrane fraction,
cytosol,
ruffle		 regulation of cell growth,
B cell receptor signaling pathway,
cell division,
positive regulation of cell migration,
nerve growth factor receptor signaling pathway,
cell migration,
integrin-mediated signaling pathway,
epidermal growth factor receptor signaling pathway,
actin filament organization,
regulation of apoptosis,
platelet-derived growth factor receptor signaling pathway,
T cell receptor signaling pathway,
cell adhesion,
insulin receptor signaling pathway,
cell proliferation,
G-protein coupled receptor protein signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 664 ENSEGGWMEDYDYVHLQGKEE - 8621540
LTP
1.00
 FES SH2;
Fyn SH2;
Lck SH2;
Src SH2		 -
0.49
 - medium
Y 664 ENSEGGWMEDYDYVHLQGKEE - 11604500
LTP
1.00
 FES SH2;
Fyn SH2;
Lck SH2;
Src SH2		 -
0.49
 - medium

Substrate: FYN (Cytoplasmic tyrosine kinase)
Seq-ID: P06241 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14847   WASP_HUMAN
MINT-15132   HNRPK_RAT
MINT-15408   KHDR1_HUMAN
MINT-15425   SHC1_HUMAN
MINT-16566   FYB_HUMAN
MINT-46000   CTNB1_MOUSE
MINT-50377   RASH_HUMAN
MINT-50652   MAP2_HUMAN
MINT-50666   CBL_HUMAN
MINT-61277   G3BP1_HUMAN
MINT-61574   CTNB1_RAT
MINT-2792095   PAK2_HUMAN
MINT-2792412   ADA15_HUMAN
MINT-2859062   ATX1_HUMAN
MINT-3381335   VGFR2_HUMAN
MINT-3381360   SRC_HUMAN
MINT-3381384   NCK1_HUMAN
MINT-4085360   TNR6_HUMAN
MINT-7214580   5HT6R_HUMAN
MINT-7245838   TRI39_HUMAN
MINT-7245886   ORC1_HUMAN
MINT-7245898   AKAP6_HUMAN
MINT-7245910   CENPA_HUMAN
MINT-7245922   LRBA_HUMAN
MINT-7245934   TRAIP_HUMAN
MINT-7245958   RPP38_HUMAN
MINT-7245970   HCN2_HUMAN
MINT-7246030   ASAP2_HUMAN
MINT-7246102   SYNJ2_HUMAN
MINT-7246150   RIMS1_HUMAN
MINT-7246210   DLGP4_HUMAN
MINT-7246222   LAP2B_HUMAN
MINT-7246246   TGON2_HUMAN
MINT-7246270   EPS15_HUMAN
MINT-7246306   CD2AP_HUMAN
MINT-7246318   MLL4_HUMAN
MINT-7246402   ARHGB_HUMAN
MINT-7246426   FLNC_HUMAN
MINT-7246450   SP1_HUMAN
MINT-7246474   RIMS2_HUMAN
MINT-7246522   ABL1_HUMAN
MINT-7246534   SNX12_HUMAN
MINT-7246558   M4K1_HUMAN
MINT-7246570   PRIC3_HUMAN
MINT-7246594   WNK2_HUMAN
MINT-7246630   RTN4_HUMAN
MINT-7246666   SF3B4_HUMAN
MINT-7246678   NFASC_HUMAN
MINT-7246714   GCF_HUMAN
MINT-7246726   PPR3D_HUMAN
MINT-7246750   BAZ2A_HUMAN
MINT-7246774   KI67_HUMAN
MINT-7246798   DDX41_HUMAN
MINT-7246810   DPOD1_HUMAN
MINT-7246834   FLNA_HUMAN
MINT-7246846   CDC27_HUMAN
MINT-7246870   SNX8_HUMAN
MINT-7246882   ABL2_HUMAN
MINT-7246918   ASAP1_HUMAN
MINT-7246930   MED14_HUMAN
MINT-7246954   WIPF1_HUMAN
MINT-7246978   E41L3_HUMAN
MINT-7247002   BCAR1_HUMAN
MINT-7247014   MYPT1_HUMAN
MINT-7247038   CAF1A_HUMAN
MINT-7247050   SHRM2_HUMAN
MINT-7247074   VP13A_HUMAN
MINT-7247086   CDKL5_HUMAN
MINT-7247098   ICAL_HUMAN
MINT-7247122   RRAS_HUMAN
MINT-7247134   NELFB_HUMAN
MINT-7247146   SPN90_HUMAN
MINT-7247158   CKAP5_HUMAN
MINT-7247170   FANCA_HUMAN
MINT-7247182   HDAC6_HUMAN
MINT-7247194   SNX3_HUMAN
MINT-7247206   BRPF3_HUMAN
MINT-7247230   XRCC1_HUMAN
MINT-7247242   DAB2_HUMAN
MINT-7247254   M4K5_HUMAN
MINT-7247290   STF1_HUMAN
MINT-7247302   DOCK1_HUMAN
MINT-7247350   BRCA2_HUMAN
MINT-7247374   RPGF1_HUMAN
MINT-7247422   DAG1_HUMAN
MINT-7247434   SUV92_HUMAN
MINT-7247446   FCG2B_HUMAN
MINT-7247458   FCG2C_HUMAN
MINT-7247482   CELR3_HUMAN
MINT-7247530   SOS1_HUMAN
MINT-7247554   MOS_HUMAN
MINT-7247566   SNX17_HUMAN
MINT-7306611   LCP2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
metal ion binding,
glycoprotein binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding		 plasma membrane,
endosome,
cytosol		 learning,
feeding behavior,
calcium ion transport,
interspecies interaction between organisms,
T cell receptor signaling pathway,
intracellular protein kinase cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 531 EDYFTATEPQYQPGENL     Csk 1985196
LTP
0.94
 MOD_TYR_CSK
 Fyn SH2;
Src SH2		 -
0.42
 --

Substrate: PYK2 (Focal adhesion kinase 2)
Seq-ID: Q14289 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-68515   PDC6I_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
signal transducer activity		 positive regulation of cell proliferation,
signal complex assembly,
apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 402 SESCSIESDIYAEIPDETLRR SYK 8816475
LTP
1.00
 Fyn SH2;
MATK SH2;
Src SH2		 -
0.37
 --
Y 402 SESCSIESDIYAEIPDETLRR - 9560226
LTP
1.00
 Fyn SH2;
MATK SH2;
Src SH2		 -
0.37
 --
Y 402 SESCSIESDIYAEIPDETLRR PYK2 15105428
LTP
1.00
 Fyn SH2;
MATK SH2;
Src SH2		 -
0.37
 --

Substrate: PDGF-R beta (Beta platelet-derived growth factor receptor)
Seq-ID: P09619 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-2832596   NHRF2_HUMAN
MINT-2832984   PTEN_HUMAN
MINT-2833042   NHRF1_HUMAN
MINT-6762380   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
vascular endothelial growth factor receptor activity,
platelet-derived growth factor binding,
platelet activating factor receptor activity,
platelet-derived growth factor receptor binding,
ATP binding,
platelet-derived growth factor beta-receptor activity		 integral to plasma membrane positive regulation of cell proliferation,
positive regulation of cell migration,
protein amino acid autophosphorylation,
peptidyl-tyrosine phosphorylation,
cell chemotaxis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 579 IESVSSDGHEYIYVDPMQLPY PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
SLA SH2;
Src SH2;
STAT5 SH2;
YES1 SH2		 -
0.15
 - medium
Y 581 SVSSDGHEYIYVDPMQLPYDS PDGFR_beta 8617789
LTP
1.00
 Fyn SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2;
RASA_group SH2;
SLA SH2;
Src SH2;
STAT5 SH2;
YES1 SH2		 -
0.16
 - medium
Y 740 VSLTGESDGGYMDMSKDESVD PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2		 TyrKc
0.45
 - medium
Y 751 MDMSKDESVDYVPMLDMKGDV PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
Src SH2		 TyrKc
0.29
 - medium
Y 751 MDMSKDESVDYVPMLDMKGDV PDGFR_group 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
Src SH2		 TyrKc
0.29
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_beta 10821867
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_group 10821867
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_beta 2550144
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_group 2550144
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium

Substrate: CD95 antigen (Cell surface receptor)
Seq-ID: P25445 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-18737   FADD_HUMAN
MINT-4055317   CASP8_HUMAN
MINT-4085360   FYN_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
transmembrane receptor activity,
kinase binding		 extracellular region,
death-inducing signaling complex,
cytosol,
integral to membrane,
soluble fraction		 positive regulation of necrotic cell death,
induction of apoptosis by extracellular signals,
protein complex assembly,
anti-apoptosis,
immune response,
activation of pro-apoptotic gene products
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 291 WHQLHGKKEAYDTLIKDLKKA - 17195092
LTP
0.97
 Fyn SH2;
INPP5D SH2		 DEATH
0.33
 3EZQ 62.45%
Y 291 WHQLHGKKEAYDTLIKDLKKA - 15660394
LTP
0.97
 Fyn SH2;
INPP5D SH2		 DEATH
0.33
 3EZQ 62.45%

Substrate: Grb10 (Adapter molecule)
Seq-ID: Q13322 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15644   IGF1R_HUMAN
MINT-16516   INSR_HUMAN
MINT-16802   EGFR_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin receptor binding,
SH3/SH2 adaptor activity		 plasma membrane,
cytoplasm		 negative regulation of glycogen biosynthetic process,
negative regulation of insulin receptor signaling pathway,
negative regulation of glucose import,
positive regulation of vascular endothelial growth factor receptor signaling pathway,
negative regulation of Wnt receptor signaling pathway,
insulin receptor signaling pathway,
positive regulation of phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 67 NDMNASLESLYSACSMQSDTV Fyn 10871840
LTP
0.81
 Fyn SH2;
Src SH2		 -
0.50
 - low
Y 67 NDMNASLESLYSACSMQSDTV SRC 10871840
LTP
0.81
 Fyn SH2;
Src SH2		 -
0.50
 - low

Substrate: Dystroglycan (Adhesion molecule)
Seq-ID: Q14118 [Homo sapiens]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-18977   UTRO_HUMAN
MINT-7245682   SRC_HUMAN
MINT-7247422   FYN_HUMAN
MINT-7249366   NCK1_HUMAN
MINT-7251982   P85A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
calcium ion binding,
structural constituent of muscle,
laminin-1 binding,
vinculin binding,
actin binding,
alpha-actinin binding,
tubulin binding		 filopodium,
basement membrane,
integral to membrane of membrane fraction,
lamellipodium,
cytoskeleton,
integral to membrane,
extracellular space,
nucleoplasm,
contractile ring		 negative regulation of MAPKKK cascade,
microtubule anchoring,
negative regulation of cell migration,
cytoskeletal anchoring at plasma membrane,
negative regulation of protein kinase B signaling cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 892 NMTPYRSPPPYVPP        SRC 12795607
LTP
1.00
 Csk SH2;
Fyn SH2;
NCK SH2;
Src SH2		 DAG1
0.77
 - medium

Substrate: Src (Proto-oncogene tyrosine-protein kinase Src)
Seq-ID: P12931 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14765   DDR2_HUMAN
MINT-15459   CAV1_HUMAN
MINT-46002   CTNB1_MOUSE
MINT-50376   RASH_HUMAN
MINT-62340   KPCD_HUMAN
MINT-62342   CDCP1_HUMAN
MINT-65953   DYN1_HUMAN
MINT-65954   DYN2_HUMAN
MINT-68512   PDC6I_HUMAN
MINT-74753   ERBB3_HUMAN
MINT-2792760   PAK2_HUMAN
MINT-2793013   ADA15_HUMAN
MINT-2840132   TLR3_HUMAN
MINT-3381308   FAK1_HUMAN
MINT-3381360   FYN_HUMAN
MINT-4051815   ADRB2_HUMAN
MINT-4961196   AFAD_HUMAN
MINT-4980122   SNIP_MOUSE
MINT-5210599   SNIP_HUMAN
MINT-6539730   CBL_HUMAN
MINT-6771405   FAK1_MOUSE
MINT-6794909   ACTS_HUMAN
MINT-6795322   ACTN1_HUMAN
MINT-6795447   PTN1_HUMAN
MINT-7035260   HNRPK_HUMAN
MINT-7040283   CBLB_HUMAN
MINT-7104422   BCAR1_HUMAN
MINT-7145938   RL10_HUMAN
MINT-7244986   ASAP1_HUMAN
MINT-7244998   FANCA_HUMAN
MINT-7245022   PHAR2_HUMAN
MINT-7245034   ABL1_HUMAN
MINT-7245058   DLGP4_HUMAN
MINT-7245070   SNX17_HUMAN
MINT-7245106   RTN4_HUMAN
MINT-7245118   ASAP2_HUMAN
MINT-7245142   E41L3_HUMAN
MINT-7245154   ICAL_HUMAN
MINT-7245214   FCG2B_HUMAN
MINT-7245226   FCG2C_HUMAN
MINT-7245334   SHAN2_HUMAN
MINT-7245346   SHRM2_HUMAN
MINT-7245358   DNLI3_HUMAN
MINT-7245370   EIF3D_HUMAN
MINT-7245406   HCN2_HUMAN
MINT-7245490   CKAP5_HUMAN
MINT-7245502   M4K1_HUMAN
MINT-7245538   RPP38_HUMAN
MINT-7245562   SP1_HUMAN
MINT-7245574   DOCK1_HUMAN
MINT-7245586   RLGPB_HUMAN
MINT-7245598   ABL2_HUMAN
MINT-7245610   CELR2_HUMAN
MINT-7245622   SOS1_HUMAN
MINT-7245634   AKAP6_HUMAN
MINT-7245670   DPOD1_HUMAN
MINT-7245682   DAG1_HUMAN
MINT-7245694   SNX3_HUMAN
MINT-7245730   KI67_HUMAN
MINT-7245742   CD97_HUMAN
MINT-7245754   RPGF1_HUMAN
MINT-7245778   ACAP1_HUMAN
MINT-7245790   PRIC3_HUMAN
MINT-7245814   AKAP2_HUMAN
MINT-7245826   RRAS_HUMAN
MINT-7296136   P85A_HUMAN
MINT-7296149   ACTB_HUMAN
MINT-7306598   LCP2_HUMAN
MINT-7552515   PTPRA_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3/SH2 adaptor activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
integrin binding,
SH2 domain binding		 caveola,
cytosol		 protein amino acid phosphorylation,
regulation of bone resorption,
signal complex assembly,
regulation of vascular permeability,
response to interleukin-1,
interspecies interaction between organisms,
Ras protein signal transduction,
positive regulation of integrin activation,
intracellular protein kinase cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 530 EDYFTSTEPQYQPGENL     - 3103926
LTP
0.94
 MOD_TYR_CSK
 Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2		 -
0.46
 1FMK 18.34%
Y 530 EDYFTSTEPQYQPGENL     Csk 12468645
LTP
0.94
 MOD_TYR_CSK
 Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2		 -
0.46
 1FMK 18.34%
Y 530 EDYFTSTEPQYQPGENL     - 12387813
LTP
0.94
 MOD_TYR_CSK
 Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2		 -
0.46
 1FMK 18.34%

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