Phospho.ELM Currently 19650 Instances in Phospho.ELM database.

List of substrates found:

PL scramblase 1  Bcr  IKB-alpha  Myogenic factor 3  GPX1  WASF2  PKC mu  Crk  Vinexin  CD227  Ena  Rad9  Mdm2  BTK  hRAD51  APBB1  p62DOK  Caspase 9  PSTPIP1  CBL E3 ubiquitin protein ligase  Catalase  Caveolin-1  Crk-like protein  DNA repair protein RAD52 homolog  Abl  Phospholipid scramblase 4  p73  JAK2  TOP1  Lipocortin I (annexinI)  CDK5 

Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Erythrocytes phospholipid scramblase
Homo sapiens
Y69
AGFPVPNQPVYNQPVYNQPVG
Abl;
Src
11390389
12871937
LTP
SHC PTB
-
-
-
     
Y74
PNQPVYNQPVYNQPVGAAGVP
Abl;
Src
11390389
12871937
LTP
SHC PTB
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Breakpoint cluster region protein
Homo sapiens
Y177
QPGADAEKPFYVNVEFHHERG
Fes;
Abl;
HCK
8955135
10405761
12522270
9178913
12124177
9407116
HTP/LTP
GRB2 SH2
-
-
-
     
Y360
SSRVSPSPTTYRMFRDKSRSP
Abl
9467953
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Major histocompatibility complex enhancer-binding protein MAD3
Homo sapiens
Y305
FTEFTEDELPYDDCVFGGQRL
Abl
14757045
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Transcription factor
Mus musculus
-
Y30
LCSFETADDFYDDPCFDSPDL
Abl
12415271
LTP
-
-
-
-
     
Y212
RSNCSDGMMDYSGPPSGPRRQ
Abl
12415271
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cellular glutathione peroxidase
Homo sapiens
-
Y96
KNEEILNSLKYVRPGGGFEPN
Abl;
Abl2
12893824
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Homo sapiens
Y150
RDDGKEALKFYTDPSYFFDLW
Abl
15657136
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Serine/threonine kinase
Homo sapiens
Y432
TVMKEGWMVHYTSKDTLRKRH
Abl
12637538
LTP
-
PH
-
-
     
Y463
LFQNDTGSRYYKEIPLSEILS
Abl
12637538
12505989
LTP
-
PH
-
-
     
Y502
FEITTANVVYYVGENVVNPSS
Abl
12637538
LTP
-
PH
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
The Crk protein contains a single SH2 and two SH3 domains in the order SH2-SH3-SH3
Mus musculus
Y221
QPLGGPEPGPYAQPSVNTPLP
Abl;
IGF1R;
Abl2
8194526
9480911
LTP
-
-
-
-
             
The Crk protein contains a single SH2 and two SH3 domains in the order SH2-SH3-SH3
Homo sapiens
Y221
QPLGGPEPGPYAQPSVNTPLP
Abl;
EGFR;
IGF1R
12198159
9642287
9480991
8194526
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
unclassified
Rattus norvegicus
Y127
DGSQHPDPAWYQTWPGPGSQP
Abl
16831423
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
CD antigen
Homo sapiens
Y1243
SAGNGGSSLSYTNPAVAAASA
Abl
7664271
14521915
16888623
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Abl substrate with SH3 binding properties
Drosophila melanogaster
Y274
PGGPPTNGNGYEEDMGYRTMT
Abl
9418863
LTP
-
-
-
-
     
Y456
PQPPLQNGGMYMVGHGHLPSS
Abl
9418863
LTP
-
-
-
-
     
Y474
PSSASANSVVYASQQQMLPQA
Abl
9418863
LTP
-
-
-
-
     
Y499
PQAPTMPGPGYGGPPVPPPQQ
Abl
9418863
LTP
-
-
-
-
     
Y515
PPPQQQAENPYGQVPMPPPMN
Abl
9418863
LTP
-
-
-
-
     
Y675
SSTSSGGSGNYGTIGRSSNGM
Abl
9418863
LTP
-
-
-
1v0e
1v0f
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cell cycle checkpoint control protein (RAD9)
Homo sapiens
Y28
HSLSRIGDELYLEPLEDGLSL
Abl
11971963
LTP
-
Rad9
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2. -) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2)
Homo sapiens
Y394
QASQSQESEDYSQPSTSSSII
Abl
14757045
12110584
16702947
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Bruton's tyrosine kinase
Homo sapiens
Y223
TSELKKVVALYDYMPMNANDL
Abl;
BTK
8630736
12445832
12573241
LTP
-
SH3
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
DNA repair protein RAD51 homolog 1
Homo sapiens
Y54
AGFHTVEAVAYAPKKELINIK
Abl
9461559
LTP
-
-
-
-
     
Y315
GRGETRICKIYDSPCLPEAEA
Abl
11684015
10212258
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
beta-amyloid binding, histone acetyltransferase binding
Mus musculus
-
Y547
NELVQKFQVYYLGNVPVAKPV
Abl
15031292
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Docking protein, common target of PTKs
Mus musculus
Y361
KLTDSKEDPIYDEPEGLAPAP
Abl
15592455
15148308
HTP/LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cysteine protease
Homo sapiens
Y153
ESLRGNADLAYILSMEPCGHC
Abl
15657060
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adapter molecule
Homo sapiens
Y345
TPTPERNEGVYTAIAVQEIQG
Abl
11163214
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adaptor molecule
Homo sapiens
Y700
EQCEGEEDTEYMTPSSRPLRP
Fyn;
Lck;
Abl;
Syk;
Yes;
InsR
9525940
9102067
12522270
11997497
10829062
HTP/LTP
CRK SH2;
VAV_group SH2
-
-
-
     
Y774
PEESENEDDGYDVPKPPVPAV
Fyn;
Lck;
Abl;
Syk;
Src;
InsR
9525940
12522270
12604776
10829062
HTP/LTP
CRKL SH2
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Occurs in almost all aerobically respiring organisms
Homo sapiens
Y231
KLVNANGEAVYCKFHYKTDQG
Abl;
Abl2
12777400
LTP
-
Catalase
-
-
     
Y386
NCPYRARVANYQRDGPMCMQD
Abl;
Abl2
12777400
LTP
-
Catalase
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
May act as a scaffolding protein within the caveolar membranes
Mus musculus
Y14
GKYVDSEGHLYTVPIREQGNI
Abl;
Src
12036959
11075810
8632005
12531427
11094059
15592455
HTP/LTP
GRB7 SH2
Caveolin
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Crk-like protein
Homo sapiens
Y207
SYGIPEPAHAYAQPQTTTPLP
Abl
9710592
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Involved in double-stranded break repair
Homo sapiens
Y104
DFVDLNNGKFYVGVCAFVRVQ
Abl
14757045
LTP
-
Rad52_Rad22
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Proto-oncogene tyrosine-protein kinase ABL1
Mus musculus
Y393
GLSRLMTGDTYTAHAGAKFPI
Abl
1956339
LTP
-
-
-
1opl
1opk
2fo0
1fpu
1iep
             
Proto-oncogene tyrosine-protein kinase ABL1
Homo sapiens
Y393
GLSRLMTGDTYTAHAGAKFPI
Abl;
Src
11781820
10964922
12522270
HTP/LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Transport/cargo protein
Homo sapiens
-
Y83
QPVGGIHPVRYQPGKYPMPNQ
Abl
14757045
LTP
-
-
-
-
     
Y88
IHPVRYQPGKYPMPNQSVPIT
Abl
14757045
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Member of the TP53 family. It participates in the apoptotic response to DNA damage
Homo sapiens
Y99
HAASVPTHSPYAQPSSTFDTM
Abl
10391251
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cytoplasmic tyrosine kinase
Mus musculus
Y1007
LTKVLPQDKEYYKVKEPGESP
Abl;
JAK2
9111318
11593427
15143187
16705160
16705159
15923602
15793561
LTP
-
-
-
-
     
Y1008
TKVLPQDKEYYKVKEPGESPI
Abl;
JAK3
9111318
11593427
16705160
16705159
15923602
15793561
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
DNA topoisomerase type I activity
Homo sapiens
Y268
TFFAKMLDHEYTTKEIFRKNF
Abl
15448168
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Ca++, phospholipids and actin-binding protein
Homo sapiens
Y21
AWFIENEEQEYVQTVKSSKGG
Abl;
Src;
EGFR
2457390
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cell division protein kinase 5
Homo sapiens
Y15
EKLEKIGEGTYGTVFKAKNRE
Abl
14757045
9038181
LTP
-
S_TKc
-
-