List of substrates found:

Histone deacetylase 4  Raf1  HDAC7A  Integrin beta 2  Forkhead box protein O1A  WEE 1 tyrosine kinase  BAD  Pde3a  Cytokeratin 18  PDK1  Orphan nuclear receptor NR4A1  RIN1  cdc25c  PCTAIRE1  MAP3K5  HDAC5  p53  cdc25B  Kinase suppressor of ras-1 


Substrate: Histone deacetylase 4 (Enzyme: Deacetylase)
Seq-ID: P56524 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 246 KDDFPLRKTASEPNLKLRSRL - 10958686
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.64
- low
S 246 KDDFPLRKTASEPNLKLRSRL - 10869435
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.64
- low
S 467 RQHRPLGRTQSAPLPQNAQAL CaM-KIV 11470791
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.84
- low
S 467 RQHRPLGRTQSAPLPQNAQAL - 18669648
HTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.84
- low
S 632 GGHRPLSRAQSSPASATFPVS CaM-KIV 11470791
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.67
- low
S 632 GGHRPLSRAQSSPASATFPVS - 18669648
HTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.67
- low

Substrate: Raf1 (RAF proto-oncogene serine/threonine-protein kinase)
Seq-ID: P04049 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 259 GSLSQRQRSTSTPNVHMVSTT PKA_group 11971957
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.73
- medium
S 259 GSLSQRQRSTSTPNVHMVSTT PKB_group 10576742
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.73
- medium
S 259 GSLSQRQRSTSTPNVHMVSTT - 12801936
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.73
- medium
S 259 GSLSQRQRSTSTPNVHMVSTT - 18220336
HTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.73
- medium
S 259 GSLSQRQRSTSTPNVHMVSTT - 18669648
HTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.73
- medium
S 621 HSLPKINRSASEPSLHRAAHT PKA_group 11971957
LTP
0.99
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.49
- medium
S 621 HSLPKINRSASEPSLHRAAHT - 9091312
LTP
0.99
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.49
- medium

Substrate: HDAC7A (Enzyme: Deacetylase)
Seq-ID: Q8WUI4 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 15623513
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.63
- medium
S 155 PEHFPLRKTVSEPNLKLRYKP MARK_group 16980613
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.63
- medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18617643
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.63
- medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18509061
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.63
- medium

Substrate: Integrin beta 2 (Adhesion molecule)
Seq-ID: P05107 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 758 NNDNPLFKSATTTVMNPKFAE PKC_group 11700305
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Integrin_b_cyt
0.35
2JF1 93.15%
T 758 NNDNPLFKSATTTVMNPKFAE PKC_alpha 11700305
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Integrin_b_cyt
0.35
2JF1 93.15%
T 758 NNDNPLFKSATTTVMNPKFAE PKC_delta 11700305
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Integrin_b_cyt
0.35
2JF1 93.15%
T 758 NNDNPLFKSATTTVMNPKFAE PKC_eta 11700305
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Integrin_b_cyt
0.35
2JF1 93.15%
T 758 NNDNPLFKSATTTVMNPKFAE - 12682249
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Integrin_b_cyt
0.35
2JF1 93.15%

Substrate: Forkhead box protein O1A (Forkhead box protein O1A)
Seq-ID: Q12778 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 24 FEPLPRPRSCTWPLPRPEFSQ PKB_group 10358014
LTP
1.00
MOD_PKB_1
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAZ 14-3-3
-
0.70
- medium
T 24 FEPLPRPRSCTWPLPRPEFSQ SGK_group 11410590
LTP
1.00
MOD_PKB_1
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAZ 14-3-3
-
0.70
- medium
T 24 FEPLPRPRSCTWPLPRPEFSQ PKB_group 10358075
LTP
1.00
MOD_PKB_1
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAZ 14-3-3
-
0.70
- medium

Substrate: WEE 1 tyrosine kinase (Dual specificity kinase)
Seq-ID: P30291 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 642 LIGKKMNRSVSLTIY       - 15150265
LTP
0.98
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.28
- medium
S 642 LIGKKMNRSVSLTIY       - 15964826
LTP
0.98
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.28
- medium

Substrate: BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))
Seq-ID: Q61337 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 9381178
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 10949026
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 112 GAMETRSRHSSYPAGTEEDEG - 15849194
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 112 GAMETRSRHSSYPAGTEEDEG RSK_group 10880354
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 112 GAMETRSRHSSYPAGTEEDEG - 17242355
HTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 112 GAMETRSRHSSYPAGTEEDEG RSK_group 16103085
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 11983683
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.88
- medium
S 136 ELSPFRGRSRSAPPNLWAAQR PKB_group 9381178
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.66
- medium
S 136 ELSPFRGRSRSAPPNLWAAQR PKB_group 10949026
LTP
1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.66
- medium
S 155 QRYGRELRRMSDEFEGSFKGL RSK_group 10837486
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.60
- medium
S 155 QRYGRELRRMSDEFEGSFKGL - 10837473
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.60
- medium
S 155 QRYGRELRRMSDEFEGSFKGL - 15123689
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.60
- medium
S 155 QRYGRELRRMSDEFEGSFKGL RSK_group 10880354
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
Bcl-2_BAD
0.60
- medium

Substrate: Pde3a (Enzyme Pphosphodiesterase)
Seq-ID: Q14432 [Homo sapiens]
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 428 KLAIPKRLRRSLPPGLLRRVS - 16964243
HTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.49
- medium
S 428 KLAIPKRLRRSLPPGLLRRVS - 18669648
HTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.49
- medium

Substrate: Cytokeratin 18 (Structural protein)
Seq-ID: P05783 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 34 YGARPVSSAASVYAGAGGSGS - 9524113
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.45
- low
S 34 YGARPVSSAASVYAGAGGSGS - 16083285
HTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.45
- low

Substrate: PDK1 (3-phosphoinositide dependent protein kinase-1; serine/threonine kinase)
Seq-ID: O15530 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 241 SPESKQARANSFVGTAQYVSP PDK-1 10455013
LTP
1.00
YWHAH 14-3-3;
YWHAQ 14-3-3
S_TKc
0.25
1UU3 123.77%
S 241 SPESKQARANSFVGTAQYVSP - 15302935
HTP
1.00
YWHAH 14-3-3;
YWHAQ 14-3-3
S_TKc
0.25
1UU3 123.77%
S 241 SPESKQARANSFVGTAQYVSP - 18669648
HTP
1.00
YWHAH 14-3-3;
YWHAQ 14-3-3
S_TKc
0.25
1UU3 123.77%

Substrate: Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR (Early response protein NAK1) (TR3 orphan receptor))
Seq-ID: P12813 [Mus musculus]
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 354 SLKGRRGRLPSKPKQPPDASP - 9322922
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.77
1CIT 100.82%

Substrate: RIN1 (Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation)
Seq-ID: Q13671 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 351 GRRRPLLRSMSAAFCSLLAPE PKD1 11784866
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.38
- low
S 351 GRRRPLLRSMSAAFCSLLAPE - 18669648
HTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.38
- low

Substrate: cdc25c (M-phase inducer phosphatase 3)
Seq-ID: P30307 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 216 VSRSGLYRSPSMPENLNRPRL CHK2 10744722
LTP
0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
M-inducer_phosp
0.66
- low
S 216 VSRSGLYRSPSMPENLNRPRL - 15629715
LTP
0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
M-inducer_phosp
0.66
- low
S 216 VSRSGLYRSPSMPENLNRPRL CHK2 9836640
LTP
0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
M-inducer_phosp
0.66
- low
S 216 VSRSGLYRSPSMPENLNRPRL BRSK1 9543386
LTP
0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
M-inducer_phosp
0.66
- low

Substrate: PCTAIRE1 (Serine/threonine-protein kinase PCTAIRE-1)
Seq-ID: Q00536 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 119 ISTEDINKRLSLPADIRLPEG PKA_group 12154078
LTP
0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.47
- medium
S 119 ISTEDINKRLSLPADIRLPEG - 17192257
HTP
0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.47
- medium
S 153 KPLSRRLRRVSLSEIGFGKLE PKA_group 12154078
LTP
0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.23
- medium
S 153 KPLSRRLRRVSLSEIGFGKLE - 17192257
HTP
0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.23
- medium
S 153 KPLSRRLRRVSLSEIGFGKLE - 18669648
HTP
0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.23
- medium

Substrate: MAP3K5 (Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.1. -) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1)
Seq-ID: Q99683 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 966 AGSNEYLRSISLPVPVLVEDT MAP3K5 10411906
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.33
--

Substrate: HDAC5 (histone deacetylase activity, specific transcriptional repressor activity)
Seq-ID: Q9UQL6 [Homo sapiens]
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 259 RDDFPLRKTASEPNLKVRSRL CaM-KIV 11081517
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.69
- medium
S 498 PRHRPLSRTQSSPLPQSPQAL CaM-KIV 11081517
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.88
- medium

Substrate: p53 (Cellular tumor antigen p53)
Seq-ID: P04637 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-13742   CHK2_HUMAN
MINT-15878   UBP7_HUMAN
MINT-16161   BRCA1_HUMAN
MINT-16977   PARP1_HUMAN
MINT-19990   PIN1_HUMAN
MINT-24859   ASPP2_HUMAN
MINT-45889   CEBPZ_HUMAN
MINT-49767   ATM_HUMAN
MINT-50577   SAE1_HUMAN
MINT-56524   SP1_HUMAN
MINT-58470   MED1_HUMAN
MINT-58672   HNRL1_HUMAN
MINT-60094   HIPK2_HUMAN
MINT-61312   MK08_HUMAN
MINT-61317   WWOX_HUMAN
MINT-62206   PP1A_HUMAN
MINT-63290   ARI2_HUMAN
MINT-63365   KITH_HUMAN
MINT-63497   ZNF24_HUMAN
MINT-63537   IF2B_HUMAN
MINT-63547   RAB4A_HUMAN
MINT-63559   SAT1_HUMAN
MINT-64119   STX5_HUMAN
MINT-64188   MD2BP_HUMAN
MINT-64748   K0087_HUMAN
MINT-65132   HSPB1_HUMAN
MINT-65272   MPH6_HUMAN
MINT-68565   BMX_HUMAN
MINT-74886   NPM_HUMAN
MINT-74925   1433Z_HUMAN
MINT-1795431   NMT1_HUMAN
MINT-1891378   CDN1A_HUMAN
MINT-1958329   CHK1_HUMAN
MINT-2634790   RGRF1_HUMAN
MINT-2858243   DVL2_HUMAN
MINT-2866927   SCAM1_HUMAN
MINT-3390028   KC1D_RAT
MINT-3979604   P53_MOUSE
MINT-4049689   NR4A1_HUMAN
MINT-4052116   SYVN1_HUMAN
MINT-4052873   GRP78_HUMAN
MINT-4302642   HS71L_HUMAN
MINT-4303978   XPO1_HUMAN
MINT-4329805   TOPRS_HUMAN
MINT-4793180   EGR1_HUMAN
MINT-4793253   GSK3B_HUMAN
MINT-4793489   PML_HUMAN
MINT-5114724   ZN363_HUMAN
MINT-5207405   HDAC8_HUMAN
MINT-6540866   PSME3_HUMAN
MINT-6540889   MDM2_HUMAN
MINT-6628692   LT_SV40
MINT-6665320   CBP_HUMAN
MINT-6701342   MAP1B_HUMAN
MINT-7013631   PA1_HUMAN
MINT-7013916   RYBP_HUMAN
MINT-7103733   ANDR_HUMAN
MINT-7144912   TOE1_HUMAN
MINT-7222784   FRAP_HUMAN
MINT-7263630   EP300_HUMAN
MINT-7266250   PLK1_HUMAN
MINT-7294020   FAK1_HUMAN
MINT-7295816   IKKB_HUMAN
MINT-7557644   GRP75_HUMAN
MINT-7711943   1433S_HUMAN
MINT-7717378   PHB_HUMAN
MINT-7718917   SNAI1_HUMAN
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 376 SSHLKSKKGQSTSRHKKLMFK CDK7 9315650
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.81
--
S 378 HLKSKKGQSTSRHKKLMFKTE CDK7 9315650
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.82
--

Substrate: cdc25B (Dual specificity phosphatase)
Seq-ID: P30305 [Homo sapiens]
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 323 SKCQRLFRSPSMPCSVIRPIL Eg3 kinase 12400006
LTP
1.00
MOD_ProDKin_1
YWHAH 14-3-3 M-inducer_phosp
0.29
- medium
S 323 SKCQRLFRSPSMPCSVIRPIL MAPKAPK2 15629715
LTP
1.00
MOD_ProDKin_1
YWHAH 14-3-3 M-inducer_phosp
0.29
- medium

Substrate: Kinase suppressor of ras-1 (ATP binding)
Seq-ID: Q61097 [Mus musculus]
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 297 PSFPTLTRSKSHESQLGNRID - 9858547
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.59
- medium
S 392 LPLARLRRTESVPSDINNPVD - 9858547
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.61
- medium
S 392 LPLARLRRTESVPSDINNPVD - 12105213
LTP
1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3
-
0.61
- medium


Valid HTML 4.01 Transitional