List of substrates found:

Acetylcholine receptor protein, delta chain  Ras GTPase-activating protein 1  Microtubule associated protein 2  Bcr  Insulin receptor substrate 1  Integrin beta 3  CSFR-1  FGFR-3  G-CSF-R  Ptpn11  R-PTP-alpha  c-kit  LAT  FAK  Insulin receptor substrate 2  CBL E3 ubiquitin protein ligase  P130Cas  ErbB4  EGFR  Shc  RET  CD136  PYK2  PDGF-R beta  LAT2  c-met  TIE2 (TEK)  CD28  VEGFR-1  SIT Protein  DOK3  Amyloid beta A4 protein  Beta-2 adrenergic receptor  TRKA  Insulin R  CD19  ErbB2 


Substrate: Acetylcholine receptor protein, delta chain (Acetylcholine receptor)
Seq-ID: P02718 [Torpedo californica]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 393 SVGYISKAQEYFNIKSRSELM - 1721053
LTP
0.37
GRB2 SH2 Neur_chan_memb
0.14
- medium
Y 393 SVGYISKAQEYFNIKSRSELM - 9185541
LTP
0.37
GRB2 SH2 Neur_chan_memb
0.14
- medium

Substrate: Ras GTPase-activating protein 1 (Ras p21 activator protein (GAP))
Seq-ID: P20936 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 615 KLPVKHFTNPYCNIYLNSVQV - 15592455
HTP
1.00
GRB2 SH2 C2
0.11
- low
Y 615 KLPVKHFTNPYCNIYLNSVQV - 18083107
HTP
1.00
GRB2 SH2 C2
0.11
- low

Substrate: Microtubule associated protein 2 (Cytoskeletal protein)
Seq-ID: P11137 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 67 AFGEHGSQGTYSNTKENGING Fyn 15536091
LTP
1.00
GRB2 SH2 -
0.85
- medium
Y 67 AFGEHGSQGTYSNTKENGING Lyn 15536091
LTP
1.00
GRB2 SH2 -
0.85
- medium

Substrate: Bcr (Breakpoint cluster region protein)
Seq-ID: P11274 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 177 QPGADAEKPFYVNVEFHHERG Fes 8955135
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG Fes 10405761
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 12522270
HTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 9178913
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 12124177
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 9407116
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG Abl 16912036
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG HCK 16912036
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 18083107
HTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 246 SESSCGVDGDYEDAELNPRFL Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2
-
0.57
- medium
Y 276 GSRPPWPPLEYQPYQSIYVGG Fes 8955135
LTP
0.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.58
- medium
Y 279 PPWPPLEYQPYQSIYVGGMME Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.58
- medium
Y 283 PLEYQPYQSIYVGGMMEGEGK Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.61
- medium

Substrate: Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)
Seq-ID: P35568 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 896 HPPEPKSPGEYVNIEFGSDQS - 11259577
LTP
1.00
GRB2 SH2;
PTPN11 SH2
-
0.76
--

Substrate: Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)
Seq-ID: P35570 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 895 HPPEPKSPGEYVNIEFGSGQP INSR 7504175
LTP
1.00
GRB2 SH2 -
0.80
- medium
Y 895 HPPEPKSPGEYVNIEFGSGQP IGF1R 8530377
LTP
1.00
GRB2 SH2 -
0.80
- medium
Y 895 HPPEPKSPGEYVNIEFGSGQP INSR 8530377
LTP
1.00
GRB2 SH2 -
0.80
- medium

Substrate: Integrin beta 3 (Platelet membrane glycoprotein IIIa)
Seq-ID: P05106 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 773 AKWDTANNPLYKEATSTFTNI - 8631894
LTP
1.00
GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB
Integrin_b_cyt
0.26
--
Y 773 AKWDTANNPLYKEATSTFTNI SRC 15699036
LTP
1.00
GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB
Integrin_b_cyt
0.26
--
Y 773 AKWDTANNPLYKEATSTFTNI - 18088087
HTP
1.00
GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB
Integrin_b_cyt
0.26
--
Y 773 AKWDTANNPLYKEATSTFTNI SRC 18398066
LTP
1.00
GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB
Integrin_b_cyt
0.26
--

Substrate: CSFR-1 (Macrophage colony stimulating factor I receptor)
Seq-ID: P07333 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 699 PGQDPEGGVDYKNIHLEKKYV - N.N.
LTP
1.00
GRAP2 SH2;
GRB2 SH2
TyrKc
0.45
- low

Substrate: FGFR-3 (Receptor tyrosine kinase)
Seq-ID: P22607 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 724 DKPANCTHDLYMIMRECWHAA FGFR3 11294897
LTP
1.00
GRB2 SH2;
SHC1 SH2
TyrKc
0.23
- medium

Substrate: G-CSF-R (Granulocyte colony stimulating factor receptor)
Seq-ID: P40223 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytokine receptor activity integral to membrane neutrophil chemotaxis,
cell adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 788 LGGPTPSPKSYENIWFHSRPQ - 8608222
LTP
1.00
GRB2 SH2;
PTPN11 SH2;
SHC_group SH2
-
0.60
- medium

Substrate: Ptpn11 (Protein-tyrosine phosphatase, non-receptor type 11)
Seq-ID: Q06124 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
non-membrane spanning protein tyrosine phosphatase activity cytosol
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 304 DGDPNEPVSDYINANIIMPEF - 12531430
LTP
1.00
GRB2 SH2 PTPc
0.45
3B7O 0.44%
Y 546 EQKSKRKGHEYTNIKYSLADQ - 11684012
LTP
1.00
GRB2 SH2 -
0.51
--
Y 546 EQKSKRKGHEYTNIKYSLADQ PDGFR_beta 8041791
LTP
1.00
GRB2 SH2 -
0.51
--
Y 546 EQKSKRKGHEYTNIKYSLADQ - 12531430
LTP
1.00
GRB2 SH2 -
0.51
--
Y 546 EQKSKRKGHEYTNIKYSLADQ - 12721296
LTP
1.00
GRB2 SH2 -
0.51
--

Substrate: R-PTP-alpha (Receptor tyrosine phosphatase)
Seq-ID: P18433 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 588 PVKRGEENTDYVNASFIDGYR - 7518772
LTP
1.00
GRB2 SH2 PTPc
0.33
1P15 1.31%
Y 798 VQEYIDAFSDYANFK       - 11923305
LTP
1.00
GRB2 SH2;
Src SH2
-
0.07
--
Y 798 VQEYIDAFSDYANFK       - 17507376
LTP
1.00
GRB2 SH2;
Src SH2
-
0.07
--
Y 798 VQEYIDAFSDYANFK       - 18083107
HTP
1.00
GRB2 SH2;
Src SH2
-
0.07
--

Substrate: c-kit (Receptor tyrosine kinase)
Seq-ID: P10721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 703 KQEDHAEAALYKNLLHSKESS Kit 10377264
LTP
1.00
GRB2 SH2 TyrKc
0.30
--
Y 936 KQISESTNHIYSNLANCSPNR Kit 10377264
LTP
1.00
GRB2 SH2;
GRB7 SH2;
PLCG1 SH2
-
0.38
--
Y 936 KQISESTNHIYSNLANCSPNR - 18083107
HTP
1.00
GRB2 SH2;
GRB7 SH2;
PLCG1 SH2
-
0.38
--

Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)
Seq-ID: O43561 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 220 AEASLDGSREYVNVSQELHPG - 15659558
HTP
1.00
GRAP2 SH2;
GRB2 SH2;
PIK3R1 SH2;
PLCG1 SH2;
VAV1 SH2
-
0.71
- medium

Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)
Seq-ID: O54957 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 175 SAFSVESCEDYVNVPESEESA - 10811803
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.71
- low
Y 175 SAFSVESCEDYVNVPESEESA ZAP70 11368773
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.71
- low
Y 195 AEASLDGSREYVNVSPEQQPV - 10811803
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.83
- low
Y 195 AEASLDGSREYVNVSPEQQPV ZAP70 11368773
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.83
- low
Y 235 EGVDGEEAPDYENLQELN    - 10811803
LTP
1.00
GRB2 SH2;
VAV_group SH2
-
0.90
- low
Y 235 EGVDGEEAPDYENLQELN    ZAP70 11368773
LTP
1.00
GRB2 SH2;
VAV_group SH2
-
0.90
- low

Substrate: FAK (Focal adhesion kinase)
Seq-ID: Q05397 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 397 HAVSVSETDDYAEIIDEEDTY FAK 7509446
LTP
1.00
Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2
-
0.49
--
Y 397 HAVSVSETDDYAEIIDEEDTY - 17192257
HTP
1.00
Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2
-
0.49
--
Y 397 HAVSVSETDDYAEIIDEEDTY - 18083107
HTP
1.00
Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2
-
0.49
--
Y 925 ANLDRSNDKVYENVTGLVKAV - 12370821
LTP
1.00
GRB2 SH2;
STAT3 SH2
Focal_AT
0.45
1K04 39.30%
Y 925 ANLDRSNDKVYENVTGLVKAV - 7997267
LTP
1.00
GRB2 SH2;
STAT3 SH2
Focal_AT
0.45
1K04 39.30%

Substrate: Insulin receptor substrate 2 (Adaptor molecule)
Seq-ID: Q9Y4H2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 919 LPPEPKSPGEYINIDFGEPGA - 18669648
HTP
1.00
GRB2 SH2 -
0.77
- medium

Substrate: CBL E3 ubiquitin protein ligase (Adaptor molecule)
Seq-ID: P22681 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 552 LPPPPPPDRPYSVGAESRPQR - 15951569
HTP
0.04
Fyn SH2;
GRB2 SH2
-
0.94
--

Substrate: P130Cas (Adaptor molecule. Contain 15 YxxP motifs. )
Seq-ID: P56945 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 653 FTSQDSPDGQYENSEGGWMED SRC 11604500
LTP
1.00
GRB2 SH2;
Src SH2
-
0.75
- medium
Y 653 FTSQDSPDGQYENSEGGWMED - 8670206
LTP
1.00
GRB2 SH2;
Src SH2
-
0.75
- medium
Y 653 FTSQDSPDGQYENSEGGWMED - 12480533
LTP
1.00
GRB2 SH2;
Src SH2
-
0.75
- medium

Substrate: ErbB4 (protein binding, protein heterodimerization activity)
Seq-ID: Q15303 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1188 GDLQALDNPEYHNASNGPPKA - 8617750
LTP
0.10
GRB2 SH2 -
0.83
--
Y 1242 KAKKAFDNPDYWNHSLPPRST - 8617750
LTP
1.00
GRB2 SH2 -
0.57
--

Substrate: EGFR (Receptor for EGF and other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor,)
Seq-ID: P00533 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1092 IDDTFLPVPEYINQSVPKRPA EGFR 8845374
LTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1092 IDDTFLPVPEYINQSVPKRPA - 15302935
HTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1092 IDDTFLPVPEYINQSVPKRPA - 17081983
HTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1092 IDDTFLPVPEYINQSVPKRPA - 18083107
HTP
0.05
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
STAT3 SH2
-
0.57
--
Y 1110 RPAGSVQNPVYHNQPLNPAPS EGFR 8845374
LTP
1.00
GRB2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 PTB;
Src SH2;
STAT3 SH2
-
0.80
--
Y 1110 RPAGSVQNPVYHNQPLNPAPS - 15302935
HTP
1.00
GRB2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 PTB;
Src SH2;
STAT3 SH2
-
0.80
--
Y 1172 SHQISLDNPDYQQDFFPKEAK EGFR 8845374
LTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1172 SHQISLDNPDYQQDFFPKEAK - 15302935
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1172 SHQISLDNPDYQQDFFPKEAK - 17081983
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1172 SHQISLDNPDYQQDFFPKEAK - 18083107
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 PTB;
SHC3 PTB;
Src SH2;
VAV2 SH2
-
0.67
--
Y 1197 FKGSTAENAEYLRVAPQSSEF EGFR 8845374
LTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 SH2;
SHC3 SH2;
Src SH2
-
0.54
--
Y 1197 FKGSTAENAEYLRVAPQSSEF - 15302935
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 SH2;
SHC3 SH2;
Src SH2
-
0.54
--
Y 1197 FKGSTAENAEYLRVAPQSSEF - 17081983
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 SH2;
SHC3 SH2;
Src SH2
-
0.54
--
Y 1197 FKGSTAENAEYLRVAPQSSEF - 18083107
HTP
1.00
ABL1 SH2;
GRB2 SH2;
PLCG1 SH2;
PTPN6 SH2;
RASA_group SH2;
SHC1 SH2;
SHC3 SH2;
Src SH2
-
0.54
--

Substrate: Shc ( Adaptor molecule)
Seq-ID: P29353 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 349 EEEEEPPDHQYYNDFPGKEPP - 11075717
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 9121430
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP SYK 9710204
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP ZAP70 9710204
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 10891441
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 11687594
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 15592455
HTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP FLT4 9927207
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 350 EEEEPPDHQYYNDFPGKEPPL - 11075717
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 350 EEEEPPDHQYYNDFPGKEPPL - 9121430
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 350 EEEEPPDHQYYNDFPGKEPPL SYK 9710204
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 350 EEEEPPDHQYYNDFPGKEPPL ZAP70 9710204
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 350 EEEEPPDHQYYNDFPGKEPPL - 15592455
HTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 350 EEEEPPDHQYYNDFPGKEPPL FLT4 9927207
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 11075717
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR SYK 9710204
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR ZAP70 9710204
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 8610109
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 9741627
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 12522270
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 15592455
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR FLT4 9927207
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 18083107
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 18669648
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--

Substrate: RET (Probable receptor with tyrosine-protein kinase activity; important for development.)
Seq-ID: P07949 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1090 ADGTNTGFPRYPNDSVYANWM RET 14711813
LTP
0.16
GRB2 SH2 -
0.41
--
Y 1096 GFPRYPNDSVYANWMLSPSAA - 11470823
LTP
1.00
GRB2 SH2 -
0.33
--
Y 1096 GFPRYPNDSVYANWMLSPSAA RET 8621380
LTP
1.00
GRB2 SH2 -
0.33
--
Y 1096 GFPRYPNDSVYANWMLSPSAA RET 14711813
LTP
1.00
GRB2 SH2 -
0.33
--

Substrate: CD136 (Receptor tyrosine kinase)
Seq-ID: Q04912 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1353 QIVSALLGDHYVQLPATYMNL RON 10871856
LTP
1.00
GRB2 SH2;
PIK3R1 SH2;
PLCG1 SH2;
SHC1 SH2
-
0.21
- low
Y 1360 GDHYVQLPATYMNLGPSTSHE RON 10871856
LTP
1.00
GRB2 SH2;
PIK3R1 SH2;
PLCG1 SH2;
SHC1 SH2
-
0.40
- low

Substrate: PYK2 (Focal adhesion kinase 2)
Seq-ID: Q14289 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 881 ANLDRTDDLVYLNVMELVRAV - 10880513
LTP
1.00
GRB2 SH2;
PTPN11 SH2
Focal_AT
0.23
3GM1 24.02%

Substrate: PDGF-R beta (Beta platelet-derived growth factor receptor)
Seq-ID: P09619 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 716 DKRRPPSAELYSNALPVGLPL PDGFR_beta 8940081
LTP
1.00
GRB2 SH2;
GRB7 SH2
TyrKc
0.46
- medium
Y 716 DKRRPPSAELYSNALPVGLPL PDGFR_beta 7935391
LTP
1.00
GRB2 SH2;
GRB7 SH2
TyrKc
0.46
- medium
Y 775 DIESSNYMAPYDNYVPSAPER PDGFR_beta 8940081
LTP
1.00
GRB2 SH2;
GRB7 SH2;
STAT5 SH2
TyrKc
0.34
- medium

Substrate: LAT2 (protein binding, SH2 domain binding)
Seq-ID: Q9GZY6 [Homo sapiens]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 136 KPPEDDDANSYENVLICKQKT - 14722116
LTP
1.00
GRB2 SH2 -
0.63
- medium
Y 193 SPEEDEESEDYQNSASIHQWR - 14722116
LTP
1.00
GRB2 SH2 -
0.84
- medium
Y 233 SPDEEDGEPDYVNGEVAATEA - 14722116
LTP
1.00
GRB2 SH2 -
0.90
- medium

Substrate: c-met (Receptor tyrosine kinase for hepatocyte growth factor.)
Seq-ID: P08581 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 12475979
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9444958
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9252406
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 7513258
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7731718
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7687741
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9826708
LTP
1.00
GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.03
3F66 100.00%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 12475979
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 9444958
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 9252406
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 7513258
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7731718
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 8662889
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7961992
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7687741
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 9826708
LTP
1.00
GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2
-
0.06
1R0P 15.72%

Substrate: TIE2 (TEK) (PTK receptor for angiopoietin 1)
Seq-ID: Q02763 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1102 LNRMLEERKTYVNTTLYEKFT - 10521483
LTP
1.00
GRB2 SH2;
GRB7 SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2
-
0.15
1FVR 3.49%
Y 1102 LNRMLEERKTYVNTTLYEKFT - 9632797
LTP
1.00
GRB2 SH2;
GRB7 SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2
-
0.15
1FVR 3.49%
Y 1102 LNRMLEERKTYVNTTLYEKFT TIE2 12082108
LTP
1.00
GRB2 SH2;
GRB7 SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2
-
0.15
1FVR 3.49%

Substrate: CD28 (Involved in T cell activation)
Seq-ID: P10747 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 191 SKRSRLLHSDYMNMTPRRPGP Lck 8992971
LTP
0.95
GRAP2 SH2;
GRB2 SH2;
ITK SH2;
PIK3R1 SH2
-
0.44
- medium
Y 191 SKRSRLLHSDYMNMTPRRPGP ITK 8992971
LTP
0.95
GRAP2 SH2;
GRB2 SH2;
ITK SH2;
PIK3R1 SH2
-
0.44
- medium
Y 191 SKRSRLLHSDYMNMTPRRPGP - 16094384
HTP
0.95
GRAP2 SH2;
GRB2 SH2;
ITK SH2;
PIK3R1 SH2
-
0.44
- medium

Substrate: VEGFR-1 (Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity.)
Seq-ID: P17948 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1213 FNSGSSDDVRYVNAFKFMSLE FLT1 11513746
LTP
1.00
GRB2 SH2;
NCK SH2;
PIK3R1 SH2;
PTPN11 SH2
-
0.20
- low
Y 1213 FNSGSSDDVRYVNAFKFMSLE FLT1 9722576
LTP
1.00
GRB2 SH2;
NCK SH2;
PIK3R1 SH2;
PTPN11 SH2
-
0.20
- low
Y 1213 FNSGSSDDVRYVNAFKFMSLE - 9600074
LTP
1.00
GRB2 SH2;
NCK SH2;
PIK3R1 SH2;
PTPN11 SH2
-
0.20
- low

Substrate: SIT Protein (Adapter molecule)
Seq-ID: Q9Y3P8 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 90 SGESVEEVPLYGNLHYLQTGR - 11433379
LTP
- GRB2 SH2 -
0.39
- medium
Y 90 SGESVEEVPLYGNLHYLQTGR - 15144186
HTP
- GRB2 SH2 -
0.39
- medium
Y 90 SGESVEEVPLYGNLHYLQTGR - 15592455
HTP
- GRB2 SH2 -
0.39
- medium
Y 188 RARASFPDQAYANSQPAAS   - 10209036
LTP
- GRB2 SH2 -
0.71
- medium
Y 188 RARASFPDQAYANSQPAAS   - 15144186
HTP
- GRB2 SH2 -
0.71
- medium
Y 188 RARASFPDQAYANSQPAAS   - 15592455
HTP
- GRB2 SH2 -
0.71
- medium

Substrate: DOK3 (Docking proteins interact with receptor tyrosine kinases)
Seq-ID: Q7L591 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin receptor binding plasma membrane,
cytoplasm
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 432 GSRSPTTSPIYHNGQDLSWPG - 16497976
HTP
1.00
GRB2 SH2 -
0.81
- medium

Substrate: Amyloid beta A4 protein (Cell surface receptor)
Seq-ID: P05067 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 757 RHLSKMQQNGYENPTYKFFEQ - 11279131
LTP
1.00
ABL1 SH2;
GRB2 SH2;
SHC1 SH2
APP_amyloid
0.38
--
Y 757 RHLSKMQQNGYENPTYKFFEQ - 18083107
HTP
1.00
ABL1 SH2;
GRB2 SH2;
SHC1 SH2
APP_amyloid
0.38
--

Substrate: Beta-2 adrenergic receptor (Protein G coupled receptor)
Seq-ID: P04274 [Mesocricetus auratus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 350 LCLRRSSSKAYGNGYSSNSNG - 8521811
LTP
0.10
GRB2 SH2 -
0.30
- medium
Y 350 LCLRRSSSKAYGNGYSSNSNG INSR 8557631
LTP
0.10
GRB2 SH2 -
0.30
- medium

Substrate: TRKA (Required for high affinity binding to nerve growth factor , neurotrophin-3 and neurotrophin-4/5r.)
Seq-ID: P04629 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 496 LQGHIIENPQYFSDACVHHIK TRKA 11159935
LTP
1.00
FRS2 PTB;
GRB2 SH2;
PLCG1 SH2;
SHC1 PTB;
SHC1 SH2
-
0.16
- medium
Y 496 LQGHIIENPQYFSDACVHHIK TRKA 8155326
LTP
1.00
FRS2 PTB;
GRB2 SH2;
PLCG1 SH2;
SHC1 PTB;
SHC1 SH2
-
0.16
- medium

Substrate: Insulin R (Receptor tyrosine kinase)
Seq-ID: P06213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 992 RQPDGPLGPLYASSNPEYLSA INSR 1658004
LTP
1.00
GRB2 SH2 -
0.33
--
Y 1011 SASDVFPCSVYVPDEWEVSRE INSR 12707268
LTP
0.06
GRB2 SH2 -
0.11
1IR3 77.98%

Substrate: CD19 (Antigen of human B-lymphocytes)
Seq-ID: P15391 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 348 PPPGSGPQNQYGNVLSLPTPT - 10706702
LTP
1.00
GRB2 SH2 -
0.78
- medium
Y 378 AAGLGGTAPSYGNPSSDVQAD - 10706702
LTP
1.00
GRB2 SH2;
VAV_group SH2
-
0.71
- medium

Substrate: ErbB2 (Receptor tyrosine kinase)
Seq-ID: P04626 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1139 APLTCSPQPEYVNQPDVRPQP ErbB2 11500516
LTP
1.00
GRB2 SH2;
GRB7 SH2;
Src SH2;
STAT3 SH2
-
0.85
- low
Y 1221 PAFSPAFDNLYYWDQDPPERG ErbB2 11500516
LTP
0.19
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.67
- low


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