Phospho.ELM Currently 19650 Instances in Phospho.ELM database.

List of substrates found:

CD79B  Microtubule associated protein 2  CD79A  CD32  Hic-5  PLD2  CD3 zeta  c-kit  LAMP  CBL E3 ubiquitin protein ligase  Shc  PLC gamma 2  SCAP1  Caveolin-1  FYN  Inositol 1,4,5-trisphosphate receptor type 1  Grb10  NMT1  ITCH  FYN-binding protein  Beta-catenin  Postsynaptic density protein PSD-93  Glutamate [NMDA] receptor subunit epsilon 2  CD150 

Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
B cell antigen receptor
Homo sapiens
Y196
SKAGMEEDHTYEGLDIDQTAT
Fyn;
Lyn
9531288
LTP
-
-
-
     
Y207
EGLDIDQTATYEDIVTLRTGE
Fyn;
Lyn
9531288
LTP
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cytoskeletal protein
Homo sapiens
Y67
AFGEHGSQGTYSNTKENGING
Fyn;
Lyn
15536091
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
B cell antigen receptor
Homo sapiens
Y199
EGLNLDDCSMYEDISRGLQGT
Fyn
9531288
LTP
-
ITAM
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
CD antigen. Binds to the Fc region of immunoglobulins gamma.
Homo sapiens
Y281
KRQLEETNNDYETADGGYMTL
Fyn;
Lyn;
Syk;
BLK
8756631
LTP
-
-
-
-
     
Y288
NNDYETADGGYMTLNPRAPTD
Fyn;
Lyn;
Syk;
BLK
8756631
LTP
-
-
-
     
Y304
RAPTDDDKNIYLTLPPNDHVN
Fyn;
Lyn;
Syk;
BLK
8756631
LTP
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Androgen receptor binding
Homo sapiens
Y60
SGASGDKDHLYSTVCKPRSPK
Fyn
10838081
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Phospholipase D2
Mus musculus
Y11
MTVTQKNLFPYGDYLNSSQLH
Fyn;
Fgr
9837959
15282299
LTP
-
-
-
-
     
Y14
TQKNLFPYGDYLNSSQLHMEP
Fyn;
Fgr
15282299
LTP
-
-
-
-
     
Y165
SARHTASKQKYLENYLNRLLT
Fyn;
Fgr
15282299
LTP
-
-
-
-
     
Y470
LAFGRWDDVQYRLTDLGDPSE
Fyn;
Fgr
15282299
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
T-cell surface glycoprotein CD3 zeta chain precursor (from PhosphoBase)
Homo sapiens
Y111
QRRKNPQEGLYNELQKDKMAE
Fyn
8578591
12522270
15144186
15592455
16094384
15659558
HTP/LTP
-
-
-
     
Y123
ELQKDKMAEAYSEIGMKGERR
Fyn
8578591
12522270
16094384
15659558
HTP/LTP
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Receptor tyrosine kinase
Mus musculus
-
Y934
KQISDSTKHIYSNLANCNPNP
Fyn
N.N.
12374739
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Unclassified
Human herpesvirus 8
-
Y480
QAATQPTDDLYEEVLFPRN
Fyn;
Lck;
Yes;
HCK
12915550
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adaptor molecule
Homo sapiens
Y700
EQCEGEEDTEYMTPSSRPLRP
Fyn;
Lck;
Abl;
Syk;
Yes;
InsR
9525940
9102067
12522270
11997497
10829062
HTP/LTP
CRK SH2;
VAV_group SH2
-
-
-
     
Y731
DCDQQIDSCTYEAMYNIQSQA
Fyn;
Lck;
Syk;
Src;
Yes;
HCK
9525940
10934191
9890970
12604776
LTP
PIK3R1 SH2
-
-
-
     
Y774
PEESENEDDGYDVPKPPVPAV
Fyn;
Lck;
Abl;
Syk;
Src;
InsR
9525940
12522270
12604776
10829062
HTP/LTP
CRKL SH2
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adaptor molecule
Homo sapiens
Y427
PGRELFDDPSYVNVQNLDKAR
Fyn;
Lck;
InsR;
PDGFR_group;
FLT4
11075717
9710204
8610109
9741627
12522270
15592455
9927207
HTP/LTP
GRB2 SH2
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Involved in transmembrane signaling
Homo sapiens
Y743
YPVTPELLERYNMERDINSLY
Fyn;
Lck;
Lyn
12181444
LTP
-
-
-
-
     
Y753
YNMERDINSLYDVSRMYVDPS
Fyn;
Lck;
Lyn;
Src;
BTK
11507089
11606584
12181444
15144186
HTP/LTP
-
-
-
-
     
Y759
INSLYDVSRMYVDPSEINPSM
Fyn;
Lck;
Lyn;
Src;
BTK
11507089
11606584
12181444
14656219
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
protein binding, protein-tyrosine kinase activity
Homo sapiens
Y219
LKDLSSLTIPYEEDEEEEEKE
Fyn
11909961
LTP
-
-
-
-
     
Y232
DEEEEEKEETYDDIDGFDSPS
Fyn
11909961
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
May act as a scaffolding protein within the caveolar membranes
Homo sapiens
Y14
GKYVDSEGHLYTVPIREQGNI
Fyn;
Src
12921535
14992595
LTP
-
Caveolin
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Cytoplasmic tyrosine kinase
Homo sapiens
Y28
RDGSLNQSSGYRYGTDPTPQH
Fyn;
PDGFR beta
9425276
LTP
-
-
-
-
     
Y30
GSLNQSSGYRYGTDPTPQHYP
Fyn
9425276
LTP
-
-
-
-
     
Y39
RYGTDPTPQHYPSFGVTSIPN
Fyn
9425276
LTP
-
-
-
-
     
Y420
GLARLIEDNEYTARQGAKFPI
Fyn
1985196
17192257
18088087
HTP/LTP
-
TyrKc
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
inositol 1,4,5-trisphosphate-binding protein type 1 receptor (from PhosphoBase)
Homo sapiens
Y353
RLRNAQEKMVYSLVSVPEGND
Fyn
14761954
LTP
-
MIR
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adapter molecule
Homo sapiens
Y67
NDMNASLESLYSACSMQSDTV
Fyn;
Src
10871840
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Unclassified
Homo sapiens
Y180
KELYTLLNENYVEDDDNMFRF
Fyn;
Lyn
11594778
LTP
-
NMT
-
1rxt
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
protein binding, ubiquitin-protein ligase activity
Homo sapiens
Y420
AMQQFNQRFIYGNQDLFATSQ
Fyn
16387660
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adaptor molecule
Homo sapiens
Y595
SRPIEDDQEVYDDVAEQDDIS
Fyn
10570256
10409671
LTP
LCP2 SH2
-
-
-
     
Y651
PKQLDMGDEVYDDVDTSDFPV
Fyn
10570256
10409671
LTP
LCP2 SH2
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Adhesion molecule
Homo sapiens
Y142
LKHAVVNLINYQDDAELATRA
Fyn
12640114
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Required for perception of chronic pain through NMDA receptor signaling
Rattus norvegicus
-
Y348
DDYTRPPEPVYSTVNKLCDKP
Fyn
13129934
LTP
-
-
-
-
             
Required for perception of chronic pain through NMDA receptor signaling
Mus musculus
-
Y348
DDYTRPPEPVYSTVNKLCDKP
Fyn
13129934
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
Extracellular ligand gated channel
Mus musculus
-
Y932
LDFIRRESSVYDISEHRRSFT
Fyn
11024032
LTP
-
-
-
-
     
Y1039
SSKHSQLSDLYGKFSFKSDRY
Fyn
11024032
LTP
-
-
-
-
     
Y1070
VSDISTHTVTYGNIEGNAAKR
Fyn
11024032
LTP
-
-
-
-
     
Y1109
RREFDEIELAYRRRPPRSPDH
Fyn
11024032
LTP
-
-
-
-
     
Y1252
CEACKKAGNLYDISEDNSLQE
Fyn
11024032
LTP
-
-
-
-
     
Y1336
DKGRFMDGSPYAHMFEMPAGE
Fyn
11024032
LTP
-
-
-
-
     
Y1472
AFNGSSNGHVYEKLSSIESDV
Fyn
12451687
11024032
LTP
-
-
-
-
             
 
Substrate
Short Description
UniPROT/Ensembl Id
Species
Interaction Network
Position
Sequence
Kinase
PubMed
Source
Phospho-peptide
Binding Domain
Smart/Pfam
ELM
PDB/MSD
T cell antigen receptor
Homo sapiens
Y281
TTVEKKSLTIYAQVQKPGPLQ
Fyn
11806999
LTP
-
-
-
-
     
Y307
FPAQDPCTTIYVAATEPVPES
Fyn;
Lck
11806999
LTP
-
-
-
-
     
Y327
SVQETNSITVYASVTLPES
Fyn;
Lyn
11806999
15315965
LTP
-
-
-
-