Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

Substrate:

Abl (Proto-oncogene tyrosine-protein kinase ABL1)

Seq-ID:

P00520 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-49663   APBB1_RAT
MINT-49984   A4_HUMAN
MINT-59456   RIN1_HUMAN
MINT-60758   DOK2_MOUSE
MINT-73478   ABI1_MOUSE
MINT-73480   PPIP1_MOUSE
MINT-7235318   CRK_HUMAN
MINT-7235335   NCK1_HUMAN
MINT-7235351   SRBS1_HUMAN
MINT-7235383   CRKL_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
magnesium ion binding, manganese ion binding, protein domain specific binding, non-membrane spanning protein tyrosine kinase activity, ATP binding	cytosol, cytoskeleton, nucleus	regulation of cell cycle, actin cytoskeleton organization, signal transduction, cell adhesion, peptidyl-tyrosine phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	547	RAAEQKDAPDTPELLHTKGLG	CDK_group	1956339	LTP	0.00		-	-	0.82	-	-
S	569	SDALDSEPAVSPLLPRKERGP	CDK_group	1956339	LTP	0.63		-	-	0.86	-	-

Substrate:

Amphiphysin (Amphiphysin)

Seq-ID:

P49418 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16056   SYNJ1_HUMAN
MINT-50453   AP2A2_MOUSE
MINT-65945   DYN1_HUMAN
MINT-2516534   DYN2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cell junction, synaptic vesicle membrane, actin cytoskeleton	synaptic transmission

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	272	SPPEEPSPLPSPTASPNHTLA	CDK_group	11113134	LTP	1.00	-	-	0.93	-	medium
S	276	EPSPLPSPTASPNHTLAPASP	CDK_group	11113134	LTP	1.00	-	-	0.89	-	medium
S	285	ASPNHTLAPASPAPARPRSPS	CDK_group	11113134	LTP	1.00	-	-	0.90	-	medium

Substrate:

Caldesmon (Actin and myosin binding protein)

Seq-ID:

P12957 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
myosin binding, actin binding, calmodulin binding	myofibril	muscle contraction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	597	SEEKKPFKCFSPKGSSLKIEE	CDK_group	1939059	LTP	1.00		-	Caldesmon	0.53	-	low
S	682	SMWEKGNVFSSPGGTGTPNKE	CDK_group	1939059	LTP	1.00		-	Caldesmon	0.76	-	low
T	688	NVFSSPGGTGTPNKETAGLKV	CDK_group	1939059	LTP	1.00	MOD_CDK_SPxK_1	-	Caldesmon	0.75	-	low
T	711	SSRINEWLTKTPEGNKSPAPK	CDK_group	1939059	LTP	1.00		-	Caldesmon	0.79	-	low
S	717	WLTKTPEGNKSPAPKPSDLRP	CDK_group	1939059	LTP	1.00		-	Caldesmon	0.87	-	low

Substrate:

Caldesmon (Actin and myosin binding protein)

Seq-ID:

Q62736 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
myosin binding, actin binding, calmodulin binding	myofibril, neuronal cell body, dendritic spine, actin filament, postsynaptic density	positive regulation of protein binding, muscle contraction, actin filament bundle assembly, female pregnancy

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	249	HKLKQTENAFSPSRSGGRASG	CDK_group	1986309	LTP	1.00	MOD_CDK_SPxK_1	-	Caldesmon	0.83	-	medium
S	462	SMWEKGSVFSSPSASGTPNKE	CDK_group	1986309	LTP	0.94		-	Caldesmon	0.68	-	medium
T	468	SVFSSPSASGTPNKETAGLKV	CDK_group	1986309	LTP	1.00	MOD_CDK_SPxK_1	-	Caldesmon	0.68	-	medium
S	491	SSRINEWLTKSPDGNKSPAPK	CDK_group	1986309	LTP	0.09		-	Caldesmon	0.76	-	medium
S	497	WLTKSPDGNKSPAPKPSDLRP	CDK_group	1986309	LTP	1.00		-	Caldesmon	0.86	-	medium
S	527	WEKQSVDKVTSPTKV	CDK_group	1986309	LTP	1.00	MOD_CDK_SPxK_1	-	Caldesmon	0.69	-	medium

Substrate:

Casein kinase II, alpha chain (casein kinase II, alpha chain (CKII) (EC 2.7.1.37) (from PhosphoBase))

Seq-ID:

P68400 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14550   ENPL_HUMAN
MINT-15215   UB2R1_HUMAN
MINT-15821   PIN1_HUMAN
MINT-17591   TCP4_HUMAN
MINT-50090   TF65_HUMAN
MINT-50947   1433B_HUMAN
MINT-51176   XRCC4_HUMAN
MINT-51183   XRCC1_HUMAN
MINT-62785   CSK2B_HUMAN
MINT-63998   ZHX1_HUMAN
MINT-1779097   KAP2_BOVIN
MINT-3372672   PACS1_HUMAN
MINT-3975397   1433S_HUMAN
MINT-4791613   HIF1A_HUMAN
MINT-4961111   KANK2_HUMAN
MINT-6628644   LT_SV40
MINT-6628799   VE7_HPV16
MINT-6744190   PTN1_HUMAN
MINT-6805408   MDC1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein N-terminus binding	plasma membrane, Sin3 complex, NuRD complex	protein amino acid phosphorylation, signal transduction, Wnt receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	344	MGSSSMPGGSTPVSSANMMSG	CDK_group	7592773	LTP	0.62	-	-	0.64	-	-
T	344	MGSSSMPGGSTPVSSANMMSG	CDK_group	7592773	LTP	0.62	-	-	0.64	-	-
T	360	NMMSGISSVPTPSPLGPLAGS	CDK_group	7592773	LTP	-	-	-	0.56	-	-
T	360	NMMSGISSVPTPSPLGPLAGS	CDK_group	7592773	LTP	-	-	-	0.56	-	-
S	362	MSGISSVPTPSPLGPLAGSPV	CDK_group	7592773	LTP	-	-	-	0.54	-	-
S	362	MSGISSVPTPSPLGPLAGSPV	CDK_group	7592773	LTP	-	-	-	0.54	-	-
S	370	TPSPLGPLAGSPVIAAANPLG	CDK_group	7592773	LTP	0.60	-	-	0.54	-	-
S	370	TPSPLGPLAGSPVIAAANPLG	CDK_group	7592773	LTP	0.60	-	-	0.54	-	-

Substrate:

Casein kinase, II beta (Casein kinase II beta chain)

Seq-ID:

P67870 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51394   CHK1_HUMAN
MINT-62783   CSK22_HUMAN
MINT-62784   LYN_HUMAN
MINT-62785   CSK21_HUMAN
MINT-62787   RL5_HUMAN
MINT-62789   MBD4_HUMAN
MINT-2857838   COIL_HUMAN
MINT-3372614   PACS1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase regulator activity, identical protein binding, protein domain specific binding, transcription factor binding, receptor binding	protein kinase CK2 complex, cytoplasm	negative regulation of cell proliferation, Wnt receptor signaling pathway, adiponectin-mediated signaling pathway, cellular protein complex assembly, regulation of DNA binding

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	209	LQLQAASNFKSPVKTIR	CDK_group	7578274	LTP	0.30	MOD_CDK_SPxK_1	-	-	0.33	-	-
S	209	LQLQAASNFKSPVKTIR	CDK_group	1939094	LTP	0.30	MOD_CDK_SPxK_1	-	-	0.33	-	-
S	209	LQLQAASNFKSPVKTIR	CDK_group	12551973	LTP	0.30	MOD_CDK_SPxK_1	-	-	0.33	-	-

Substrate:

CROC4 (CROC-4 transcriptional activator)

Seq-ID:

ENSP00000357225 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

Molecular Function	Cellular Component	Biological Process
	nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	91	STTDSSRAPSSPRPPGSTSHC	CDK_group	10995546	LTP	-		-	-	0.86	-	low

Substrate:

DARPP-32 (Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32))

Seq-ID:

Q9UD71 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity, protein kinase inhibitor activity	cytosol	signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	75	KSKRPNPCAYTPPSLKAVQRI	CDK_group	10604473	LTP	0.73		-	DARPP-32	0.74	-	low

Substrate:

Desmin (desmin (from PhosphoBase))

Seq-ID:

P02542 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity	intermediate filament, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	SQSYSSSQRVSSYRRT	CDK_group	8439342	LTP	0.22		-	-	0.47	-	low
S	22	SYRRTFGGGTSPVFPRASFGS	CDK_group	8439342	LTP	0.51		-	Filament_head	0.43	-	low
T	64	TLSTFRTTRVTPLRTYGSAYQ	CDK_group	8439342	LTP	0.17	MOD_CDK_SPxK_1	-	Filament_head	0.44	-	low

Substrate:

Disabled homolog 1 (Adapter molecule functioning in neural development)

Seq-ID:

O75553 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-74508 ERBB2_HUMAN
MINT-74509 ERBB3_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	524	SPPTPAPRQSSPSKSSASHAS	CDK_group	12077184	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.96	-	low
S	548	TDDIFEEGFESPSKSEEQEAP	CDK_group	12077184	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.94	-	low

Substrate:

Dynamin 1 (Dynamin-1)

Seq-ID:

Q05193 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-65945   AMPH_HUMAN
MINT-65948   ITSN1_HUMAN
MINT-65949   SH3G2_HUMAN
MINT-65952   GRB2_HUMAN
MINT-65953   SRC_HUMAN
MINT-7102122   MYO1E_HUMAN
MINT-7244638   ABL1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, motor activity, protein binding	microtubule	receptor-mediated endocytosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	774	QVQSVPAGRRSPTSSPTPQRR	CDK_group	12855954	LTP	0.59		-	-	0.92	-	medium
S	778	VPAGRRSPTSSPTPQRRAPAV	CDK_group	12855954	LTP	0.35	MOD_CDK_SPxK_1	-	-	0.95	-	medium

Substrate:

Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )

Seq-ID:

P03372 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13786   BRCA1_HUMAN
MINT-50646   STA5A_HUMAN
MINT-50709   M3K1_HUMAN
MINT-5222241   NCOA1_HUMAN
MINT-6169667   EGFR_HUMAN
MINT-6614126   SMCA4_HUMAN
MINT-6614301   CHD3_HUMAN
MINT-6614361   MTA1_HUMAN
MINT-6614421   MTA2_HUMAN
MINT-6761899   PTN1_HUMAN
MINT-6761906   PTN6_HUMAN
MINT-7013584   PA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
beta-catenin binding, nitric-oxide synthase regulator activity, estrogen response element binding, steroid binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, estrogen receptor activity	chromatin remodeling complex	response to estradiol stimulus, transcription, DNA-dependent, regulation of transcription, DNA-dependent, positive regulation of retinoic acid receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	104	LGGFPPLNSVSPSPLMLLHPP	CDK_group	10949034	LTP	0.61	MOD_GSK3_1	-	Oest_recep	0.48	-	-
S	104	LGGFPPLNSVSPSPLMLLHPP	CDK_group	10428798	LTP	0.61	MOD_GSK3_1	-	Oest_recep	0.48	-	-
S	106	GFPPLNSVSPSPLMLLHPPPQ	CDK_group	10428798	LTP	0.96	MOD_GSK3_1	-	Oest_recep	0.52	-	-

Substrate:

Glutamate [NMDA] receptor subunit epsilon 1 (glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D-aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A))

Seq-ID:

Q12879 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-1900829 DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
N-methyl-D-aspartate selective glutamate receptor activity, zinc ion binding	N-methyl-D-aspartate selective glutamate receptor complex, cell junction, outer membrane-bounded periplasmic space, postsynaptic membrane	response to ethanol

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1232	PTYSGHFTMRSPFKCDACLRM	CDK_group	11675505	LTP	0.34	MOD_CDK_SPxK_1	-	NMDAR2_C	0.31	-	low

Substrate:

HCDH1 (Cell cycle control protein)

Seq-ID:

Q9UM11 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-65766 DNJA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
enzyme activator activity, protein binding	cytosol, anaphase-promoting complex, nucleoplasm	cell division, DNA repair, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, G2/M transition DNA damage checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, mitosis, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	151	DGNDVSPYSLSPVSNKSQKLL	CDK_group	12560341	LTP	1.00		-	-	0.55	-	high
S	163	VSNKSQKLLRSPRKPTRKISK	CDK_group	12560341	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.54	-	high

Substrate:

Ik3-1 (Cyclin-dependent kinase binding protein.)

Seq-ID:

Q9ESJ1 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cyclin-dependent protein kinase regulator activity, protein binding	nucleus, growth cone	nervous system development, regulation of cell division, regulation of cell cycle, cell division, G1/S transition of mitotic cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	274	PLRRCRTLSGSPRPKNFKKIH	CDK_group	11733001	LTP	1.00		-	-	0.52	-	low

Substrate:

Kinesin-like protein KIF11 (sin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor interacting protein 5) (TRIP5) (Kinesin-like protein 1))

Seq-ID:

P52732 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-48095 IKKE_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding, microtubule motor activity, ATP binding	spindle, chromatin remodeling complex, microtubule, kinesin complex	cell division, microtubule-based movement, spindle assembly involved in mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	926	DLKLDIPTGTTPQRKSYLYPS	CDK_group	9235942	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.48	-	medium
T	926	DLKLDIPTGTTPQRKSYLYPS	CDK_group	8548803	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.48	-	medium

Substrate:

Lamin A/C (lamin A (70 kD lamin) (from PhosphoBase))

Seq-ID:

P02545 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51248 SMAD3_HUMAN
MINT-3297814 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, protein binding	lamin filament, nuclear envelope, perinuclear region of cytoplasm	muscle organ development, positive regulation of cell aging

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	19	ATRSGAQASSTPLSPTRITRL	CDK_group	7915280	LTP	0.98	MOD_CDK_SPxK_1	-	-	0.72	-	-
S	22	SGAQASSTPLSPTRITRLQEK	CDK_group	7915280	LTP	0.97	MOD_CDK_SPxK_1	-	-	0.71	-	-

Substrate:

Lamin A/C (lamin A (70 kD lamin) (from PhosphoBase))

Seq-ID:

P48678 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, protein binding	lamin filament, nuclear envelope	nuclear envelope organization, sterol regulatory element binding protein nuclear translocation, ventricular cardiac muscle cell development, positive regulation of cell aging

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	390	LEGEEERLRLSPSPTSQRSRG	CDK_group	1959608	LTP	1.00		-	-	0.78	-	-
S	392	GEEERLRLSPSPTSQRSRGRA	CDK_group	8477740	LTP	1.00		-	-	0.81	-	-

Substrate:

Lamin B receptor (lamin B receptor (from PhosphoBase))

Seq-ID:

P23913 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, DNA binding	nuclear inner membrane, integral to membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	71	KQRKSQSSSSSPSRRSRSRSR	CDK_group	9045635	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.89	-	medium

Substrate:

Lamin B1 (lamin B1 (from PhosphoBase))

Seq-ID:

P20700 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3297843 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, protein binding	nuclear inner membrane, lamin filament

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	23	SRAGGPTTPLSPTRLSRLQEK	CDK_group	2188730	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.80	-	low
S	393	GEEERLKLSPSPSSRVTVSRA	CDK_group	2188730	LTP	0.98		-	-	0.63	-	low

Substrate:

Lamin Dm0 (lamin Dm0 (from PhosphoBase))

Seq-ID:

P08928 [Drosophila melanogaster]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-42096 IMA_DROME
MINT-42822 OTE_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, receptor binding	lipid particle, microtubule associated complex, lamin filament, nuclear envelope	gonad morphogenesis, terminal branching, open tracheal system, central nervous system development, compound eye morphogenesis, nuclear migration, chromatin silencing, chitin-based cuticle development, mitotic nuclear envelope reassembly, digestive tract morphogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	42	PPSTHSQTASSPLSPTRHSRV	CDK_group	9013881	LTP	0.45	MOD_CDK_SPxK_1	-	-	0.93	-	medium

Substrate:

MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1))

Seq-ID:

Q02750 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16002   KSR1_MOUSE
MINT-3391583   M3K1_HUMAN
MINT-4300484   MK01_HUMAN
MINT-7014370   RAF1_HUMAN
MINT-7014390   MK03_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, MAP kinase kinase activity, ATP binding, protein tyrosine kinase activity	cytosol	senescence, negative regulation of cell proliferation, cell cycle arrest, chemotaxis, Ras protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	286	GCQVEGDAAETPPRPRTPGRP	CDK_group	11684694	LTP	0.12	MOD_CDK_SPxK_1	-	S_TKc	0.74	-	-

Substrate:

Myogenic factor 3 (Transcription factor)

Seq-ID:

P15172 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15523 SRF_HUMAN
MINT-61952 SMAD4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
RNA polymerase II transcription factor activity, enhancer binding, transcription coactivator activity		protein amino acid phosphorylation, transcription, skeletal muscle tissue development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	200	EHYSGDSDASSPRSNCSDGMM	CDK_group	9710583	LTP	1.00		-	-	0.76	-	-

Substrate:

Nestin (Nestin)

Seq-ID:

P48681 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity	intermediate filament	central nervous system development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	315	LLEAENSRLQTPGGGSKTSLS	CDK_group	12832492	LTP	1.00		-	-	0.70	-	medium
T	1299	DELGETLPDSTPLGFYLRSPT	CDK_group	12832492	LTP	1.00		-	-	0.86	-	medium

Substrate:

p53 (Cellular tumor antigen p53)

Seq-ID:

P04637 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13742   CHK2_HUMAN
MINT-15878   UBP7_HUMAN
MINT-16161   BRCA1_HUMAN
MINT-16977   PARP1_HUMAN
MINT-19990   PIN1_HUMAN
MINT-24859   ASPP2_HUMAN
MINT-45889   CEBPZ_HUMAN
MINT-49767   ATM_HUMAN
MINT-50577   SAE1_HUMAN
MINT-56524   SP1_HUMAN
MINT-58470   MED1_HUMAN
MINT-58672   HNRL1_HUMAN
MINT-60094   HIPK2_HUMAN
MINT-61312   MK08_HUMAN
MINT-61317   WWOX_HUMAN
MINT-62206   PP1A_HUMAN
MINT-63290   ARI2_HUMAN
MINT-63365   KITH_HUMAN
MINT-63497   ZNF24_HUMAN
MINT-63537   IF2B_HUMAN
MINT-63547   RAB4A_HUMAN
MINT-63559   SAT1_HUMAN
MINT-64119   STX5_HUMAN
MINT-64188   MD2BP_HUMAN
MINT-64748   K0087_HUMAN
MINT-65132   HSPB1_HUMAN
MINT-65272   MPH6_HUMAN
MINT-68565   BMX_HUMAN
MINT-74886   NPM_HUMAN
MINT-74925   1433Z_HUMAN
MINT-1795431   NMT1_HUMAN
MINT-1891378   CDN1A_HUMAN
MINT-1958329   CHK1_HUMAN
MINT-2634790   RGRF1_HUMAN
MINT-2858243   DVL2_HUMAN
MINT-2866927   SCAM1_HUMAN
MINT-3390028   KC1D_RAT
MINT-3979604   P53_MOUSE
MINT-4049689   NR4A1_HUMAN
MINT-4052116   SYVN1_HUMAN
MINT-4052873   GRP78_HUMAN
MINT-4302642   HS71L_HUMAN
MINT-4303978   XPO1_HUMAN
MINT-4329805   TOPRS_HUMAN
MINT-4793180   EGR1_HUMAN
MINT-4793253   GSK3B_HUMAN
MINT-4793489   PML_HUMAN
MINT-5114724   ZN363_HUMAN
MINT-5207405   HDAC8_HUMAN
MINT-6540866   PSME3_HUMAN
MINT-6540889   MDM2_HUMAN
MINT-6628692   LT_SV40
MINT-6665320   CBP_HUMAN
MINT-6701342   MAP1B_HUMAN
MINT-7013631   PA1_HUMAN
MINT-7013916   RYBP_HUMAN
MINT-7103733   ANDR_HUMAN
MINT-7144912   TOE1_HUMAN
MINT-7222784   FRAP_HUMAN
MINT-7263630   EP300_HUMAN
MINT-7266250   PLK1_HUMAN
MINT-7294020   FAK1_HUMAN
MINT-7295816   IKKB_HUMAN
MINT-7557644   GRP75_HUMAN
MINT-7711943   1433S_HUMAN
MINT-7717378   PHB_HUMAN
MINT-7718917   SNAI1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription activator activity, protease binding, DNA strand annealing activity, chromatin binding, copper ion binding, ATP binding, transcription factor binding, chaperone binding, zinc ion binding, histone acetyltransferase binding, promoter binding, sequence-specific DNA binding transcription factor activity, protein N-terminus binding, protein heterodimerization activity, protein phosphatase 2A binding, protein kinase binding, ubiquitin protein ligase binding	nucleolus, nuclear matrix, insoluble fraction, protein complex, endoplasmic reticulum, PML body, mitochondrion	positive regulation of gene-specific transcription from RNA polymerase II promoter, senescence, mitotic cell cycle G1/S DNA damage checkpoint, cell cycle arrest, regulation of mitochondrial membrane permeability, response to gamma radiation, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, response to tumor cell, ER overload response, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, interspecies interaction between organisms, Ras protein signal transduction, nucleotide-excision repair, protein tetramerization, cellular response to glucose starvation, negative regulation of helicase activity, negative regulation of cell growth, base-excision repair, activation of caspase activity by cytochrome c, cell aging

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	33	WKLLPENNVLSPLPSQAMDDL	CDK_group	9372954	LTP	0.88	MOD_GSK3_1	PIN1 WW	-	0.56	-	-

Substrate:

PCTAIRE1 (Serine/threonine-protein kinase PCTAIRE-1)

Seq-ID:

Q00536 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cyclin-dependent protein kinase activity, ATP binding, protein binding		protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	95	ASATSSDEVQSPVRVRMRNHP	CDK_group	12084709	LTP	0.80	MOD_CDK_SPxK_1	-	-	0.82	-	medium

Substrate:

PP1A (ser/thr protein phosphatase PP1-alpha 1 catalytic subunit (from PhosphoBase))

Seq-ID:

P62136 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48444   M3K3_HUMAN
MINT-62187   NOM1_HUMAN
MINT-62188   PP1R8_HUMAN
MINT-62189   PP1RA_HUMAN
MINT-62194   ASPP2_HUMAN
MINT-62195   STAM1_HUMAN
MINT-62197   KI18A_HUMAN
MINT-62199   NEB2_HUMAN
MINT-62200   PLCL2_HUMAN
MINT-62201   CASC5_HUMAN
MINT-62203   ASPP1_HUMAN
MINT-62204   MPP10_HUMAN
MINT-62205   ZFY16_HUMAN
MINT-62206   P53_HUMAN
MINT-4544575   AXN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, protein serine/threonine phosphatase activity, protein phosphatase type 1 regulator activity, protein binding	cytosol, MLL5-L complex, nucleolus	cell division, cell cycle, protein amino acid dephosphorylation, glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	320	SGLNPGGRPITPPRNSAKAKK	CDK_group	12202491	LTP	0.65	MOD_CDK_SPxK_1	-	-	0.70	-	medium

Substrate:

Presenilin 1 (Presenilin 1 (PS-1) (S182 protein))

Seq-ID:

P49768 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14193   PKP4_HUMAN
MINT-15987   FLNB_HUMAN
MINT-16205   B2CL1_HUMAN
MINT-17726   FLNA_HUMAN
MINT-49819   CADH1_HUMAN
MINT-2837737   GSK3B_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium channel activity, beta-catenin binding, endopeptidase activity, PDZ domain binding	centrosome, Golgi membrane, smooth endoplasmic reticulum, integral to plasma membrane, cell surface, kinetochore, nuclear outer membrane, endoplasmic reticulum membrane, rough endoplasmic reticulum, gamma-secretase complex	induction of apoptosis by extracellular signals, membrane protein ectodomain proteolysis, anti-apoptosis, Notch receptor processing, membrane protein intracellular domain proteolysis, Notch signaling pathway, amyloid precursor protein catabolic process, cell-cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	354	RDSHLGPHRSTPESRAAVQEL	CDK_group	12056836	LTP	0.11		-	PSN	0.58	-	medium

Substrate:

Ras-related protein Rab-4A (ras-related protein Rab-4A (from PhosphoBase))

Seq-ID:

P20338 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-63547 P53_HUMAN
MINT-63548 SRA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GDP binding, GTPase activity, GTP binding		small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	199	YGDAALRQLRSPRRAQAPNAQ	CDK_group	1425574	LTP	0.50	MOD_CDK_SPxK_1	-	-	0.46	-	medium

Substrate:

RB (retinoblastoma-associated protein (pp110) (p105-RB) (RB) (from PhosphoBase))

Seq-ID:

P06400 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13924   CUX1_HUMAN
MINT-25007   LT_SV40
MINT-73396   HDAC2_HUMAN
MINT-77770   MCM7_HUMAN
MINT-1776635   MDM2_HUMAN
MINT-4793646   E2F2_HUMAN
MINT-4793665   E2F1_HUMAN
MINT-4793727   CHK2_HUMAN
MINT-4793746   CHK1_HUMAN
MINT-4793793   MK14_HUMAN
MINT-6628399   E2F3_HUMAN
MINT-6628404   HDAC1_HUMAN
MINT-6628409   RBBP8_HUMAN
MINT-6665112   E1A_ADE05
MINT-7384113   VE7_HPV16

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, ubiquitin protein ligase binding, androgen receptor binding, kinase binding, transcription coactivator activity, sequence-specific DNA binding transcription factor activity, phosphoprotein binding	chromatin, Rb-E2F complex, SWI/SNF complex, PML body	negative regulation of transcription factor activity, transcription, mitotic cell cycle G1/S transition checkpoint, regulation of transcription involved in G1/S phase of mitotic cell cycle, negative regulation of cell growth, cell cycle arrest, regulation of lipid kinase activity, G1 phase, negative regulation of S phase of mitotic cell cycle, myoblast differentiation, M phase, androgen receptor signaling pathway, chromatin remodeling, interspecies interaction between organisms, Ras protein signal transduction, negative regulation of protein kinase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	249	YKTAVIPINGSPRTPRRGQNR	CDK_group	1756735	LTP	0.08	MOD_CDK_SPxK_1	-	-	0.51	-	-
T	252	AVIPINGSPRTPRRGQNRSAR	CDK_group	1756735	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.52	-	-
T	373	DEEVNVIPPHTPVRTVMNTIQ	CDK_group	1756735	LTP	1.00	MOD_CDK_SPxK_1	-	RB_A	0.42	-	-
S	807	LRIPGGNIYISPLKSPYKISE	CDK_group	1756735	LTP	1.00	MOD_CDK_SPxK_1	-	Rb_C	0.29	-	-
S	811	GGNIYISPLKSPYKISEGLPT	CDK_group	1756735	LTP	1.00	MOD_CDK_SPxK_1	-	Rb_C	0.34	-	-

Substrate:

Retinoblastoma like 2 (Cell cycle control protein)

Seq-ID:

Q08999 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16160   RBBP8_HUMAN
MINT-68815   VE7_HPV16
MINT-6665139   E1A_ADE05

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding, protein binding		chromatin modification, transcription, regulation of transcription, cell cycle, regulation of lipid kinase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	413	LTGVRYIKENSPCVTPVSTAT	CDK_group	11157749	LTP	0.05		-	-	0.38	-	medium
T	417	RYIKENSPCVTPVSTATHSLS	CDK_group	11157749	LTP	1.00		-	RB_A	0.40	-	medium
T	642	DEICIAGSPLTPRRVTEVRAD	CDK_group	11157749	LTP	0.21	MOD_CDK_SPxK_1	-	-	0.46	-	medium
S	662	DTGGLGRSITSPTTLYDRYSS	CDK_group	11157749	LTP	0.24		-	-	0.57	-	medium
S	688	TRRRLFVENDSPSDGGTPGRM	CDK_group	11157749	LTP	0.20		-	-	0.86	-	medium
T	694	VENDSPSDGGTPGRMPPQPLV	CDK_group	11157749	LTP	0.23	MOD_CDK_SPxK_1	-	-	0.89	-	medium
S	1044	LSPYPFVRTGSPRRIQLSQNH	CDK_group	11157749	LTP	0.28	MOD_CDK_SPxK_1	-	-	0.63	-	medium
S	1068	ISPHKNETMLSPREKIFYYFS	CDK_group	11157749	LTP	0.20		-	-	0.40	-	medium
S	1080	REKIFYYFSNSPSKRLREINS	CDK_group	11157749	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.34	-	medium
T	1097	EINSMIRTGETPTKKRGILLE	CDK_group	11157749	LTP	0.18	MOD_CDK_SPxK_1	-	-	0.56	-	medium
S	1112	RGILLEDGSESPAKRICPENH	CDK_group	11157749	LTP	1.00	MOD_CDK_SPxK_1	-	-	0.54	-	medium

Substrate:

Ribonucleotide reductase M2 subunit (Cell cycle control protein)

Seq-ID:

P11157 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transition metal ion binding, ribonucleoside-diphosphate reductase activity, protein binding	cytoplasm	oxidation reduction, protein heterotetramerization, deoxyribonucleotide biosynthetic process, DNA replication, deoxyribonucleoside diphosphate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	20	TIADQQQLQLSPLKRLTLADK	CDK_group	9990288	LTP	0.30	MOD_CDK_SPxK_1	-	-	0.43	-	low

Substrate:

Serine/threonine protein phosphatase PP1-1 (serine/threonine protein phosphatase PP1-1 (EC 3.1.3.16) (from PhosphoBase))

Seq-ID:

P13681 [Schizosaccharomyces pombe]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, phosphoprotein phosphatase activity	cytosol, mRNA cleavage and polyadenylation specificity factor complex	cell division, regulation of homologous chromosome segregation, protein amino acid dephosphorylation, DNA damage checkpoint, mitosis, regulation of mitotic sister chromatid segregation, microtubule cytoskeleton organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	316	YQGSSQNWHMTPPRKNKTGNS	CDK_group	7957097	LTP	0.35	MOD_CDK_SPxK_1	-	-	0.72	-	low

Substrate:

Serine/threonine-protein kinase PAK 1 (Ser/Thr protein kinase family)

Seq-ID:

Q13153 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14030   CDC42_HUMAN
MINT-61476   NCK1_HUMAN
MINT-1771821   CD11B_HUMAN
MINT-1953519   GIT1_HUMAN
MINT-1953555   GIT2_HUMAN
MINT-3389399   RAF1_HUMAN
MINT-6541935   SRC8_HUMAN
MINT-7211888   SH3K1_HUMAN
MINT-7212697   ARHG7_HUMAN
MINT-7217644   RAC1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, collagen binding, ATP binding	focal adhesion, cytosol, Golgi apparatus	ER-nucleus signaling pathway, apoptosis, positive regulation of JUN kinase activity, protein amino acid autophosphorylation, cytoskeleton organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	212	TRSVIEPLPVTPTRDVATSPI	CDK_group	11604394	LTP	0.12	MOD_CDK_SPxK_1	-	-	0.68	-	-

Substrate:

Src (Proto-oncogene tyrosine-protein kinase Src)

Seq-ID:

P00523 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15440   HNRPK_RAT
MINT-16809   KHDR1_HUMAN
MINT-17269   SHC1_HUMAN
MINT-7212640   HCN2_MOUSE
MINT-7306585   LCP2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
non-membrane spanning protein tyrosine kinase activity, ATP binding		signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	34	THHGGFPASQTPNKTAAPDTH	CDK_group	1956339	LTP	0.24	MOD_CDK_SPxK_1	-	-	0.89	-	-
T	46	NKTAAPDTHRTPSRSFGTVAT	CDK_group	1956339	LTP	0.23	MOD_CDK_SPxK_1	-	-	0.80	-	-
S	72	GGFNTSDTVTSPQRAGALAGG	CDK_group	1956339	LTP	0.21	MOD_CDK_SPxK_1	-	-	0.62	-	-

Substrate:

Src (Proto-oncogene tyrosine-protein kinase Src)

Seq-ID:

P12931 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14765   DDR2_HUMAN
MINT-15459   CAV1_HUMAN
MINT-46002   CTNB1_MOUSE
MINT-50376   RASH_HUMAN
MINT-62340   KPCD_HUMAN
MINT-62342   CDCP1_HUMAN
MINT-65953   DYN1_HUMAN
MINT-65954   DYN2_HUMAN
MINT-68512   PDC6I_HUMAN
MINT-74753   ERBB3_HUMAN
MINT-2792760   PAK2_HUMAN
MINT-2793013   ADA15_HUMAN
MINT-2840132   TLR3_HUMAN
MINT-3381308   FAK1_HUMAN
MINT-3381360   FYN_HUMAN
MINT-4051815   ADRB2_HUMAN
MINT-4961196   AFAD_HUMAN
MINT-4980122   SNIP_MOUSE
MINT-5210599   SNIP_HUMAN
MINT-6539730   CBL_HUMAN
MINT-6771405   FAK1_MOUSE
MINT-6794909   ACTS_HUMAN
MINT-6795322   ACTN1_HUMAN
MINT-6795447   PTN1_HUMAN
MINT-7035260   HNRPK_HUMAN
MINT-7040283   CBLB_HUMAN
MINT-7104422   BCAR1_HUMAN
MINT-7145938   RL10_HUMAN
MINT-7244986   ASAP1_HUMAN
MINT-7244998   FANCA_HUMAN
MINT-7245022   PHAR2_HUMAN
MINT-7245034   ABL1_HUMAN
MINT-7245058   DLGP4_HUMAN
MINT-7245070   SNX17_HUMAN
MINT-7245106   RTN4_HUMAN
MINT-7245118   ASAP2_HUMAN
MINT-7245142   E41L3_HUMAN
MINT-7245154   ICAL_HUMAN
MINT-7245214   FCG2B_HUMAN
MINT-7245226   FCG2C_HUMAN
MINT-7245334   SHAN2_HUMAN
MINT-7245346   SHRM2_HUMAN
MINT-7245358   DNLI3_HUMAN
MINT-7245370   EIF3D_HUMAN
MINT-7245406   HCN2_HUMAN
MINT-7245490   CKAP5_HUMAN
MINT-7245502   M4K1_HUMAN
MINT-7245538   RPP38_HUMAN
MINT-7245562   SP1_HUMAN
MINT-7245574   DOCK1_HUMAN
MINT-7245586   RLGPB_HUMAN
MINT-7245598   ABL2_HUMAN
MINT-7245610   CELR2_HUMAN
MINT-7245622   SOS1_HUMAN
MINT-7245634   AKAP6_HUMAN
MINT-7245670   DPOD1_HUMAN
MINT-7245682   DAG1_HUMAN
MINT-7245694   SNX3_HUMAN
MINT-7245730   KI67_HUMAN
MINT-7245742   CD97_HUMAN
MINT-7245754   RPGF1_HUMAN
MINT-7245778   ACAP1_HUMAN
MINT-7245790   PRIC3_HUMAN
MINT-7245814   AKAP2_HUMAN
MINT-7245826   RRAS_HUMAN
MINT-7296136   P85A_HUMAN
MINT-7296149   ACTB_HUMAN
MINT-7306598   LCP2_HUMAN
MINT-7552515   PTPRA_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3/SH2 adaptor activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, integrin binding, SH2 domain binding	caveola, cytosol	protein amino acid phosphorylation, regulation of bone resorption, signal complex assembly, regulation of vascular permeability, response to interleukin-1, interspecies interaction between organisms, Ras protein signal transduction, positive regulation of integrin activation, intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	75	GGFNSSDTVTSPQRAGPLAGG	CDK_group	10544291	LTP	0.14	MOD_CDK_SPxK_1	-	-	0.64	-	-

Substrate:

Stathmin (stathmin (phosphoprotein p19) (oncoprotein 18) (Op18) (from PhosphoBase))

Seq-ID:

P16949 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-2860477 UBQL4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
signal transducer activity, tubulin binding	cytoplasm, microtubule	intracellular signaling pathway, nervous system development, mitotic spindle organization, cell differentiation, microtubule depolymerization, response to virus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	38	SKESVPEFPLSPPKKKDLSLE	CDK_group	8325881	LTP	0.59	MOD_CDK_SPxK_1	-	Stathmin	0.69	-	medium

Substrate:

Stathmin (stathmin (phosphoprotein p19) (oncoprotein 18) (Op18) (from PhosphoBase))

Seq-ID:

P54227 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cytoplasm, microtubule	positive regulation of cellular component movement, negative regulation of microtubule polymerization, axonogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	25	ASGQAFELILSPRSKESVPDF	CDK_group	8376365	LTP	0.28		-	Stathmin	0.54	-	low
S	38	SKESVPDFPLSPPKKKDLSLE	CDK_group	8376365	LTP	0.53	MOD_CDK_SPxK_1	-	Stathmin	0.70	-	low

Substrate:

SWI5 (transcriptional factor SWI5 (from PhosphoBase))

Seq-ID:

P08153 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, transcription activator activity, zinc ion binding, protein binding	cytoplasm, nucleus	transcription, regulation of transcription involved in G1 phase of mitotic cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	522	IKEINTYTTNSPSKITRKLTT	CDK_group	1652372	LTP	0.24	MOD_CDK_SPxK_1	-	-	0.57	-	medium
S	646	KKYENVVIKRSPRKRGRPRKD	CDK_group	1652372	LTP	0.22	MOD_CDK_SPxK_1	-	-	0.75	-	medium
S	664	RKDGTSSVSSSPIKENINKDH	CDK_group	1652372	LTP	0.37	MOD_CDK_SPxK_1	-	-	0.79	-	medium

Substrate:

Synapsin-1 (Synapsin I (Brain protein 4.1))

Seq-ID:

P17599 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
catalytic activity, ATP binding, actin binding	synaptonemal complex, cell junction, synaptic vesicle membrane, Golgi apparatus	neurotransmitter secretion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	551	GAPPATRPPASPSPQRQAGPP	CDK_group	2108963	LTP	0.62	MOD_CDK_SPxK_1	-	-	0.99	-	low
S	553	PPATRPPASPSPQRQAGPPQA	CDK_group	8702879	LTP	0.20	MOD_CDK_SPxK_1	-	-	0.99	-	low

Substrate:

Synapsin-1 (Synapsin I (Brain protein 4.1))

Seq-ID:

P17600 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-63519 VIME_HUMAN
MINT-63520 KAT5_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
catalytic activity, ATP binding, actin binding, transporter activity	cell junction, Golgi apparatus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	551	GAPPAARPPASPSPQRQAGPP	CDK_group	8702879	LTP	0.52	MOD_CDK_SPxK_1	-	-	0.99	-	medium

Substrate:

Syntaxin binding protein 1 (Syntaxin binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (rbSec1) (p67))

Seq-ID:

P61763 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	mitochondrion, membrane	vesicle docking involved in exocytosis, synaptic vesicle maturation, protein transport, axon target recognition

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	158	DSADSFQSFYSPHKAQMKNPI	CDK_group	9478941	LTP	1.00	MOD_CDK_SPxK_1	-	Sec1	0.32	3C98	1.64%
T	574	EVLIGSTHILTPQKLLDTLKK	CDK_group	9478941	LTP	0.98	MOD_CDK_SPxK_1	-	Sec1	0.19	3C98	11.64%

Substrate:

tau (Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau))

Seq-ID:

P10636 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-49642   AATF_HUMAN
MINT-74874   KS6B1_HUMAN
MINT-3390085   KC1D_RAT
MINT-3974182   CDK5_HUMAN
MINT-3974216   GSK3B_HUMAN
MINT-7148384   EAA2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
apolipoprotein E binding, SH3 domain binding, lipoprotein binding, identical protein binding, structural constituent of cytoskeleton, enzyme binding, microtubule binding	plasma membrane, cytosol, microtubule associated complex, tubulin complex, axon, growth cone, microtubule	positive regulation of microtubule polymerization, superior temporal gyrus development, negative regulation of microtubule depolymerization, positive regulation of axon extension, microtubule cytoskeleton organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	519	GDRSGYSSPGSPGTPGSRSRT	CDK_group	12226093	LTP	1.00		-	-	0.95	-	medium
T	522	SGYSSPGSPGTPGSRSRTPSL	CDK_group	12226093	LTP	1.00		-	-	0.95	-	medium
T	529	SPGTPGSRSRTPSLPTPPTRE	CDK_group	11181841	LTP	0.84		-	-	0.97	-	medium
T	529	SPGTPGSRSRTPSLPTPPTRE	CDK_group	2387894	LTP	0.84		-	-	0.97	-	medium
T	534	GSRSRTPSLPTPPTREPKKVA	CDK_group	11181841	LTP	1.00		-	-	0.94	-	medium
T	534	GSRSRTPSLPTPPTREPKKVA	CDK_group	2387894	LTP	1.00		-	-	0.94	-	medium
T	548	REPKKVAVVRTPPKSPSSAKS	CDK_group	12387894	LTP	1.00	MOD_GSK3_1	-	-	0.89	-	medium
T	548	REPKKVAVVRTPPKSPSSAKS	CDK_group	9735171	LTP	1.00	MOD_GSK3_1	-	-	0.89	-	medium
S	552	KVAVVRTPPKSPSSAKSRLQT	CDK_group	12387894	LTP	1.00	MOD_GSK3_1	-	-	0.87	-	medium
T	690	VPGGGNKKIETHKLTFRENAK	CDK_group	12387894	LTP	0.80		-	-	0.61	-	medium
S	713	TDHGAEIVYKSPVVSGDTSPR	CDK_group	12387894	LTP	1.00	MOD_GSK3_1	-	-	0.57	-	medium
S	713	TDHGAEIVYKSPVVSGDTSPR	CDK_group	11181841	LTP	1.00	MOD_GSK3_1	-	-	0.57	-	medium
S	721	YKSPVVSGDTSPRHLSNVSST	CDK_group	12387894	LTP	1.00	MOD_GSK3_1	-	-	0.61	-	medium
S	721	YKSPVVSGDTSPRHLSNVSST	CDK_group	11181841	LTP	1.00	MOD_GSK3_1	-	-	0.61	-	medium

Substrate:

Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))

Seq-ID:

P04177 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amino acid binding, tyrosine 3-monooxygenase activity, ferrous iron binding, ferric iron binding, dopamine binding	mitochondrion, cytosol, synaptic vesicle, terminal button	neurotransmitter biosynthetic process, oxidation reduction, response to hypoxia, response to steroid hormone stimulus, protein homotetramerization, dopamine biosynthetic process from tyrosine

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	MPTPSAPSPQPKGFRRAV	CDK_group	2570779	LTP	0.36		-	-	0.86	-	medium

Substrate:

Tyrosine-protein phosphatase, non-receptor type 1 (Protein tyrosine phosphatase 1B)

Seq-ID:

P18031 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51115   PPIP1_HUMAN
MINT-73489   CADH2_HUMAN
MINT-6744190   CSK21_HUMAN
MINT-6761890   GSK3B_HUMAN
MINT-6761899   ESR1_HUMAN
MINT-6762163   IKBA_HUMAN
MINT-6762380   PGFRB_HUMAN
MINT-6762549   PAXI_MOUSE
MINT-6762573   FAK1_MOUSE
MINT-6762866   IRS1_RAT
MINT-6763504   BCAR1_MOUSE
MINT-6763556   INSR_RAT
MINT-6764602   JAK2_HUMAN
MINT-6764613   STAT3_HUMAN
MINT-6764665   TRPV6_HUMAN
MINT-6764866   CAV1_HUMAN
MINT-6765163   PIAS1_HUMAN
MINT-6765185   SUMO1_HUMAN
MINT-6765318   CTND1_MOUSE
MINT-6765333   LPP_MOUSE
MINT-6765355   SRC8_MOUSE
MINT-6765370   ZO1_MOUSE
MINT-6765383   PLCG1_MOUSE
MINT-6765422   DOK1_MOUSE
MINT-6765439   EGFR_MOUSE
MINT-6765460   PGFRB_MOUSE
MINT-6787689   MET_HUMAN
MINT-6787710   ABL1_HUMAN
MINT-6793324   B3AT_HUMAN
MINT-6793358   EGFR_HUMAN
MINT-6793387   CAN1_HUMAN
MINT-6793394   CAN2_HUMAN
MINT-6793439   IRS1_MOUSE
MINT-6793452   INSR_MOUSE
MINT-6793484   BCAR1_HUMAN
MINT-6793722   AKT1_MOUSE
MINT-6793745   IRS1_HUMAN
MINT-6793782   TYK2_HUMAN
MINT-6793941   NTRK1_HUMAN
MINT-6793957   NTRK3_HUMAN
MINT-6793973   LTK_HUMAN
MINT-6793989   STA5A_HUMAN
MINT-6794005   STA5B_HUMAN
MINT-6794135   LAT_HUMAN
MINT-6794748   EPOR_HUMAN
MINT-6794792   GRB2_HUMAN
MINT-6794817   ITB3_HUMAN
MINT-6794878   ACTS_HUMAN
MINT-6794892   FAK1_HUMAN
MINT-6794946   INSR_HUMAN
MINT-6794972   KPCG_HUMAN
MINT-6795050   JAK2_MOUSE
MINT-6795199   SRC8_HUMAN
MINT-6795447   SRC_HUMAN
MINT-6796717   PLD2_HUMAN
MINT-6797067   CLK2_HUMAN
MINT-6797829   GHR_HUMAN
MINT-6799814   ROS_HUMAN
MINT-6800783   IGF1R_HUMAN
MINT-7972220   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein tyrosine phosphatase activity, zinc ion binding	cytosol, endoplasmic reticulum membrane	negative regulation of insulin receptor signaling pathway, signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	386	GGSLRGAQAASPAKGEPSLPE	CDK_group	8491187	LTP	0.00	MOD_CDK_SPxK_1	-	-	0.75	-	-

Substrate:

Vimentin (vimentin (from PhosphoBase))

Seq-ID:

P20152 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19723 ARRB1_HUMAN
MINT-50699 KPCE_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytoplasm, type III intermediate filament, cell leading edge	intermediate filament-based process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	56	PSTSRSLYSSSPGGAYVTRSS	CDK_group	7983050	LTP	0.48		-	Filament_head	0.51	-	medium