Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

HDAC7A RIN1 NFATC4 Common beta c subunit MAP3K5 p53 Cyclin dependent kinase inhibitor 1B RGS7 Raf1 PKC mu WEE 1 tyrosine kinase Pde3a Orphan nuclear receptor NR4A1 YAP65 Histone deacetylase 4 PCTAIRE1 Integrin beta 2 BAD Cytokeratin 18 PDK1 cdc25c Kinase suppressor of ras-1 HDAC5

Substrate: HDAC7A (Enzyme: Deacetylase)

Seq-ID: Q8WUI4 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-3296507   1433Z_HUMAN
MINT-3975829   1433S_HUMAN
MINT-6177417   KPCD2_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein kinase C binding,
transcription repressor binding,
histone deacetylase activity histone deacetylase complex,
cytoplasm negative regulation of interleukin-2 production,
chromatin modification,
transcription,
positive regulation of cell migration involved in sprouting angiogenesis,
negative regulation of osteoblast differentiation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 15623513
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.63
- medium

S 155 PEHFPLRKTVSEPNLKLRYKP MARK_group 16980613
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.63
- medium

S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18617643
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.63
- medium

S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18509061
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.63
- medium

Substrate: RIN1 (Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation)

Seq-ID: Q13671 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-13962   1433B_HUMAN
MINT-17571   1433Z_HUMAN
MINT-59456   ABL1_MOUSE
MINT-59459   ABL2_HUMAN
MINT-59464   RASH_HUMAN
MINT-59466   ABL1_HUMAN
MINT-74713   ERBB2_HUMAN
MINT-74714   ERBB3_HUMAN
MINT-7972262   DLG4_RAT

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

GTPase activator activity,
protein binding plasma membrane,
cytoplasm,
cytoskeleton signal transduction,
endocytosis

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 351 GRRRPLLRSMSAAFCSLLAPE PKD1 11784866
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.38
- low

S 351 GRRRPLLRSMSAAFCSLLAPE - 18669648
HTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.38
- low

Substrate: NFATC4 (transcription coactivator activity)

Seq-ID: Q14934 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
MINT-7972976   DLG4_RAT

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

transcription coactivator activity,
sequence-specific DNA binding transcription factor activity cytoplasm,
nucleus transcription from RNA polymerase II promoter,
inflammatory response,
regulation of transcription, DNA-dependent,
cell differentiation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 272 PASPCGKRRYSSSGTPSSASP - 18220336
HTP

1.00
YWHAQ 14-3-3 -
0.75
- -

Substrate: Common beta c subunit (Cytokine recpetor common beta chain)

Seq-ID: P32927 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

cytokine receptor activity granulocyte macrophage colony-stimulating factor receptor complex respiratory gaseous exchange

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 601 GPYLGPPHSRSLPDILGQPEP PKA_group 10949031
LTP

1.00
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.90
- medium

S 601 GPYLGPPHSRSLPDILGQPEP - 16437163
LTP

1.00
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.90
- medium

Substrate: MAP3K5 (Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.1. -) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1)

Seq-ID: Q99683 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-16168   M3K3_HUMAN
MINT-18083   M3K2_HUMAN
MINT-18459   DAB2P_HUMAN
MINT-3391607   MP2K7_HUMAN
MINT-7263196   ARRB2_HUMAN
MINT-7263254   ARRB1_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

magnesium ion binding,
protein homodimerization activity,
ATP binding,
caspase activator activity,
MAP kinase kinase kinase activity induction of apoptosis by extracellular signals,
apoptosis,
activation of JUN kinase activity,
interspecies interaction between organisms

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 966 AGSNEYLRSISLPVPVLVEDT MAP3K5 10411906
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.33
- -

Substrate: p53 (Cellular tumor antigen p53)

Seq-ID: P04637 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-13742   CHK2_HUMAN
MINT-15878   UBP7_HUMAN
MINT-16161   BRCA1_HUMAN
MINT-16977   PARP1_HUMAN
MINT-19990   PIN1_HUMAN
MINT-24859   ASPP2_HUMAN
MINT-45889   CEBPZ_HUMAN
MINT-49767   ATM_HUMAN
MINT-50577   SAE1_HUMAN
MINT-56524   SP1_HUMAN
MINT-58470   MED1_HUMAN
MINT-58672   HNRL1_HUMAN
MINT-60094   HIPK2_HUMAN
MINT-61312   MK08_HUMAN
MINT-61317   WWOX_HUMAN
MINT-62206   PP1A_HUMAN
MINT-63290   ARI2_HUMAN
MINT-63365   KITH_HUMAN
MINT-63497   ZNF24_HUMAN
MINT-63537   IF2B_HUMAN
MINT-63547   RAB4A_HUMAN
MINT-63559   SAT1_HUMAN
MINT-64119   STX5_HUMAN
MINT-64188   MD2BP_HUMAN
MINT-64748   K0087_HUMAN
MINT-65132   HSPB1_HUMAN
MINT-65272   MPH6_HUMAN
MINT-68565   BMX_HUMAN
MINT-74886   NPM_HUMAN
MINT-74925   1433Z_HUMAN
MINT-1795431   NMT1_HUMAN
MINT-1891378   CDN1A_HUMAN
MINT-1958329   CHK1_HUMAN
MINT-2634790   RGRF1_HUMAN
MINT-2858243   DVL2_HUMAN
MINT-2866927   SCAM1_HUMAN
MINT-3390028   KC1D_RAT
MINT-3979604   P53_MOUSE
MINT-4049689   NR4A1_HUMAN
MINT-4052116   SYVN1_HUMAN
MINT-4052873   GRP78_HUMAN
MINT-4302642   HS71L_HUMAN
MINT-4303978   XPO1_HUMAN
MINT-4329805   TOPRS_HUMAN
MINT-4793180   EGR1_HUMAN
MINT-4793253   GSK3B_HUMAN
MINT-4793489   PML_HUMAN
MINT-5114724   ZN363_HUMAN
MINT-5207405   HDAC8_HUMAN
MINT-6540866   PSME3_HUMAN
MINT-6540889   MDM2_HUMAN
MINT-6628692   LT_SV40
MINT-6665320   CBP_HUMAN
MINT-6701342   MAP1B_HUMAN
MINT-7013631   PA1_HUMAN
MINT-7013916   RYBP_HUMAN
MINT-7103733   ANDR_HUMAN
MINT-7144912   TOE1_HUMAN
MINT-7222784   FRAP_HUMAN
MINT-7263630   EP300_HUMAN
MINT-7266250   PLK1_HUMAN
MINT-7294020   FAK1_HUMAN
MINT-7295816   IKKB_HUMAN
MINT-7557644   GRP75_HUMAN
MINT-7711943   1433S_HUMAN
MINT-7717378   PHB_HUMAN
MINT-7718917   SNAI1_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

transcription activator activity,
protease binding,
DNA strand annealing activity,
chromatin binding,
copper ion binding,
ATP binding,
transcription factor binding,
chaperone binding,
zinc ion binding,
histone acetyltransferase binding,
promoter binding,
sequence-specific DNA binding transcription factor activity,
protein N-terminus binding,
protein heterodimerization activity,
protein phosphatase 2A binding,
protein kinase binding,
ubiquitin protein ligase binding nucleolus,
nuclear matrix,
insoluble fraction,
protein complex,
endoplasmic reticulum,
PML body,
mitochondrion positive regulation of gene-specific transcription from RNA polymerase II promoter,
senescence,
mitotic cell cycle G1/S DNA damage checkpoint,
cell cycle arrest,
regulation of mitochondrial membrane permeability,
response to gamma radiation,
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,
response to tumor cell,
ER overload response,
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis,
interspecies interaction between organisms,
Ras protein signal transduction,
nucleotide-excision repair,
protein tetramerization,
cellular response to glucose starvation,
negative regulation of helicase activity,
negative regulation of cell growth,
base-excision repair,
activation of caspase activity by cytochrome c,
cell aging

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 376 SSHLKSKKGQSTSRHKKLMFK CDK7 9315650
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.81
- -

S 378 HLKSKKGQSTSRHKKLMFKTE CDK7 9315650
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.82
- -

Substrate: Cyclin dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1))

Seq-ID: P46527 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-17680   AKT1_HUMAN
MINT-17889   1433T_HUMAN
MINT-63858   GDIR1_HUMAN
MINT-1779946   MCM7_HUMAN
MINT-3379700   CDK2_HUMAN
MINT-3379718   CDK4_HUMAN
MINT-7219650   GRB2_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

cyclin-dependent protein kinase inhibitor activity,
transforming growth factor beta receptor, cytoplasmic mediator activity,
protein binding cytosol,
nucleus negative regulation of kinase activity,
regulation of cyclin-dependent protein kinase activity,
negative regulation of cell proliferation,
negative regulation of cell growth,
cell cycle arrest,
G1/S transition of mitotic cell cycle,
autophagic cell death,
cellular response to lithium ion,
induction of apoptosis,
negative regulation of gene-specific transcription

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

T 198 PKKPGLRRRQT           - 12042314
LTP

0.00
YWHAQ 14-3-3 -
0.54
- -

T 198 PKKPGLRRRQT           RSK_group 14504289
LTP

0.00
YWHAQ 14-3-3 -
0.54
- -

T 198 PKKPGLRRRQT           RSK-2 14504289
LTP

0.00
YWHAQ 14-3-3 -
0.54
- -

Substrate: RGS7 (GTPase activating protein)

Seq-ID: P49802 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-7252618   PLCG1_HUMAN
MINT-7254286   CRK_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

signal transducer activity,
protein binding heterotrimeric G-protein complex negative regulation of signal transduction,
regulation of G-protein coupled receptor protein signaling pathway,
G-protein coupled receptor protein signaling pathway

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 434 EHIYKLMKSDSYPRFIRSSAY PKC_alpha 12077120
LTP

1.00
YWHAB 14-3-3;
YWHAQ 14-3-3 RGS
0.22
2A72 52.46%

Substrate: Raf1 (RAF proto-oncogene serine/threonine-protein kinase)

Seq-ID: P04049 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-19324   KPYM_HUMAN
MINT-24923   RAP1A_HUMAN
MINT-45800   1433Z_HUMAN
MINT-51053   K1C19_HUMAN
MINT-51055   K1C18_HUMAN
MINT-51056   K2C8_HUMAN
MINT-56513   CNKR1_HUMAN
MINT-3389399   PAK1_HUMAN
MINT-3389607   PEBP1_HUMAN
MINT-3975386   1433S_HUMAN
MINT-6946517   RASH_HUMAN
MINT-7014370   MP2K1_HUMAN
MINT-7014449   AKT1_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein serine/threonine kinase activity,
metal ion binding,
receptor signaling protein activity,
ATP binding,
protein binding plasma membrane,
cytosol,
mitochondrial outer membrane protein amino acid phosphorylation,
negative regulation of cell proliferation,
apoptosis,
Ras protein signal transduction,
cell proliferation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 259 GSLSQRQRSTSTPNVHMVSTT PKA_group 11971957
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.73
- medium

S 259 GSLSQRQRSTSTPNVHMVSTT PKB_group 10576742
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.73
- medium

S 259 GSLSQRQRSTSTPNVHMVSTT - 12801936
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.73
- medium

S 259 GSLSQRQRSTSTPNVHMVSTT - 18220336
HTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.73
- medium

S 259 GSLSQRQRSTSTPNVHMVSTT - 18669648
HTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.73
- medium

S 621 HSLPKINRSASEPSLHRAAHT PKA_group 11971957
LTP

0.99
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.49
- medium

S 621 HSLPKINRSASEPSLHRAAHT - 9091312
LTP

0.99
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.49
- medium

Substrate: PKC mu (Serine/threonine kinase)

Seq-ID: Q15139 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein kinase C activity,
metal ion binding,
ATP binding,
protein binding cytosol,
integral to plasma membrane protein amino acid phosphorylation,
signal transduction,
cell proliferation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 205 NCSGVRRRRLSNVSLTGVSTI PKD1 10867018
LTP

1.00
YWHAQ 14-3-3 -
0.31
- medium

S 208 GVRRRRLSNVSLTGVSTIRTS - 15755722
LTP

1.00
YWHAQ 14-3-3 -
0.33
- medium

S 219 LTGVSTIRTSSAELSTSAPDE - 15755722
LTP

0.85
YWHAQ 14-3-3 -
0.41
- medium

S 223 STIRTSSAELSTSAPDEPLLQ - 15755722
LTP

0.75
YWHAQ 14-3-3 -
0.45
- medium

Substrate: WEE 1 tyrosine kinase (Dual specificity kinase)

Seq-ID: P30291 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-50988   1433B_HUMAN
MINT-3295375   1433Z_HUMAN
MINT-3975741   1433S_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

magnesium ion binding,
protein serine/threonine kinase activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
protein binding nucleoplasm protein amino acid phosphorylation,
cell division,
mitosis

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 642 LIGKKMNRSVSLTIY       - 15150265
LTP

0.98
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.28
- medium

S 642 LIGKKMNRSVSLTIY       - 15964826
LTP

0.98
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.28
- medium

Substrate: Pde3a (Enzyme Pphosphodiesterase)

Seq-ID: Q14432 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
MINT-3295899   1433Z_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

metal ion binding,
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity integral to membrane lipid metabolic process,
signal transduction

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 428 KLAIPKRLRRSLPPGLLRRVS - 16964243
HTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.49
- medium

S 428 KLAIPKRLRRSLPPGLLRRVS - 18669648
HTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.49
- medium

Substrate: Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR (Early response protein NAK1) (TR3 orphan receptor))

Seq-ID: P12813 [Mus musculus]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

sequence-specific DNA binding,
protein heterodimerization activity,
protein homodimerization activity,
transcription activator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
steroid hormone receptor activity nucleus transcription,
negative regulation of caspase activity,
induction of apoptosis,
positive regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 354 SLKGRRGRLPSKPKQPPDASP - 9322922
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.77
1CIT 100.82%

Substrate: YAP65 (Transcription regulatory protein)

Seq-ID: P46937 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-18935   1433T_HUMAN
MINT-68603   NHRF2_HUMAN
MINT-72743   NHRF1_HUMAN
MINT-3317930   1433Z_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

transcription corepressor activity,
transcription coactivator activity cytoplasm,
nucleus transcription,
hippo signaling cascade,
contact inhibition,
cell proliferation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 127 ALTPQHVRAHSSPASLQLGAV PKB_group 12535517
LTP

1.00
YWHAQ 14-3-3 -
0.76
- -

S 127 ALTPQHVRAHSSPASLQLGAV - 18669648
HTP

1.00
YWHAQ 14-3-3 -
0.76
- -

Substrate: Histone deacetylase 4 (Enzyme: Deacetylase)

Seq-ID: P56524 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-49703   MEF2A_HUMAN
MINT-49706   MEF2C_HUMAN
MINT-3296491   1433Z_HUMAN
MINT-3975818   1433S_HUMAN
MINT-6802058   HIF1A_HUMAN
MINT-7144512   ZN148_HUMAN
MINT-7299965   BUB1B_HUMAN
MINT-7555703   ATF2_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

potassium ion binding,
transcription repressor binding,
specific transcriptional repressor activity,
transcription activator binding,
transcription activator activity,
histone deacetylase activity,
histone deacetylase binding,
zinc ion binding histone deacetylase complex,
transcriptional repressor complex B cell differentiation,
negative regulation of gene-specific transcription from RNA polymerase II promoter,
nervous system development,
positive regulation of cell proliferation,
negative regulation of transcription factor activity,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of myotube differentiation,
transcription,
histone H4 deacetylation,
positive regulation of transcription factor activity,
response to denervation involved in regulation of muscle adaptation,
inflammatory response,
histone H3 deacetylation,
response to interleukin-1,
chromatin remodeling,
cardiac muscle hypertrophy in response to stress,
negative regulation of glycolysis,
positive regulation of protein sumoylation,
peptidyl-lysine deacetylation,
regulation of protein binding

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 246 KDDFPLRKTASEPNLKLRSRL - 10958686
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.64
- low

S 246 KDDFPLRKTASEPNLKLRSRL - 10869435
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.64
- low

S 467 RQHRPLGRTQSAPLPQNAQAL CaM-KIV 11470791
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.84
- low

S 467 RQHRPLGRTQSAPLPQNAQAL - 18669648
HTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.84
- low

S 632 GGHRPLSRAQSSPASATFPVS CaM-KIV 11470791
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.67
- low

S 632 GGHRPLSRAQSSPASATFPVS - 18669648
HTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.67
- low

Substrate: PCTAIRE1 (Serine/threonine-protein kinase PCTAIRE-1)

Seq-ID: Q00536 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

cyclin-dependent protein kinase activity,
ATP binding,
protein binding protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 119 ISTEDINKRLSLPADIRLPEG PKA_group 12154078
LTP

0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.47
- medium

S 119 ISTEDINKRLSLPADIRLPEG - 17192257
HTP

0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.47
- medium

S 153 KPLSRRLRRVSLSEIGFGKLE PKA_group 12154078
LTP

0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.23
- medium

S 153 KPLSRRLRRVSLSEIGFGKLE - 17192257
HTP

0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.23
- medium

S 153 KPLSRRLRRVSLSEIGFGKLE - 18669648
HTP

0.96
MOD_PKA_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.23
- medium

Substrate: Integrin beta 2 (Adhesion molecule)

Seq-ID: P05107 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-16748   CSN3_HUMAN
MINT-45894   SHC1_MOUSE
MINT-45897   EPS8_HUMAN
MINT-45904   RBGP1_HUMAN
MINT-45912   GULP1_HUMAN
MINT-45917   NUMB_MOUSE
MINT-45924   DAB1_MOUSE
MINT-45938   IRS1_RAT
MINT-45944   DOK1_MOUSE
MINT-45953   TLN1_MOUSE
MINT-45956   JIP1_HUMAN
MINT-50069   RANB9_HUMAN
MINT-4652127   RADI_HUMAN
MINT-4652150   CYH1_HUMAN
MINT-7226098   ABL1_HUMAN
MINT-7226365   TLN2_HUMAN
MINT-7226634   VAV_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

receptor activity,
protein kinase binding,
glycoprotein binding integrin complex apoptosis,
integrin-mediated signaling pathway,
regulation of cell shape,
inflammatory response,
cell-cell signaling,
neutrophil chemotaxis,
cell-matrix adhesion,
regulation of peptidyl-tyrosine phosphorylation,
leukocyte cell-cell adhesion

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

T 758 NNDNPLFKSATTTVMNPKFAE PKC_group 11700305
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Integrin_b_cyt
0.35
2JF1 93.15%

T 758 NNDNPLFKSATTTVMNPKFAE PKC_alpha 11700305
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Integrin_b_cyt
0.35
2JF1 93.15%

T 758 NNDNPLFKSATTTVMNPKFAE PKC_delta 11700305
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Integrin_b_cyt
0.35
2JF1 93.15%

T 758 NNDNPLFKSATTTVMNPKFAE PKC_eta 11700305
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Integrin_b_cyt
0.35
2JF1 93.15%

T 758 NNDNPLFKSATTTVMNPKFAE - 12682249
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Integrin_b_cyt
0.35
2JF1 93.15%

Substrate: BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))

Seq-ID: Q61337 [Mus musculus]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

cytosol,
mitochondrial outer membrane induction of apoptosis by extracellular signals,
glucose homeostasis,
cytokine-mediated signaling pathway,
apoptosis,
positive regulation of B cell differentiation,
positive regulation of T cell differentiation,
glucose catabolic process,
cell proliferation,
regulation of caspase activity

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 9381178
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 10949026
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 112 GAMETRSRHSSYPAGTEEDEG - 15849194
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 112 GAMETRSRHSSYPAGTEEDEG RSK_group 10880354
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 112 GAMETRSRHSSYPAGTEEDEG - 17242355
HTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 112 GAMETRSRHSSYPAGTEEDEG RSK_group 16103085
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 11983683
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.88
- medium

S 136 ELSPFRGRSRSAPPNLWAAQR PKB_group 9381178
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.66
- medium

S 136 ELSPFRGRSRSAPPNLWAAQR PKB_group 10949026
LTP

1.00
MOD_PKB_1
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.66
- medium

S 155 QRYGRELRRMSDEFEGSFKGL RSK_group 10837486
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.60
- medium

S 155 QRYGRELRRMSDEFEGSFKGL - 10837473
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.60
- medium

S 155 QRYGRELRRMSDEFEGSFKGL - 15123689
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.60
- medium

S 155 QRYGRELRRMSDEFEGSFKGL RSK_group 10880354
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 Bcl-2_BAD
0.60
- medium

Substrate: Cytokeratin 18 (Structural protein)

Seq-ID: P05783 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-51052   1433Z_HUMAN
MINT-51055   RAF1_HUMAN
MINT-61557   GRB2_HUMAN
MINT-67331   EXOC8_HUMAN
MINT-68023   HGS_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

structural molecule activity,
protein binding centriolar satellite,
keratin filament,
perinuclear region of cytoplasm negative regulation of apoptosis,
anatomical structure morphogenesis,
cell cycle,
interspecies interaction between organisms,
Golgi to plasma membrane CFTR protein transport

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 34 YGARPVSSAASVYAGAGGSGS - 9524113
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.45
- low

S 34 YGARPVSSAASVYAGAGGSGS - 16083285
HTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.45
- low

Substrate: PDK1 (3-phosphoinositide dependent protein kinase-1; serine/threonine kinase)

Seq-ID: O15530 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-13835   AKT1_HUMAN
MINT-14377   KS6B1_HUMAN
MINT-15996   1433F_HUMAN
MINT-16333   1433T_HUMAN
MINT-17466   FRAP_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

3-phosphoinositide-dependent protein kinase activity,
ATP binding,
protein binding plasma membrane,
cytosol intracellular signaling pathway,
actin cytoskeleton organization,
cellular response to insulin stimulus,
positive regulation of establishment of protein localization in plasma membrane,
negative regulation of protein kinase activity,
peptidyl-threonine phosphorylation,
activation of protein kinase B activity

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 241 SPESKQARANSFVGTAQYVSP PDK-1 10455013
LTP

1.00
YWHAH 14-3-3;
YWHAQ 14-3-3 S_TKc
0.25
1UU3 123.77%

S 241 SPESKQARANSFVGTAQYVSP - 15302935
HTP

1.00
YWHAH 14-3-3;
YWHAQ 14-3-3 S_TKc
0.25
1UU3 123.77%

S 241 SPESKQARANSFVGTAQYVSP - 18669648
HTP

1.00
YWHAH 14-3-3;
YWHAQ 14-3-3 S_TKc
0.25
1UU3 123.77%

Substrate: cdc25c (M-phase inducer phosphatase 3)

Seq-ID: P30307 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-16690   PLK1_HUMAN
MINT-3294433   1433Z_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein tyrosine phosphatase activity,
WW domain binding cytosol,
nucleoplasm regulation of cyclin-dependent protein kinase activity,
cell division,
traversing start control point of mitotic cell cycle,
protein amino acid dephosphorylation,
regulation of mitosis,
mitosis,
interspecies interaction between organisms,
DNA replication,
cell proliferation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 216 VSRSGLYRSPSMPENLNRPRL CHK2 10744722
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

S 216 VSRSGLYRSPSMPENLNRPRL - 15629715
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

S 216 VSRSGLYRSPSMPENLNRPRL CHK2 9836640
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

S 216 VSRSGLYRSPSMPENLNRPRL BRSK1 9543386
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

Substrate: Kinase suppressor of ras-1 (ATP binding)

Seq-ID: Q61097 [Mus musculus]

Download: fasta csv

Interaction Network(s): -

External Source(s):

MINT Interaction(s):
[show]

MINT-13707   1433B_HUMAN
MINT-13837   CDC37_HUMAN
MINT-14037   HS90B_HUMAN
MINT-16002   MP2K1_HUMAN
MINT-17370   HSP71_HUMAN
MINT-17529   MP2K2_HUMAN
MINT-17608   MK03_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein serine/threonine kinase activity,
metal ion binding,
ATP binding,
protein binding cytoplasm,
membrane protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 297 PSFPTLTRSKSHESQLGNRID - 9858547
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.59
- medium

S 392 LPLARLRRTESVPSDINNPVD - 9858547
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.61
- medium

S 392 LPLARLRRTESVPSDINNPVD - 12105213
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.61
- medium

Substrate: HDAC5 (histone deacetylase activity, specific transcriptional repressor activity)

Seq-ID: Q9UQL6 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-65796   EF1G_HUMAN
MINT-3318337   1433Z_HUMAN
MINT-6802102   HIF1A_HUMAN
MINT-7299978   BUB1B_HUMAN
MINT-7710106   PKN2_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein kinase C binding,
transcription repressor binding,
specific transcriptional repressor activity,
histone deacetylase activity,
transcription factor binding histone deacetylase complex,
cytoplasm B cell differentiation,
negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of myotube differentiation,
transcription,
histone deacetylation,
positive regulation of transcription factor activity,
chromatin silencing,
inflammatory response,
negative regulation of cell migration involved in sprouting angiogenesis,
chromatin remodeling,
cellular response to insulin stimulus,
regulation of protein binding

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 259 RDDFPLRKTASEPNLKVRSRL CaM-KIV 11081517
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.69
- medium

S 498 PRHRPLSRTQSSPLPQSPQAL CaM-KIV 11081517
LTP

1.00
SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 -
0.88
- medium