List of substrates found:

Vav  SYK  SH2 domain protein 2A  ZAP70  CD3 epsilon  CD3 delta  Ras GTPase-activating protein 1  P130Cas  EGFR  SH3 domain-binding protein 2  CD5  CD3 gamma  LCK  Tyrosine-protein phosphatase, non-receptor type 6  CD45  c-met  CD3 zeta  Src 


Substrate: Vav (Adaptor molecule. GDP/GTP exchange factor in Rho/Rac molecule)
Seq-ID: P15498 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 142 EEESVGDEDIYSGLSDQIDDT Lck 16285729
LTP
1.00
Lck SH2 -
0.49
- medium

Substrate: SYK (Spleen tyrosine kinase )
Seq-ID: P43405 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 348 REALPMDTEVYESPYADPEEI SYK 8657103
LTP
0.93
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.59
--
Y 348 REALPMDTEVYESPYADPEEI - 12522270
HTP
0.93
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.59
--
Y 348 REALPMDTEVYESPYADPEEI - 18083107
HTP
0.93
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.59
--
Y 352 PMDTEVYESPYADPEEIRPKE SYK 8657103
LTP
1.00
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.53
--
Y 352 PMDTEVYESPYADPEEIRPKE - 12522270
HTP
1.00
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.53
--
Y 352 PMDTEVYESPYADPEEIRPKE - 18083107
HTP
1.00
FGR SH2;
Lck SH2;
PLCG1 SH2;
VAV1 SH2
-
0.53
--
Y 525 LSKALRADENYYKAQTHGKWP SYK 8657103
LTP
1.00
CBL PTB;
Lck SH2
TyrKc
0.19
1XBA 41.92%
Y 526 SKALRADENYYKAQTHGKWPV SYK 8657103
LTP
1.00
CBL PTB;
Lck SH2
TyrKc
0.17
1XBA 30.57%
Y 526 SKALRADENYYKAQTHGKWPV - 18083107
HTP
1.00
CBL PTB;
Lck SH2
TyrKc
0.17
1XBA 30.57%

Substrate: SH2 domain protein 2A (Adapter molecule)
Seq-ID: Q9NP31 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 280 APRPKPSNPIYNEPDEPIAFY - 16497976
HTP
0.09
Lck SH2 -
0.77
- low
Y 290 YNEPDEPIAFYAMGRGSPGEA - 16497976
HTP
0.16
Lck SH2 -
0.76
- low
Y 305 GSPGEAPSNIYVEVEDEGLPA - 15592455
HTP
0.16
Lck SH2 -
0.76
- low

Substrate: ZAP70 (Cytoplasmic tyrosine kinase)
Seq-ID: P43403 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 319 PMDTSVYESPYSDPEELKDKK - 10202147
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 10318843
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 12522270
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15592455
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 16094384
HTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 10037717
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15268851
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%
Y 319 PMDTSVYESPYSDPEELKDKK - 15292262
LTP
1.00
CRKL SH2;
CRK SH2;
Lck SH2;
PLCG1 SH2;
PLCG_group SH2
-
0.52
2OZO 1.83%

Substrate: CD3 epsilon (T cell surface glycoprotein)
Seq-ID: P07766 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 188 ERPPPVPNPDYEPIRKGQRDL - 15592455
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.67
- medium
Y 188 ERPPPVPNPDYEPIRKGQRDL - 16094384
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.67
- medium
Y 188 ERPPPVPNPDYEPIRKGQRDL - 15659558
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.67
- medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 12522270
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.40
- medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15144186
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.40
- medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15592455
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.40
- medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 16094384
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.40
- medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15659558
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.40
- medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 18083107
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.40
- medium

Substrate: CD3 delta (T cell surface glycoprotein)
Seq-ID: P04234 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 149 TQALLRNDQVYQPLRDRDDAQ - 12522270
HTP
1.00
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.36
- low
Y 149 TQALLRNDQVYQPLRDRDDAQ - 15144186
HTP
1.00
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.36
- low
Y 149 TQALLRNDQVYQPLRDRDDAQ - 15592455
HTP
1.00
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.36
- low
Y 149 TQALLRNDQVYQPLRDRDDAQ - 16094384
HTP
1.00
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.36
- low
Y 149 TQALLRNDQVYQPLRDRDDAQ - 15659558
HTP
1.00
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.36
- low

Substrate: Ras GTPase-activating protein 1 (Ras p21 activator protein (GAP))
Seq-ID: P20936 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 460 LNDTVDGKEIYNTIRRKTKDA PDGFR_group 1850098
LTP
1.00
Lck SH2;
Src SH2
-
0.31
- low
Y 460 LNDTVDGKEIYNTIRRKTKDA EGFR 1850098
LTP
1.00
Lck SH2;
Src SH2
-
0.31
- low

Substrate: P130Cas (Adaptor molecule. Contain 15 YxxP motifs. )
Seq-ID: P56945 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 664 ENSEGGWMEDYDYVHLQGKEE - 8621540
LTP
1.00
FES SH2;
Fyn SH2;
Lck SH2;
Src SH2
-
0.49
- medium
Y 664 ENSEGGWMEDYDYVHLQGKEE - 11604500
LTP
1.00
FES SH2;
Fyn SH2;
Lck SH2;
Src SH2
-
0.49
- medium

Substrate: EGFR (Receptor for EGF and other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor,)
Seq-ID: P00533 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1092 IDDTFLPVPEYINQSVPKRPA EGFR 8845374
LTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1092 IDDTFLPVPEYINQSVPKRPA - 15302935
HTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1092 IDDTFLPVPEYINQSVPKRPA - 17081983
HTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1092 IDDTFLPVPEYINQSVPKRPA - 18083107
HTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--

Substrate: SH3 domain-binding protein 2 (Adaptor molecule)
Seq-ID: Q06649 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 446 DTGEEDSDEDYEKVPLPNSVF - 12709437
LTP
1.00
Lck SH2;
Lyn SH2;
VAV1 SH2
-
0.70
- low

Substrate: CD5 (T-cell surface glycoprotein CD5 precursor (Lymphocyte glycoprotein T1/Leu-1) (Lymphocyte antigen CD5))
Seq-ID: P06127 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
scavenger receptor activity integral to plasma membrane cell recognition,
cell proliferation
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 453 NPTASHVDNEYSQPPRNSRLS - 12522270
HTP
1.00
Lck SH2;
RASA_group SH2
-
0.71
- medium
Y 453 NPTASHVDNEYSQPPRNSRLS - 15144186
HTP
1.00
Lck SH2;
RASA_group SH2
-
0.71
- medium
Y 453 NPTASHVDNEYSQPPRNSRLS Lck 11298344
LTP
1.00
Lck SH2;
RASA_group SH2
-
0.71
- medium
Y 453 NPTASHVDNEYSQPPRNSRLS - 15659558
HTP
1.00
Lck SH2;
RASA_group SH2
-
0.71
- medium
Y 465 QPPRNSRLSAYPALEGVLHRS - 11751967
LTP
1.00
Lck SH2 -
0.49
- medium
Y 487 MQPDNSSDSDYDLHGAQRL   Lck 11298344
LTP
1.00
Lck SH2 -
0.70
- medium

Substrate: CD3 gamma (T-cell surface glycoprotein CD3 gamma chain (T3 gamma chain) (from PhosphoBase))
Seq-ID: P09693 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 160 KQTLLPNDQLYQPLKDREDDQ - 16094384
HTP
0.95
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.48
- low

Substrate: LCK (proto-oncogene tyrosine-protein kinase Lck (from PhosphoBase))
Seq-ID: P06239 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 505 EDFFTATEGQYQPQP       - 3265417
LTP
0.96
Lck SH2;
Src SH2;
SYK SH2
-
0.49
--
Y 505 EDFFTATEGQYQPQP       - 15592455
HTP
0.96
Lck SH2;
Src SH2;
SYK SH2
-
0.49
--
Y 505 EDFFTATEGQYQPQP       Lck 8945479
LTP
0.96
Lck SH2;
Src SH2;
SYK SH2
-
0.49
--
Y 505 EDFFTATEGQYQPQP       - 17192257
HTP
0.96
Lck SH2;
Src SH2;
SYK SH2
-
0.49
--
Y 505 EDFFTATEGQYQPQP       - 18083107
HTP
0.96
Lck SH2;
Src SH2;
SYK SH2
-
0.49
--

Substrate: Tyrosine-protein phosphatase, non-receptor type 6 (Protein tyrosine phosphatase containing SH2 domains)
Seq-ID: P29350 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 536 LQSQKGQESEYGNITYPPAMK - 12468540
LTP
1.00
Lck SH2;
Src SH2
-
0.56
- low
Y 536 LQSQKGQESEYGNITYPPAMK Lck 8114715
LTP
1.00
Lck SH2;
Src SH2
-
0.56
- low
Y 536 LQSQKGQESEYGNITYPPAMK Abl 8692915
LTP
1.00
Lck SH2;
Src SH2
-
0.56
- low
Y 536 LQSQKGQESEYGNITYPPAMK - 7512963
LTP
1.00
Lck SH2;
Src SH2
-
0.56
- low
Y 536 LQSQKGQESEYGNITYPPAMK - 14757045
LTP
1.00
Lck SH2;
Src SH2
-
0.56
- low
Y 536 LQSQKGQESEYGNITYPPAMK SRC 14699166
LTP
1.00
Lck SH2;
Src SH2
-
0.56
- low
Y 536 LQSQKGQESEYGNITYPPAMK - 18083107
HTP
1.00
Lck SH2;
Src SH2
-
0.56
- low

Substrate: CD45 (Receptor tyrosine phosphatase)
Seq-ID: P08575 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1216 RPGMVSTFEQYQFLYDVIAST Csk 7507203
LTP
1.00
Lck SH2 PTPc
0.26
- medium

Substrate: c-met (Receptor tyrosine kinase for hepatocyte growth factor.)
Seq-ID: P08581 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 12475979
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9444958
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9252406
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 7513258
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7731718
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7687741
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9826708
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%

Substrate: CD3 zeta (T-cell surface glycoprotein CD3 zeta chain precursor (from PhosphoBase))
Seq-ID: P20963 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 72 PAYQQGQNQLYNELNLGRREE - 15144186
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.44
- medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15592455
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.44
- medium
Y 72 PAYQQGQNQLYNELNLGRREE - 16094384
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.44
- medium
Y 72 PAYQQGQNQLYNELNLGRREE - 15659558
HTP
1.00
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.44
- medium
Y 83 NELNLGRREEYDVLDKRRGRD - 12522270
HTP
1.00
Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.47
- medium
Y 83 NELNLGRREEYDVLDKRRGRD - 15592455
HTP
1.00
Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.47
- medium
Y 83 NELNLGRREEYDVLDKRRGRD - 16094384
HTP
1.00
Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.47
- medium
Y 83 NELNLGRREEYDVLDKRRGRD - 15659558
HTP
1.00
Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.47
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE Fyn 8578591
LTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 12522270
HTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15144186
HTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15592455
HTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 16094384
HTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 15659558
HTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 111 QRRKNPQEGLYNELQKDKMAE - 18083107
HTP
1.00
LIG_TYR_ITAM
Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.63
- medium
Y 123 ELQKDKMAEAYSEIGMKGERR Fyn 8578591
LTP
1.00
LIG_TYR_ITAM
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.49
- medium
Y 123 ELQKDKMAEAYSEIGMKGERR - 12522270
HTP
1.00
LIG_TYR_ITAM
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.49
- medium
Y 123 ELQKDKMAEAYSEIGMKGERR - 16094384
HTP
1.00
LIG_TYR_ITAM
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.49
- medium
Y 123 ELQKDKMAEAYSEIGMKGERR - 15659558
HTP
1.00
LIG_TYR_ITAM
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.49
- medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 12522270
HTP
1.00
Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.65
- medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 15592455
HTP
1.00
Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.65
- medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 16094384
HTP
1.00
Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.65
- medium
Y 142 RRRGKGHDGLYQGLSTATKDT - 15659558
HTP
1.00
Fyn SH2;
Lck SH2;
PLCG1 SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.65
- medium
Y 153 QGLSTATKDTYDALHMQALPP - 16094384
HTP
0.90
Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.65
- medium
Y 153 QGLSTATKDTYDALHMQALPP - 15659558
HTP
0.90
Fyn SH2;
Lck SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.65
- medium

Substrate: Src (Proto-oncogene tyrosine-protein kinase Src)
Seq-ID: P12931 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14765   DDR2_HUMAN
MINT-15459   CAV1_HUMAN
MINT-46002   CTNB1_MOUSE
MINT-50376   RASH_HUMAN
MINT-62340   KPCD_HUMAN
MINT-62342   CDCP1_HUMAN
MINT-65953   DYN1_HUMAN
MINT-65954   DYN2_HUMAN
MINT-68512   PDC6I_HUMAN
MINT-74753   ERBB3_HUMAN
MINT-2792760   PAK2_HUMAN
MINT-2793013   ADA15_HUMAN
MINT-2840132   TLR3_HUMAN
MINT-3381308   FAK1_HUMAN
MINT-3381360   FYN_HUMAN
MINT-4051815   ADRB2_HUMAN
MINT-4961196   AFAD_HUMAN
MINT-4980122   SNIP_MOUSE
MINT-5210599   SNIP_HUMAN
MINT-6539730   CBL_HUMAN
MINT-6771405   FAK1_MOUSE
MINT-6794909   ACTS_HUMAN
MINT-6795322   ACTN1_HUMAN
MINT-6795447   PTN1_HUMAN
MINT-7035260   HNRPK_HUMAN
MINT-7040283   CBLB_HUMAN
MINT-7104422   BCAR1_HUMAN
MINT-7145938   RL10_HUMAN
MINT-7244986   ASAP1_HUMAN
MINT-7244998   FANCA_HUMAN
MINT-7245022   PHAR2_HUMAN
MINT-7245034   ABL1_HUMAN
MINT-7245058   DLGP4_HUMAN
MINT-7245070   SNX17_HUMAN
MINT-7245106   RTN4_HUMAN
MINT-7245118   ASAP2_HUMAN
MINT-7245142   E41L3_HUMAN
MINT-7245154   ICAL_HUMAN
MINT-7245214   FCG2B_HUMAN
MINT-7245226   FCG2C_HUMAN
MINT-7245334   SHAN2_HUMAN
MINT-7245346   SHRM2_HUMAN
MINT-7245358   DNLI3_HUMAN
MINT-7245370   EIF3D_HUMAN
MINT-7245406   HCN2_HUMAN
MINT-7245490   CKAP5_HUMAN
MINT-7245502   M4K1_HUMAN
MINT-7245538   RPP38_HUMAN
MINT-7245562   SP1_HUMAN
MINT-7245574   DOCK1_HUMAN
MINT-7245586   RLGPB_HUMAN
MINT-7245598   ABL2_HUMAN
MINT-7245610   CELR2_HUMAN
MINT-7245622   SOS1_HUMAN
MINT-7245634   AKAP6_HUMAN
MINT-7245670   DPOD1_HUMAN
MINT-7245682   DAG1_HUMAN
MINT-7245694   SNX3_HUMAN
MINT-7245730   KI67_HUMAN
MINT-7245742   CD97_HUMAN
MINT-7245754   RPGF1_HUMAN
MINT-7245778   ACAP1_HUMAN
MINT-7245790   PRIC3_HUMAN
MINT-7245814   AKAP2_HUMAN
MINT-7245826   RRAS_HUMAN
MINT-7296136   P85A_HUMAN
MINT-7296149   ACTB_HUMAN
MINT-7306598   LCP2_HUMAN
MINT-7552515   PTPRA_MOUSE
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 530 EDYFTSTEPQYQPGENL     - 3103926
LTP
0.94
MOD_TYR_CSK
Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2
-
0.46
1FMK 18.34%
Y 530 EDYFTSTEPQYQPGENL     Csk 12468645
LTP
0.94
MOD_TYR_CSK
Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2
-
0.46
1FMK 18.34%
Y 530 EDYFTSTEPQYQPGENL     - 12387813
LTP
0.94
MOD_TYR_CSK
Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2
-
0.46
1FMK 18.34%


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