Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

14-3-3 zeta/delta
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
AKT1S1
Androgen receptor
Ataxin 1
B-Raf
BAD
BAX
Beta-2 adrenergic receptor
BIRC4
BRCA1
cAMP-dependent protein kinase type II-beta regulatory subunit
Caspase 9
CD136
CENTB1
CHK1
Cyclin dependent kinase inhibitor 1B
Desmoyokin
E1A-associated protein p300
FANCA
Forkhead box protein O1A
Forkhead box protein O3A
Forkhead box protein O4
Gab2
GATA1
Grb10
GSK-3 alpha
Huntingtin
IKK-alpha
Insulin receptor substrate 1
IRAK1
MAP2K4
MAP3K11
MAP3K5
MAP3K8
Mdm2
mTOR
Neutrophil cytosol factor 1
Nitric-oxide synthase, endothelial
NUAK1
Orphan nuclear receptor NR4A1
p21
p21-Rac1
PDCD4
PEA15
Phosphodiesterase 3B
PIP5K
Raf1
S1P receptor EDG1
Serine/threonine-protein kinase WNK1
TBC1D4
Telomerase reverse transcriptase
Tuberin
Tyrosine-protein phosphatase, non-receptor type 1
YAP65
ZFP36L1

Substrate:

14-3-3 zeta/delta (14-3-3 protein zeta/delta (Protein kinase C inhibitor protein-1) (KCIP-1) (Factor activating exoenzyme S) (FAS))

Seq-ID:

P63104 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14323   FOXO3_HUMAN
MINT-14772   PRLR_HUMAN
MINT-17015   IL9R_HUMAN
MINT-17278   KC1A_HUMAN
MINT-17367   TPD53_HUMAN
MINT-17571   RIN1_HUMAN
MINT-17818   ATX1_HUMAN
MINT-19329   MPIP2_HUMAN
MINT-19336   ADA23_HUMAN
MINT-45800   RAF1_HUMAN
MINT-48206   NEMO_HUMAN
MINT-48480   M3K3_HUMAN
MINT-50358   HSP71_HUMAN
MINT-50935   EGFR_HUMAN
MINT-51005   IF4A3_HUMAN
MINT-51010   TRA2B_HUMAN
MINT-51012   DFFA_HUMAN
MINT-51013   STK38_HUMAN
MINT-51018   E41L3_HUMAN
MINT-51019   MEP50_HUMAN
MINT-51020   RO52_HUMAN
MINT-51021   TBB5_HUMAN
MINT-51022   ZO2_HUMAN
MINT-51025   KLC4_HUMAN
MINT-51027   Q8IXP7_HUMAN
MINT-51051   K1C19_HUMAN
MINT-51052   K1C18_HUMAN
MINT-63980   KU70_HUMAN
MINT-74924   KAPCA_HUMAN
MINT-74925   P53_HUMAN
MINT-3294407   MPIP1_HUMAN
MINT-3294433   MPIP3_HUMAN
MINT-3294883   MARK2_HUMAN
MINT-3295089   NUMA1_HUMAN
MINT-3295217   PCM1_HUMAN
MINT-3295255   NDE1_HUMAN
MINT-3295375   WEE1_HUMAN
MINT-3295392   CDK18_HUMAN
MINT-3295415   CDK17_HUMAN
MINT-3295530   MARK3_HUMAN
MINT-3295552   BRAF_HUMAN
MINT-3295573   MPRIP_HUMAN
MINT-3295597   ARHG2_HUMAN
MINT-3295618   RHG21_HUMAN
MINT-3295674   GAPD1_HUMAN
MINT-3295696   ARHGG_HUMAN
MINT-3295740   ATLA2_HUMAN
MINT-3295774   LIPB1_HUMAN
MINT-3295882   IRS2_HUMAN
MINT-3295899   PDE3A_HUMAN
MINT-3295953   LIMA1_HUMAN
MINT-3295975   CALM_HUMAN
MINT-3295996   PARD3_HUMAN
MINT-3296030   SI1L3_HUMAN
MINT-3296068   APC_HUMAN
MINT-3296095   NOLC1_HUMAN
MINT-3296132   NUCL_HUMAN
MINT-3296152   NPM_HUMAN
MINT-3296187   PSMD2_HUMAN
MINT-3296221   THIO_HUMAN
MINT-3296237   PRDX1_HUMAN
MINT-3296270   CE170_HUMAN
MINT-3296359   PYRG1_HUMAN
MINT-3296408   NADK_HUMAN
MINT-3296440   NDKB_HUMAN
MINT-3296457   KITH_HUMAN
MINT-3296491   HDAC4_HUMAN
MINT-3296507   HDAC7_HUMAN
MINT-3296523   YBOX1_HUMAN
MINT-3296639   HAT1_HUMAN
MINT-3296655   H4_HUMAN
MINT-3296701   H2A1_HUMAN
MINT-3296729   SPT6H_HUMAN
MINT-3296749   DNMT1_HUMAN
MINT-3296781   RUVB2_HUMAN
MINT-3296831   HNRPF_HUMAN
MINT-3296856   HNRH2_HUMAN
MINT-3296872   HNRPK_HUMAN
MINT-3296888   PCBP1_HUMAN
MINT-3296904   HNRPC_HUMAN
MINT-3296922   ROA1_HUMAN
MINT-3296956   DDX1_HUMAN
MINT-3296972   DDX3X_HUMAN
MINT-3297068   LA_HUMAN
MINT-3297088   RS3_HUMAN
MINT-3297112   RLA0_HUMAN
MINT-3297147   RL19_HUMAN
MINT-3297169   RL5_HUMAN
MINT-3297185   RLA2_HUMAN
MINT-3297202   RS7_HUMAN
MINT-3297276   SYEP_HUMAN
MINT-3297301   PABP2_HUMAN
MINT-3297322   PABP4_HUMAN
MINT-3297360   GCN1L_HUMAN
MINT-3297377   IF4G1_HUMAN
MINT-3297431   EIF3F_HUMAN
MINT-3297456   EF2_HUMAN
MINT-3297472   EF1A1_HUMAN
MINT-3297494   EF1B_HUMAN
MINT-3297642   KINH_HUMAN
MINT-3297660   KLC2_HUMAN
MINT-3297714   DYHC1_HUMAN
MINT-3297730   TBA1B_HUMAN
MINT-3297793   VIME_HUMAN
MINT-3297814   LMNA_HUMAN
MINT-3297843   LMNB1_HUMAN
MINT-3297866   ANXA2_HUMAN
MINT-3297886   ANXA1_HUMAN
MINT-3297917   ACTB_HUMAN
MINT-3297984   TLN1_HUMAN
MINT-3298006   FSCN1_HUMAN
MINT-3298028   HAKAI_HUMAN
MINT-3298189   PROF1_HUMAN
MINT-3298215   COF1_HUMAN
MINT-3304213   K6PP_HUMAN
MINT-3304235   F262_HUMAN
MINT-3304340   FAS_HUMAN
MINT-3304385   ACSL4_HUMAN
MINT-3304469   G3P_HUMAN
MINT-3304487   KCRU_HUMAN
MINT-3304522   LDHB_HUMAN
MINT-3304540   LDHA_HUMAN
MINT-3304560   SPRE_HUMAN
MINT-3304637   KPYM_HUMAN
MINT-3304676   TKT_HUMAN
MINT-3304695   ALDOA_HUMAN
MINT-3304712   ENOA_HUMAN
MINT-3304765   TPIS_HUMAN
MINT-3304790   TCPQ_HUMAN
MINT-3304899   TCPA_HUMAN
MINT-3305086   CH60_HUMAN
MINT-3305120   GRP78_HUMAN
MINT-3305183   HS90A_HUMAN
MINT-3305276   HS105_HUMAN
MINT-3305331   HSPB1_HUMAN
MINT-3305423   PPIA_HUMAN
MINT-3305616   TRAP1_HUMAN
MINT-3305679   HS71L_HUMAN
MINT-3305799   IPO7_HUMAN
MINT-3305862   IMB1_HUMAN
MINT-3306240   TIF1B_HUMAN
MINT-3306314   CIC_HUMAN
MINT-3306548   LMO7_HUMAN
MINT-3306606   VIR_HUMAN
MINT-3306625   FL2D_HUMAN
MINT-3306813   ZC3HD_HUMAN
MINT-3307270   PERQ2_HUMAN
MINT-3307331   LARP1_HUMAN
MINT-3307383   FNBP2_HUMAN
MINT-3307403   SMAG2_HUMAN
MINT-3307456   TERA_HUMAN
MINT-3307546   TPD52_HUMAN
MINT-3307735   MYCB2_HUMAN
MINT-3307756   MCM3_HUMAN
MINT-3307783   ASPP2_HUMAN
MINT-3307813   P3C2B_HUMAN
MINT-3307838   FRAP_HUMAN
MINT-3308034   PAK4_HUMAN
MINT-3308059   RPGF2_HUMAN
MINT-3308248   IQGA1_HUMAN
MINT-3308267   RPGP1_HUMAN
MINT-3308328   ATLA3_HUMAN
MINT-3308436   SRGP1_HUMAN
MINT-3308521   AFAD_HUMAN
MINT-3308685   LIPB1_HUMAN
MINT-3317863   TSC2_HUMAN
MINT-3317888   AKTS1_HUMAN
MINT-3317913   PTN3_HUMAN
MINT-3317930   YAP1_HUMAN
MINT-3317972   SH3B4_HUMAN
MINT-3317988   PSMD1_HUMAN
MINT-3318133   UBP8_HUMAN
MINT-3318149   CAND1_HUMAN
MINT-3318217   UBA1_HUMAN
MINT-3318321   PYR1_HUMAN
MINT-3318337   HDAC5_HUMAN
MINT-3318368   PRI2_HUMAN
MINT-3318428   PTBP1_HUMAN
MINT-3318458   HNRPU_HUMAN
MINT-3318488   DCP1A_HUMAN
MINT-3318520   DHX9_HUMAN
MINT-3318572   SRRM2_HUMAN
MINT-3318588   SYVC_HUMAN
MINT-3318610   SYIC_HUMAN
MINT-3318644   SYAC_HUMAN
MINT-3318676   EIF3A_HUMAN
MINT-3318692   IF4A1_HUMAN
MINT-3318708   KIF23_HUMAN
MINT-3318724   KLC3_HUMAN
MINT-3318808   FLNA_HUMAN
MINT-3318838   CING_HUMAN
MINT-3318854   AHNK_HUMAN
MINT-3318871   DESP_HUMAN
MINT-3318887   EZRI_HUMAN
MINT-3318904   SPTA2_HUMAN
MINT-3318920   SPTB2_HUMAN
MINT-3318937   VINC_HUMAN
MINT-3318960   ACTN4_HUMAN
MINT-3318976   PGAM1_HUMAN
MINT-3319004   PGK1_HUMAN
MINT-3319021   S27A2_HUMAN
MINT-3319127   PANK2_HUMAN
MINT-3319198   PURA1_HUMAN
MINT-3319239   CGL_HUMAN
MINT-3319281   TFR1_HUMAN
MINT-3319320   GRP75_HUMAN
MINT-3319337   HSP7C_HUMAN
MINT-3319393   FKBP4_HUMAN
MINT-3319394   HSP74_HUMAN
MINT-3319575   HS90B_HUMAN
MINT-3319592   XPO1_HUMAN
MINT-3319626   NFAC1_HUMAN
MINT-3319708   NUFP1_HUMAN
MINT-3319791   SET_HUMAN
MINT-3319822   CV028_HUMAN
MINT-3319865   TBCD4_HUMAN
MINT-3319899   KIBRA_HUMAN
MINT-3319917   RAI14_HUMAN
MINT-3319945   MVP_HUMAN
MINT-3319979   1433S_HUMAN
MINT-3319998   ESYT1_HUMAN
MINT-3320046   EDC3_HUMAN
MINT-3320063   MYCPP_HUMAN
MINT-3320079   CLH1_HUMAN
MINT-3320095   MYOF_HUMAN
MINT-3320159   SCAM2_HUMAN
MINT-7262288   KPCE_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein domain specific binding, transcription factor binding	melanosome	anti-apoptosis, signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	58	YKNVVGARRSSWRVVSSIEQK	PKB_group	11956222	LTP	-	MOD_PKA_1	-	14_3_3	0.30	2O02	45.90%

Substrate:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Enzyme: Phosphotransferase)

Seq-ID:

O60825 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3304235 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
6-phosphofructo-2-kinase activity, fructose-2,6-bisphosphate 2-phosphatase activity, ATP binding	cytosol	fructose 2,6-bisphosphate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	466	NQTPVRMRRNSFTPLSSSNTI	PKB_group	12853467	LTP	0.58	MOD_PKB_1	-	-	0.63	-	low
S	483	SNTIRRPRNYSVGSRPLKPLS	PKB_group	12853467	LTP	0.76	MOD_PKB_1	-	-	0.57	-	low

Substrate:

AKT1S1 (Unclassified)

Seq-ID:

Q96B36 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3317888 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cytosolic part	negative regulation of TOR signaling cascade, neuroprotection, negative regulation of cell size, regulation of survival gene product expression, negative regulation of protein kinase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	246	FGDLPRPRLNTSDFQKLKRKY	PKB_group	12524439	LTP	1.00	MOD_PKB_1	-	-	0.56	-	low
T	246	FGDLPRPRLNTSDFQKLKRKY	PKB_group	17277771	LTP	1.00	MOD_PKB_1	-	-	0.56	-	low

Substrate:

Androgen receptor (Androgen receptor (Dihydrotestosterone receptor))

Seq-ID:

P10275 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16136   KAT5_HUMAN
MINT-16359   FHL2_HUMAN
MINT-16600   MYST2_HUMAN
MINT-49803   CTNB1_HUMAN
MINT-49804   NCOA2_HUMAN
MINT-1781599   IF16_HUMAN
MINT-4051509   CASP8_HUMAN
MINT-4051926   CASP8_MOUSE
MINT-4298190   SMAD1_HUMAN
MINT-5207365   ETS1_HUMAN
MINT-7103733   P53_HUMAN
MINT-7103819   NSD2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein dimerization activity, androgen receptor activity, transcription activator activity, androgen binding, beta-catenin binding, transcription factor binding, zinc ion binding, promoter binding, receptor binding, sequence-specific DNA binding transcription factor activity	cytoplasm, nucleus	positive regulation of gene-specific transcription from RNA polymerase II promoter, cell growth, cell-cell signaling, transport, transcription, DNA-dependent, cell proliferation, cell death

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	213	GSSSGRAREASGAPTSSKDNY	PKB_group	11404460	LTP	-	MOD_PKB_1	-	Androgen_recep	0.78	-	-
S	791	YSQCVRMRHLSQEFGWLQITP	PKB_group	11404460	LTP	1.00	MOD_PKB_1	-	HOLI	0.05	2AX6	0.00%
S	791	YSQCVRMRHLSQEFGWLQITP	PKB_group	11156376	LTP	1.00	MOD_PKB_1	-	HOLI	0.05	2AX6	0.00%

Substrate:

Ataxin 1 (RNA binding protein)

Seq-ID:

P54253 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-17818   1433Z_HUMAN
MINT-2855089   CCNK_HUMAN
MINT-2855127   CRK_HUMAN
MINT-2855165   CPSF7_HUMAN
MINT-2855184   IST1_HUMAN
MINT-2855315   TBCD5_HUMAN
MINT-2855353   TRI32_HUMAN
MINT-2855372   U2AF2_HUMAN
MINT-2855860   COF1_HUMAN
MINT-2855879   ZEP1_HUMAN
MINT-2855926   ZHX1_HUMAN
MINT-2855945   ATX2_HUMAN
MINT-2856362   BAT2_HUMAN
MINT-2856791   ADCY6_HUMAN
MINT-2856943   APBB1_HUMAN
MINT-2857450   CDK6_HUMAN
MINT-2857675   CIRBP_HUMAN
MINT-2858986   FHL2_HUMAN
MINT-2859062   FYN_HUMAN
MINT-2859701   NR4A1_HUMAN
MINT-2859843   HSP71_HUMAN
MINT-2860098   ITB4_HUMAN
MINT-2860762   MBP_HUMAN
MINT-2861028   SYNC_HUMAN
MINT-2861702   PEPD_HUMAN
MINT-2862865   CIC_HUMAN
MINT-2863265   Q59G16_HUMAN
MINT-2863379   SRBP1_HUMAN
MINT-2863486   GCF_HUMAN
MINT-2863813   TRIP6_HUMAN
MINT-2864284   ZYX_HUMAN
MINT-2864784   COIL_HUMAN
MINT-2865350   KCAB2_HUMAN
MINT-2865388   TELT_HUMAN
MINT-2865772   DNJA3_HUMAN
MINT-2866257   NUMBL_HUMAN
MINT-2867106   NCOR1_HUMAN
MINT-2867216   PUM1_HUMAN
MINT-2867264   SAPS2_HUMAN
MINT-2867463   MLL4_HUMAN
MINT-2867712   TOX4_HUMAN
MINT-2867796   UBP2L_HUMAN
MINT-2868027   SFR14_HUMAN
MINT-2868342   UB2E3_HUMAN
MINT-2868490   IPO8_HUMAN
MINT-2869125   PIM2_HUMAN
MINT-2869398   SFR16_HUMAN
MINT-2869696   ATX2L_HUMAN
MINT-2869911   R3HD2_HUMAN
MINT-2870228   ZHX3_HUMAN
MINT-2870293   K0913_HUMAN
MINT-2870343   ZN609_HUMAN
MINT-2870505   GPTC8_HUMAN
MINT-2870822   Z3H7B_HUMAN
MINT-2871037   R3HD1_HUMAN
MINT-2872173   AHDC1_HUMAN
MINT-2872266   SETD2_HUMAN
MINT-2873442   MED15_HUMAN
MINT-2873882   QRIC1_HUMAN
MINT-2877796   UNK_HUMAN
MINT-2877872   LRSM1_HUMAN
MINT-2877949   ZN276_HUMAN
MINT-2879283   FA21C_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, protein C-terminus binding, identical protein binding, protein self-association, poly(U) RNA binding, poly(G) RNA binding	cytoplasm, nuclear matrix, nucleoplasm, nuclear inclusion body	RNA processing, nuclear export, cell death

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	776	KPAATRKRRWSAPESRKLEKS	PKB_group	12757707	LTP	0.85	MOD_PKB_1	-	-	0.77	-	medium

Substrate:

B-Raf (B-Raf proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P15056 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50344   1433B_HUMAN
MINT-50372   1433T_HUMAN
MINT-2833162   KPCA_HUMAN
MINT-2833238   KPCE_HUMAN
MINT-2833314   KS6A2_HUMAN
MINT-3295552   1433Z_HUMAN
MINT-3374124   M3K1_HUMAN
MINT-3975375   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, ATP binding	cytoplasm, nucleus	protein amino acid phosphorylation, organ morphogenesis, anti-apoptosis, small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	365	NQFGQRDRSSSAPNVHINTIE	PKB_group	10869359	LTP	1.00	MOD_PKB_1	YWHAB 14-3-3	-	0.74	-	-
S	365	NQFGQRDRSSSAPNVHINTIE	PKB_group	11410590	LTP	1.00	MOD_PKB_1	YWHAB 14-3-3	-	0.74	-	-
S	429	SPGPQRERKSSSSSEDRNRMK	PKB_group	10869359	LTP	1.00	MOD_PKA_1	-	-	0.92	-	-

Substrate:

BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))

Seq-ID:

Q61337 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytosol, mitochondrial outer membrane	induction of apoptosis by extracellular signals, glucose homeostasis, cytokine-mediated signaling pathway, apoptosis, positive regulation of B cell differentiation, positive regulation of T cell differentiation, glucose catabolic process, cell proliferation, regulation of caspase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	112	GAMETRSRHSSYPAGTEEDEG	PKB_group	9381178	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	Bcl-2_BAD	0.88	-	medium
S	112	GAMETRSRHSSYPAGTEEDEG	PKB_group	10949026	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	Bcl-2_BAD	0.88	-	medium
S	112	GAMETRSRHSSYPAGTEEDEG	PKB_group	11983683	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	Bcl-2_BAD	0.88	-	medium
S	136	ELSPFRGRSRSAPPNLWAAQR	PKB_group	9381178	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	Bcl-2_BAD	0.66	-	medium
S	136	ELSPFRGRSRSAPPNLWAAQR	PKB_group	10949026	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	Bcl-2_BAD	0.66	-	medium

Substrate:

BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))

Seq-ID:

Q92934 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14699   B2CL1_HUMAN
MINT-66103   1433S_HUMAN
MINT-7034091   B2L11_HUMAN
MINT-7717137   NAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding	cytosol, mitochondrial outer membrane	induction of apoptosis by extracellular signals, activation of pro-apoptotic gene products

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	99	EPSPFRGRSRSAPPNLWAAQR	PKB_group	11020382	LTP	1.00	MOD_PKB_1	-	Bcl-2_BAD	0.76	-	medium

Substrate:

BAX (protein binding)

Seq-ID:

Q07813 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-13682 VDAC1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein heterodimerization activity, protein homodimerization activity, BH3 domain binding	integral to membrane, soluble fraction, endoplasmic reticulum, cytosolic part, mitochondrial outer membrane	positive regulation of apoptosis involved in mammary gland involution, negative regulation of fibroblast proliferation, response to salt stress, positive regulation of neuron apoptosis, positive regulation of release of sequestered calcium ion into cytosol, response to toxin, blood vessel remodeling, positive regulation of B cell apoptosis, fertilization, kidney development, nuclear fragmentation involved in apoptotic nuclear change, hypothalamus development, B cell homeostasis, negative regulation of peptidyl-serine phosphorylation, negative regulation of anti-apoptosis, myeloid cell homeostasis, odontogenesis of dentine-containing tooth, development of secondary sexual characteristics, protein homooligomerization, glycosphingolipid metabolic process, B cell homeostatic proliferation, mitochondrial fusion, B cell apoptosis, retinal cell programmed cell death, protein insertion into mitochondrial membrane involved in induction of apoptosis, cellular response to UV, homeostasis of number of cells within a tissue, positive regulation of developmental pigmentation, regulation of cell cycle, reduction of endoplasmic reticulum calcium ion concentration, regulation of mammary gland epithelial cell proliferation, germ cell programmed cell death, activation of caspase activity by cytochrome c, release of cytochrome c from mitochondria, germ cell development, response to axon injury, spermatid differentiation, B cell negative selection, induction of apoptosis in response to chemical stimulus, regulation of mitochondrial membrane permeability, response to gamma radiation, vagina development, neuron migration, retina development in camera-type eye, induction of apoptosis by intracellular signals, apoptosis in response to endoplasmic reticulum stress, neuron apoptosis, post-embryonic camera-type eye morphogenesis, negative regulation of neuron apoptosis, Sertoli cell proliferation, T cell homeostatic proliferation, response to DNA damage stimulus, regulation of nitrogen utilization, limb morphogenesis, cerebral cortex development, ovarian follicle development, response to acid

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	184	TIFVAGVLTASLTIWKKMG	PKB_group	14766748	LTP	0.04		-	TRANS	0.01	-	low

Substrate:

Beta-2 adrenergic receptor (Protein G coupled receptor)

Seq-ID:

P07550 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1796656   NHRF1_HUMAN
MINT-4051815   SRC_HUMAN
MINT-7291631   UBP33_HUMAN
MINT-7720120   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
potassium channel regulator activity, protein homodimerization activity, norepinephrine binding, beta2-adrenergic receptor activity	receptor complex, endosome, integral to plasma membrane, lysosome	positive regulation of MAPKKK cascade, receptor-mediated endocytosis, activation of transmembrane receptor protein tyrosine kinase activity, endosome to lysosome transport, desensitization of G-protein coupled receptor protein signaling pathway by arrestin

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	346	FQELLCLRRSSLKAYGNGYSS	PKB_group	11809767	LTP	0.18	MOD_PKA_1	-	-	0.10	2R4R	28.69%

Substrate:

BIRC4 (caspase inhibitor activity, protein binding)

Seq-ID:

P98170 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13839   CASP3_HUMAN
MINT-14016   MAGD1_HUMAN
MINT-25026   CASP9_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
caspase inhibitor activity, zinc ion binding, ligase activity, protein binding	cytosol	apoptosis, anti-apoptosis, response to DNA damage stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	87	DSAVGRHRKVSPNCRFINGFY	PKB_group	14645242	LTP	1.00		-	BIR	0.23	2POI	16.39%

Substrate:

BRCA1 (Breast cancer type 1 susceptibility protein)

Seq-ID:

P38398 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13705   JAK2_HUMAN
MINT-13786   ESR1_HUMAN
MINT-14573   SMC1A_HUMAN
MINT-16089   BRAP_HUMAN
MINT-16161   P53_HUMAN
MINT-16217   CREB1_HUMAN
MINT-16582   JAK1_HUMAN
MINT-19473   FACD2_HUMAN
MINT-19477   FANCA_HUMAN
MINT-25055   BARD1_HUMAN
MINT-77954   VE7_HPV16
MINT-2490745   H4_HUMAN
MINT-2791487   RD23B_HUMAN
MINT-5115454   FANCJ_HUMAN
MINT-7213847   ABL1_HUMAN
MINT-7250578   NCK1_HUMAN
MINT-7251658   P85A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding, identical protein binding, ubiquitin protein ligase binding, androgen receptor binding, RNA binding, transcription coactivator activity, zinc ion binding, tubulin binding, ubiquitin-protein ligase activity	ribonucleoprotein complex, gamma-tubulin ring complex, nucleoplasm, BRCA1-BARD1 complex, BRCA1-A complex	positive regulation of gene-specific transcription from RNA polymerase II promoter, negative regulation of centriole replication, response to estrogen stimulus, apoptosis, chromosome segregation, cellular response to indole-3-methanol, fatty acid biosynthetic process, regulation of transcription from RNA polymerase III promoter, cell cycle, postreplication repair, G2/M transition DNA damage checkpoint, positive regulation of protein ubiquitination, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, negative regulation of transcription, positive regulation of DNA repair, negative regulation of fatty acid biosynthetic process, androgen receptor signaling pathway, regulation of cell proliferation, protein K6-linked ubiquitination, DNA damage response, signal transduction resulting in induction of apoptosis, double-strand break repair via homologous recombination, response to ionizing radiation, protein autoubiquitination

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	509	TNKLKRKRRPTSGLHPEDFIK	PKB_group	10542266	LTP	1.00	MOD_PKB_1	-	-	0.65	-	-

Substrate:

cAMP-dependent protein kinase type II-beta regulatory subunit (cAMP-dependent protein kinase type II-beta regulatory chain)

Seq-ID:

P31323 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	cytosol	intracellular signaling pathway, signal transduction, activation of protein kinase A activity, regulation of protein amino acid phosphorylation, hormone-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	114	PVINRFTRRASVCAEAYNPDE	PKB_group	7479855	LTP	0.98	MOD_PKA_1	-	-	0.44	-	medium

Substrate:

Caspase 9 (Cysteine protease)

Seq-ID:

P55211 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15372   APAF_HUMAN
MINT-18815   CASP3_HUMAN
MINT-25026   XIAP_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
enzyme activator activity, cysteine-type endopeptidase activity, protein binding	cytosol	proteolysis, activation of caspase activity by cytochrome c

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	196	DCEKLRRRFSSLHFMVEVKGD	PKB_group	9812896	LTP	0.67	MOD_PKB_1	-	CASc	0.15	1NW9	40.16%

Substrate:

CD136 (Receptor tyrosine kinase)

Seq-ID:

Q04912 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6539679 CBL_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
macrophage colony-stimulating factor receptor activity, ATP binding, protein binding	integral to plasma membrane	positive regulation of cell proliferation, protein amino acid phosphorylation, cellular component movement, single fertilization, transmembrane receptor protein tyrosine kinase signaling pathway, multicellular organismal development, defense response

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1394	PGNVRRPRPLSEPPRPT	PKB_group	14505491	LTP	0.05	MOD_PKB_1	-	-	0.90	-	low

Substrate:

CENTB1 (GTPase-activating protein)

Seq-ID:

Q15027 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7244482   ABL1_HUMAN
MINT-7245778   SRC_HUMAN
MINT-7248706   NCK1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ARF GTPase activator activity, zinc ion binding, phospholipase C activity, protein binding		lipid metabolic process, protein transport, regulation of ARF GTPase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	554	PKPSIRPRPGSLRSKPEPPSE	PKB_group	16256741	LTP	0.07	MOD_PKB_1	-	-	0.89	-	medium

Substrate:

CHK1 (Serine/threonine-protein kinase Chk1)

Seq-ID:

O14757 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51394   CSK2B_HUMAN
MINT-1958329   P53_HUMAN
MINT-4793746   RB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein binding	condensed nuclear chromosome, microtubule organizing center, nucleoplasm	protein amino acid phosphorylation, regulation of cyclin-dependent protein kinase activity, senescence, DNA repair, reciprocal meiotic recombination, negative regulation of cell proliferation, DNA damage checkpoint, gamete generation, DNA replication

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	280	KKGAKRPRVTSGGVSESPSGF	PKB_group	12062056	LTP	0.04	MOD_PKB_1	-	-	0.63	2HOG	132.79%

Substrate:

Cyclin dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1))

Seq-ID:

P46527 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-17680   AKT1_HUMAN
MINT-17889   1433T_HUMAN
MINT-63858   GDIR1_HUMAN
MINT-1779946   MCM7_HUMAN
MINT-3379700   CDK2_HUMAN
MINT-3379718   CDK4_HUMAN
MINT-7219650   GRB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cyclin-dependent protein kinase inhibitor activity, transforming growth factor beta receptor, cytoplasmic mediator activity, protein binding	cytosol, nucleus	negative regulation of kinase activity, regulation of cyclin-dependent protein kinase activity, negative regulation of cell proliferation, negative regulation of cell growth, cell cycle arrest, G1/S transition of mitotic cell cycle, autophagic cell death, cellular response to lithium ion, induction of apoptosis, negative regulation of gene-specific transcription

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	10	MSNVRVSNGSPSLERMDARQ	PKB_group	16780593	LTP	0.28		-	-	0.76	-	-
T	157	QCAGIRKRPATDDSSTQNKRA	PKB_group	12244301	LTP	0.94	MOD_PKB_1	-	-	0.85	-	-
T	157	QCAGIRKRPATDDSSTQNKRA	PKB_group	12244302	LTP	0.94	MOD_PKB_1	-	-	0.85	-	-
T	157	QCAGIRKRPATDDSSTQNKRA	PKB_group	12244303	LTP	0.94	MOD_PKB_1	-	-	0.85	-	-

Substrate:

Desmoyokin (Neuroblast differentiation associated protein AHNAK (Desmoyokin))

Seq-ID:

Q09666 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3318854 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	nucleus	nervous system development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2852	KSKKPRHRSNSFSDEREFSGP	PKB_group	11535620	LTP	-	MOD_PKB_1	-	-	0.75	-	medium

Substrate:

E1A-associated protein p300 (Transcription regulatory protein)

Seq-ID:

Q09472 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13681   P73_HUMAN
MINT-17787   GATA4_MOUSE
MINT-50178   TF65_HUMAN
MINT-69559   VE7_HPV16
MINT-2584615   TF2B_HUMAN
MINT-2831131   ABL1_HUMAN
MINT-2982535   HIPK2_HUMAN
MINT-2982660   RUNX1_HUMAN
MINT-2983397   CDK2_HUMAN
MINT-4790867   ITF2_HUMAN
MINT-4791678   HIF1A_HUMAN
MINT-4979756   CREB1_MOUSE
MINT-5209851   CREB1_HUMAN
MINT-6628502   LT_SV40
MINT-6665134   E1A_ADE05
MINT-6743403   STRAP_HUMAN
MINT-7263630   P53_HUMAN
MINT-7943702   SENP3_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
histone acetyltransferase activity, beta-catenin binding, transcription coactivator activity, zinc ion binding	cytoplasm	transcription, response to hypoxia, histone H4 acetylation, apoptosis, positive regulation of transcription factor activity, cell cycle, N-terminal peptidyl-lysine acetylation, interspecies interaction between organisms, positive regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1834	QAQMLRRRMASMQRTGVVGQQ	PKB_group	11116148	LTP	1.00	MOD_PKB_1	-	-	0.77	-	medium

Substrate:

FANCA (DNA binding protein)

Seq-ID:

O15360 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19440   FANCG_HUMAN
MINT-19442   SPTA2_HUMAN
MINT-19465   SMCA4_HUMAN
MINT-19477   BRCA1_HUMAN
MINT-45825   FANCE_HUMAN
MINT-4789089   FP100_HUMAN
MINT-7244998   SRC_HUMAN
MINT-7247170   FYN_HUMAN
MINT-7248802   NCK1_HUMAN
MINT-7252294   P85A_HUMAN
MINT-7252846   PLCG1_HUMAN
MINT-7253206   GRB2_HUMAN
MINT-7253902   CRK_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cytoplasm, nucleus	protein complex assembly, DNA repair

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1149	LNACLRSRDPSLMVDFILAKC	PKB_group	11855836	LTP	0.87	MOD_PKB_1	-	-	0.04	-	low

Substrate:

Forkhead box protein O1A (Forkhead box protein O1A)

Seq-ID:

Q12778 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, transcription activator activity, protein binding	cytosol, nucleoplasm	transcription, anti-apoptosis, negative regulation of stress-activated MAPK cascade, positive regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	24	FEPLPRPRSCTWPLPRPEFSQ	PKB_group	10358014	LTP	1.00	MOD_PKB_1	YWHAG 14-3-3; YWHAH 14-3-3; YWHAZ 14-3-3	-	0.70	-	medium
T	24	FEPLPRPRSCTWPLPRPEFSQ	PKB_group	10358075	LTP	1.00	MOD_PKB_1	YWHAG 14-3-3; YWHAH 14-3-3; YWHAZ 14-3-3	-	0.70	-	medium
S	256	SGKSPRRRAASMDNNSKFAKS	PKB_group	10358014	LTP	1.00	MOD_PKB_1	-	Fork_head	0.74	-	medium
S	319	NWSTFRPRTSSNASTISGRLS	PKB_group	10358014	LTP	1.00	MOD_PKB_1	-	-	0.59	-	medium
S	319	NWSTFRPRTSSNASTISGRLS	PKB_group	10358075	LTP	1.00	MOD_PKB_1	-	-	0.59	-	medium
S	322	TFRPRTSSNASTISGRLSPIM	PKB_group	11311120	LTP	1.00	MOD_PKB_1	-	-	0.67	-	medium
S	325	PRTSSNASTISGRLSPIMTEQ	PKB_group	11980723	LTP	1.00	MOD_GSK3_1	-	-	0.73	-	medium

Substrate:

Forkhead box protein O1A (Forkhead box protein O1A)

Seq-ID:

Q9R1E0 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-5225582 CEBPA_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, transcription activator activity, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	transcription, blood vessel development, positive regulation of gluconeogenesis, anti-apoptosis, regulation of cell proliferation, insulin receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	24	FEPLPRQRSCTWPLPRPEFNQ	PKB_group	10377430	LTP	1.00	MOD_PKB_1	-	-	0.68	-	medium
S	253	SGKSPRRRAASMDNNSKFAKS	PKB_group	10377430	LTP	1.00	MOD_PKB_1	-	Fork_head	0.74	-	medium

Substrate:

Forkhead box protein O3A (Forkhead box protein O3A (Forkhead in rhabdomyosarcoma-like 1))

Seq-ID:

O43524 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-14323 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, protein kinase binding, transcription activator activity, sequence-specific DNA binding transcription factor activity	cytosol, nucleus	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription, apoptosis, positive regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	32	FEPQSRPRSCTWPLQRPELQA	PKB_group	11154281	LTP	1.00	MOD_PKB_1	YWHAZ 14-3-3	-	0.89	-	-
S	253	SGKAPRRRAVSMDNSNKYTKS	PKB_group	11154281	LTP	1.00	MOD_PKB_1	YWHAZ 14-3-3	Fork_head	0.71	2UZK	146.72%

Substrate:

Forkhead box protein O4 (Putative fork head domain transcription factor AFX1 (Forkhead box protein O4))

Seq-ID:

P98177 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7299691 OGT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
enzyme binding, transcription factor binding, sequence-specific DNA binding transcription factor activity	cytosol, nucleus	transcription from RNA polymerase II promoter, negative regulation of angiogenesis, G1 phase of mitotic cell cycle, negative regulation of cell proliferation, cell cycle arrest, negative regulation of smooth muscle cell differentiation, muscle organ development, regulation of transcription, DNA-dependent, cell differentiation, insulin receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	197	SGKAPRRRAASMDSSSKLLRG	PKB_group	11313479	LTP	1.00	MOD_PKB_1	YWHAZ 14-3-3	Fork_head	0.68	-	medium
S	262	MWTTFRPRSSSNASSVSTRLS	PKB_group	11313479	LTP	1.00	MOD_PKB_1	-	-	0.56	-	medium
S	262	MWTTFRPRSSSNASSVSTRLS	PKB_group	11689711	LTP	1.00	MOD_PKB_1	-	-	0.56	-	medium
S	262	MWTTFRPRSSSNASSVSTRLS	PKB_group	16272144	LTP	1.00	MOD_PKB_1	-	-	0.56	-	medium
T	451	ASAPIPKALGTPVLTPPTEAA	PKB_group	11689711	LTP	0.01	MOD_ProDKin_1	-	-	0.68	-	medium

Substrate:

Forkhead box protein O4 (Putative fork head domain transcription factor AFX1 (Forkhead box protein O4))

Seq-ID:

Q9WVH3 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, transcription activator activity, enzyme binding, transcription factor binding, sequence-specific DNA binding transcription factor activity	cytosol, nucleus	transcription, negative regulation of angiogenesis, G1 phase of mitotic cell cycle, negative regulation of cell proliferation, cell cycle arrest, negative regulation of smooth muscle cell differentiation, muscle organ development, mitotic cell cycle G2/M transition DNA damage checkpoint, regulation of transcription, DNA-dependent, cell differentiation, insulin receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	32	FEPQSRPRSCTWPLPRPDLAT	PKB_group	14690436	LTP	1.00	MOD_PKB_1	-	-	0.79	-	medium
S	197	GGKAPRRRAASMDSSSKLLRG	PKB_group	14690436	LTP	1.00	MOD_PKB_1	-	Fork_head	0.71	-	medium

Substrate:

Gab2 (Adaptor molecule)

Seq-ID:

Q9UQC2 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14688   SHC1_HUMAN
MINT-56633   MK03_HUMAN
MINT-68496   P85A_HUMAN
MINT-7220613   GRB2_HUMAN
MINT-7300434   1433B_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,4,5-trisphosphate binding, transmembrane receptor protein tyrosine kinase adaptor protein activity	plasma membrane, cytoplasm	positive regulation of cell proliferation, phosphoinositide-mediated signaling, positive regulation of mast cell degranulation, osteoclast differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	159	SQHLLRERKSSAPSHSSQPTL	PKB_group	11782427	LTP	0.66	MOD_PKB_1	-	-	0.61	-	low

Substrate:

GATA1 (transcription factor activity)

Seq-ID:

P15976 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
zinc ion binding, sequence-specific DNA binding transcription factor activity	nucleolus	transcription, regulation of transcription from RNA polymerase II promoter, multicellular organismal development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	310	DGIQTRNRKASGKGKKKRGSS	PKB_group	16107690	LTP	1.00	MOD_PKB_1	-	-	0.79	-	medium

Substrate:

Grb10 (Adapter molecule)

Seq-ID:

Q60760 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51135   PERQ2_MOUSE
MINT-73463   INSR_MOUSE
MINT-73466   INSR_HUMAN
MINT-73467   IGF1R_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
insulin receptor binding, SH3/SH2 adaptor activity, phosphotyrosine binding	cytosol	negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of glucose import, insulin-like growth factor receptor signaling pathway, positive regulation of vascular endothelial growth factor receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	455	PPFNAPMRSVSENSLVAMDFS	PKB_group	15722337	LTP	1.00		-	BPS	0.37	-	low

Substrate:

GSK-3 alpha (Glycogen synthase kinase-3 alpha)

Seq-ID:

P49840 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-4544606 AXN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, tau-protein kinase activity, ATP binding, protein kinase A catalytic subunit binding	beta-catenin destruction complex, cytosol	positive regulation of protein catabolic process, protein amino acid phosphorylation, negative regulation of insulin receptor signaling pathway, negative regulation of transferase activity, negative regulation of glucose import, insulin receptor signaling pathway, negative regulation of UDP-glucose catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	PGGSGRARTSSFAEPGGGGGG	PKB_group	11577096	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKB_group	11563975	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKB_group	11340086	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium

Substrate:

Huntingtin (DNA binding protein)

Seq-ID:

P42858 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14843   SP1_HUMAN
MINT-15358   OPTN_HUMAN
MINT-3978197   UT14A_HUMAN
MINT-3978299   ELP1_HUMAN
MINT-3978316   KU70_HUMAN
MINT-3978554   PROF2_HUMAN
MINT-3978605   MTSS1_HUMAN
MINT-3978637   GASP2_HUMAN
MINT-3981338   GIT1_HUMAN
MINT-3981354   CHD3_HUMAN
MINT-7102030   PR40A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription corepressor activity, microtubule binding, transporter activity	Golgi apparatus, nuclear periphery, soluble fraction	induction of apoptosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	421	EESGGRSRSGSIVELIAGGGS	PKB_group	12062094	LTP	1.00	MOD_PKB_1	-	-	0.54	-	medium
S	421	EESGGRSRSGSIVELIAGGGS	PKB_group	14725621	LTP	1.00	MOD_PKB_1	-	-	0.54	-	medium

Substrate:

IKK-alpha (Inhibitor of nuclear factor kappa B kinase alpha subunit)

Seq-ID:

O15111 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-47841   IKBA_HUMAN
MINT-47853   IKBB_HUMAN
MINT-47951   CDC37_HUMAN
MINT-47955   IKKB_HUMAN
MINT-48052   CALM_HUMAN
MINT-48053   HS90A_HUMAN
MINT-48054   TBB5_HUMAN
MINT-48055   MYH14_HUMAN
MINT-48056   TBB4_HUMAN
MINT-48057   MYH9_HUMAN
MINT-48058   TPM3_HUMAN
MINT-48059   MYL6_HUMAN
MINT-48060   FKBP5_HUMAN
MINT-48062   HS90B_HUMAN
MINT-48063   ML12A_HUMAN
MINT-48064   MYO1D_HUMAN
MINT-48137   NEMO_HUMAN
MINT-48382   M3K3_HUMAN
MINT-48643   NFKB1_HUMAN
MINT-48699   NFKB2_HUMAN
MINT-48791   M3K14_HUMAN
MINT-48981   RELB_HUMAN
MINT-50107   TF65_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
identical protein binding, IkappaB kinase activity, ATP binding	nucleus	I-kappaB phosphorylation, immune response

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	23	GPWEMRERLGTGGFGNVCLYQ	PKB_group	10485710	LTP	0.18	MOD_PKB_1	-	S_TKc	0.20	-	medium

Substrate:

Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)

Seq-ID:

P35569 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-58476   NUCL_MOUSE
MINT-6381887   P85A_MOUSE
MINT-6793439   PTN1_HUMAN
MINT-6794075   INSR_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoinositide 3-kinase binding, insulin-like growth factor receptor binding, insulin receptor binding, SH2 domain binding	microsome, cytosol, nucleus	positive regulation of mesenchymal cell proliferation, positive regulation of cell migration, protein kinase B signaling cascade, mammary gland development, insulin receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	302	VGLTRRSRTESITATSPASMV	PKB_group	11701324	LTP	1.00	MOD_PKB_1	-	-	0.78	-	-

Substrate:

IRAK1 (Interleukin-1 receptor-associated kinase 1)

Seq-ID:

P51617 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-49176 TAB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
NF-kappaB-inducing kinase activity, protein heterodimerization activity, protein homodimerization activity, transcription activator activity, ATP binding, protein binding	cytosol, interleukin-1 receptor complex	negative regulation of NF-kappaB transcription factor activity, regulation of cytokine-mediated signaling pathway, activation of NF-kappaB-inducing kinase activity, anti-apoptosis, lipopolysaccharide-mediated signaling pathway, protein oligomerization, protein amino acid autophosphorylation, transmembrane receptor protein serine/threonine kinase signaling pathway, response to interleukin-1, positive regulation of NF-kappaB transcription factor activity, toll-like receptor 2 signaling pathway, MyD88-dependent toll-like receptor signaling pathway, interleukin-1-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	100	LQLLRARDIITAWHPPAPLPS	PKB_group	11976320	LTP	0.05		-	Death	0.38	-	low

Substrate:

MAP2K4 (Serine/threonine kinase)

Seq-ID:

P45985 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7263269 ARRB1_HUMAN
MINT-7263286 ARRB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein tyrosine kinase activity, protein binding		protein amino acid phosphorylation, JNK cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	80	NPHIERLRTHSIESSGKLKIS	PKB_group	11707464	LTP	0.15	MOD_PKB_1	-	-	0.60	-	medium

Substrate:

MAP3K11 (Mitogen activated protein kinase kinase kinase 11)

Seq-ID:

Q16584 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7214892 M4K1_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
JUN kinase kinase kinase activity, protein homodimerization activity, ATP binding	centrosome, microtubule	G1 phase of mitotic cell cycle, activation of JUN kinase activity, protein oligomerization, protein amino acid autophosphorylation, microtubule-based process, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	674	PGGPGRERGESPTTPPTPTPA	PKB_group	12458207	LTP	0.45		-	-	0.99	-	low

Substrate:

MAP3K11 (Mitogen activated protein kinase kinase kinase 11)

Seq-ID:

Q80XI6 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

Molecular Function	Cellular Component	Biological Process
ATP binding

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	675	PGGLSRERGESPTAPPPAQMP	PKB_group	12458207	LTP	0.99		-	-	0.98	-	low

Substrate:

MAP3K5 (Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.1. -) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1)

Seq-ID:

Q99683 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16168   M3K3_HUMAN
MINT-18083   M3K2_HUMAN
MINT-18459   DAB2P_HUMAN
MINT-3391607   MP2K7_HUMAN
MINT-7263196   ARRB2_HUMAN
MINT-7263254   ARRB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
magnesium ion binding, protein homodimerization activity, ATP binding, caspase activator activity, MAP kinase kinase kinase activity		induction of apoptosis by extracellular signals, apoptosis, activation of JUN kinase activity, interspecies interaction between organisms

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	83	SSSATRGRGSSVGGGSRRTTV	PKB_group	11154276	LTP	0.18	MOD_PKB_1	-	-	0.61	-	-
S	83	SSSATRGRGSSVGGGSRRTTV	PKB_group	14500571	LTP	0.18	MOD_PKB_1	-	-	0.61	-	-

Substrate:

MAP3K8 (Serine/threonine kinase)

Seq-ID:

P41279 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-47827   NFKB1_HUMAN
MINT-47831   REL_HUMAN
MINT-47914   NFKB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
magnesium ion binding, ATP binding, MAP kinase kinase kinase activity, protein binding	cytosol	protein amino acid phosphorylation, cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	400	PPREDQPRCQSLDSALLERKR	PKB_group	12138205	LTP	0.13		-	-	0.54	-	medium

Substrate:

Mdm2 (Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2. -) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2))

Seq-ID:

Q00987 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-16320   ARRB2_HUMAN
MINT-58469   MED1_HUMAN
MINT-58599   CHK2_HUMAN
MINT-68739   HIPK2_HUMAN
MINT-1776635   RB_HUMAN
MINT-3376147   ARBK1_HUMAN
MINT-3391121   RL5_HUMAN
MINT-4793330   PML_HUMAN
MINT-6540837   PSME3_HUMAN
MINT-6540889   P53_HUMAN
MINT-6801697   DAXX_HUMAN
MINT-6823537   AKT1_HUMAN
MINT-6823574   PIM2_HUMAN
MINT-6823669   FKBP3_HUMAN
MINT-7013760   RYBP_HUMAN
MINT-7266353   PLK1_HUMAN
MINT-7718939   SNAI1_HUMAN
MINT-7904837   GORAB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
identical protein binding, p53 binding, enzyme binding, zinc ion binding, basal transcription repressor activity, ubiquitin-protein ligase activity	plasma membrane, endocytic vesicle membrane, cytosol, nucleolus, nucleoplasm, insoluble fraction, protein complex	positive regulation of cell proliferation, protein complex assembly, protein destabilization, positive regulation of mitotic cell cycle, negative regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, interspecies interaction between organisms, negative regulation of cell cycle arrest, negative regulation of transcription from RNA polymerase II promoter, protein localization in nucleus, establishment of protein localization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	166	PSTSSRRRAISETEENSDELS	PKB_group	11504915	LTP	0.09	MOD_PKB_1	-	-	0.78	-	medium
S	186	SGERQRKRHKSDSISLSFDES	PKB_group	11504915	LTP	0.97	MOD_PKB_1	-	-	0.53	-	medium
S	188	ERQRKRHKSDSISLSFDESLA	PKB_group	15169778	LTP	1.00	MOD_PKB_1	-	-	0.46	-	medium
S	188	ERQRKRHKSDSISLSFDESLA	PKB_group	15527798	LTP	1.00	MOD_PKB_1	-	-	0.46	-	medium

Substrate:

mTOR (Cell cycle control protein)

Seq-ID:

P42345 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13782   4EBP1_MOUSE
MINT-16737   AKT1_HUMAN
MINT-17466   PDPK1_HUMAN
MINT-3307838   1433Z_HUMAN
MINT-7222784   P53_HUMAN
MINT-7222793   Q8N6M7_HUMAN
MINT-7556099   RPTOR_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, phosphoprotein binding	Golgi membrane, TORC1 complex, TORC2 complex, phosphoinositide 3-kinase complex, mitochondrial outer membrane, endoplasmic reticulum membrane	TOR signaling cascade, response to amino acid stimulus, cell growth, peptidyl-serine phosphorylation, response to nutrient, protein amino acid autophosphorylation, protein catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	2446	TKGNKRSRTRTDSYSAGQSVE	PKB_group	10910062	LTP	0.11	MOD_PKB_1	-	PI3Kc	0.60	-	medium
S	2448	GNKRSRTRTDSYSAGQSVEIL	PKB_group	10910062	LTP	0.20	MOD_PKB_1	-	PI3Kc	0.52	-	medium
S	2448	GNKRSRTRTDSYSAGQSVEIL	PKB_group	10567225	LTP	0.20	MOD_PKB_1	-	PI3Kc	0.52	-	medium

Substrate:

Neutrophil cytosol factor 1 (Neutrophil cytosol factor 1)

Seq-ID:

P14598 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-58638   TF65_HUMAN
MINT-66383   TRIM9_HUMAN
MINT-74863   ACTB_HUMAN
MINT-3973484   KPCA_HUMAN
MINT-3973536   KPCD_HUMAN
MINT-7135171   GNAI2_HUMAN
MINT-7300360   NCF4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3 domain binding, phosphoinositide binding, GTPase activity, GTP binding, electron carrier activity	cytosol, NADPH oxidase complex, soluble fraction	protein targeting to membrane, superoxide anion generation, cellular defense response, innate immune response, cell communication, respiratory burst

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	304	IKRGAPPRRSSIRNAHSIHQR	PKB_group	8626435	LTP	0.09		-	-	0.77	1NG2	57.38%
S	304	IKRGAPPRRSSIRNAHSIHQR	PKB_group	7520867	LTP	0.09		-	-	0.77	1NG2	57.38%
S	304	IKRGAPPRRSSIRNAHSIHQR	PKB_group	12734380	LTP	0.09		-	-	0.77	1NG2	57.38%
S	328	RLSQDAYRRNSVRFLQQRRRQ	PKB_group	7520867	LTP	0.99	MOD_PKA_1	-	-	0.56	1NG2	0.00%
S	328	RLSQDAYRRNSVRFLQQRRRQ	PKB_group	12734380	LTP	0.99	MOD_PKA_1	-	-	0.56	1NG2	0.00%

Substrate:

Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)

Seq-ID:

P29474 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
arginine binding, actin monomer binding, heme binding, cadmium ion binding, NADP or NADPH binding, FAD binding, calmodulin binding, nitric-oxide synthase activity, tetrahydrobiopterin binding, FMN binding	Golgi membrane, caveola, cytosol, cytoskeleton	regulation of blood vessel size, positive regulation of vasodilation, oxidation reduction, blood vessel remodeling, regulation of systemic arterial blood pressure by endothelin, anti-apoptosis, response to heat, positive regulation of guanylate cyclase activity, arginine catabolic process, negative regulation of muscle hyperplasia, positive regulation of angiogenesis, nitric oxide biosynthetic process, smooth muscle hyperplasia, endothelial cell migration, negative regulation of platelet activation, response to fluid shear stress, mitochondrion organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	615	QHKSYKIRFNSISCSDPLVSS	PKB_group	12171920	LTP	0.23		-	Flavodoxin_1	0.19	-	-
S	1177	QEVTSRIRTQSFSLQERQLRG	PKB_group	10376603	LTP	0.16	MOD_PKB_1	-	-	0.41	-	-
S	1177	QEVTSRIRTQSFSLQERQLRG	PKB_group	12446767	LTP	0.16	MOD_PKB_1	-	-	0.41	-	-
S	1177	QEVTSRIRTQSFSLQERQLRG	PKB_group	12791703	LTP	0.16	MOD_PKB_1	-	-	0.41	-	-
S	1177	QEVTSRIRTQSFSLQERQLRG	PKB_group	16043647	LTP	0.16	MOD_PKB_1	-	-	0.41	-	-
S	1179	VTSRIRTQSFSLQERQLRGAV	PKB_group	12501214	LTP	0.08	MOD_PKB_1	-	-	0.37	-	-

Substrate:

NUAK1 (ser/thr kinase)

Seq-ID:

O60285 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, metal ion binding, ATP binding, protein binding		protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	600	ENRPARQRIRSCVSAENFLQI	PKB_group	12409306	LTP	0.07	MOD_PKB_1	-	-	0.39	-	medium

Substrate:

Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR (Early response protein NAK1) (TR3 orphan receptor))

Seq-ID:

P22736 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-2859701 ATX1_HUMAN
MINT-4049689 P53_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
zinc ion binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity	nucleoplasm	transcription

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	351	SLKGRRGRLPSKPKQPPDASP	PKB_group	11274386	LTP	1.00	MOD_PKB_1	-	-	0.77	1CIT	100.82%

Substrate:

p21 (Cyclin-dependent kinase inhibitor 1 (p21))

Seq-ID:

P38936 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50392   CC45L_HUMAN
MINT-50407   CDC6_HUMAN
MINT-50418   CDK4_HUMAN
MINT-50421   CDK6_HUMAN
MINT-50432   CCNB2_HUMAN
MINT-50437   CCND1_HUMAN
MINT-50441   CCND3_HUMAN
MINT-50445   GEMI_HUMAN
MINT-50660   CCNB1_HUMAN
MINT-73322   VE7_HPV16
MINT-73323   CDK2_HUMAN
MINT-1774121   SKP2_HUMAN
MINT-1780042   MCM7_HUMAN
MINT-1891378   P53_HUMAN
MINT-2635177   CCNE1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cyclin-dependent protein kinase inhibitor activity, metal ion binding	cytosol, cyclin-dependent protein kinase holoenzyme complex, nucleoplasm, PCNA-p21 complex	cellular response to extracellular stimulus, positive regulation of fibroblast proliferation, senescence, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, negative regulation of cell proliferation, negative regulation of cell growth, cell cycle arrest, G1/S transition of mitotic cell cycle, induction of apoptosis by intracellular signals, Ras protein signal transduction, G2/M transition of mitotic cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	145	GDSQGRKRRQTSMTDFYHSKR	PKB_group	11756412	LTP	0.19	MOD_PKB_1	-	-	0.69	-	medium
T	145	GDSQGRKRRQTSMTDFYHSKR	PKB_group	16982699	LTP	0.19	MOD_PKB_1	-	-	0.69	-	medium
T	145	GDSQGRKRRQTSMTDFYHSKR	PKB_group	11463845	LTP	0.19	MOD_PKB_1	-	-	0.69	-	medium
S	146	DSQGRKRRQTSMTDFYHSKRR	PKB_group	11756412	LTP	0.03	MOD_PKB_1	-	-	0.65	-	medium

Substrate:

p21-Rac1 (GTPase)

Seq-ID:

P63000 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19610   NONO_MOUSE
MINT-19641   RBM39_MOUSE
MINT-19851   EVI5_MOUSE
MINT-51615   FHOD1_HUMAN
MINT-2490678   KPCA_HUMAN
MINT-4298452   GDIR1_HUMAN
MINT-4298550   SET_HUMAN
MINT-4507979   FRK_HUMAN
MINT-6504419   RTKN_HUMAN
MINT-6743318   VAV_HUMAN
MINT-7145306   ARHG7_HUMAN
MINT-7217644   PAK1_HUMAN
MINT-7219402   SPN90_HUMAN
MINT-7229970   PLCG1_HUMAN
MINT-7230086   PAK2_HUMAN
MINT-7288697   FLNB_HUMAN
MINT-7305963   DOCK1_HUMAN
MINT-7305987   DOCK2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
thioesterase binding, GTPase activity, GTP binding, GTP-dependent protein binding	plasma membrane, cytosol, melanosome	localization within membrane, induction of apoptosis by extracellular signals, negative regulation of receptor-mediated endocytosis, positive regulation of lamellipodium assembly, apoptosis, cellular component movement, actin filament polymerization, anatomical structure morphogenesis, inflammatory response, regulation of hydrogen peroxide metabolic process, cell-matrix adhesion, positive regulation of Rho protein signal transduction, regulation of respiratory burst, lamellipodium assembly, small GTPase mediated signal transduction, ruffle organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	71	QEDYDRLRPLSYPQTDVFLIC	PKB_group	10617634	LTP	1.00	MOD_PKB_1	-	RHO	0.11	1MH1	6.56%

Substrate:

PDCD4 (Programmed cell death 4)

Seq-ID:

Q53EL6 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
RNA binding, protein binding	cytosol, nucleus	apoptosis, negative regulation of JUN kinase activity, cell aging, negative regulation of transcription, negative regulation of cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	67	AKAKRRLRKNSSRDSGRGDSV	PKB_group	16357133	LTP	1.00	MOD_PKB_1	-	-	0.72	-	-
S	457	CPSRGRKRFVSEGDGGRLKPE	PKB_group	16357133	LTP	1.00	MOD_PKB_1	-	-	0.42	-	-

Substrate:

PEA15 (astrocytic phosphoprotein PEA-15 (from PhosphoBase))

Seq-ID:

Q15121 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-4300420 MK01_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cytoplasm, microtubule associated complex	carbohydrate transport, negative regulation of glucose import, apoptosis, anti-apoptosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	116	KKYKDIIRQPSEEEIIKLAPP	PKB_group	12808093	LTP	1.00		-	-	0.43	-	-

Substrate:

Phosphodiesterase 3B (Enzyme: Phosphodiesterase)

Seq-ID:

Q61409 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase B binding, metal ion binding	microsome, cytosol, integral to membrane, Golgi apparatus, endoplasmic reticulum	glucose homeostasis, endocrine pancreas development, signal transduction, cellular response to insulin stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	273	KVPVIRPRRRSSCVSLGESAA	PKB_group	10454575	LTP	1.00	MOD_PKB_1	-	-	0.23	-	medium

Substrate:

PIP5K (FYVE finger-containing phosphoinositide kinase)

Seq-ID:

Q9Y2I7 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7277788 VAC14_HUMAN
MINT-7971800 DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
1-phosphatidylinositol-3-phosphate 5-kinase activity, 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding, protein binding	early endosome membrane, membrane raft	cellular protein metabolic process, phosphatidylinositol metabolic process, retrograde transport, endosome to Golgi, protein localization in nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	307	GKSPARNRSASITNLSLDRSG	PKB_group	15546921	LTP	0.85	MOD_PKB_1	-	-	0.57	-	low

Substrate:

Raf1 (RAF proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P04049 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19324   KPYM_HUMAN
MINT-24923   RAP1A_HUMAN
MINT-45800   1433Z_HUMAN
MINT-51053   K1C19_HUMAN
MINT-51055   K1C18_HUMAN
MINT-51056   K2C8_HUMAN
MINT-56513   CNKR1_HUMAN
MINT-3389399   PAK1_HUMAN
MINT-3389607   PEBP1_HUMAN
MINT-3975386   1433S_HUMAN
MINT-6946517   RASH_HUMAN
MINT-7014370   MP2K1_HUMAN
MINT-7014449   AKT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, metal ion binding, receptor signaling protein activity, ATP binding, protein binding	plasma membrane, cytosol, mitochondrial outer membrane	protein amino acid phosphorylation, negative regulation of cell proliferation, apoptosis, Ras protein signal transduction, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	259	GSLSQRQRSTSTPNVHMVSTT	PKB_group	10576742	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.73	-	medium

Substrate:

S1P receptor EDG1 (G protein coupled receptor)

Seq-ID:

P21453 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
lysosphingolipid and lysophosphatidic acid receptor activity	plasma membrane, integral to membrane	cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	236	SLVRTRSRRLTFRKNISKASR	PKB_group	11583630	LTP	0.18	MOD_PKB_1	-	7tm_1	0.13	-	medium

Substrate:

Serine/threonine-protein kinase WNK1 (Ser/Thr protein kinase family)

Seq-ID:

Q9H4A3 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-5207758 OXSR1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, protein kinase inhibitor activity, ATP binding, protein binding	cytoplasm	protein amino acid phosphorylation, ion transport, intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	60	RTEEYRRRRHTMDKDSRGAAA	PKB_group	14611643	LTP	1.00	MOD_PKB_1	-	-	0.89	-	medium

Substrate:

TBC1D4 (Unclassified)

Seq-ID:

O60343 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3319865 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rab GTPase activator activity	cytoplasm	regulation of Rab GTPase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	642	DSPQFRRRAHTFSHPPSSTKR	PKB_group	11994271	LTP	0.95	MOD_PKB_1	-	-	0.79	-	medium
T	642	DSPQFRRRAHTFSHPPSSTKR	PKB_group	17617058	LTP	0.95	MOD_PKB_1	-	-	0.79	-	medium

Substrate:

Telomerase reverse transcriptase (Telomerase reverse transcriptase)

Seq-ID:

O14746 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6742762 AKT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
telomeric RNA binding, telomeric template RNA reverse transcriptase activity, protein homodimerization activity, telomeric DNA binding	nuclear telomere cap complex, cytoplasm, nucleolus, telomerase holoenzyme complex, nucleoplasm	DNA strand elongation, senescence, anti-apoptosis, telomere maintenance via telomerase, telomere formation via telomerase

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	227	PAPGARRRGGSASRSLPLPKR	PKB_group	10224060	LTP	0.17	MOD_PKB_1	-	-	0.80	-	medium
S	824	CHHAVRIRGKSYVQCQGIPQG	PKB_group	10224060	LTP	0.08	MOD_PKB_1	-	-	0.12	-	medium

Substrate:

Tuberin (GTPase activating protein)

Seq-ID:

P49815 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14051   1433T_HUMAN
MINT-16238   TSC1_HUMAN
MINT-16580   1433F_HUMAN
MINT-17162   1433B_HUMAN
MINT-17710   1433S_HUMAN
MINT-3317863   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, GTPase activator activity	TSC1-TSC2 complex, Golgi apparatus, nucleus, perinuclear region of cytoplasm	neural tube closure, protein import into nucleus, regulation of insulin receptor signaling pathway, positive regulation of GTPase activity, insulin-like growth factor receptor signaling pathway, heart development, negative regulation of phosphoinositide 3-kinase cascade, superior temporal gyrus development, positive chemotaxis, protein kinase B signaling cascade, regulation of small GTPase mediated signal transduction, regulation of endocytosis, endocytosis, negative regulation of protein kinase B signaling cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	939	EKDSFRARSTSLNERPKSLRI	PKB_group	12150915	LTP	1.00	MOD_PKB_1	-	-	0.48	-	medium
S	939	EKDSFRARSTSLNERPKSLRI	PKB_group	15342917	LTP	1.00	MOD_PKB_1	-	-	0.48	-	medium
T	1462	SPSGLRPRGYTISDSAPSRRG	PKB_group	12150915	LTP	1.00	MOD_PKB_1	-	-	0.76	-	medium

Substrate:

Tyrosine-protein phosphatase, non-receptor type 1 (Protein tyrosine phosphatase 1B)

Seq-ID:

P18031 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51115   PPIP1_HUMAN
MINT-73489   CADH2_HUMAN
MINT-6744190   CSK21_HUMAN
MINT-6761890   GSK3B_HUMAN
MINT-6761899   ESR1_HUMAN
MINT-6762163   IKBA_HUMAN
MINT-6762380   PGFRB_HUMAN
MINT-6762549   PAXI_MOUSE
MINT-6762573   FAK1_MOUSE
MINT-6762866   IRS1_RAT
MINT-6763504   BCAR1_MOUSE
MINT-6763556   INSR_RAT
MINT-6764602   JAK2_HUMAN
MINT-6764613   STAT3_HUMAN
MINT-6764665   TRPV6_HUMAN
MINT-6764866   CAV1_HUMAN
MINT-6765163   PIAS1_HUMAN
MINT-6765185   SUMO1_HUMAN
MINT-6765318   CTND1_MOUSE
MINT-6765333   LPP_MOUSE
MINT-6765355   SRC8_MOUSE
MINT-6765370   ZO1_MOUSE
MINT-6765383   PLCG1_MOUSE
MINT-6765422   DOK1_MOUSE
MINT-6765439   EGFR_MOUSE
MINT-6765460   PGFRB_MOUSE
MINT-6787689   MET_HUMAN
MINT-6787710   ABL1_HUMAN
MINT-6793324   B3AT_HUMAN
MINT-6793358   EGFR_HUMAN
MINT-6793387   CAN1_HUMAN
MINT-6793394   CAN2_HUMAN
MINT-6793439   IRS1_MOUSE
MINT-6793452   INSR_MOUSE
MINT-6793484   BCAR1_HUMAN
MINT-6793722   AKT1_MOUSE
MINT-6793745   IRS1_HUMAN
MINT-6793782   TYK2_HUMAN
MINT-6793941   NTRK1_HUMAN
MINT-6793957   NTRK3_HUMAN
MINT-6793973   LTK_HUMAN
MINT-6793989   STA5A_HUMAN
MINT-6794005   STA5B_HUMAN
MINT-6794135   LAT_HUMAN
MINT-6794748   EPOR_HUMAN
MINT-6794792   GRB2_HUMAN
MINT-6794817   ITB3_HUMAN
MINT-6794878   ACTS_HUMAN
MINT-6794892   FAK1_HUMAN
MINT-6794946   INSR_HUMAN
MINT-6794972   KPCG_HUMAN
MINT-6795050   JAK2_MOUSE
MINT-6795199   SRC8_HUMAN
MINT-6795447   SRC_HUMAN
MINT-6796717   PLD2_HUMAN
MINT-6797067   CLK2_HUMAN
MINT-6797829   GHR_HUMAN
MINT-6799814   ROS_HUMAN
MINT-6800783   IGF1R_HUMAN
MINT-7972220   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein tyrosine phosphatase activity, zinc ion binding	cytosol, endoplasmic reticulum membrane	negative regulation of insulin receptor signaling pathway, signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	50	NKNRNRYRDVSPFDHSRIKLH	PKB_group	11579209	LTP	0.89		-	PTPc	0.45	2CM2	4.10%

Substrate:

YAP65 (Transcription regulatory protein)

Seq-ID:

P46937 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-18935   1433T_HUMAN
MINT-68603   NHRF2_HUMAN
MINT-72743   NHRF1_HUMAN
MINT-3317930   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription corepressor activity, transcription coactivator activity	cytoplasm, nucleus	transcription, hippo signaling cascade, contact inhibition, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	127	ALTPQHVRAHSSPASLQLGAV	PKB_group	12535517	LTP	1.00		YWHAQ 14-3-3	-	0.76	-	-

Substrate:

ZFP36L1 (mRNA binding, protein binding)

Seq-ID:

Q07352 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-66629 MK14_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
mRNA binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	regulation of mRNA stability

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	92	RDSRFRDRSFSEGGERLLPTQ	PKB_group	15538381	LTP	0.88	MOD_PKB_1	-	Tis11B_N	0.57	-	low